CONTENTS DOPAMINERGIC NEURAL GRAFTS AFTER FIFTEEN YEARS: RESULTS AND PERSPECTIVES J.-P. HERMAN and N. D. ABROUS,* CNRS UMR 9941, Laboratoire des Interactions Cellulaires Neuroendocriniennes, Faculté de Médecine Nord, Brd Pierre Dramard, 13916 Marseille Cedex 20, France, and *INSERM U-259, Domaine de Carreire, Rue Camille Saint-Saéns, 33077 Bordeaux Cedex, France TRANSNEURONAL LABELLING OF CNS NEURONS WITH HERPES SIMPLEX VIRUS 37 W. W. BLESSING, Z.-Q. DING, Y.-W. LI, Z. J. GIEROBA, A. J. WILSON,* P. G. HALLSWORTHi } and S. L. WESSELINGH,* *Department of Radiology, Centre for Neuroscience, Flinders University of South Australia 5042, Australia, and *Department of Medicine and Physiology, Infectious Diseases, Centre for Neuroscience, Flinders University of South Australia 5042, Australia FEMALE SEX STEROID HORMONES: FROM RECEPTORS TO NETWORKS TO PERFORMANCE — ACTIONS ON THE SENSORIMOTOR SYSTEM 55 S. S. SMITH, Department of Anatomy, Institute of Neuroscience, Hahnemann University, Philadelphia, PA 19102-1192, U.S.A. NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY STUDIES OF THE BRAIN 87 R. A. KAUPPINEN* and S. R. WILLIAMS,+ *NMR Research Group, Department of Biochemistry and Biotechnology, A.I. Virtanen Institute, University of Kuopio, Kuopio, Finland, and *Department of Biophysics, The Institute of Child Health, London, U.K. NEUROGENIC AND MYOGENIC REGULATION OF SKELETAL MUSCLE FORMATION: A CRITICAL RE-EVALUATION 119 I. S. McLENNAN, Department of Anatomy and Structural Biology, The University of Otago, P.O. Box 913, Dunedin, New Zealand POSSIBLE MECHANISMS OF ACTION OF (-) DEPRENYL AND OTHER MAO-B INHIBITORS IN SOME NEUROLOGIC AND PSYCHIATRIC DISORDERS 141 M. D. BERRY,* A. V. JUORIO and I. A. PATERSON, Neuropsychiatric Research Unit, A114 Medical Research Building, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 0WO POLYSYNAPTIC INTEGRATION OF GLUTAMATERGIC AND DOPAMINERGIC SIGNALS IN THE STRIATUM 163 R. KOTTER, Department of Anatomy and Structural Biology and The Neuroscience Research Centre, University of Otago, Medical School, Dunedin, New Zealand ill iv CONTENTS CENTRAL NEURAL MECHANISMS MEDIATING EXCITATION OF SYMPATHETIC NEURONS BY HYPOXIA 197 M.-K. SUN and D. J. REIS, Department of Neurology and Neuroscience, Cornell University Medical College, 411 East 69th Street, New York, NY 10021, U.S.A. THE PSYCHOLOGY OF PERSEVERATIVE AND STEREOTYPED BEHAVIOUR 221 R. M. RIDLEY, Department of Experimental Psychology, Downing Street, Cambridge CB2 3EB, U.K. ARE YOU USING NEURONAL DENSITIES, SYNAPTIC DENSITIES OR NEUROCHEMICAL DENSITIES AS YOUR DEFINITIVE DATA? THERE IS A BETTER WAY TO GO 233 D. E. OORSCHOT, Department of Anatomy and Structural Biology, and The Neuroscience Research Centre, University of Otago, P.O. Box 913, Dunedin, New Zealand EARLY DEVELOPMENTAL PATTERNS AND MECHANISMS OF AXONAL GUIDANCE OF SPINAL INTERNEURONS IN THE CHICK EMBRYO SPINAL CORD 249 H. YAGINUMA,* T. SHIGA# and R. W. OPPENHEIM,# *Department of Anatomy, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba 305, Japan, ‘Department of Anatomy, Yamagata University School of Medicine, Yamagata 990-23, Japan, and {Department of Neurobiology and Anatomy, and Neuroscience Program, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157, U.S.A. GONADAL HORMONES AS PROMOTERS OF STRUCTURAL SYNAPTIC PLASTICITY: CELLULAR MECHANISMS 279 L. M. GARCIA-SEGURA,* J. A. CHOWEN,* A. PARDUCZ#+ and F. NAFTOLIN,¢# *Instituto Cajal, C.S.1.C., 28002 Madrid, Spain, tInstitute of Biophysics, Biological Research Center, Hungarian Academy of Sciences, H-6701 Szeged, Hungary, and {Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, U.S.A. NEURAL GRAFT AUGMENTATION THROUGH CO-GRAFTING: IMPLANTATION OF CELLS AS SOURCES OF SURVIVAL AND GROWTH FACTORS 309 T. J. COLLIER* and J. E. SPRINGER,?* * Department of Neurobiology and Anatomy, University of Rochester School of Medicine, Rochester, NY 14642, U.S.A., and *Department of Neurology, Hahnemann University, School of Medicine, Philadelphia, PA 19102, U.S.A. ELECTROPHYSIOLOGICAL AND METABOLIC INTERACTIONS BETWEEN AXONS AND GLIA IN CRAYFISH AND SQUID 333 E. M. LIEBERMAN,* P. T. HARGITTAI* and R. M. GROSSFELD,?+ *Department of Physiology, School of Medicine, East Carolina University, Greenville, NC 27858, U.S.A., and *Department of Zoology and Physiology Program, North Carolina State University, Raleigh, NC 27695-7617, U.S.A. CONTENTS Vv THE HIGH AFFINITY UPTAKE SYSTEM FOR EXCITATORY AMINO ACIDS IN THE BRAIN 377 N. C. DANBOLT, Anatomical Institute, University of Oslo, P.O. Box 1105, Blindern, N-0317, Oslo, Norway GENE EXPRESSION AND FUNCTION OF INTERLEUKIN 1, INTERLEUKIN 6 AND TUMOR NECROSIS FACTOR IN THE BRAIN 397 B. SCHOBITZ,* E. RON DE KLOET? and F. HOLSBOER,* *Max Planck Institute of Psychiatry, Clinical Institute, Munich, Germany, and +Leiden-Amsterdam Center for Drug Research, Division of Medical Pharmacology, Leiden University, The Netherlands DOES THE FUNCTION OF REM SLEEP CONCERN NON-REM SLEEP OR WAKING? 433 J. H.B ENINGTON* and H. C. HELLER,** *Department of Psychiatry, UCLA School of Medicine, Los Angeles, CA 90024, U.S.A. and *+Department of Biological Sciences, Stanford University, Stanford, CA 94305, U.S.A. RELEASE-REGULATING PRESYNAPTIC HETEROCARRIERS 451 G. BONANNO and M. RAITERI, Istituto di Farmacologia e Farmacognosia, Universita di Genova, Viale Cembrano 4, 16148 Genova, Italy THE NEUROPROTECTIVE ACTIONS OF CHLORMETHIAZOLE 463 A. R. GREEN and A. J. CROSS, Astra Neuroscience Research Unit, 1 Wakefield Street, London WCIN IPJ, U.K. THE HIPPOCAMPUS: A BIOLOGICAL MODEL FOR STUDYING LEARNING AND MEMORY 485 Y. SHEN,7 S. M. SPECHT,# I. DE SAINT GHISLAINS§ and R. LI, +Experimental Therapeutics Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, U.S.A., {Department of Psychology, Lebanon Valley College, Annville, PA 17003, U.S.A., $Neuropsychiatry Branch, National Institute of Mental Health, National Institute of Health, Neuroscience Center at St Elizabeth’s, Washington, DC 20032, U.S.A., and ||Department of Psychiatry, University of Louisville, Medical School, Louisville, KY 40292, U.S.A. FUNCTIONS OF BRAIN-DERIVED NEUROTROPHIC FACTOR, INSULIN-LIKE GROWTH FACTOR-1 AND BASIC FIBROBLAST GROWTH FACTOR IN THE DEVELOPMENT AND MAINTENANCE OF DOPAMINERGIC NEURONS 497 K. D. BECK, Genentech Inc., Neuroscience, 460 Point San Bruno Blvd, South San Francisco, CA 94080, U.S.A. vi CONTENTS CELL MEMBRANE BIOCHEMISTRY AND NEUROBIOLOGICAL APPROACH TO BIOMAGNETISM M. J. AZANZA* and A. DEL MORAL,? *Instituto de Bioelectromagnetismo “Alonso de Santa Cruz”, Departamento de Ciencias Morfoldégicas, Facultad de Medicina, Universidad de Zaragoza, 50009 Zaragoza, Spain, and *Laboratorio de Magnetismo, Departamento de Fisica de Materia Condensada and ICMA, Universidad de Zaragoza and Consejo Superior de Investigaciones Cientificas, 50009 Zaragoza, Spain