JOURNAL OF PATHOLOGY, VOL. 164: iv—vi (1991) CONTENTS Volume 164, Issue Nos 1-4, 1991 JOURNAL OF PATHOLOGY Issue No. 1 MAY 1991 Review Article The Human Carotid Body in Health and Disease: D. HEATH Original Papers Morphological Evidence That A-CAM is a Major Intercellular Adhesion Molecule in Human Kidney: L. R. BIDDLESTONE and S. FLEMING Simultaneous Detection of Fluorescent in situ Hybridization and in vivo Incorporated Brinda UHuma n Bladder Tumour: H. VAN DEKKEN, E.W. SCHERVISH, J. G. PIZZOLO, W. R. FAIR and M.R.MELAMED . : Malignant Peripheral Nerve Sheath Tumour with Annulate Lamellae Mimicking PF leo- morphic Malignant Fibrous Histiocytoma: J.R.GOODLAD andC.D.M.FLETCHER . Late BCNU Lung: a Light and Ultrastructural Study on the Delayed Effect of BCNU on the Lung Parenchyma: P. S. HASELTON, B. R. O'DRISCOLL, P. LYNCH, A. WEBSTER, S. J. KALRA, H. R. GATTAMANEINI, A. A.W OODCOCK and L. W. POULTER Localization of Immunoglobulin Light Chain mRNA Expression in Hodgkin's Disease ™ in situ Hybridization: A. K. RUPRAI, J. H. PRINGLE, C.A. ANGEL, C.N. KIND and I. LAUDER. Measurement of the Tissue Distribution of Immunoperoxidase Staining with Polyclonal Anti-BCG Serum in Lung Granulomata of Mice Infected with Mycobacterium tuberculosis: J.M .ORRELL, S. J. BRETT, J. IVANYI, G. COGHILL, A. GRANanTd J. S. BECK An Assessment of MAC 387 Antibody as a Diagnostically Useful Marker of L1 — Antigen Expression by Lung Tumours: F.G. MAYALL and A. R. GIBBS. Investigation of a Quantitative Post-hybridization Signal Amplification ene for mRNA- ae in situ ieeramuuall J. A. HOYLAND and A. J. FREEMONT . Control of Differentiation in a Rectal Adenocarcinoma Cell Line: the Role of Diffusable and Cell-associated Factors: R. DEL BUONO, M. PIGNATELLI and P. A. HALL Detection of mRNA for Ribosomal Phosphoprotein P2 in Normal Colon and Colonic Tumours by in situ serials R. HARVIE, P. ELVIN, C. McARDLE, J. E.N. MORTEN and A. M. McNICOL ‘ p53 Expression in Human Breast Cancer Related to Survival and Seeenns Factors: an Iimmunohistochemical Study: J. L.O STROWSKI, A. SAWAN, L. HENRY, C. WRIGHT, J. A. HENRY, C. HENNESSY, T. J. W. LENNARD, B. ANGUS and C. H. W. HORNE A Histochemical and Immunocytochemical Study of Hepatic Copper and Metallo- thionein in the Pre- and Post-natal Rat: M. E. ELMES, S. HAYWOOD and B. JASANI. Book Reviews . Announcement. Issue No. 2 JUNE 1991 C. L. Oakley Lecture (1991) Cell Adhesion and Epithelial Differentiation: S. FLEMING Review Article — Chromosome Pathology DNA Fingerprinting: P.G. DEBENHAM JOURNAL OF PATHOLOGY, VOL. 164: iv—vi (1991) CONTENTS Volume 164, Issue Nos 1-4, 1991 JOURNAL OF PATHOLOGY Issue No. 1 MAY 1991 Review Article The Human Carotid Body in Health and Disease: D. HEATH Original Papers Morphological Evidence That A-CAM is a Major Intercellular Adhesion Molecule in Human Kidney: L. R. BIDDLESTONE and S. FLEMING Simultaneous Detection of Fluorescent in situ Hybridization and in vivo Incorporated Brinda UHuma n Bladder Tumour: H. VAN DEKKEN, E.W. SCHERVISH, J. G. PIZZOLO, W. R. FAIR and M.R.MELAMED . : Malignant Peripheral Nerve Sheath Tumour with Annulate Lamellae Mimicking PF leo- morphic Malignant Fibrous Histiocytoma: J.R.GOODLAD andC.D.M.FLETCHER . Late BCNU Lung: a Light and Ultrastructural Study on the Delayed Effect of BCNU on the Lung Parenchyma: P. S. HASELTON, B. R. O'DRISCOLL, P. LYNCH, A. WEBSTER, S. J. KALRA, H. R. GATTAMANEINI, A. A.W OODCOCK and L. W. POULTER Localization of Immunoglobulin Light Chain mRNA Expression in Hodgkin's Disease ™ in situ Hybridization: A. K. RUPRAI, J. H. PRINGLE, C.A. ANGEL, C.N. KIND and I. LAUDER. Measurement of the Tissue Distribution of Immunoperoxidase Staining with Polyclonal Anti-BCG Serum in Lung Granulomata of Mice Infected with Mycobacterium tuberculosis: J.M .ORRELL, S. J. BRETT, J. IVANYI, G. COGHILL, A. GRANanTd J. S. BECK An Assessment of MAC 387 Antibody as a Diagnostically Useful Marker of L1 — Antigen Expression by Lung Tumours: F.G. MAYALL and A. R. GIBBS. Investigation of a Quantitative Post-hybridization Signal Amplification ene for mRNA- ae in situ ieeramuuall J. A. HOYLAND and A. J. FREEMONT . Control of Differentiation in a Rectal Adenocarcinoma Cell Line: the Role of Diffusable and Cell-associated Factors: R. DEL BUONO, M. PIGNATELLI and P. A. HALL Detection of mRNA for Ribosomal Phosphoprotein P2 in Normal Colon and Colonic Tumours by in situ serials R. HARVIE, P. ELVIN, C. McARDLE, J. E.N. MORTEN and A. M. McNICOL ‘ p53 Expression in Human Breast Cancer Related to Survival and Seeenns Factors: an Iimmunohistochemical Study: J. L.O STROWSKI, A. SAWAN, L. HENRY, C. WRIGHT, J. A. HENRY, C. HENNESSY, T. J. W. LENNARD, B. ANGUS and C. H. W. HORNE A Histochemical and Immunocytochemical Study of Hepatic Copper and Metallo- thionein in the Pre- and Post-natal Rat: M. E. ELMES, S. HAYWOOD and B. JASANI. Book Reviews . Announcement. Issue No. 2 JUNE 1991 C. L. Oakley Lecture (1991) Cell Adhesion and Epithelial Differentiation: S. FLEMING Review Article — Chromosome Pathology DNA Fingerprinting: P.G. DEBENHAM VOLUME CONTENTS Original Papers Gastrointestinal Stromal Tumours: Correlation of Immunophenotype with Clinico- pathological Features: P.L. NEWMAN, C. WADDEN and C. D. M. FLETCHER Immunohistological Analysis of the Immunoreactivity of Normal Lymphoid Cells and Lymphomas with the Monoclonal Antibody OPD4: J. O'GRADY, A. J. BLAIKIE, S. E. HOWIE, D. M. SALTER and A. S. KRAJEWSKI ' In Vitro Modulation of Cellular Localization of Milk Fat Globule Membrane iennmens in Human Breast Carcinomas: D. CORCORAN, J. L. JONES and R.A. WALKER . ; Potential Antigen-Presenting Cells in Normal Extraocular Muscles Demonstrated with Double Immunoenzyme Staining: E. D. SCHMIDT, P. K. DAS, R. VAN DER GAAG, A. J. TIGGES, C. M. VAN DER LOOS and L. KOORNNEEF. Expression of Different Cytokeratin Subclasses in Human Chordoma: K. HEIKINHEIMO, S. PERSSON, L.-G. KINDBLOM, P. R. MORGAN and| . VIRTANEN Adhesion of Normal andu eeene oo Cells to Fibroblasts: A. S. JACK and K. J. CHAPMAN . Intercellular Contacts in the Media of the Thoracic Aorta of Rat Fetuses Treated with B-Aminopropionitrile: J. A.S OSA-MELGAREJO andC. L. BERRY . Cellular Sources of Matrix Proteins in Experimentally Induced Cholestatic Rat Liver: G. ABDEL-AZIZ, P.-Y. RESCAN, B. CLEMENT, G. LEBEAU, M. RISSEL, J.-A. GRIMAUD, J.-P. CAMPION and A. GUILLOUZO : Pneumocystis Carinii Pneumonia in Simian Immunodeficiency Virus Infection: Immunohistological and Scanning and Transmission Electron Microscopical Studies: A. BASKERVILLE, A. B. DOWSETT, R. W. COOK, M. J. DENNIS, M. P. CRANAGE and P. J. GREENAWAY. , ; : ‘ ‘ : : Book Reviews . issue No. 3 JULY 1991 Editorials Wegener's Granulumatosis, ANCA, and Microscopic Polyarteritis: B. J.A DDIS Identification of HPV: /n Situ a or hese eaapraadihC hain Reaction? M. J. ARENDS ‘ : ; : é 2 ; Review Article The Formation and Fate of Glomerular |mmune Complex Deposits: P.N. FURNESS Original Papers The Latent Membrane Protein-1 in Epstein-Barr Virus-Transformed Lymphoblastoid Cells is Found with Ubiquitin-Protein Conjugates and Heat-Shock Protein 70 in Lyso- somes Oriented Around the Microtubule Organizing Centre: L. LASZLO, J. TUCKWELL, T. SELF, J. LOWE, M. LANDON, S. SMITH, J. N. HAWTHORNE and R. J. MAYER A Series of 14 New Monoclonal Antibodies to Keratins: Characterization and Value in Diagnostic Histopathology: J. BARTEK, B. VOJTESEK, Z. STASKOVA, J. BARTKOVA, Z. KEREKES, A. REJTHAR and J. KOVARIK. An Outbreak of Aflatoxicosis and Boric Acid Poisoning in en A Clinicopatho- logical Study: T.-C. CHAO, S. M.M AXWELL and S.-Y. WONG The Topographical and Age Distributions of Neuroendocrine Cells in the Normal Human Appendix: P. A. V. SHAW : The Vascularity of Primary Cutaneous Melanoma: M. E. FALLOWFIELD and M. G. COOK Image Analysis Quantification of Peptide-lmmunoreactive Nerves inthe Skin of Patients with Raynaud’s Phenomenon and Systemic Sclerosis: G. TERENGHI, C. B. BUNKER, Y.-F. LIU, D. R. SPRINGALL, T. COWEN, P.M. DOWD and J.M. POLAK . Immunocytochemical Observations on Macrophage Populations in Normal Fetal and Adult Human Liver: K. A. BARDADIN, P. J. SCHEUER, A. PECZEK and J. WEJMAN Thyroglobulin in Human Thyroid Follicles with Acid Mucin: H.R. HARACH VOLUME CONTENTS Histopathological Studies on the Local Reactions Induced by Complete Freund's Adjuvant (CFA), Bacterial Lipopolysaccharide (LPS), and Synthetic Lipopeptide (P,;C) Conjugates: F. WIEDEMANN, R. LINK, K. PUMPE, U. JACOBSHAGEN, H. E. SCHAEFER, K.-H. WIESMULLER, R.-P. HUMMEL, G. JUNG, W. BESSLER andT . BOLTZ Phenotypic Modulation in Lipocytes in Experimental Liver Fibrosis: Y. TANAKA, T. NOUCHI, M. YAMANE, T. IRIE, H. MIYAKAWA, C. SATO and F. MARUMO . Teaching Column An Opinion: The Role of the intercalated Pathology Degree: P. A. WRIGHT Book Reviews . Announcement . Issue No. 4 AUGUST 1991 Editorial Koch’s Postulates Revisited: P. A. HALL and N. R. LEMOINE Original Papers Immunohistochemical Detection of the Epidermal Growth Factor Receptor in Paraffin- Embedded Human Tissues: W. J. GULLICK, C. M. HUGHES, K. MELLON, D. E. NEAL and N. R. LEMOINE : ‘ Persistence of a Virus in Reed-Sternberg Cells ee the Course of Hodgkin’s Disease: P. J.C OATES, G. SLAVIN and A. J. DDARDENNE Immunohistochemical and Quantitative Study of Interstitial and Intratubular Leydig Cells in Normal Men, Cryptorchidism, and Klinefelter’s Syndrome: J. REGADERA, J. CODESAL, R. PANIAGUA, P. GONZALEZ-PERAMATO and M. NISTAL. Necrotizing Myopathy in Critically-ill Patients: T. R. HELLIWELL, J. H. COAKLEY, A. J. M. WAGENMAKERS, R. D. GRIFFITHS, |. T. CAMPBELL, C. J. GREEN, P. McCLELLAND and J. M. BONE infantile Desmoid-Type Fibromatosis. a Features Correlate With Bio- logical Behaviour: D. SCHMIDT, P. KLINGE, |. LEUSCHNER and D. HARMS. Phenotypic Analysis of Malignant Lymphoma in Simian Immunodeficiency Virus Infec- tion using Anti-human Antibodies: A. D. RAMSAY, J. GIDDINGS, A. BASKERVILLE and M.P.CRANAGE . ; Irreversible Damage to the Medullary interstitium in on pete Nephropathy in F344 Rats: J. H. BURRELL, J. L.C. YONG and G. J.M ACDONALD Critical Summaries Dermatopathology: D.N.SLATER Letters to the Editor Iimmunohistochemical Determination of CD23 Expression in Hodgkin's Disease Using Paraffin Sections: R. F. JARRETT, A. ARMSTRONG, B.S. WILKINS and D.B. JONES . 345 Appendiceal Carcinoids and Pulmonary Tumourlets: F.PANSERA. 346 Synopses of Papers Synopses of Papers Presented at the 163rd we of the a a of Great Britain and Ireland . ; : . 347A Volume Contents iii Key Word Index. vii Author Index