STEM CELL COIN Regenerative Medicine to the World STEM CELL COIN White Paper Ver,1.0 ©STEM CELL PROJECT ©STEM CELL PROJECT Table of Contents P.3 P.4 P.5 P.6 P.7 P.8 P.10 P.15 P.18 P.21 P.25 P.29 P.32 P.35 P.36 P.37 P.38 P.39 P.40 �2 Important Reminder Important Items Requiring Confirmation What is ICO? Details of Stem Cell Coin Road Map Concepts of Our Project Brief Overview of Our Project Market Sizes and Growth Potential of Regenerative Medicine What is Stem Cell? Indicated Clinical Cases Pathological/diagnostic imaging systems by AI and Blockchain Concept of Virtual Clinic Platform Brief Overview of JASARM Business Expansion Map Brief Overview of Token Sale Token Distribution Bonuses for Major Token Holders Project Team Disclaimer ©STEM CELL PROJECT �3 This white paper describes the first sale of the Stem Cell Coin (SCC). As described in this paper, SCC is a cryptocurrency which has been designed to use for all the services provided by the Stem Cell Project team and its affiliate companies. The SCC token has been created on the basis of Ethereum network, so this token has no nature of securities in any legal jurisdiction. This paper is not for inviting investors or for offering securities by any means in any legal jurisdiction. Please note that purchasing SCC is all definitive and non-refundable. Individual, company and any other organization must consider risks of purchasing SCC and its costs and benefits carefully. Information contained in this paper and the whole document is not comprehensive. Also, this paper does not represent privity of contract between our company and token purchasers. The accuracy, reliability and integrity of materials included in this paper or provided other sites in association with this ICO are not guaranteed, and we accept no legal responsibilities for that. For other companies and individuals, SCC does not represent, warrant or promise truth, accuracy and integrity of any kind of information described in this paper, and SCC does not intend to do so. SCC also disclaims representation, warranty or promise on them. Disclaimer
 ©STEM CELL PROJECT �4 Purchasing SCC can carry a serious risk. We consider that the purchasers have already accepted the following risks before buying the coins. • The purchasers recognize that some services in the Stem Cell Project are currently under development and a major modification may occur in the period to the start of the services. • The purchasers understand that expectations for the forms and features of the Stem Cell Project may not be fulfilled due to various reasons. • The purchasers understand that some cryptocurrency exchanges may deny connection to this project although SCC devotes best efforts to connect to major exchanges and, as a result, the liquidity provided through platform may become lower than that expected in this paper. • The purchasers understand that the date of official release may be late although SCC devotes best efforts to start as scheduled. • There may be broad fluctuations of the value of SCC and its lowering due to various reasons. • SCC will be issued in NEO blockchain. Therefore, transfer of SCC or purchasers’ capability of holding the coin safely may be affected by troubles of NEO protocol or unexpected function. • Important Items Requiring Confirmation 
 ©STEM CELL PROJECT �5 ICO (Initial Coin Offering) is a method for financial arrangements by issuing an original digital token and selling it. This is not to assign equity like stock funding but to simply sell the token like reward- based crowdfunding. The token is not recognized as a “cryptocurrency” at the time of selling, which means that the ICO is not the method for “financial arrangements” by strict definition but is for selling the token. Thus those who buy it are not “investors” for the project but are the “purchasers of the token.” At the point in time, the SCC token cannot be used as repayment for a consideration for unspecified persons, and it is considered that this ICO project fits the above-mentioned definitions since it is in a situation where there is no exchange market between the token and the legal currencies, Bitcoin, and any other existing cryptocurrencies. What is ICO?
 Purposes of ICO All the produced funds will be used for development of the Stem Cell Project. 1. Development/introduction of payment system for the cost of Stem Cell treatment at our own hospitals/affiliate clinics 2. Development/introduction of pathological/diagnostic imaging systems by Artificial Intelligence (AI) and Blockchain 3. Development of Virtual Clinic Platform 4. Costs of construction and expansion of hospitals for Stem Cell treatment 5. Research and clinical work for pharmaceuticalization of stem cells 6. ©STEM CELL PROJECT �6 Brief Overview of Stem Cell Coin
 Name of Token Currency Code Total Number Max. Number of Token for Sales Selling Price of Token
 Type STEM CELL COIN
 SCC
 5,000,000,000 SCC 1,200,000,000 SCC
 1SCC = 0.06～0.14USD ( × ETH or BTC or NEO ) 
 Nep5 Neo Platform May fluctuate depending on sales period TOKEN NAME SCC Maximum token supply 5,000,000,000 SCC Standard NEO NEP-5 Token Minimum purchase 20,000 SCC Maximum purchase 200,000,000 SCC Public Sale offering price per token $0.14 Accepted forms of payment BTC / ETH / NEO privatesale begins October 16, 2018 18:00 GMT+4:00 Pre-ICO Sale begins May 16, 2018 18:00 GMT+4:00 Pre-ICO Sale ends October 15, 2018 18:00 GMT+4:00 privatesale ends October 30, 2018 18:00 GMT+4:00 Token use Utility Token Unsold tokens Burned ©STEM CELL PROJECT �7 Road Map ・After ICO period, no. of token for sales will be burnt to make it 50% of total no. of token. ・If all the no. of token for sales are sold before the last day of each period, the selling schedule will be accelerated. ・The schedule/content can be changed depending on progress of the project. Planning to develop Singapore Regenerative Medical Center Planning to develop China Regenerative Medical Center Osaka Regenerative Medical Center/Scheduled to open Tokyo Regenerative Medical Center/Scheduled to open Fukuoka Regenerative Medical Center/Open Kyoto Regenerative Medical Center/Scheduled to open ©STEM CELL PROJECT �8 In industrialized countries including Japan, which have increasingly aging populations, the number of people suffering chronic diseases are increasing. Because of development of public transports, people don’t exercise enough and begin to have obese and metabolic syndrome. Thus health maintenance/promotion captures their interest. Concept of “health care” becomes very important nowadays. On the other hand, the number of qualified professionals such as medical doctors and nurses is decreasing. Time to wait for the physical examination by a doctor is getting longer, and the burden of the medical experts is also getting heavier year after year. In such a circumstance, we will develop “AI Personal Doctor” on the basis of the concept “eSelfcare” for health maintenance of people around the world. We will provide “Aging Well Concept” which is self-maintenance of own health by oneself to the whole world. Concepts of Our Project From 60% to 80% of world population have a lack of exercise 8.6 million people in the world suffer some chronic diseases Assumed 1 billion people in the world become 60 years old or over by 2025 Number of qualified professionals are reducing People tend to have a lack of exercise as their cultures are developing. As a result, they experience body weight gain which leads to chronic diseases such as diabetes mellitus and hypertension. There have been tools which can lead them to a healthy state and maintain the state. Our challenge is to find out how to utilize these tools to obtain better results for becoming healthy. By 2025, it is assumed that the population of 60 years old or over is increased further. In addition to the currently aging industrialized countries, the developing countries with rapid population growth will soon become aging societies. Do you think their dreams of life with peace, safe and comfortable will come true? What should we do before worldwide aging societies become reality. 8.6 million people in the whole world, and the number is growing at a phenomenal speed. In fact, it is estimated that about ¾ of causes of death in the world will be chronic disease by 2020. If chronic diseases are well managed by patients, their family members and health care teams, patients can enjoy their life healthier and also the burden of treatment costs can be minimized. Additional burden will cause a crisis. According to the report in 2006 by WHO, we need 4.3 million more medical doctors, nurses and medical support staff, and such a situation is not expected to improve in the future. They are already insufficient in number, and how can we keep providing essential medical and welfare services? ©STEM CELL PROJECT �9 To obtain vital data such as body temperature, blood pressure, and pulse rate easily, we need technologies to sense the physical quantities. The obtained biological information are not discarded after temporal usage but accumulated and the course will be followed. In order to make the above happen, high-security network which can transfer data freely is necessary. When the 2 technologies are integrated, people’s lifestyles and environments will change significantly. The change is what we are providing: Future medical services achieved by IoT and Blockchain AI Personal Doctor (Keep all the doctors in the world for oneself) Our vision is to bring a new structure with AI and Blockchain to the old medical system. This can be a breakthrough in the healthcare industry and bring affluent society in which people live in health. 2 technologies playing a role in the future health will open new doors The revolution, however, doesn’t destroy the structure of the current medical services, but rather aims to complement the current services and expand their breadth. As an example, utilization of cutting-edge sensing technologies and chatbots reduce the burden of medical staff and improve the accuracy of medical examinations, and also application of AI analysis and Blockchain create a new medical service in the area of private practice (no health insurance applicable). We aim to spread these across the world Our final goal is to create a environment that everyone can always receive high-quality medical services wherever they are. Labor force in the medical field also decreases as the population decreases. In such a situation, the condition to receive advanced treatment becomes even tougher for patients. Along with improving the skills of doctors, procedures associated with medical examinations need to be reduced. We revolutionize medical services with AI and Blockchain. ©STEM CELL PROJECT �10 Stem Cell Project is a medical project mainly focused on the following 2 points: Development and popularization of (1) a means of payment for the costs of stem cell treatment at the affiliate hospitals and (2) pathological/diagnostic imaging systems by using AI and Blockchain. The followings are the 4 main purposes of our project: 1. Make stem cell treatment possible to pay in cryptocurrency Stem cell therapy helps to activate weakened cells and proliferate important cells declining in number daily. After stem cell administration, the cells are circulating through the body. Once finding out damaged tissues, the stem cells are activated by themselves and trying to repair and regenerate the tissues. This therapy shows promise for treatment of anti-aging, diabetes mellitus, etc. However, currently, stem cell therapy can be provided only in medically advanced countries. In recent years, stem cell therapy has captured the world’s attention. So, we are expecting worldwide financial inflow to regenerative medicine by means of cryptocurrency payment. 2. Introduction of pathological/diagnostic imaging systems with AI and Blockchain We are developing the near-future health check system which can share automatic diagnoses with images and pathological data among clinics and hospitals in the world by using AI and Blockchain technologies. We will let the system grow to the level that can screen medical big data rapidly and accurately. We are also planning to use the provided big data for revealing relationship to cancers on the basis of the patient information such as nationality, race, gender and age. Brief Overview of Our Project ©STEM CELL PROJECT �11 3. Development of Virtual Clinic Platform When patients experience illness/disorders, they often have following questions, “Which hospital should I go?” and “Which department should I choose?” Also visiting hospital just for receiving medicines is wasting time and becomes burden for patients. In order to solve such problems, we develop Virtual Clinic Platform which can make patients feel a closer connection to doctors by using the network among the member hospitals/clinics of Japan Society of Aesthetic Regenerative Medicine and AIbot diagnosis, remote medical checkup system, search/reservation of hospitals/clinics. All the payments in the platform can be done in SCC. ※AIbot diagnosis: AI can predict suspected patient’s disease(s) only with asking questions regarding symptoms and affected parts. ※Remote medical checkup system: Doctors can examine patients who cannot visit medical institutions for reasons of their living environments by using video calls etc. 4. Research and clinical work of therapeutic formulations with stem cells The final goal of our Stem Cell Project is “pharmaceuticalization of stem cells.” By doing research and clinical work of therapeutic formulations with stem cells and putting them into public circulation, we will be able to achieve our aims to give more opportunities to those who need regenerative medicine and to optimize the treatment costs. Keeping development of the world’s first “Cell Bank” in mind, we also create a surrounding in which people with diseases can be treated with their own cells which took and stored beforehand at their healthy state. ©STEM CELL PROJECT �12 More Details on 1. Stem cell therapy has been attracting worldwide attention in recent years, however, the therapy can be currently provided only in 5 countries such as the US, Germany, Switzerland, Russia (only at governmental institutions), and Japan. Amid increasing demand for stem cell therapy especially in Asia, the therapy can be currently provided only in Japan among other Asian nations. In Japan, hospitals/clinics which can provide stem cell therapy need to obtain approval of Class II Regenerative Medicine accredited by the Ministry of Health, Labor and Welfare. One of our project team, Association of Medical Corporation Koge-Kai, is planning to obtain the approval of Class II Regenerative Medicine and is having a clinic where stem cell therapy can be given. Although we have the clinic in which a number of people can be treated, the payment method for the treatment costs is an issue. Especially in China, there is the regulation on annual limit of taking Chinese yuan out of China, and thus, although the demand is increasing, it is currently difficult for them to bring their own currency to other countries for the treatment which costs about 6 to 8 million yen per time. Introduction of a payment system in cryptocurrency can solve this issue. While the number of individual investors holding cryptocurrencies such as Bitcoin is growing, we are planning to expand customers of our hospitals/affiliate clinics by using SCC as a payment method. ©STEM CELL PROJECT �13 More Details on 2. The final goal of this system is to bridge the gaps among the worldwide medical technologies. This system has been developed because of lack of medical specialists which is the issue of the current healthcare industry. Rare diseases and diseases which are difficult to detect tend to be found out by thorough examinations in university hospitals or general hospitals, and there are many cases which could not be detected or treated at minor hospitals/clinics. This can be associated with the major issue of lack of pathologists. A similar situation can be seen in other medically advanced countries. Especially in China, there are only around 10,000 pathologists for the population of 1.4 billion, which is a serious scarcity of labor. As a result, patients gather at major hospitals. Brief overview of the system is that data of CT and X-ray images are scanned by AI system in which medical big data have been introduced. This can lead to early detection of variety of diseases and detection of rare diseases. Furthermore, by using this system on Blockchain, diagnostic data can be shared at the medical institutions with the system, which can lead to medical technology improvement. Thus, even the minor hospitals and developing countries can manage high-level medical technology, and gaps of the medical technology will be filled by this system. More Details on 3. We propose Virtual Clinic Platform. Patients can receive various medical services on 1 device online wherever they are. A variety of contents will be added such as remote medical checkup system, chatbot and translation function. ©STEM CELL PROJECT �14 More Details on 4. This is directly connected to the point of our philosophy “Regenerative Medicine to the World.” Stem cell therapy has been attracting worldwide attention to a variety of symptoms and anti-aging effect; however, only some wealthy people can receive the therapy (mostly for anti-aging) due to the high cost. Thus stem cell therapy is not considered as a therapy for patients in need. For the issue, our project is aiming to “optimize stem cell therapy cost.” Since our project team has been established a special technology to culture stem cells rapidly and accuracy, mass culturing is possible. By improving this technology and optimizing the treatment cost, we can give more opportunities to those who need regenerative medicine. We aim to make regenerative medicine closer to our life by pharmaceuticalization of stem cells on the basis of research and clinical work. Currently, the clinics of our project team provides stem cell treatment under the approval of Class II Regenerative Medicine accredited by Ministry of Health, Labor and Welfare, however; approval of Class I Regenerative Medicine is essential for pharmaceuticalization of stem cells. We will obtain appropriate approval while the project is going further and then provide regenerative medicine to the people who need it. Advantages of our project are not only providing IT services in healthcare, but also holding a medical corporation, JSARM and clinics in the team. Our aim is not to raise funds for startup like a general feature of ICO, but to grow our business further. We can introduce and operate the payment system and diagnostic imaging system at our own clinics first, which is because the Stem Cell Project includes the medical corporation. ©STEM CELL PROJECT �15 The market sizes of regenerative medicine will be 2.5 trillion yen on Japanese market and 38 trillion yen on the world market in 2050, and it is expected to be enormous economic effects in the near future. Market Sizes and Growth Potential of Regenerative Medicine
 <Method of calculating market size in Japan> “market size of regenerative medicine” = “no. of patients *1” x “costs per patient *2” *1: “no. of patients” = “no. of latent patients in Japan” x “application rate of regenerative medicine” *2: “costs per patient” = “unit price of products/processed products” + “medical charges for regenerative medicine (eg. Technical fee)” <Method of calculating market size in the world> “market size of each country” = “current market of regenerative medicine in the country *1” x “adoption rate of regenerative medicine *2” *1: “no. of patients” x “costs per patient” (same as the method for the Japanese market” *2: Estimated from population, income (commodity prices), developing items, existing market, R&D budget, etc. 2012 9 billion yen 2012 9 billion yen 2020 95 billion yen 2030 1 trillion yen 2050 2.5 trillion yen 2020 95 billion yen 2030 1 trillion yen 2050 2.5 trillion yen