Amino Acid/Metabolics Product Category: Amino Acid/Metabolics Calcilo XD® Cyclinex®-1 Cyclinex®-2 Glutarex®-1 Glutarex®-2 Hominex®-1 Hominex®-2 I-Valex®-1 I-Valex®-2 Ketonex®-1 Ketonex®-2 Phenex®-1 Phenex®-2 Pro-Phree® Propimex®-1 Propimex®-2 ProViMin® RCF® Tyrex®-1 Tyrex®-2 For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 11/24/2015 1-800-227-5767 Metabolic Product Category: Metabolic Calcilo XD® Cyclinex®-1 Cyclinex®-2 Glutarex®-1 Glutarex®-2 Hominex®-1 Hominex®-2 I-Valex®-1 I-Valex®-2 Ketonex®-1 Ketonex®-2 Phenex®-1 Phenex®-2 Pro-Phree® Propimex®-1 Propimex®-2 ProViMin® RCF® Tyrex®-1 Tyrex®-2 For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 11/24/2015 1-800-227-5767 Calcilo XD® Low-Calcium/Vitamin D-Free Infant Formula With Iron Product Information: Calcilo XD® For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 1 of 4 Calcilo XD® Low-Calcium/Vitamin D-Free Infant Formula With Iron l Nutrition support of infants with hypercalcemia, as may occur in infants with Williams syndrome, osteopetrosis, and primary neonatal hyperparathyroidism, and when a low-calcium, vitamin D-free formula is needed. l No vitamin D. l Use under medical supervision. l The only commercially available formula for the management of hypercalcemia in infants. l Nutritionally complete—when prepared as directed, meets the American Academy of Pediatrics Committee on Nutrition recommendations for all nutrients including vitamins and minerals except calcium, vitamin D and phosphorus. l Only a minimal amount of calcium (15 mg/100 g powder; 2.9 mg/100 Cal). l L-carnitine (7 mg/100 g) and taurine (35 mg/100 g). l Eliminates the need to prepare a modular formula. l Kosher. l Halal. l Lactose-free. l Gluten-free. Safety Precautions l Must be given only to infants whose calcium and/or vitamin D intake must be severely restricted, as in hypercalcemia, and who are under strict medical supervision. Calcium, vitamin D and phosphorus requirements should be determined by appropriate laboratory tests. This formula does not supply the minimum recommended intake of calcium, vitamin D or phosphorus for normal infants. l Not for IV use. l Never use a microwave oven to warm formula. Serious burns can result. l Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor. Ingredients Powder Unflavored: Corn Syrup, Coconut Oil, Corn Oil, Whey Protein Concentrate, Sodium Caseinate. Less than 1% of the Following: Potassium Phosphate, Magnesium Chloride, Potassium Chloride, Potassium Citrate, Ascorbic Acid, m-Inositol, Potassium Hydroxide, Salt, Choline Chloride, Ferrous Sulfate, Taurine, Zinc Sulfate, L- Carnitine, d-Alpha-Tocopheryl Acetate, Niacinamide, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, and Cyanocobalamin. Allergens: Contains milk ingredients. Availability List Number Item 53328 Calcilo XD Powder / 13.2-oz (375-g) can / 6 ct For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 2 of 4 Calcilo XD® Low-Calcium/Vitamin D-Free Infant Formula With Iron Nutrition Information - Powder Unflavored   100 Cal 100 g powder   Value Value Protein, % Cal 9 9 Protein Source Whey Protein Concentrate, Sodium Caseinate Whey Protein Concentrate, Sodium Caseinate Fat, % Cal 50 50 Fat Source Coconut and Corn Oils Coconut and Corn Oils Carbohydrate, % Cal 41 41 Carbohydrate Source Corn Syrup Corn Syrup Osmolality, mOsm/kg H2O 190 190 Volume, mL 148   Protein, g 2.2 11.4 Fat, g 5.6 28.7 Carbohydrate, g 10.2 52.3 Water, g 134 2.5 Linoleic Acid, mg 1300 6660 Calories 100 513 Potential Renal Solute Load, mOsm 18 94 Vitamin A, IU 300 1540 Vitamin D, IU 0 0 Vitamin E, IU 1.9 10 Vitamin K, mcg 8 41 Thiamin (Vitamin B1), mcg 100 513 Riboflavin (Vitamin B2), mcg 150 770 Vitamin B6, mcg 60 310 Vitamin B12, mcg 0.3 1.3 Niacin, mcg 1050 5400 Folic Acid (Folacin), mcg 15 77 Pantothenic Acid, mcg 450 2300 Biotin, mcg 4.5 23 Vitamin C, mg 9 46 Choline, mg 12 62 Inositol, mg 24 123 Calcium, mg 2.9 15 Phosphorus, mg 25 128 Magnesium, mg 6 31 Iron, mg 1.8 9.2 Zinc, mg 0.8 3.8 Manganese, mcg 5 26 Copper, mcg 90 460 Iodine, mcg 6 31 Sodium, mg 24 125 For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 3 of 4 Calcilo XD® Low-Calcium/Vitamin D-Free Infant Formula With Iron Nutrition Information - Powder Unflavored   100 Cal 100 g powder   Value Value Sodium, mEq 1.0 5.4 Potassium, mg 82 420 Potassium, mEq 2.1 10.7 Chloride, mg 57 292 Chloride, mEq 1.6 8.2 Preparation Directions for Preparation and Use: Use Only As Directed by a Physician Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use. l Wash your hands, surfaces and utensils. l Pour prescribed amount of water into a clean bottle (see mixing guide). l Add 1 unpacked level scoop (8.6 g) to each 2 fl oz of water l Return dry scoop to can. l Cap bottle; shake well; attach nipple. l Once feeding begins, use within 1 hour or discard. Mixing Guide Measure Water Add scoop(s) ofunpacked level Finished Bottle powderusing enclosed scoop (approx) 2-fl-oz 1 scoop (8.6 g) 2 fl oz 4-fl-oz 2 scoops 4 fl oz 6-fl-oz 3 scoops 6 fl oz l To make a larger amount of formula at standard measuring cup, add 1 unpacked, level cup (NOT the enclosed scoop) of powder (105 g) to 24 fl oz of water. Yields approximately 26 fl oz of formula. l To maintain freshness, pour prepared formula into individual feeding bottles, cap and store in refrigerator. l Prepared formula should not be left unrefrigerated. l When mixed as directed, the contents of one can (375 g) will make approximately 96 fl oz of formula at 20 Cal/fl oz. Storage & Handling Powder l Once mixed, store bottles or container in refrigerator and feed to baby or child within 24 hours l Store unopened or opened can at room temperature; avoid extreme temperatures. l Use opened can contents within 1 month. For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 4 of 4 Cyclinex®-1 Amino Acid-Modified Infant Formula With Iron Product Information: Cyclinex®-1 For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 1 of 5 Cyclinex®-1 Amino Acid-Modified Infant Formula With Iron l Nutrition support of infants and toddlers with a urea cycle disorder, gyrate atrophy or HHH syndrome. l Nonessential amino acid-free. l Use under medical supervision. l Nonessential amino acid-free to decrease the ingestion of waste nitrogen. l L-carnitine (190 mg/100 g) and taurine (40 mg/100 g) to help supply amounts normally found in human milk and foods of animal origin. l Approximately 43% of energy as fat to help achieve acceptable formula osmolality. l 6.9% of energy as linoleic acid. l Nutrient profile specifically designed for infants and toddlers. l When fed according to the Abbott Nutrition Support Protocols, provides adequate amounts of all nutrients. l Additional vitamins and minerals to compensate for nutrient losses due to nitrogen-scavenger medications. l Halal. l Lactose-free. l Gluten-free. Safety Precautions l Give only to infants and toddlers with a proven urea cycle disorder, gyrate atrophy or HHH syndrome who are under medical supervision. Must be supplemented with protein and fluid in prescribed amounts to completely meet protein and water requirements. l Not intended as a sole source of nutrition. l Not for IV use. l Do not boil mixture or use terminal sterilization. l Never use a microwave oven to warm formula. Serious burns can result. l Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor. l To meet the nutrient needs of the infant or child, infant formula, breast milk or additional food choices must be given to supply protein requirements. These may be added to the Cyclinex-1 mixture or prepared separately as instructed. Depending on the specific needs of each patient, preparation will vary as prescribed by physician. Ingredients Powder Unflavored: Corn Syrup Solids, High Oleic Safflower Oil, Coconut Oil, Soy Oil, L-Leucine. Less than 2% of the Following: L-Lysine Acetate, Calcium Phosphate, L-Valine, DATEM, L-Isoleucine, Potassium Phosphate, L-Tyrosine, L-Threonine, L-Phenylalanine, Sodium Citrate, Potassium Citrate, Magnesium Chloride, L- Cystine Dihydrochloride, L-Histidine, L-Methionine, L-Tryptophan, Calcium Carbonate, Ascorbic Acid, L- Carnitine, Choline Chloride, Taurine, m-Inositol, Ferrous Sulfate, Zinc Sulfate, Ascorbyl Palmitate, dl- Alpha-Tocopheryl Acetate, Niacinamide, Mixed Tocopherols, Calcium Pantothenate, Salt, Cupric Sulfate, Thiamine Chloride Hydrochloride, Manganese Sulfate, Vitamin A Palmitate, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Beta-Carotene, Potassium Iodide, Biotin, Phylloquinone, Sodium Selenate, Chromium Chloride, Sodium Molybdate, Vitamin D3, and Cyanocobalamin. Availability List Number Item 51144 Cyclinex-1 Powder / 14.1-oz (400-g) can / 6 ct For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 2 of 5 Cyclinex®-1 Amino Acid-Modified Infant Formula With Iron Nutrition Information - Powder Unflavored   100 Cal 100 g powder   Value Value Protein Equivalent Source L-Amino Acids L-Amino Acids Fat Source High Oleic Safflower, Coconut and Soy Oils High Oleic Safflower, Coconut and Soy Oils Carbohydrate Source Corn Syrup Solids Corn Syrup Solids Osmolality, mOsm/kg H2O* 275 275 Protein Equivalent, g 1.5 7.5 Fat, g 4.9 24.6 Carbohydrate, g 11.2 57.0 Linoleic Acid, mg 765 3900 Linolenic Acid, mg 74 375 L-Carnitine, mg 37 190 Calories 100 510 Potential Renal Solute Load, mOsm 19.2 98 Vitamin A, IU 311 1600 Vitamin A, mcg RE 94 480 Vitamin D, IU 59 300 Vitamin D, mcg 1.5 7.5 Vitamin E, IU 3 17 Vitamin E, mg alpha-TE 2.2 11.4 Vitamin K, mcg 11.7 60 Thiamin (Vitamin B1), mcg 392 2000 Riboflavin (Vitamin B2), mcg 196 1000 Vitamin B6, mcg 167 850 Vitamin B12, mcg 1.1 5.6 Niacin, mcg 2353 12000 Niacin, mg NE 3.2 16.7 Folic Acid (Folacin), mcg 49 250 Pantothenic Acid, mcg 1529 7800 Biotin, mcg 14.7 75 Vitamin C, mg 11.8 60 Choline, mg 19.6 100 Inositol, mg 9.8 50 Calcium, mg 127 650 Calcium, mEq 6.4 32.4 Phosphorus, mg 89 455 Magnesium, mg 10.8 55 Iron, mg 2.0 10 Zinc, mg 1.9 9.5 Manganese, mcg 98 500 Copper, mcg 245 1250 For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. Columbus, OH 43219-3034 Updated 10/2/2015 1-800-227-5767 3 of 5 Cyclinex®-1 Amino Acid-Modified Infant Formula With Iron Nutrition Information - Powder Unflavored   100 Cal 100 g powder   Value Value Iodine, mcg 15.7 80 Selenium, mcg 4.9 25 Chromium, mcg 2.4 12 Molybdenum, mcg 2.6 13 Sodium, mg 42.2 215 Sodium, mEq 1.8 9.4 Potassium, mg 149 760 Potassium, mEq 3.8 19.4 Chloride, mg 76.5 390 Chloride, mEq 2.2 11.0 Powder Unflavored Footnotes & References Per 100 Cal *Prepared at 20 kcal/oz. Per 100 g powder *Prepared at 20 kcal/oz. Preparation Directions for Preparation and Use: Use Only As Directed by a Physician Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use. l Wash your hands, surfaces and utensils. l Pour prescribed amount of water into a clean container. l Add prescribed amount of Cyclinex-1 powder (and other ingredients if recommended). l Shake well for 10-15 seconds; if using a blender, mix no more than 5 seconds. l Pour mixture into clean feeding bottles or container; cap. l Once feeding begins, use within 1 hour or discard. Approximate Weights for Unpacked, Level U.S. Standard Dry Household Measures for Powder* Household Measure (US) Weight (g) 1 Tbsp 8 1/4 Cup 30 1/3 Cup 40 1/2 Cup 60 1 Cup 120 * For most accurate results, Cyclinex-1 should be weighed on a scale that reads in grams. For more information, contact your Abbott Nutrition Representative or visit www.abbottnutrition.com Abbott Nutrition Abbott Laboratories © 2015 Abbott Laboratories Inc. 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