www.rxprep.com RxPrep THE REVIEW PROGRAMS TRUSTED BYTOPSTUDENTS, SCHOOLS AND EMPLOYERS The RxPrep® Difference NAPLEX,® MPJE® & CPJE Reviews Not surehowtolearnitall?The RxPrepVideosandtheTest Bank Assessmentsmatch toeachchapterinthisCourse Book.The questions intheTest Banks cover the must-know basic competencydruginformation.Find out what you know and what you need to know before you take the exam.Watchvideos and take assessments on your phone or . tablet;downloadtheRxPrepapptoaccessonthego READ: Includes the simplest and most complete CD calculationsandbiostatisticsreviews.It'sallhere,ineasy ATTEND:Liveorstreamingvideoreviewsessions. :Q=iJ steps,forcompleteexamknow-how. The RxPrep Course Book is the student-preferred resource for NAPLEX. Includes all topics tested with PRACTICE:Noneedtoguess-exam-styletestsletyou must-knowkeydrugsandstudytips. knowwhenyouarereadytotest-anddowell. The RxPrepTest Banks contain case-rich,exam-style WATCH:Pair theCourseBook withvideolecturesthat questionsthatcoveralltherequiredmaterial.Includes 0' •M emphasizetherequireddruginformation. cumulativepracticeexam. Focusontopicsthatneedafreshreview,oruseavideo tobringupatopicscore. UPDATED:Annually.Current,completeandreadyfor exampreparation. ORDERTHEVIDEOANDTESTBANKSONLINEATWWW.RXPREP.COM CONTACTRXPREPFORLIVEREVIEWSANDGROUPRATES [email protected] l ... J«U.* < MvPashboafd II r Prep i WelcomeloRxPrep . 3 : CPJEReviews /jg i ) 3 RxPrep’s Ml 9 S MPJEAND 3 • & CPJEREVIEWS AtiootUa CogOut CourseManual, PracticeTests,Videos andLivereview DownloadtheRxPrepapptostudyonthego ^G011oIoIOgKlePlay ©2019 ©2020RXPREP,Inc. Allrightsreserved.Materialcontainedinthisbookcannotbedistributedorreproducedwithoutpermission. Theauthorsingoodfaithhavemadeeveryattempttoensurethattheinformationincludedinthisbookisaccurateandupto date.However,thecontentisintendedforinstructionalpurposesonly,thereforetheauthorsmakenoguarantees,offerno warrantiesorrepresentations,noracceptanyliabilitieswithrespecttotheaccuracyofthecontentcontainedwithin. TheRxPrepTestBankassessmentsandVideoLecturesforNAPLEX,andtheMPJEandCPJElawreviewcoursescanbefound ontheRxPrepwebsiteatwww.rxprep.com.Clickon"Store.” 2020 NAPLEX COURSE BOOK ® Study Guide for the NAPLEX and Clinical Content for the CPJE for those testing in 2020 , KAREN SHAPIRO PHARMD BCPS / AWV CHELSEA BOMBATCH PHARMD BCPS / / AMY DREW PHARMD BCPS ^VNA / / . MM STEPHANIE D GARRETT PHARMD BCPS / / ANGIE VEVERKA PHARMD BCPS / / 2020Contributors CAITUNDAVIS REZATAHERI PHARMD BCPS PHARMD,MBA / . KARENGOUD MICHAELJ FREUDIGER PHARMD BCPS PHARMD APH,BCPS, / BCGP / IMP/to MINDYHOLCOMBE PHARMD BCPS,BCPPS D.RAYMONDWEBER / PHARMD BSPHARM, o / DACYLIM BCOP,BCPS,RPH CO o EDITORIALASSISTANT LU c AND ;o TESSAOVERMAN MS.SHANNONZINDA CO PHARMD,BCPS *7 BOOKDES/GNAND PRODUCTION ° ?0z CHAPTERTABLEOFCONTENTS INCIUCMNGREQUIREDFORMULAS 3 GramsofNitrogenFromGramsofProtein 152 PREPARINGFOR NAPLEX 1 IMMUNIZATIONS ti CorrectedCalciumforAlbumin<3.5 159 ^7 12.CalculationsIV:Clinical. 166 &TRAVELERS 314 I U BodyMassIndex(BMI) 166 IdealBodyWeight(IBW) 167 AdjustedBodyWeight(AdjBW.-J 167 SelectingandCalculatingPatientWeights 168 1.PreparingforNAPLEXwiththe RowRates.... - 169 RxPrepCourse 3 DropFactor. - 172 20.Immunizations 316 QuickGuides 13 Dehydration 174 21. Travelers. 333 HowtoUsetheRxPrepCourseBook...„.14 Cockcrott-GaultEquation.. 175 TopOutpatientDrugs .15 ArterialBloodGases(ABG) 177 INFECTIOUSDISEASES 340 TopInpatientDrugs.... 19 AnionGap 178 TopOTCDrugs 23 pHCalculations 179 RequiredFormulas. 25 PercentIonization. .182 !»•••«•«»* ... DiagnosticTests 27 DrugConversions. .183 MedicalTerms...M*»M***4**»«*»*«»»M«*M**M«»M*lt(M430 AbsoluteNeutrophilCount(ANC) 184 nm«fM CommonMedicalAbbreviations 39 13.CalculationsV:Exam-Style 22.IDI:Background&Antibacterials MathPractice 185 byDrugClass 342 PHARMACYFOUNDATIONS 23.IDII:BacterialInfections 375 PART1 44 BIOSTATISTICS 198 M T 24.IDIII:Antifungals&Antivirals 398 25.IDIV:OpportunisticInfections 412 26.HumanImmunodeficiencyVirus 415 ••••••••< L < 4 ^ CARDIOVASCULAR 2.LearningBasicScienceConcepts 46 14.Biostatistics 200 CONDITIONS 440 3.LearningDrugInteractions 55 3 Mean,MediumandMode 202 . 4.LearningLabValues&DrugMonitoring 71 Risk RelativeRisk(RR). ....207 .. 5.LearningDrugReferences.... 81 RelativeRiskReduction(RRR) ..208 AbsoluteRiskReduction(ARR)., 208 6.LearningDrugFormulations 91 . NumberNeededtoTreat(NNT) 209 7.LearningIVMedications 99 NumberNeededtoHarm(NNH) 210 27.Dyslipidemia... 442 8.AnsweringCase-BasedExamQuestion 106 OddsRatio(OR) .210 SS FriedewaldEquation 443 SS TemperatureConversion—s HazardRatio(HR) 211 28.Hypertension 458 (Fahrenheit Celsius) 108 SensitivityandSpecificity .214 29.IschemicHeartDisease 474 .. »•••••••• CALCULATIONS 114 COMPOUNDING& 30.AcuteCoronarySyndromes. ..481 HAZARDOUSDRUGS 223 31.ChronicHeartFailure 489 •••••••••••a 32.Arrhythmias 505 33.Stroke 517 ANTICOAGULATION& 9.CalculationsI:MathBasics... 116 BLOODDISORDERS 524 •••••••••••••a SS Liquid(Volume)Conversions.... .117 15.CompoundingI:Basics ••••••••••••••••••••••••••225 Solid(Weight)Conversions 117 16.CompoundingII:Equipment, HeightConversions 117 Stability&Excipients 249 10.CalculationsII:Compounding 128 8 MmWeighableQty(MWQ) 252 ••••••••••••••••••••• SS PercentageStrength 128 17.CompoundingIII:Documentation RatioStrength 132 &Preparation.. 267 34.Anticoagulation.... 526 PartsPerMillion(PPM) 134 35.Anemia 542 SpecificGravity(SG). 155 RENAL&LIVER DISEASE 288 , 36.SickleCellDisease 550 Dilution&Concentration(ChangingStrength orVolume) — 136 •44444444444444444*444444 EYES,EARS,NOSE& SKIN Alligation 137 CONDITIONS 554 Osmolarity 139 Mi m Isotonicity(EValue) I42 MolesandMillimoles 144 Milliequivalents.. . 146 18.RenalDisease 290 U»UUMtitUu*U> KCISolution(Oral)toTablets- — see#61 19.Hepatitis&LiverDisease 302 11. CalculationsIII:Parenteraland SS EnteralNutrition 148 37.AllergicRhinitis,Cough&Cold .556 DeterminingFluidNeeds 149 38.CommonConditionsoftheEyesandEars.566 TotalEnergyExpenditure 150 39.CommonSkinConditions. 573 ParenteralNutrition ..151 EnteralNutrition.••4444•44•44444««4444444(44*44«44»#4444»4444*>*4«>»4«4«««»*4»«4444444 151 8 TimetoBurn(TTB)4«444444•••44«•»4444••»•44 587 CHAPTERTABLEOFCONTENTS INCLUDINGREQUIREDFORMULAS PULMONARYCONDITIONS& PAIN/RELATED GASTROINTESTINAL TOBACCOCESSATION 590 CONDITIONS CONDITIONS 954 40.PulmonaryArterialHypertension .592 58.Pain 796 72.GastroesophagealRefluxDisease 41. Asthma 599 59.Migraine 818 &PepticUlcerDisease 956 42.ChronicObstructivePulmonaryDisease...617 60.Gout 825 73.Constipation&Diarrhea 966 43.TobaccoCessation 629 74.InflammatoryBowelDisease 975 ONCOLOGY 831 75.MotionSickness 983 ENDOCRINECONDITIONS..634 PHARMACYFOUNDATIONS PART2 986 61.Oncologyl:Overview&SideEffect 44.Diabetes 636 Management 832 62.OncologyII:CommonCancerTypes t% InsulinConversions: beginsat656 InitiatingBasal-BolusInsulininTypeIDiabetes &Treatment 851 76.MedicationSafety&QualityImprovement...988 Insulin-to-CarbohydrateRatio: •2 BSACalculations,usingMosteller 861 77. DrugAllergies&Adverse Ruleof500forRapid-ActingInsulin DrugReactions.... 1000 Insulin-to-CarbohydrateRatio: PSYCHIATRICCONDITIONS..878 78.Pharmacokinetics 1009 Ruleof450forRegularInsulin CorrectionFactor:1,800Rulefor 21 Bioavailability(F) 1011 Rapid-ActingInsulin VolumeofDistribution(Vd) 1012 CorrectionFactor:1,500RuleforRegularInsulin Clearance i......ir.•» • 1013 CorrectionDose 3 EliminationRateConstant(Ke) 1016 45.ThyroidDisorders 664 PredictingDrugConcentrations 1016 ••••444«4«4*4»»**444*4«••••••••••• 63.Depression 880 Half-Life(Tl/2) . 1017 46.SystemicSteroids& u*Uuutuuu«uu»uuu>iiuuiiiuii 64.Schizophrenia/Psychosis 892 LoadingDose(LD) 1019 AutoimmuneConditions 671 ... 65.BipolarDisorder _ 901 79.Pharmacogenomics 1020 MALE& FEMALEHEALTH....692 66.AttentionDeficitHyperactivityDisorder 80.DietarySupplements,Natural& (ADHD) 905 ComplementaryMedicine 1024 67. AnxietyDisorders 913 81. EmergencyPreparedness,Toxicology &Antidotes 1033 68.SleepDisorders:Insomnia,RestlessLegs Syndrome(RLS)&Narcolepsy 918 PATIENTCASES 1041 47. Contraception&Infertility 694 NEUROLOGICCONDITIONS.924 48.DrugUseinPregnancy&Lactation 707 •••••••44444 49.Osteoporosis,Menopause& TestosteroneUse 713 50.SexualDysfunction 729 82.Cases,Exam-StylePractice ,.1042 51. BenignProstaticHyperplasia(BPH) .734 .. 69.ParkinsonDisease 926 52.OveractiveBladder 740 70.Alzheimer’sDisease 932 INDEX. ...1050 SPECIALPOPULATIONS 746 71. Seizures/Epilepsy .937 22 PhenytoinCorrectionforAlbumin<3,5 946 ByClassification+DrugName 1050 53.Acute&CriticalCareMedicine 748 ••••»441 54.PediatricConditions 763 55.CysticFibrosis 773 56.Transplant 779 57. WeightLoss 789 CONTENT LEGEND (jjf)=RequiredFormula KEYDRUGGUY ANDSTUDYTIPGALTABLEOFCONTENTS PHARMACYFOUNDATIONS RENAL& LIVER DISEASE 288 CARDIOVASCULAR PART1 44 CONDITIONS 440 18.RenalDisease 290 2. LearningBasicScienceConcepts 46 SelectDrugsthatCauseKjdneyDisease 292 27.Dyslipidemia 442 . ReceptorPharmacology .49 : CrGvs.GFR—, .292 SelectDrugsCondrtionsthatCanRaiseLDL 3.. LPheaarmrnaicnogdyDn_raumgicIsn:PtehararmcaticoonsD..ynamics .5555 . SACelCecInthDirbuitgosrsthaantdRAeRquBisrefoirADlobsuemoinruTriIan..te—rvalmCK—D.229943 . aDnedtetormrTinriignlgycSetraidtiensTreatme.ntIntensity „ „_443 / SelectDrugsthatareContraindicatedinCKD 294 BasedonPatientRisk 445 RanisdkOwpitihoiCdosncurrentUseofBenzodiazepines 56 SelectDrugsthatRaisePotassiumLevels 298 . StatinEquivalentDoses 446 :. CPCYhYaPPrIImnndhauicbocitekoirnrssetics:Pharmaco Kinetics — —655097 1.:9.HCStoeemppspaafotnirtsTiosrne&aotfiLnHgievSpeearvtieDtirseisVHeiyraupsseeerksalemia -323090293 2i.8.HDMeaytneparemgriintneginnMgsyAaiodlgdnia-OsnTreatmentBasedonPatientRisk>..4.44544886 . 4. LearningLabValues&DrugMonitoring 71 .. DAAMechanismsandRegimens 303 BloodPressureMonitoring 460 — TherapeuticDrugLevels -80 Interferons 307 DrugsthatCanIncreaseBloodPressure 460 5. LearningDrugReferences.... > 81 . LabTestsforLiverDisease „ — -309 . HypertensionGuidelineRecommendations 461 i “Color"DrugReferences„ .89 SelectDrugswithBoxedWarningforLiverDamage 310 KeyIVHypertensionMedications.—. .472 6. LearningDrugFormulations 91 29.IschemicHeartDisease 474 7i. PLaetachrnFrineqguIeVncMy.e....d.ications— 9997 I&MTMRUANVEIZLAETRISONS 314 3.0.TArceautmteeCntoArpopnroaarcyhfSorySntdabrloemIscehsemicHeartDisease 448715 DrugswithLeaching'Adsorption/AbsorptionIssues 20.Immunizations 316 j DrugTreatmentofACS 482 withPVCContainers 101 . VaccineTiming&Spacing 319 DrugsforSecondaryPreventionAfterACS .... 488 ^-* CCDProooommNtemmocttooRFnnreoDDfrmrriguuLeggirssgahwwtetiiDtthhuDFriiinlltuegerAnRdtemSqouinliurisetitmoranetinRotensquirements 111100004331 * IIPnnnvfleuauelimdnzCoacooVncatrccaacilninVdeaicTcaciptiinso.en.Isntdo—icVaaticocnins.ati.on.. 332205 3.1.CSSieghlnerscotanDnirdcugSHsyemthaparttotCmFasausoilefuSoreyrsWtoolircsHeneaHretaFratiFluareilure 448499901 SequenceandIntervals .. 328 8. AnsweringCase-BasedExamQuestion 106 21.Travelers 333 TreatmentofChronicSystolicHeartFailure. 492 . SelectDrugsandConditionsthatAlterVitalSigns 109 . 32.Arrhythmias 505 . IdentifyingMedicationTherapyProblems no DrugsforTravelers'Diarrhea .335 TheHeart'sNaturalPacemakerandArrhythmias 505 TravelVaccines 336 SelectDrugsthatCanIncreaseorProlong CALCULATIONS 114 theQTInterval— — .... ... 508 INFECTIOUSDISEASES•••••••••340 . ClassifyingDrugswithVaughanWilliams 508 9. CalculationsI:MathBasics 116 22.IDI:Background&Antibacterials ; AfibRatevs.RhythmControl 509 .. CommonConversions 117 byDrugClass 342 33.Stroke 517 *..* HRDSoareuttwitgointCRogoeURnlapovteuiPornrsndoisopohnoinsprtst—ihoensExam „, ..111122115587 ... CKKeeoyymFFmeeaaottnuurrReeesssooisfftPCaeennptiPhcaialltliohnsospgoerninss ... 333455602 A. NSigTnsIaCndOSyAmpGtomUsoLfSAtroTkeION& 518 1s0.FRCoealaloldcwyuttlohaeStiRuobunmlessitIoYI:foCMuraoAtmhn.spwoeur?nding 111222877 ...* KKAeemyyinFFoeegaattlyuucrreeosssioodffeCQs:auGrinboaooplodennNeeesmwss,BadNews.. 333555835 3B4L.AOntiOcoDaguDlaItSioOn RDERS 525246 — — . KeyFeaturesofMacrolides 359 x AnticoagulantsareforBloodClots 526 .> DCiosmsomcioantioIVnFPlauritdicsle-svs.V„alence 114269 . KKeeyyFFeeaattuurreessooffSTeutlrfaamcyectlhinoexsazole/T-nmethopnm „336601 .* CCoonavgeurlasitoionnbCeatwsceaedneAnticoagulants 553227 11. CalculationsIII:Parenteraland KeyFeaturesofNitrofurantoin —368 : WarfannTabletColors — 535 . EnteralNutrition 148 . DrugsofChoice/ActiveDrugsforSpecificPathogens.....369 35.Anemia .542 CalonesProvidedfromMacronutrients .151 NoRenalDoseAdjustmentRequired —370 . AssessingandTreatingIronDeficiencyAnemia- 544 12.CalculationsIV:Clinical 166 . 23.IDII:BacterialInfections 375 SelectDrugsthatCanCauseHemolyticAnemia 549 HeightinInches. 168 . TimingofPerioperativeAntibiotics 377 36.SickleCellDisease 550 . FinalVolumeofCompoundedIVSolutions 171 . AOMTreatmentinKids:WhentoConsiderObservation...379 KeyVaccinesinSickleCellDisease 551 InterpretingABGs 177 CAPPatientAssessment(StepwiseApproach) 382 13.CalculationsV:Exam-Style . RIPETherapyforTB 386 MathPractice 185 CdifpaleGuidelineRecommendations 394 EYES,EARS,NOSE& SKIN CONDITIONS 554 MathisReadyforNAPLEXWhen .197 : SymptomsofCommonSTls 395 . Gonorrhea&Chlamydia:TheyOftenGoTogether—....396 37.AllergicRhinitis,Cough&Cold .556 BIOSTATISTICS 198 . PenicillinPregnancyPuzzler 396 DiphenhydramineInPharmacy;It'sEverywhere 559 14.Biostatistics 200 2.4.ILDymIIeI:DAisenatsifeuonrgRainlgsw&orAm?ntivirals.. 339987 .. PCeoduigahtnacnCdoCuoghldaCnodmCbooldPTroredautcmtse:nWt•hCaat'suitnioanNNaemedee?d....556645 ; ICnetenrtprarelTtienngdCeonncfyidCeanlcceulIanttieonrvsals 220052 . KeyIssueswithAzoleAntifungals .400 38.CommonConditionsoftheEyesandEars...566 . RoundingRulesforNNTandNNH 210 25.IDIV:OpportunisticInfections 412 DrugsthatCanIncreaseIQP — 567 26.HumanImmunodeficiencyVirus ...415 . GlaucomaTreatmentGoal:DecreaseIOP. .567 COMPOUNDING& . INSTI-BasedRegimen(INSTl*2NRTIs) 4I8 ^ CChoamnmgeosnoDrrDuagmsaKgneo—wn—toC.auseVision 571 HAZARDOUSDRUGS 223 ^ SingleTabletRegimens 419 39.CommonSkinConditions 573 1.5.CompoundingI:Basics ....225 ti KKeeyyFFeeaattuurreessooffNNNRRTITsIs 442203 . AcneTreatmentSummary 574 Pharmacopeias .226 — HazardousDrugsontheNIOSHList.... .228 .s PKIeaynFdeaPtKurBeosoosftePrisDrugInteractions „442295 ISOAirQualityinthePEC 233 KeyFeaturesofINSTIs 430 16.CompoundingII:Equipment, Administration(Food)Requirements— „.434 Stability&Excipients 249 . ARTAdverseEffectsbyClassandAgent.... 435 : TheHLBNumber 257 DispenseinOriginalContainer••UIUU* 436 17CompoundingIII:Documentation &Preparation 267 . ReducingParticleSize&CakeBaking 271 . Suppositones 277 DeterminingtheBUDForCSPs .284 KEYDRUGGUYANDSTUDYTIPGALTABLEOFCONTENTS 68.SleepDisorders:Insomnia,RestlessLegs PULMONARY CONDITIONS& SPECIALPOPULATIONS 746 Syndrome(RLS)&Narcolepsy 918 TOBACCO CESSATION 590 53.Acute&CriticalCareMedicine 748 ^ SelectDrugsThatCanWorsenInsomnia. 919 . 40.PulmonaryArterialHypertension 592 .. DopamineDosing .•••••••••*•••••••titinnrna753 EzTipforExcellentZzzzzz(Sleep) •>••»•••.«.*i•• 919 ^41.SAelsecthtDmruagsthatCanCausePulmonaryFibrosis. 559998 : TGwenoeCraolmPrminocnipCleasufsoersTorfeIaCtiUngInSfehcotcikons 7.75565 NEUROLOGICCONDITIONS.924 . Spirometry;TestsLungFunction . TreatingADHF„ liuUlul .756 69.ParkinsonDisease 926 (HowWelltheLungsWork) 600 54.PediatricConditions 763 . DopamineBlockingDrugsthatCanWorsenPD 926 ; MDIsandDPIs. .607 . AvoidinPediatrics..— .770 . ParkinsonDisease:TheCause,Symptomsand . WithaSpacerMoreDrugGetsIntoTheLungs 611 55.CysticFibrosis 773 PnmaryDrugTreatment 927 42.ChronicObstructivePulmonaryDisease...617 . InhaledMedicationsforCF. .„..774 70.Alzheimer’sDisease .. 932 COPDvsAsthma. 618 CommonIssueswithPancreaticEnzymeProducts 776 ^ KeyDrugsthatCanWorsenDementia- -,- 933 ^ 43.TobaccoCessation 629 56.Transplant 779 71.Seizures/Epilepsy 937 TreatmentConsiderationsforTobaccoCessation 631 . TransplantDrugs:What'sUsed.When .785 DrugsthatCanLowertheSeizureThreshold 938 . NicotinePatchAdministration. 632 Vaccine-PreventableIllnessinTransplantRecipients 786 DiastatAcudialDispensing. 939 i HowtoChewNicotineGum.... 632 57. WeightLoss 789 :. AEDCousins 940 ENDOCRINECONDITIONS..634 SSeelleeccttDDrruuggsv-CCoonnddiittiioonnsstthhaattCCaannCCaauusseeWWeeiigghhttGLoasins.......779900 . LTaakmeicYtoaulrSVtaitratemrKinistso:CnoAlEoDrssH!tMeUlpIMStUa4»feUt4y«t.t.U<UIUMUUil„„ 994401 Phenytoin/FosphenytoinAdministration 946 . PrescriptionWeightLossDrugs.AvoidorUseCaution 791 . 44.Diabetes 636 AdjustingPhenytoinDoses 949 . DiagnosticCnteria 638 AEDsHaveaLotofDrugInteractions 949 PAIN/RELATEDCONDITIONS » ComplicationsofDiabetes 639 AEDsareCNSDepressants., 949 AdultTreatmentGoals(ADA)..... 641 58.Pain 796 ' DrugsthatCanRaiseBloodGlucose... 641 . AcetaminophenOverdose — 798 GASTROINTESTINAL . TreatmentAlgonthm. ^ 642 NSAJDsandtheDuctusArteriosus. _799 CONDITIONS•••••••••••••••••a....954 \.. IICnnositnuiaclitneinnCgtroBanatvesedarlIs-nBiosonuluslisn—IPnrsou_dl—iuncts- „. ..666555667 . OOOpppiiioooiiiddd-BAInolldexuregcdyeW.d—aCronninsgtispation 888000882 72.GUlacsetrroDeisseoapsheagealRefluxDisease&Pep.t.ic.956 . KeyDrugsthatCanWorsenGERDSymptoms 957 .:" HMSFaeyuclpelttecoidrtrgosDlsytroeucegCPmseotninhcssaCi(dtNreCisoraeNWnseLTheoredewnlaeeStmrIenBelcelnlocutotdindegGdD)lurucogsTereatment—666665669021 5.9.MCOOoppigmiioormiiaddoiIOnnnvdeMeu.r.icdg.e.orad*sieRneMesTapnnigraaggteoerrmsyeDnetpression(OIRD)Risks 881881118911 7.3.HKCe2oyRnDAsrautngipdsaPwPtiiItohFnoDrem&curDelaaitsaioerndrshAteboasKonrpotwio.n.. 999665609 4:5.SST/eShlxeycortfoDHirduypgDostiahsnyodrroCdidoeinsrmdsitionsthatcan 666645 60.TGnoptuantFormulations _ 828251 ^. DSWerhuleigccshtDtOhraTuCtgastroethRCaeotcCnosamtnipmCaeatiunnsdgefoDriaCrorhnesat.ipation—,—„.„.999676727 ; CLeavuostehHyryopxointheyTraobidleistmColors — _666675 GDrouugtsTtrheaattImncernetaBsaesUicnsc.Acid. .882267 74.IMnafilnatemnamncaetoofrRyeBmoiswsieonl:DCiosmeapasreis.onof 975 . S/SxofHyperthyroidism— 668 CommonCDandUCTreatments 977 . S/SxofThyroidStorm 669 ONCOLOGY 831 75.MotionSickness 983 46.SystemicSteroids& 61.OncologyI:Overview&SideEffect . Scopolamine(TransdermScop)Patch 985 AutoimmuneConditions _ 671 Management .832 : Steroids:LeastPotenttoMostPotent.— — .673 . DosingConsiderationsforSelectHighlyToxicDrugs 835 PHARMACYFOUNDATIONS ^ : ImmunosuppressionfromSteroids 674 ChemoManandMajorToxicitiesof PART2 986 -: TSErereyleathctietnDmgraAutgcousstuTeshIna(DftlaCimlai)nmCaatuiosnewDirtuhgS-ItnedrouicdesdLupus 668724 CHCoyhdmermamotioothnne.CrTahopeRymeAoddtuhjuceenracTptoivyxeDicMrituyeg_dsications.. „..888335788 7.6.MSeeledcticNaattiioonnaSlPaafteietynt&SaQfeutyaGliotyalIsmprovement....998980 . Drug-InducedRaynaud's 686 . Irinotecan(l-Run-To-The-Can) . 846 i DoNotUseAbbreviations 991 62.OncologyII:CommonCancerTypes 77.DrugAllergies&Adverse MALE& FEMALEHEALTH....692 &Treatment 851 DrugReactions... 1000 * . ToReduceDoxorubicinCardiotoxicity 864 IntoleranceorAllergy7 1003 47.Contraception&Infertility — 694 HintsforUnderstandingMonodonalAntibodies 872 DrugsMostCommonlyAssociatedw/Photosensitivity...1004 SelectContraceptiveTypes 699 s DrugsCommonlyAssociatedw/TTP 1004 Severe&RareAdverseEffectsofEstrogen 700 PSYCHIATRICCONDITIONS..878 DrugsCommonlyAssociatedw/SevereSkinReactions...1005 ItnofTenrgtilgiteyrDOruvugslaAtioctnL..ik.•e•••E•44n4*|d4o44g»#4e4nousHormones ..706 63.Depression 880 .. EApPineenpichilnlinneAAlleurtgoy-,InojreNctootr?AUdulm• in«i4s4*t4r4•a»•t•i•o••n•444««••••••• 11000067 48.DrugUseinPregnancy&Lactation 707 . SelectDrugsthatCauseorWorsenDepression4*4444»4444««444881 78.Pharmacokinetics.... .1009 Teratogens:DangerinPregnancy 709 DepressionDiagnosis 881 . DrugAbsorption .1010 49.Osteoporosis,Menopause& AntidepressantsSelectAdverseEffects 885 . DoseAdjustmentsforMichaelisMentenKinetics ...1015 ; TSDeiealesgcnttooFssaitscetoorforOsnasetnedUoCpsooernod_s_iitsionswithOsteoporosisRisk„.777111344 6..4.MSSeAclehOciIztninohgpibthhiteroerBsne-isaKt/AePenpstidyTechphermoessSsisaenptarated. .888988287 7.9.DSPeohleeascrtamDPraousgcistoivwgeeiothnrPoNhmeagriamctisvaecoTgeesntRomeqicuiIrmepAlicctaiotino?n..s 1.01100222033 :. CaDnarudlcgPiuSrmeuvmaenmndtaioVrnyitfaomrOinsDteopor*osisTreatm—ent ..771156 PPMsiecykdciinhcgoatttiihcoenSsBy/emllsliptctAiotnmDtrispusgyscthhoatticCanCause —889953 80.CDoiemtapryleSmuepnptlaermyeMnetds,icNinaetural& 1024 . HormoneTherapy:HealthRisksandAppropnateUse„„722 65.BipolarDisorder 901 . DifferencesBetweenDietarySupplementsandDrugs..1025 50.SexualDysfunction 729 Lithium-NotEasytoInitiate.. 904 81.EmergencyPreparedness,Toxicology DrugsthatCanCauseErectile/SexualDysfunction 730 66.AttentionDeficitHyperactivityDisorder &Antidotes 1033 . PDE-5InhibitorDosingGuide 731 (ADHD) 905 CommonSymptomaticTreatment 1035 51.BenignProstaticHyperplasia(BPH) ...734 . Patient-FriendlyFormulationsforStimulants 906 N-AcetylcysteineTreatment —1036 4444444 InitialManagementofSuspectedOpioidOverdose 1036 s DrugsthatCanWorsenBPH 734 67 AnxietyDisorders 913 52.OveractiveBladder 740 ^ SelectDrugsthatCauseAnxiety.—.— 913 CONTENT LEGEND . AnticholinergicSideEffects.... 742 : SafeUseofBenzodiazepines 916 flU ^» DecreasingRiskofDryMouth .742 ( )=StudyTipGal =KeyDrugGuy PREPARING FOR NAPLEX m i j f CONTENTS CHAPTER 1 PREPARING FOR NAPLEX WITH THE RxPREP COURSE | 3 QUICK GUIDES 113 HOW TO USE THE RxPREP COURSE BOOK | 14 TOP OUTPATIENT DRUGS | 15 TOP INPATIENT DRUGS | 19 TOP OTC DRUGS | 23 REQUIRED FORMULAS | 25 DIAGNOSTIC TESTS I 27 MEDICAL TERMS | 30 COMMON MEDICAL ABBREVIATIONS | 39