CONTENTS OF VOLUME 34 Number | Molecules in focus Roy A. Black l Tumor necrosis factor-% converting enzyme Natalie A. Little and 6 p63 Aart G. Jochemsen Review Laura Polo, Giuliana Valduga, 10 Low-density lipoprotein receptors in the uptake of tumour photo- Giulio Jori and Elena Reddi sensitizers by human and rat transformed fibroblasts General papers Zofia Galewska, Lech Romanowicz, 24 Preeclampsia-associated decrease of potential collagenolytic and Edward Bankowski and gelatinolytic activities in the wall of the umbilical cord vein Stefan Jaworski Nina Petrova, Liliana Gigova and ki Dimerization of Rhizobium meliloti NifH protein in Saccharomyces Pencho Venkov cerevisiae cells requires simultaneous expression of NifM protein Keng Meng Khoo and Identification and characterization of nuclear CD38 in the rat spleen Chan Fong Chang P. Anne Underwood, 55 Rate of endothelial expansion is controlled by cell:cell adhesion Penny A. Bean and Jennifer R. Gamble Mohammad D. Bazzi, Nayyar Rabbani Inhibition of camel lens C-crystallin by aspirin and aspirin-like and Ali S. Duhaiman analgesics Chao Cheng, Kang Ying, Ming Xu, 78 Cloning and characterization of a novel human transcription factor Wei Zhao, Zongxiang Zhou, AP-28 like gene (TFAP2BL1) Yan Huang, Wei Wang, Jian Xu, Li Zheng, Yi Xie and Yumin Mao Evdokia A. Pasheva, Iva Ugrinova, 87 The binding affinity of HMGI1 protein to DNA modified by cis- Nadejda C. Spassovaska and platin and its analogs correlates with their antitumor activity Iliya G. Pashev Wei Wang, Yan Huang, 93 Identification and characterization of AGTRAP, a human homolog Zongxiang Zhou, Rong Tang, of murine Angiotensim II Receptor-Associated Protein (Agtrap) Wei Zhao, Li Zheng, Ming Xu, Chao Chang, Shaohua Gu, Kang Ying, Yi Xie and Yumin Mao Number 2 Molecules in focus Nghia T.V. Lee and Des R. Richardson 103.‘ Ferroportinl: a new iron export molecule? Short communication Xiaohua Ni, Yushu Ma, 109 Cloning and characterization of a novel human pantothenate kinase Haipeng Cheng, Min Jiang, gene Kang Ying, Yi Xie and Yumin Mao Review Christian Conrad and Reinhard Rauhut 116 Ribonuclease III: new sense from nuisance General papers A. Ostuni, M.D. Lograno, Novel properties of peptides derived from the sequence coded by A.R. Gasbarro, F. Bisaccia exon 26A of human elastin and A.M. Tamburro Wen-Bin Ou, Yong-Doo Park and Effect of osmolytes as folding aids on creatine kinase refolding Hai-Meng Zhou pathway Kamal Datta, Preeti Babbar, 148 p53 dependent apoptosis in glioma cell lines in response to hydro- Tapasya Srivastava, Subrata Sinha and gen peroxide induced oxidative stress Parthaprasad Chattopadhyay David R. Jones, Clive S. D’Santos, T lymphocyte nuclear diacyloglycerol is derived from both de novo Isabel Mérida and Nullin Divecha synthesis and phosphoinositide hydrolysis Mehran Miroliaei and 169 Effect of organic solvents on stability and activity of two related Mohsen Nemat-Gorgani alcohol dehydrogenases: a comparative study Allen J. Bailey, Trevor J. Sims and 176 Phynotypic expression of osteoblast collagen in osteoarthritic bone: Lynda Knott production of type I homotrimer M. Carmen Hidalgo, Antonia Expésito, 183 Oxidative stress generated by dietary Zn-deiciency: studies in rain- José M. Palma and Manuel de la Higuera bow trout (Oncorhynchus mykiss) Kenneth R. Cutroneo 194 Relationship between glucocorticoid-mediated early decrease of pro- tein synthesis and the steady state decreases of glucocorticoid recep- tor and TGR-f activator protein Ji Young Son, Sook Shin, 204 Purification of soluble acetylcholinesterase from Japanese quail Kwang Ho Choi and In Kook Park brain by affinity chromatography Number 3 Molecules in focus Judith M. Greer and Myelin proteolipid protein—the first 50 years Marjorie B. Lees Maria L. Tomaro and Bilirubin: its role in cytoprotection against oxidative stress Alcira M. del C. Batlle Review Patrizia Agostinis, Hypericin in cancer treatment: more light on the way Annelies Vantieghem, Wilfried Merlevede and Peter A.M. de Witte General papers Eduardo Mirpuri, Altered liver gene expression in CCly-cirrhotic rats is partially nor- Elena R. Garcia-Trevijano, malized by insulin-like growth factor-I Inma Castilla-Cortazar, Carmen Berasain, Jorge Quiroga, Carlos Rodriguez-Ortigosa, José M. Mato, Jestis Prieto and Matias A. Avila Nazmi Ozer, Cumhur Bilgi and 3 Dog liver glucose-6-phosphate dehydrogenase: purification and I. Hamdi Ogiis kinetic properties Wen-jun He, Shuang Tang and 3. In vitro interaction of eukaryotic elongation factor 2 with synthetic Wang-yi Liu oligoribonucleotide that mimics GTPase domain of rat 28S ribo- somal RNA Eduardo Garcia-Fuentes, Dipyridamole prevents the coconut oil-induced hypercholesterole- Almudena Gil-Villarino, mia. A study on lipid plasma and lipoprotein composition M®* Flor Zafra and Eduardo Garcia-Peregrin Aleksandra Cvoro and Hyperthermic stress stimulates the association of both constitutive Gordana Mati¢ and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor Alike W. van der Velden, Ribosomal scanning on the highly structured insulin-like growth Kirsten van Nierop, factor II-leader | Harry O. Voorma and Adri A.M. Thomas Thi-Ping Feng and A graphic representation of protein sequence and predicting the Chun-Ting Zhang subcellular locations of prokaryotic proteins Number 4 Molecules in focus Jonas Heilskov Graversen, CD163: a signal receptor scavenging haptoglobin—hemoglobin com- Mette Madsen and Sgren K. Moestrup plexes from plasma Mare Payton and Steve Coats Cyclin E2, the cycle continues Haitham T. Idriss, Osama Al-Assar DNA polymerase 8 and Samuel H. Wilson Short communications Zhen Zhang, ChaoQun Wu, 325 Cloning and characterization of ARHGAP12, a novel human Shu Wang, Wei Huang, rhoGAP gene ZongXiang Zhou, Kang Ying, Yi Xie and YuMin Mao Lorena G. Fenoll, 33 Michaelis constants of mushroom tyrosinase with respect to oxygen José Neptuno Rodriguez-Lopez, in the presence of monophenols and diphenols Francisco Garcia-Molina, Francisco Garcia-Canovas and José Tudela General papers Noxolo Mkwetshana, Ryno J. Naudé, 337 The purification and characterisation of m-calpain from ostrich brain Willem Oelofsen, Koji Muramoto and Takako Naganuma Miguel Martin, Manuel Macias, 348 Melatonin increases the activity of the oxidative phosphorylation Josefa Leon, Germaine Escames, enzymes and the production of ATP in rat brain and liver mitochon- Houda Khaldy and dria Darios Acuna-Castroviejo M.C. Manjabacas, E. Valero, 358 Linear mixed irreversible inhibition of the autocatalytic activation of M. Moreno-Conesa, M. Garcia-Moreno, zymogens. Kinetic analysis checked by simulated progress curves M. Molina-Alarcon and R. Varon Andreas Artl, Gunther Marsche, Impaired capacity of acute-phase high density lipoprotein particles Pirkko Pussinen, Gabriele Knipping, to deliver cholesteryl ester to the human HUH-7 hepatoma cell line Wolfgang Sattler and Ernst Malle Eric S. Hungness, Timothy A. Pritts, 382 IL-1 activates C/EBP-8 and 6 in human enterocytes through a Guang-Ju Luo, Dan D. Hershko, mitogen-activated protein kinase signaling pathway Bruce W. Robb and Per-Olof Hasselgren Rong-Gui Hu, Qi-Wei Zhai, 396 Bioactivities of ricin retained and its immunoreactivity to anti-ricin Wen-Jun He, Ling Mei and polyclonal antibodies alleviated through pegylation Wang-Yi Liu C. Cobaleda, I. Munoz-Barroso, 403 Fusogenic activity of reconstituted newcastle disease virus envel- A. Sagrera and E. Villar opes: a role for the hemagglutinin-neuraminidase protein in the fusion process Joyce Dijkmans, Jean Xu, 414 Characterization of platelet-derived growth factor-C (PDGF-C): Stefan Masure, Sridevi Dhanaraj, expression in normal and tumor cells, biological activity and chro- Anna Gosiewska, Jeff Geesin, mosomal localization Jorg Sprengel, Sarah Harris, Peter Verhasselt, Robert Gordon and Jeff Yon Number 5 Molecules in focus Steve E. Jones and Catherine Jomary Clusterin John H. Kehrl and Srikumar Sinnarajah RGS2: a multifunctional regulator of G-protein signaling Reviews José M. Matés, Cristina Pérez-Gomez, 439 Glutamine and its relationship with intracellular redox status, Ignacio Nunez de Castro, Maite Asenjo oxidative stress and cell proliferation/death and Javier Marquez Martin J.O. Francis, Rita L. Lees, 459 ATPase pumps in osteoclasts and osteoblasts Elisa Trujillo, Pablo Martin-Vasallo, Johan N.M. Heersche and Ali Mobasheri VI General papers Guido A.F. Van Dessel, Prenylcysteine carboxymethyltransferase type III activity is Hilde M. De Busser and decreased in retinoic acid-treated SH-SYSY neuroblastoma cells Albert R. Lagrou Del L.C. Sim, W.M. Yeo and The novel human HUEL (C4orf1) protein shares homology with the Vincent T.K. Chow DNA-binding domain of the XPA DNA repair protein and displays nuclear translocation in a cell cycle-dependent manner Adeeb A. Girjes, Dahlia Keriakous, Cloning of a differentially expressed tropomyosin isoform from Gillian W. Cockerill, Ilan P. Hayward, cultured rabbit aortic smooth muscle cells Gordon R. Campbell and Julie H. Campbell M.G.L. Ribeiro, A.R. Pedrenho and Electrocyte (Na’,K*)ATPase inhibition induced by zinc is reverted A. Hasson-Voloch by dithiothreitol Graciela E. Hurtado de Catalfo and Polyunsaturated fatty acid biosynthesis from [1-!4*C]20:3 n-6 acid in I. Nelva T. de Gomez Dumm rat cultured Sertoli cells. Linoleic acid effect Hirofumi Ogawa, Tomoharu Gomi, Evidence for a dimeric structure of rat liver serine dehydratase Fusao Takusagawa, Toru Masuda, Takuya Goto, Takanobu Kan and Num-Ho Huh Cristina Tomas-Zapico, Melatonin protects against d-aminolevulinic acid-induced oxidative Jorge Martinez-Fraga, damage in male Syrian hamster Harderian glands Maria Josefa Rodriguez-Colunga, Delio Tolivia, Rudiger Hardeland and Ana Coto-Montes C.E. Evans Bisphosphonates modulate the effect of macrophage-like cells on osteoblast Hong-Wei Zhou, Yong-Doo Park and Lead ion effect on creatine kinase: equilibrium and kinetic studies Hai-Meng Zhou of inactivation and conformational changes Number 6 Molecules in focus Hans-Jiirgen Magert, LEKTI: a multidomain serine proteinase inhibitor with pathophysio- Peter Kreutzmann, Ludger Standker, logical relevance Michael Walden, Katrin Drogemiller and Wolf-Georg Forssmann Johan Van Lint, An Rykx, Getting to know protein kinase D Tibor Vantus and Jackie R. Vandenheede Irmgard Irminger-Finger and BRCA|-dependent and independent functions of BARD] Wai-Choi Leung Short communication David J. Armstrong, Paul Hiscott, Corneal stromal cells (keratocytes) express thrombospondins 2 and 3 Mark Batterbury and Stephen Kaye in wound repair phenotype Vi General papers Franca Cocci, Massimo Miniati, Urinary desmosine excretion is inversely correlated with the extent Simonetta Monti, Eleonora Cavarra, of emphysema in patients with chronic obstructive pulmonary Federica Gambelli, Luigi Battolla, disease Monica Lucattelli and Giuseppe Lungarella Ana M. Gutiérrez, Guillermo Fatty acid profiles and lipid peroxidation of microsomes and mito- R. Reboredo and Angel Catala chondria from liver, heart and brain of Cairina moschata Noxolo Mkwetshana, Ryno The purification and characterization of ,t-calpain and calpastatin J. Naudé and Koji Muramoto from ostrich brain T.B. Ng and Y.W. Lam Solenin, a novel protein with translation-inhibiting activity from the traditional Chinese medicinal fish, the sea dragon Solenognathus hardwickii Diego Alvarez de la Rosa, Chromatin structure analysis of the rat Na, K-ATPase B2 gene 5’- Julio Avila and Pablo Martin-Vasallo flanking region M. Victoria Encinas, Urea-induced unfolding studies of free- and ligand-bound tetrameric Fernando D. Gonzalez-Nilo, ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate car- Jose M. Andreu, Carlos Alfonso and boxykinase. Influence of quaternary structure on protein conforma- Emilio Cardemil tional stability Elizabeth F. da Silva, Converting troponin C into calmodulin: effects of mutations in the Vanessa H. Oliveira, central helix and of changes in temperature Martha M. Sorenson, Hector Barrabin and Helena M. Scofano Andreimar M. Soares, Mn** ions reduce the enzymatic and pharmacological activities of Yoko Oshima-Franco, Carlos A. Vieira, bothropstoxin-I, a myotoxic Lys49 phospholipase A, homologue Gildo B. Leite, Jeffrey E. Fletcher, from Bothrops jararacussu snake venom M.-S. Jiang, Adelia C.O. Cintra, José R. Giglio and Léa Rodrigues-Simioni Hui Zhou, Congyi Zheng, Guolin Zou, G,-phase specific apoptosis in liver carcinoma cell line induced by Deding Tao and Jianping Gong copper-1,10-phenanthroline Marina A. Guvakova, David Boettiger Induction of fascin spikes in breast cancer cells by activation of the and Josephine C. Adams insulin-like growth factor-I receptor Wulin Aerbajinai, Tadayuki Ishihara, Increased expression level of the splicing variant of S/P/ in motor Kiichi Arahata and neuron diseases Toshifumi Tsukahara Book reviews Number 7 DIRECTED ISSUE: CELL MOTILITY Molecules in focus Zahara M. Jaffer and 713 p21-Activated kinases: three more join the Pak Jonathan Chernoff Clare M. Isacke and Helen Yarwood The hyaluronan receptor, CD44 B.J. Perrin and A. Huttenlocher Calpain William Wood and Paul Martin Structures in focus—filopodia Reviews Margareta Nikolic The role of Rho GTPases and associated kinases in regulating neur- ite outgrowth Irina Kaverina, Olga Krylyshkina and Regulation of substrate adhesion dynamics during cell motility J. Victor Small General papers Jareer Kassis, Robert Radinsky and Motility is rate-limiting for invasion of bladder carcinoma cell lines Alan Wells Jeffrey Chou, Donna B. Stolz, Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in Nancy A. Burke, Simon lamellipodia during EGF-induced motility C. Watkins and Alan Wells Silvia M. Goicoechea, Yizeng Tu, Nck-2 interacts with focal adhesion kinase and modulates cell moti- Yun Hua, Ka Chen, Tang-Long Shen, lity Jun-Lin Guan and Chuanyue Wu Gareth E. Jones, Daniel Zicha, Restoration of podosomes and chemotaxis in Wiskott—Aldrich syn- Graham A. Dunn, Mike Blundell and drome macrophages following induced expression of WASp Adrian Thrasher P. Clark, G.A. Dunn, A. Knibbs and Alignment of myoblasts on ultrafine gratings inhibits fusion in vitro M. Peckham Simona Paris, Lorena Za, Analysis of the subcellular distribution of avian p95-APP2, an ARF- Barbara Sporchia and Ivan de Curtis GAP orthologous to mammalian paxillin kinase linker Anna Barbara Hauert, Differentiated HL-60 cells are a valid model system for the analysis Sibylla Martinelli, Camilla Marone of human neutrophil migration and chemotaxis and Verena Niggli Michael C. Brown and Christopher Roles for the tubulin- and PTP—PEST-binding paxillin LIM domains E. Turner in cell adhesion and motility Alice Y. Welch and Ira M. Herman Cloning and characterization of BCAP73, a novel regulator of f- actin assembly J. Sroka, M. von Gunten, Phenotype modulation in non-adherent and adherent sublines of G.A. Dunn and H.U. Keller Walker carcinosarcoma cells: the role of cell-substratum contacts and microtubules in controlling cell shape, locomotion and cytoske- letal structure Number 8 Molecules in focus Tsukasa Seya and Misako Matsumoto A lipoprotein family from Mycoplasma fermentans confers host immune activation through Toll-like receptor 2 IX David S. Latchman 907 Urocortin Marek Tchorzewski 911 The acidic ribosomal P proteins General papers Benedetto Dainelli, Domenico Paludi, 916 A novel glutathione transferase from Haemophilus influenzae which Beatrice Dragani, Roberta Cocco, has high affinity towards antibiotics Daniela Rossi Principe, Massimiliano Petrucci, Felice Mucilli, Angelo Faraone and Antonio Aceto Xiu-Hui Gao, Prem P. Dwivedi, Basal and parathyroid hormone induced expression of the human Sophie Choe, Frances Alba, Howard 25-hydroxyvitamin D _ la-hydroxylase gene promoter in_ kidney A. Morris, John L. Omdahl and Brian AOK-B50 cells: role of Spl, Ets and CCAAT box protein binding K. May sites D. Gakova, R. Cadek, R. Chaloupka, 931 Monitoring the kinetics and performance of yeast membrane ABC V. Vacata, J. Gebel and K. Sigler transporters by diS-C3(3) fluorescence J. Moraczewski, A. Nowotniak, 938 Differential changes in protein kinase C associated with regeneration E. Wrobel, M. Castagna, J. Gautron of rat extensor digitorum longus and soleus muscles and I. Martelly Jiangfeng Su and Kadriye Ciftci 950 Changes in BRCA/ and BRCA2 expression produced by chemother- apeutic agents in human breast cancer cells E. Riley, R. Bolton-Grob, N. Liyou, 958 Isolation and characterisation of a novel rabbit sulfotransferase iso- C. Wong, M. Tresillian and form belonging to the SULTIA subfamily M.E. McManus Wen-bin Ou, Ri-Sheng Wang, Jie Lu 970 Effects of aspartate on rabbit muscle creatine kinase and the salt and Hai-Meng Zhou induced molten globule state Xi-Cheng Wang, Jian Yang, Wei Huang, 983 Effects of removal of the N-terminal amino acid residues on the Lin He, Jiang-Tao Yu, Qing-Song Lin, activity and conformation of firefly luciferase Wei Li and Hai-Meng Zhou Federico Martinez, Aida Uribe, Calcium modulates the ATP and ADP hydrolysis in human placental M. Teresa Espinosa-Garcia, Oscar mitochondria Flores-Herrera, Cecilia Garcia-Pérez and Rebeca Milan Federico Martinez, Aida Uribe, 1004 Differential effects of magnesium on the hydrolysis of ADP and Rebeca Milan, M. Teresa Espinosa- ATP in human term placenta. Effect of substrates and potassium Garcia, Cecilia Gracia-Pérez and Oscar Flores-Herrera Patrick Sauvant, Vincent Sapin, 1017 PAV-1, a new rat hepatic stellate cell line converts retinol into Armand Abergel, Carsten K. Schmidt, retinoic acid, a process altered by ethanol Loic Blanchon, Marie-Cécile Alexandre- Gouabau, Jean Rosenbaum, Gilles Bommelaer, Edmond Rock, Bernard Dastugue, Heinz Nau and Véronique Azais-Braesco Number 9 Molecules in focus Sonya Vengrova, Sandra Codlin and 1031 RTS]—an eukaryotic terminator of replication Jacob Z. Dalgaard General papers Yingfeng Deng, Zhao Wang, 1035 NADPH-dependent GMP reductase isoenzyme of human (GMPR2). Kang Ying, Shaohua Gu, Chaoneng Ji, Expression, purification, and kinetic properties Yan Huang, Xing Gu, Yiran Wang, Yunmin Xu, Yao Li, Yi Xie and Yumin Mao Kate M. Suchanek, Fiona J. May, 1051 Peroxisome proliferator-activated receptor B expression in human Won Jae Lee, Nicola A. Holman and breast epithelial cell lines of tumorigenic and non-tumorigenic Sarah J. Roberts-Thomson origin Christian Schwarzer, 1059 Voltage-dependent anion-selective channel (VDAC) interacts with Shitsu Barnikol-Watanabe, the dynein light chain Tctex! and the heat-shock protein PBP74 Friedrich P. Thinnes and Norbert Hilschmann N. Nunes-Tavares, A. Nery da Matta, 1071 Inhibition of acetylcholinesterase from Electrophorus electricus (L.) C.M. Batista e Silva, G.M.N. Araujo, by tricyclic antidepressants S.R.W. Louro and A. Hasson-Voloch Nandor Miillner, Agnes Lazar and 1080 Enhanced utilization and altered metabolism of arginine in inflam- Andras Hrabak matory macrophages caused by raised nitric oxide synthesis Fernando L. Camolezi, 1091 Construction of an alkaline phosphatase—liposome system: a tool for Katia R.P. Daghastanli, biomineralization study Prislaine P. Magalhaes, Joao M. Pizauro and Pietro Ciancaglini Qiao Wu, Zheng-ming Chen and 1102 Anticancer effect of retinoic acid via AP-1 activity repression is Wen-jin Su mediated by retinoic acid receptor a and # in gastric cancer cells A. Mohamadi-Nejad, 1115 Thermodynamic analysis of human serum albumin interactions with A.A. Moosavi-Movahedi, glucose: insights into the diabetic range of glucose concentration G.H. Hakimelahi and N. Sheibani Youn Bok Lee, Kyung Soo Nam, 1125 Effects of ATP on the stability of enzymes against heat treatment in Il Soo Moon, Sook Shin and 6-aminonicotinamide treated quail In Kook Park Masakazu Ishii, Shunichi Shimizu, 1134 Stimulation of tetrahydrobiopterin synthesis by cyclosporin A in Kazuhiro Shiota, Shinichiro Yamamoto, mouse brain microvascular endothelial cells Yuji Kiuchi and Toshinori Yamamoto Pi-Ling Chang, Mary A. Tucker, 1142 Novel protein kinase C isoforms and mitogen-activated kinase Patricia H. Hicks and Charles W. Prince kinase mediate phorbol ester-induced osteopontin expression Morihiro Ito, Shin-Ichiro Takebayashi, 1152 Up-regulated expression of a novel gene in activated human periph- Katsuzumi Okumura, Takeshi Ohkubo, eral blood mononuclear cells that is a truncated paralog of the Machiko Nishio, Mitsuo Kawano, human system L-amino acid transporter | Hiroshi Komada, Yasuhiko Ito and Masato Tsurudome XI Carminita L. Frost, Ryno J. Naudé and 1164 Ostrich antithrombin III: kinetics and mechanism of inhibition of Koji Muramoto ostrich thrombin Number 10 Molecules in focus Anne T. Reutens and C. Glenn Begley 1173 Endophilin-1: a multifunctional protein Pier Paolo Di Fiore and Giorgio Scita 1178 Eps8 in the midst of GTPases Avery August, Angela Fischer, 1184 The Tec family of tyrosine kinases in T cells, amplifiers of T cell Shengli Hao, Cynthia Mueller receptor signals and Melanie Ragin Review Petr Jezek 1190 Possible physiological roles of mitochondrial uncoupling proteins— UCPn General papers K. San Roman, E. Villar 1207 Mode of action of two inhibitory peptides from heptad repeat and I. Munoz-Barroso domains of the fusion protein of Newcastle disease virus Tomohiko Suzuki, Nobuhiro Sugimura, 1221 Two-domain arginine kinases from the clams Solen strictus and Tomoyuki Taniguchi, Yukiko Unemi, Corbicula japonica: exceptional amino acid replacement of the Takami Murata, Mami Hayashida, functionally important D®* by G Kohei Yokouchi, Kohji Uda and Takahiro Furukohri Guillermo Noriega, Guillermo Mattei, 1230 Rat kidney porphobilinogen deaminase kinetics. Detection of Alcira Batlle and Adela Ana Juknat enzyme-substrate complexes Ying-Xia Zhang, Ying Zhu, 124] Refolding and reactivation of calf intestinal alkaline phosphatase Hong-Wei Xi, Yong-Li Liu with excess magnesium ions and Hai-Meng Zhou Xingjie Liang and Youguo Huang 1248 Physical state changes of membrane lipids in human lung adenocar- cinoma Asq4o9 cells and their resistance to cisplatin Gunilla Westergren-Thorsson, 1256 Correlation between airway responsiveness and proteoglycan pro- Jamila Chakir, duction by bronchial fibroblasts from normal and asthmatic subjects Marie-Josée Lafreniere-Allard, Louis-Philippe Boulet and Guy M. Tremblay Yamileth Angulo, 1268 Structural characterization and phylogenetic relationships of myo- Timoteo Olamendi-Portugal, toxin II from Atropoides (Bothrops) nummifer snake venom, a Alberto Alape-Giron, Lys49 phospholipase A> homologue Lourival D. Possani and Bruno Lomonte Vanderlei Folmer, Julio C.M. Soares 1279 Oxidative stress in mice is dependent on the free glucose content of and J.B.T. Rocha the diet Tonino Bucciarelli, Paolo Sacchetta, 1286 Amino acid sequence of the major form of toad liver glutathione Fernanda Amicarelli, transferase Raffaele Petruzzelli, Sonia Melino, Domenico Rotilio, Nicola Celli and Carmine Di Ilio XII