THE FIGHTF OR LAETRILE Filii liEN WEIPII 1111111 CANCER MICHAELL .C ULBERT Copyri©g h1t794b yM ichaeLl.C ulbert Allr ihgtsr eseerdv.N o poritono ft hibso okm ayb er epruocdedw ihtout writtpeenr imssiformno thep ubilsheexrc ebpyta reviewwheorm ay qutoe bripeafs sagecso ninne cwtiitoahn vrieew. MANUFACTUIRNET DH EU NITESDT ATEOSFA MERICA LibraorfCy o ngreCsast aloigniPn ugb licaDtaitoan Culbert,Mi chael1 1937- Vitamin B-17- -forbiddweena poang ainstc ancer. Bibligroaphy:p . 1. LaetrileI.. Title.[ DNLM: 1. Antineoplastic agents--Popuwloarrk s.QZ 201 C967v] RC271.13C84 616.9'94'061 74-12236 ISBN0 -87000-279-1 TO FRANK V.C ORTESE,p harmacainsdtA mericaniwshtoi, n spired WILLIAML OEB,n ewspapermwahno,i nsisted WA RREN BROWN,J R.n,e wspapermwahno,w asi ntrigued CONTENTS PREFACE 9 AcKNOWLEDGMENTS 15 I.A n ApricoPti otn T rial 21 2.F romD eathD'oso rT:h eL aetriRleec overies 35 3.T heB attolfeU northodoExnyt:e Jro hnB eard 47 4." My God,I tW orks!" 59 5.O fficialdRoems'pso nse: CracokndL oawent rile 73 6.T heC yanidHeu nters 84 7.T hatA stoundiVnigt amiBn1:1 91 8.F romM aniltao P alAo ltoL:a etriDleef'esn ders 101 9.A n InsideBra'tst lDee:a nB urka tW ork 108 I 0A.n drewM cNaughtoPni:o neoefrt heH umanS pirit 117 II.T reatiCnagn cewri tah FoodF actor 127 12.T heC aseA gainsLta etrile-AHnodp ef ort heF uture 133 APPENDicEIs.:T heN itrilosiinPd leasn atnsd A nimals 145 II.T heU nitarioarTn r ophobtliacs ThesiosfC ancer 165 IIIN.it rilosi(dL ease triles) 189 BIBLIOGRAPHY 205 INDEX 209 7 PREFACE Ast hbioso k twoep nrte tshsve,i taBmni( naL etrsitloewr)ay sf a frr om oveIrdn.e etdeh,t idoefi netreisntt h "ei elagllw,o trhlaepsirsc optic ta ncer curwea"gs or wnigi rreivbelrys. Theu nitosft hCeo mmittefeo Frre edoomfC hoiicnCe a ncTehrre aphya d gronwt o1 70n atidoena,wdn ii vnoeldvt housoafmn edmsb earnshd u nrdesdo f docsta,ol ralr gigunt htahte arreoe b viosuosmbleey en fiftrsov mti aimnBn . Moret ha4n3 ,000s ginatuhraebdse eanfx feitdo p etituirogniPsner gis dent andM rsN.io xnt oi netrnveep eornsatlol y atlhlceol wci an(liuh mant)e sting ofv timaiBnt 7a te(rL)i.l e Thep restiMgemiooruiSsal nlo- aeKttienCrga ncCeerne tri nN ew Yokrw as continwuiihtna gni mals tiueduss ings ustbthcaeenA . f risste sro ifte eshtasd beevne ry gas oeoncddo,s eruiseisdn ifgfe nrtse ourmcaeetr ifarlot mh fei rst hda fiaeldt oc onfirema rrtlehyset u sbl,u att ihdr sericeosml,pe tienMd a y 1974,c oinrfmaednde xpdaentdh fei rtsetsI tl se,a rned. Ont hbea siosf S loatnet-rKiensgu'cscu elas nsifmaelx rpeiemtnsp,or ­ tolcsot ot hFeo oadn Dd rugA dmintirosantf ioarn algteessoitfcts h seu ­b stanonch eu mawnesrb ee idnegsn idegi n nJewu,ih tt hferi sotff iicalalutyh or­ izeteds otnhs u maenxpse cdtt eof olloswohr ttlhye rteearf. TheN atioCnaanlcI entrsui etta nSdo uetrhRne searIcsnthi thudat iess ued antoherre podretn ytihneegfi faccoyf v itaBmtii7nnt ensgti iotn L ewis lung cancienmr i cbeu,tt he rweesrurele tbsu titnde eadt ibly t hNeC Ic'ys­ tocmhiersydt ivoinds riiecwthoor, a f niianbl l ast rbteeifrofirrneotgm h e fed­ earlp oshteh dao ccupiterhodgu hm ucohfh ipsr eosfsiloein,afa clc u"sce­edr taiunpp NeCr la dmintirsatsiopvkee sm.e.(nfo. )s cieincat niidfm omraflal­ siifciaotnasmo unttiocn orgr putiiontn h e soeftn hsCeeo n rgesosinaClo doef Ehtisc." InC ailofrinaa,c anrcp eattih edans ueSdt aondrfU niverfsoirrteu yfs itnog lehte bre t rteeawdi tthhc eo tnorverssuibaslt baunatcc eo,u dretin ehde arn ordwehri wcohu dl havaell owheedt ro r eicvedeo soefst hmee dicaitnt eh e uneirvys'ihstop sitTahlel. e gbaalt wtalse stiwlaly .u nder Andat ihdrt rifaoArllb anCya,lo rinfipah,y sniD criJ.ao hAn.R cihardson onc hrageosf denissipvniagtm iBnt (7aL etrhidale en)d iendB ekreylA-elbany MuniaclCi oprutC,a loirfniwati,ha nothhuenrjg u rayn da dissmaiolsf charegsT.he k ecyo ucrsateo pednt ehdeo ofrot rh lee gaittueis moeft ehs ub­ staansca ve i taimnmi enag vaimtimne toalbtihce r.a py Int hmee anet,ti hmmeo deorrnt hoadpporxo atcoch a ncreearmi dn veery mucah w eltoefcr o unisfonb,o tihnt hsee nosfee xactly what causes the diessaea,n dho wt hdei secaasbnee c urecdot,nrl odl aenmda ngaedT.h ea u­ thowra usp datoendt hciosm pilteoyxfp orbleamtts h seit xetehns cnicewer ­it erssme'i nr aofA mtehrei cCaann cSeoriec tiyn ASutug.s tin,ed ,u rFilnag. whitchhne ta iomnaj'rosc ancreearsr ehcesrr peortoentd h seat toef c ancer reseaarsoc fSh pr ign 1974.O uto fa s eoaf p aeprpser,s etnitoaannsdp a nel 9 deabtebse twnte hemeo sqtu aildei rfescehaersrcsi,e tnsat niidsn evsattiogirns thfeeid li nt hUeS. .Ae.m egretdh piisuc rte: • Thesp ecicfaiucos rce a sueosft hvea rihouumsac na ncaerrneso k tno wn evetnhu oghr,u nmsaj roiotpyii ontnh,ke no wledogfce ua soerc ausdeosen so t precltuhdeeeff i cacoyfc erttarienea nttms. • Theries n os epciicef videntcheav tri usaecsut alclayu csae ncienr humanesv,e tnh ouagn hum beorfv iurseasra es saotcewidi tthu msoyrs tems andv irusseese tmo c aucseear itkni dnso fc ancienir n v itlraor baotory studies. • Iti sn ostep ciflilckyano wnw hacta usane tasu rcaeltl obl e coamm ea ilg­ nnato ne. • Thev asitni cdenocfce a ncientr ih sc ournyit su ndoubtleikdnelyda ,t leaisnts ome wtaoty h,"e m an-dmea"a psecotfso ur "ciivzieledn"v i­ rnomnet-iwtahle lgecdac rigneoincf actaobruosn diinntg h aei wre b reathe andt hfeo owde e atY.e tth meo duosp eraonftd hie csraeic ongenrse amins hgihlsyep cluative. • Chemotherwaitphoy r,w ihtouste lecstugirevraeyn rdda itaiorne,m ains thteer tameonftc hoiicnte eh g remautl tiiytpo lfci acenrcesv etnh outghhe survivaflom rol semtvea etsltisaz secdna cermre aiqnui tleo w. oSptoimimes tic eviednce pwraests eetdnh caotm ibntaioonfcs eh motahpeyrr,a tthhearsn il neg agnethsa,v feam ro reefe fcotnc earittnu msoyres mtsB.u etv etnh epnr ospects froc ancceotrnrl ao rgel ooumneyls dsi ganoasnitdsr temaeanrtee a rly. • Emphassitsri elamli nosnt rtemaernatt thhearon np erventair oaeilnyt, poinetdt ob yt hmeo scto ntrovoeusrisnryeg-s acerhaerIrwts a.sp o inetdlpyu t thaatne ntdoc g iatrtesemo kiwnogu vlrdiut alellyi mtieln uang caannudcp­ er warodfs4 0 p ernctoe fc ancienAr me rimcaalne s. Fotrh wer itfeorui,rt eomfms a joirm oprtawnecrefe o rctohmifnrgo m thseme inro afe xperatdnst hneta iotnpo's sc iteinfwirecir ts: • Thev irtahle oorfcy a enrct,h per emsputitohnam to scta ncaerrseso me­ howc auds beyv iursecsa,m uend esrh aartpt abcyok n ree searwchohseer , coenntticoonv,ew reelbdly t hreh etoqruisectai"loD nov: i ursecsa ucsaeen rc ord oc anccearusvs riesu e?s"c uaesdp erhtahpsesah rpessiltne dg ebea att thgea etrhi.n g Icnerads ietneriensm ta inupaltitnhgbe o yd'ism miutnsyy staestm h e • frislti onfed eefnsaega niscta nc(eocrra nc-esircnsec onvennawtlii dosom reaminifsnel xibtlhea cta nciesarv aertioyf a tl eaI0s 0td iasseewsih touat prbobales ilnecg auosrep roblaesb incgulrewe a)sd emorntasetadn sde veral researpcoihneetdtr osp roimsienxgpm eerniitnst hfeei dl,t hekierpy r eimses beitnhgda ite sasieps ir mraliyar seposneb yt hheo sttod iesaseu-sgcia angents (aptohgnesr)a thtehrat nh eef foefct th pea thnosg etsheelmvaenstd,h atth e breakdaonwsdnh oruipon fgt ehb odys'o nylp atriaulnldyeo rosdit mmuyn it systaenmod f i thso rmosnyes tuenmd odublptyle adyr amartoilicenc s a ncer. • Thek eiy moprtaonfcn eu triitnpi rvoeenn tainncdga iunscga ncwears strebsyso endre e asrehcearn pdr oveodak mlosatsg rte acao tnrovaesrd siyd thaet taocnt kh veri atlh eyoo rfc ancTehre. sraemsee adrecrchieetrdh l ea ck 10 ofn urtititoarnmmagli n tnhaet' ismo enidcaslco hloasn dt latsltayt l·d: "Youdro ctkonros vw eyrl titalbeo nuutt rition." • Newsepraw preisrt fromc ititehosru ghotuhtec outnryr erptoed prers-esaumountiinng scosmaees t,h esya itdo," harass"m-efnrtom peopldee mandtiokn nogw w hyv iatmiBn11 ( aLetriisl eln)eo gtia ntl ih s counwthryhy u,m atsnet fsor L aterihlvaeen ot yeatut hboeerediwn,zh ym ore pepolaer neo ltoo kiinnogt t hteh ousoafnt deissm toniaanldcs lm aeidc ase hsiotrioefcs a ncceotrnrl bo yL aetrainlddee ,mn aditnokg n owwh yd epserate, treminlca ancpeairte nmtasyh aven oa cecstsoB 1i1nt hciosnu trayn di,n ­ stelatide,lr lahyav et o sgnoe iankogf tfoM exicoorW esGter manoyrs ome othceoru nwtherryte h ecyap nr octuhrseeu bstaannbdce te ra et.e d Thesfoeu irt eamrse moorft eh apna isgnsi moprtatnotc -heve ti mainB1 1 stofrroy,a, s t hree adweirnl olt teh,ee s seonftc heve ia tmiBnt a?pp oractho cancreerso tnts h eassems putnisoT:h eriesp orbablays ilnerg aelc ausoe f canceevre,tn h outghhee arrmeu lt"ipoglraienez rsw"h iccha n gterorif gf thastil necg ausCea.n ciesmr a ineftsedfr,is bty,a b reakdionw nbt odhye' s immnuologsiycsatalen mds,,e cobnydt ,ha eb seonfca ve i atlf oofdat coirn thneo rm"aclii vezdi"ld ieHtow. d ieitm npgieosn t hleta tearn,dh ow it maya fftehcftero memra,k sec ancmeorr,te h aann ythesilena,gs epicfviic­ taimn-diecefnicdyi sease. Int haet taocnt kh vei rtaholer oyf c ancaesar na corsse--tbhoeaxrpdl ­ana tioofnt hceua eso ft hder ded aiesasDer,P. au lH .B alcokf H aravrMde idcal Schotoollt dh7 e0 s cnicewer eirtasn eddi totrhsar tea srehci spr ieesce noguh nows ot ht"a cearitnclayu tmiuosbnte v oicaettd hp er eenstti ema ntdh reioes thaptr optohsaaetl c la ncidenurc ienvnget osp reatveiv aia rla citvatsieoenm unwraranatnewddti hosuutba snttlei viadnec.e" Ther eseaorncc haenrcv eiurrs easp ,rc aticpihniygsc isaadni t,h asti mply bceauvsriesu epsr oduicnte ehdt etsutb mea yb ei ncoulatientds i suaen d caucsaen rct eumodrosen so ptr otvihesi san taurcahla oifen v enitnls in vgi oragnsimtsh emseIlnevdeedhs,e.p o itneodu vti,u rsemsa yr esfuorlmtt m uors andc ertvariiunsw ehisc mha yc autsuem oorust stihdoeer a gnimsamy not cautsuem oirnns ta urhaols "tMso.r eoveevdrie,n ciesa ccmuulattioni gn ­ ditceta hatthv ea riionudsu caeginntgss u cahsc heimcarlasd,i aatnihdoo ­nr monecsa cna uasc ea nrcoeutsr aonrsmfatiinto hneo iwrnr ig"hh tea, dded. Byn om eawnasDs r B.al cokr a noyt hreeras rehcefror ntfionvrgti maiBnt ? orw erteh eiyna nwya yc ontneewdci htt hleta etrB.u tth epioirns ot fv iew opeendt hdeo ofrru thteotr h peos sbiiiltoyft heese sntlci oarrectonfev sis­ tmaiBnt ? therapy. DrE.r neLs.Wt y ndeprr,e siodfte hnAetm erni HceaaltFhon udatiino n NewY orrkpe,o rttehdat the ei r"sn icerasievnidge ntchean tu triptliaaoynns imoptratn rolaem"o ntgh een voinmrentfaalc twohrisca hr el iknedw tih cancdeeervl moepnWth.i dlarew ihnaegv fyi frreo omt hsecri etnswt hoih save concternaotnet dh veia rla nd-ootrhe enriv rnomenbtuantlo nidetaasrpye cts ofc ancidenurc thieo nrd,cei edi svoems eu ppforroMtm ic haingS taUtneie rv­ syi tphyilsoogainsdct h meisCtlf iofrWd. W elswchho,i, nd siucssinnegw 11