I II III Robbins and Cotran PATHOLOGIC BASIS OF DISEASE Seventh Edition VINAY KUMAR MBBS, MD, FRCPath Alice Hogge and Arthur Baer Professor Chairman, Department of Pathology The University of Chicago, Pritzker School of Medicine Chicago, Illinois ABUL K. ABBAS MBBS Chair, Department of Pathology University of California, San Francisco San Francisco, California NELSON FAUSTO MD Chairman, Department of Pathology University of Washington School of Medicine Seattle, Washington A-PDF Split DEMO : Purchase from www.A-PDF.com to remove the watermark With Illustrations by James A. Perkins, MS, MFA ELSEVIER SAUNDERS IV ELSEVIER SAUNDERS An Imprint of Elsevier The Curtis Center 170 S Independence Mall W 300E Philadelphia, Pennsylvania 19106 ROBBINS AND COTRAN PATHOLOGIC BASIS OF DISEASE, 7/E 0-7216-0187-1 International Edition ISBN 0-8089-2302-1 Copyright © 2005, Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier's Health Sciences Rights Department in Philadelphia, PA, USA: phone: (+1) 215 238 7869, fax: (+1) 215 238 2239, e-mail: