09/28/2022 Kit Components Product code Description N8140504 Nexion Sloution Kit Components: N8145051 NexION Setup Solution N8145050 NexION Rinse Solution N8145055 NexION STD/DRC Mode Detection Limit Blank Solution N8145056 NexION STD/DRC Mode Detection Limit Standard Solution N8145059 NexION Dual Detector Calibration Solution N8145054 NexION Cell Stability Solution N8145057 NEXION KED MODE DETECTION LIMIT BLANK SOLUTION N8145058 NexION KED Mode Detection Limit Standard Solution N8145052 NexION KED Mode Setup Solution Page 1/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 * 1 Identification ∙ Product identifier ∙ Trade name:NexION Setup Solution ∙ Article numberN8145051 ∙ Application of the substance / the mixtureLaboratory chemicals ∙ Details of the supplier of the safety data sheet ∙ Manufacturer/Supplier: PerkinElmer, Inc. 710 Bridgeport Avenue Shelton, Connecticut 06484 USA [email protected] 203-925-4600 ∙ Emergency telephone number: CHEMTREC (within US) 800-424-9300 CHEMTREC (from outside US) +1 703-527-3887 (call collect) CHEMTREC (within AU) +(61)-290372994 * 2 Hazard(s) identification ∙ Classification of the substance or mixture Skull and crossbones Acute Toxicity - Inhalation 3 H331Toxic if inhaled. Skin Irrititation 2 H315Causes skin irritation. Eye Irritation 2A H319Causes serious eye irritation. ∙ Label elements ∙ GHS label elementsThe product is classified and labeled according to the Globally Harmonized System (GHS). ∙ Hazard pictogramsGHS06, GHS07 ∙ Signal wordDanger ∙ Hazard-determining components of labeling: Nitric Acid ∙ Hazard statements H331Toxic if inhaled. H315Causes skin irritation. H319Causes serious eye irritation. ∙ Precautionary statements P261 Avoid breathing dust/fume/gas/mist/vapors/spray P264 Wash thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves / eye protection / face protection. P302+P352 If on skin: Wash with plenty of water. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. (Contd. on page 2) USA 54.2.3 Page 2/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 1) P311 Call a poison center/doctor. P305+P351+P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P321 Specific treatment (see on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P332+P313 If skin irritation occurs: Get medical advice/attention. P337+P313 If eye irritation persists: Get medical advice/attention. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. ∙ Classification system: ∙ NFPA ratings (scale 0 - 4) Health = 2 0 Fire = 0 2 0 Reactivity = 0 ∙ HMIS-ratings (scale 0 - 4) HEALTH 2 Health = 2 FIRE 0 Fire = 0 REACTIVITY 0 Reactivity = 0 ∙ Other hazards The product does not contain any organic halogen compounds (AOX), nitrates, heavy metal compounds or formaldehydes. ∙ Results of PBT and vPvB assessment ∙ PBT:Not applicable. ∙ vPvB:Not applicable. * 3 Composition/information on ingredients ∙ Chemical characterization: Mixtures ∙ Description:Mixture of the substances listed below with nonhazardous additions. ∙ Hazardous components: 7697-37-2 Nitric Acid 1.0% ∙ Additional Components 7732-18-5 Water 98.9992% 7439-89-6 iron 0.0001% 7439-92-1 lead 0.0001% 7439-93-2 lithium 0.0001% 7439-95-4 magnesium 0.0001% 7440-41-7 beryllium 0.0001% 7440-45-1 cerium 0.0001% 7440-61-1 uranium 0.0001% (Contd. on page 3) USA 54.2.3 Page 3/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 2) 7440-74-6 Indium 0.0001% * 4 First-aid measures ∙ Description of first aid measures ∙ General information: Immediately remove any clothing soiled by the product. Remove breathing apparatus only after contaminated clothing have been completely removed. In case of irregular breathing or respiratory arrest provide artificial respiration. ∙ After inhalation: Supply fresh air or oxygen; call for doctor. In case of unconsciousness place patient stably in side position for transportation. ∙ After skin contact:Immediately wash with water and soap and rinse thoroughly. ∙ After eye contact: Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor. ∙ After swallowing:If symptoms persist consult doctor. ∙ Most important symptoms and effects, both acute and delayedNo further relevant information available. ∙ Indication of any immediate medical attention and special treatment needed No further relevant information available. * 5 Fire-fighting measures ∙ Extinguishing media ∙ Suitable extinguishing agents:Use fire fighting measures that suit the environment. ∙ Special hazards arising from the substance or mixtureNo further relevant information available. ∙ Advice for firefighters ∙ Protective equipment:Mouth respiratory protective device. * 6 Accidental release measures ∙ Personal precautions, protective equipment and emergency proceduresNot required. ∙ Environmental precautions: Inform respective authorities in case of seepage into water course or sewage system. Dilute with plenty of water. ∙ Methods and material for containment and cleaning up: Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Dispose contaminated material as waste according to item 13. Ensure adequate ventilation. ∙ Reference to other sections See Section 7 for information on safe handling. See Section 8 for information on personal protection equipment. See Section 13 for disposal information. ∙ Protective Action Criteria for Chemicals ∙ PAC-1: 7697-37-2 Nitric Acid 0.16 ppm 7439-89-6 iron 3.2 mg/m³ (Contd. on page 4) USA 54.2.3 Page 4/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 3) 7439-92-1 lead 0.15 mg/m³ 7439-93-2 lithium 3.3 mg/m³ 7439-95-4 magnesium 18 mg/m³ 7440-41-7 beryllium 0.0023 mg/m³ 7440-45-1 cerium 30 mg/m³ 7440-61-1 uranium 0.6 mg/m³ 7440-74-6 Indium 0.3 mg/m³ ∙ PAC-2: 7697-37-2 Nitric Acid 24 ppm 7439-89-6 iron 35 mg/m³ 7439-92-1 lead 120 mg/m³ 7439-93-2 lithium 36 mg/m³ 7439-95-4 magnesium 200 mg/m³ 7440-41-7 beryllium 0.025 mg/m³ 7440-45-1 cerium 330 mg/m³ 7440-61-1 uranium 5 mg/m³ 7440-74-6 Indium 3.3 mg/m³ ∙ PAC-3: 7697-37-2 Nitric Acid 92 ppm 7439-89-6 iron 150 mg/m³ 7439-92-1 lead 700 mg/m³ 7439-93-2 lithium 220 mg/m³ 7439-95-4 magnesium 1,200 mg/m³ 7440-41-7 beryllium 0.1 mg/m³ 7440-45-1 cerium 2,000 mg/m³ 7440-61-1 uranium 30 mg/m³ 7440-74-6 Indium 20 mg/m³ * 7 Handling and storage ∙ Handling: ∙ Precautions for safe handling Ensure good ventilation/exhaustion at the workplace. Open and handle receptacle with care. Prevent formation of aerosols. ∙ Information about protection against explosions and fires:Keep respiratory protective device available. ∙ Conditions for safe storage, including any incompatibilities ∙ Storage: ∙ Requirements to be met by storerooms and receptacles:No special requirements. ∙ Information about storage in one common storage facility:Not required. ∙ Further information about storage conditions:Keep receptacle tightly sealed. (Contd. on page 5) USA 54.2.3 Page 5/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 4) ∙ Specific end use(s)No further relevant information available. * 8 Exposure controls/personal protection ∙ Additional information about design of technical systems:No further data; see item 7. ∙ Control parameters ∙ Components with limit values that require monitoring at the workplace: 7697-37-2Nitric Acid PEL Long-term value: 5 mg/m³, 2 ppm REL Short-term value: 10 mg/m³, 4 ppm Long-term value: 5 mg/m³, 2 ppm TLV Short-term value: (4) NIC-0.025* ppm Long-term value: (2) ppm *inh. fraction + vapor ∙ Additional information:The lists that were valid during the creation were used as basis. ∙ Exposure controls ∙ Personal protective equipment: ∙ General protective and hygienic measures: Keep away from foodstuffs, beverages and feed. Immediately remove all soiled and contaminated clothing. Wash hands before breaks and at the end of work. Store protective clothing separately. Avoid contact with the eyes and skin. ∙ Breathing equipment: In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air. ∙ Protection of hands: Protective gloves The glove material has to be impermeable and resistant to the product/ the substance/ the preparation. Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation ∙ Material of gloves The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application. ∙ Penetration time of glove material The exact break trough time has to be found out by the manufacturer of the protective gloves and has to be observed. (Contd. on page 6) USA 54.2.3 Page 6/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 5) ∙ Eye protection: Tightly sealed goggles or safety glasses * 9 Physical and chemical properties ∙ Information on basic physical and chemical properties ∙ General Information ∙ Appearance: Form: Liquid Color: Not determined. ∙ Odor: Characteristic ∙ Odor threshold: Not determined. ∙ pH-value: Not determined. ∙ Change in condition Melting point/Melting range: 0 °C (32 °F) Boiling point/Boiling range: 100 °C (212 °F) ∙ Flash point: Not applicable. ∙ Flammability (solid, gaseous): Not applicable. ∙ Decomposition temperature: Not determined. ∙ Auto igniting: Product is not selfigniting. ∙ Danger of explosion: Product does not present an explosion hazard. Not determined. ∙ Explosion limits: Lower: Not determined. Upper: Not determined. ∙ Vapor pressure at 20 °C (68 °F): 23 hPa (17.3 mm Hg) ∙ Density: Not determined. ∙ Relative density Not determined. ∙ Vapor density Not determined. ∙ Evaporation rate Not determined. ∙ Solubility in / Miscibility with Water: Fully miscible. ∙ Partition coefficient (n-octanol/water):Not determined. ∙ Viscosity: Dynamic: Not determined. Kinematic: Not determined. ∙ Solvent content: Water: 99.0 % (Contd. on page 7) USA 54.2.3 Page 7/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 6) VOC content: 0.00 % ∙ Other information No further relevant information available. * 10Stability and reactivity ∙ ReactivityNo further relevant information available. ∙ Chemical stability ∙ Thermal decomposition / conditions to be avoided:No decomposition if used according to specifications. ∙ Possibility of hazardous reactionsNo dangerous reactions known. ∙ Conditions to avoidNo further relevant information available. ∙ Incompatible materials:No further relevant information available. ∙ Hazardous decomposition products:No dangerous decomposition products known. * 11Toxicological information ∙ Information on toxicological effects ∙ Acute toxicity: ∙ Primary irritant effect: ∙ on the skin:Irritant to skin and mucous membranes. ∙ on the eye:Irritating effect. ∙ Sensitization:No sensitizing effects known. ∙ Additional toxicological information: The product shows the following dangers according to internally approved calculation methods for preparations: Toxic Irritant ∙ Carcinogenic categories ∙ IARC (International Agency for Research on Cancer) 7439-92-1 lead 2B 7440-41-7 beryllium 1 ∙ NTP (National Toxicology Program) 7439-92-1 lead R 7440-41-7 beryllium K ∙ OSHA-Ca (Occupational Safety & Health Administration) None of the ingredients is listed. * 12Ecological information ∙ Toxicity ∙ Aquatic toxicity:No further relevant information available. ∙ Persistence and degradabilityNo further relevant information available. ∙ Behavior in environmental systems: ∙ Bioaccumulative potentialNo further relevant information available. ∙ Mobility in soilNo further relevant information available. (Contd. on page 8) USA 54.2.3 Page 8/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 7) ∙ Additional ecological information: ∙ General notes: Do not allow product to reach ground water, water course or sewage system. Danger to drinking water if even small quantities leak into the ground. ∙ Results of PBT and vPvB assessment ∙ PBT:Not applicable. ∙ vPvB:Not applicable. ∙ Other adverse effectsNo further relevant information available. * 13Disposal considerations ∙ Waste treatment methods ∙ Recommendation: Dispose of container and materials in accordance with local, regional and national regulations. ∙ Uncleaned packagings: ∙ Recommendation:Disposal must be made according to official regulations. ∙ Recommended cleansing agent:Water, if necessary with cleansing agents. * 14Transport information ∙ UN-Number ∙ DOT, ADR, IMDG, IATA UN3264 ∙ UN proper shipping name ∙ DOT Corrosive liquid, acidic, inorganic, n.o.s. (Nitric Acid) ∙ ADR 3264 CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (Nitric Acid) ∙ IMDG, IATA CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (Nitric Acid) ∙ Transport hazard class(es) ∙ DOT ∙ Class 8 Corrosive substances ∙ Label 8 ∙ ADR ∙ Class 8 (C1) Corrosive substances (Contd. on page 9) USA 54.2.3 Page 9/11 Safety Data Sheet acc. to OSHA HCS Printing date 09/28/2022 Review date 09/28/2022 Trade name:NexION Setup Solution (Contd. of page 8) ∙ Label 8 ∙ IMDG, IATA ∙ Class 8 Corrosive substances ∙ Label 8 ∙ Packing group ∙ DOT, ADR, IMDG, IATA III ∙ Environmental hazards: ∙ Marine pollutant: No ∙ Special precautions for user Warning: Corrosive substances ∙ Hazard identification number (Kemler code):80 ∙ EMS Number: F-A,S-B ∙ Segregation groups Acids ∙ Stowage Category A ∙ Stowage Code SW2 Clear of living quarters. ∙ Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable. ∙ Transport/Additional information: ∙ DOT ∙ Quantity limitations On passenger aircraft/rail: 5 L On cargo aircraft only: 60 L ∙ ADR ∙ Excepted quantities (EQ) Code: E1 Maximum net quantity per inner packaging: 30 ml Maximum net quantity per outer packaging: 1000 ml ∙ IMDG ∙ Limited quantities (LQ) 5L ∙ Excepted quantities (EQ) Code: E1 Maximum net quantity per inner packaging: 30 ml Maximum net quantity per outer packaging: 1000 ml ∙ UN "Model Regulation": UN 3264 CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (NITRIC ACID), 8, III * 15Regulatory information ∙ Safety, health and environmental regulations/legislation specific for the substance or mixture 7732-18-5 Water 98.9992% 7697-37-2 Nitric Acid 1.0% 7439-89-6 iron 0.0001% (Contd. on page 10) USA 54.2.3