JAFES Journal of the ASEAN Federation of Endocrine Societies Volume 30 Number 2 ISSN 0857-1074 November 2015 Proceedings of the 18th AFES Congress 2015 The Biennial Scientific Meeting of the ASEAN Federation of Endocrine Societies The statements and opinions expressed in this publication are those of the individual authors and do not necessarily reflect the views of the Malaysian Endocrine and Metabolic Society (MEMS). MEMS, together with all its agents and suppliers, are not responsible or liable in any way for the currency of the information, for any errors, omissions or inaccuracies, or for any consequences arising therefrom. With respect to any drugs mentioned, the reader is advised to refer to the appropriate medical literature and the product information currently provided by the manufacturer to verify appropriate dosage, method and duration of administration, and other relevant information. In all instances, it is the responsibility of the treating physician or other healthcare professional, relying on independent experience and expertise, as well as knowledge of the patient, to determine the best treatment for the patient. Copyright © December 2015 by the Malaysian Endocrine and Metabolic Society (MEMS). All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, posted on the Internet, or transmitted in any form, by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission of the publisher. 003 | CONTENTS AFES INVESTIGATOR AWARD (AIA) ABSTRACT LISTING AFES INVESTIGATOR AWARD (AIA) ABSTRACTS 041 AIA 1 Evaluation of Beta Cell Dysfunction by Mixed-Meal Tolerance Test Among Vietnamese with Newly Diagnosed Type 2 Diabetes Van Phan Thi Tuong, Khanh Tran Quang University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam 042 AIA 2 Modifying Effect of Body Mass Index on Survival in Elderly Type 2 Diabetic Patients - Hong Kong Diabetes Registry Kitty Cheung, Jiang Guozhi, Jenny Lee, Andrea Luk, Alice Kong, Risa Ozaki, Ronald Ma, Francis Chow, Juliana Chan, So Wing Yee Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR 043 AIA 3 Genetics of Diabetes: The Variant of Transcription Factor 7-Like 2 (TCF7L2) Gene and the Prediction of Diabetes Risk in Diabetic Families Dr Abbasali Palizban Department of Clinical Biochemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Iran. 044 AIA 4 MODY 2 Diabetes: 3 Years of Follow Alla Ovsyannikova, Oksana Rymar, Vladimir Maximov, Elena Voropaeva, Mikhail Voevoda Federal State Budgetary Scientific Institution “Scientific Research Institute of Therapy and Preventive Medicine” 045 AIA 5 The Development of a Risk Score in Predicting Hypoglycaemia Admissions for Patients with Type 2 Diabetes Mellitus Kurumbian Chandran, Yu Weichang, Christine Wu, Darren Seah Ee-Jin, Matthias Paul Toh Han Sim Ng Teng Fang General Hospital, Singapore; National Healthcare Group, Singapore; National Healthcare Group Polyclinics, Singapore 046 AIA 6 Free 25-Hydroxyvitamin D Levels, Polymorphism of Viatmin D Binding Protein Gene and Risk for Gestational Diabetes Mellitus Natthinee Charatcharoenwitthaya1, Charintip Somprasit2, Athita Chanthasenanont2, Laor Chailurkit3, Suwannee Chanprasertyothin3, Boonsong Ongphiphadhanakul3 1Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Thammasat University, Thailand; 2Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Thailand; 3Endocrinology and Metabolism, Department of Medicine, Ramathibodi Hospital, Mahidol University, Thailand 004 | CONTENTS AFES INVESTIGATOR AWARD (AIA) ABSTRACT LISTING 047 AIA 7 Predictors of Secondary Intervention in Surgically Resected Non-Functioning Pituitary Adenoma Jeyakantha Ratnasingam1,2, Benjamin Ong3,4, Anthony Russell2,4, Warrick Inder2,4, Ken KY Ho2,4 1Endocrine Unit, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur, Malaysia, 2Department of Diabetes and Endocrinology, Princess Alexandra Hospital, Brisbane, Queensland, Australia, 3Department of Diagnostic Radiology, Princess Alexandra Hospital, Brisbane, Queensland, Australia, 4School of Medicine, University of Queensland, Australia 048 AIA 8 CYP11B2, CYP17A1 and KCNJ5 Protein Expression in Aldosterone-producing Adenomas (APA) with or without CACNA1D Somatic Mutations Elena Azizan, Norlela Sukor, Nor Azmi Kamaruddin, Isa Mohamed Rose, Tan Geok Chin The National University of Malaysia (UKM) Medical Centre 049 AIA 9 Long Sleep Duration is Associated with Insulin Resistance Independently of Obesity in Korean Non-Diabetic Adults Ki Dong Ko, Kyoung Kon Kim, Heuy Sun Suh, In Cheol Hwang Department of Family Medicine, Gachon University Gil Medical Center, Republic of Korea 050 AIA 10 Dietary penta-O-galloyl-α-D-glucose (PGG) Reduces Blood Glucose and Triglyceride in Obese Mice and Expression of PPARγ, C/EBPα, and Induces p21-mediated G1 Phase Cell Cycle Arrest and Inhibits Adipogenesis in 3T3-L1 Preadipocytes Ahmed Malki1, Xueqing Liu2,3, Yanyan Cao2,4,5, Yunsheng Li2, Yanrong Qian2,3,5, Xuan Wang2,4,5, Xiaozhuo Chen2-6 1Department of Health Sciences, Biomedical Sciences Program, Faculty of Science, College of Arts and Sciences, Qatar University, Doha, Qatar; 2Edison Biotechnology Institute, 3Department of Chemistry and Biochemistry 4Department of Biologic Science, 5Molecular and Cellular Biology Program and 6Department of Biomedical Sciences, Ohio University, Athens Ohio 45701 051 AIA 11 Thyroid Stimulating Hormone Receptor Gene Intron 1 and Regulatory T Cells are Risk Factor of Relapse in Graves Disease Fatimah Eliana1, Pradana Suwondo2, Asmarinah2, Alida Roswita Harahap2, Joedo Prihartono2, Tjokorda Gde Dalem Pemayun3 1YARSI University, 2University of Indonesia, 3Diponegoro University 005 | CONTENTS ORAL (O) ABSTRACT LISTING ORAL (O) ABSTRACTS 052 O1 Prospective Study Suggests that Central Arterial Stiffness Independently Predicts Albuminuria Progression in Asians with Type 2 Diabetes Lim Su Chi, Zhang Xiao, Li Na, Liu Jian Jun, Angela MC Moh, Su Chang, Serena KM Low, Tavintharan Subramaniam, Yeoh Lee Ying, Sum Chee Fang Diabetes Centre, Clinical Research Unit & Department of Medicine, Khoo Teck Puat Hospital, Singapore 053 O2 Single Nucleotide Polymorphism at +45 T>G of the Adiponectin Gene and Plasma Adiponectin Level in Type 2 Diabetes Mellitus Khin Thin Yu, Kyu Kyu Maung, Theingi Myint, Khin Win Sein, Ko Ko, Thein Myint Myanmar Society of Endocrinology and Metabolism (MSEM) 054 O3 Incidence of Decreased Glomerular Filtration Rate and Associated Risk Factors in Patients with Type 2 Diabetes Phat Ma Tung, Khue Nguyen Thy University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam 055 O4 Microvascular & Macrovascular Complications in Young Onset Type 2 Diabetes in a Tertiary Health Institution in Malaysia in Comparison with Type 1 Diabetes Patients (MiMaCom) Lim Kim Piow, Foo Siew Hui, Liew Kean Yew, Kavitha Arumugam, Nurafna Mohd Jaafar, Choo Yung Zhuang, Wong Yen Shen Endocrine Unit, Department of Medicine, Selayang Hospital, Selangor, Malaysia 056 O5 Association of Metabolic Syndrome with Non-Alcoholic Fatty Liver Disease in Type 2 Diabetes Kuhu Roy, Uma Iyer, Rumin Shah, Tushar Vaishnav Department of Foods and Nutrition, Faculty of Family and Community Sciences, The Maharaja Sayajirao University of Baroda, Vadodara-390007, Gujarat, India. 057 O6 Use of Continuous Glucose Monitoring in Patients with Diabetic Kidney Disease with Suboptimal Glycemic Control Ester Yeoh, Sharon Fun, Julia Tong, Lim Boon Khim, Tavintharan S., Sum Chee Fang, Yeoh Lee Ying, Lim Su Chi Khoo Teck Puat Hospital, 90 Yishun Central, Singapore 768828 058 O7 Prognostic Factors in Patients Hospitalised with Diabetic Ketoacidosis Manish Gutch, Sukriti Kumar, Syed Mohd Razi, Abhinav Gupta, Keshav Kumar Gupta Department of Endocrinology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India; Department of Radio diagnosis, SGPGI, Lucknow, Uttar Pradesh, India 006 | CONTENTS ORAL (O) ABSTRACT LISTING 059 O8 Glycemic Variability Among Older Adults with Type 2 Diabetes Tong Chin Voon, Nurain Mohd Noor, Masni Mohamad, Zanariah Hussein Endocrine Unit, Department of Medicine, Hospital Putrajaya, Malaysia 060 O9 Glycemic Indices of Traditional Javanese Foods in the Healthy State and Type 2 Diabetes Teky Widyarini, Supriyanto Kartodarsono, Sugiarto, Eva Niamuzisilawati Endocrinology Division, Internal Medicine Department, Faculty of Medicine Sebelas Maret University- Dr. Moewardi Hospital Surakarta 061 O10 Effect of Cosmos Caudatus (Ulam Raja) on Glycemic and Cardiovascular Risk Factors in Type 2 Diabetic Patients: A Randomized Controlled Trial Cheng Shi-Hui, Amin Ismail, Joseph Anthony, Ng Ooi Chuan, Azizah Abdul Hamid, Barakatun Nisak Mohd Yusof Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia; Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, Malaysia; Department of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, Selangor, Malaysia. 062 O11 Correlation of Phospholipase (sPLA2 IIA) Enzime’s Level and Severity of Diabetic Renal Disease in Type 2 Diabetic Patients Harli Amir Mahmudji1, R. Bowo Pramono2, Hemi Sinorita2, M. Robikhul Ikhsan2 1Internal Medicine – Prof. dr. Soeroyo Mental Health Hospital, Magelang; 2Division of Endocrinology – Internal Medicine, dr. Sardjito Hospital, Yogyakarta 063 O12 Incidence of Adrenal Insufficiency and its Relation to Mortality in Patients with Septic Shock Manish Gutch, Sukriti Kumar, Syed Mohd Razi, Abhinav Gupta, Keshav Kumar Gupta Department of Endocrinology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India; Department of Radio diagnosis, SGPGI, Lucknow, Uttar Pradesh, India 064 O13 A Descriptive Review of Patients Suspected with Primary Aldosteronism at The Medical City Hospital Philippines (2000-2015) Patrick James Co, Ruben Kasala, Pacheco Elizabeth The Medical City Hospital, Section of Endocrinology, Ortigas Avenue, Pasig City, Philippines 065 O14 Factors Associated with Adrenal Insufficiency Among Medical Admissions in Hospital Sungai Buloh Ida Ilyani Adam, Nordiana Nordin, Sharimilla Shanugam Internal Medicine Department, Hospital Sungai Buloh, Selangor, Malaysia 007 | CONTENTS ORAL (O) ABSTRACT LISTING 066 O15 Serum Zinc and Copper in Hyperthyroidism Mohammad-Hasan Khadem-Ansari, Sahar Godratizadeh, Yousef Rasmi Department of Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran 067 O16 Prevalence of Non Alcoholic Fatty Liver Disease in Non Obese Hypothyroid North Indian Subjects Tanvi Raghuvanshi, Sandeep Garg, Sunita Aggarwal, Ved Prakash Ghilley Department of Medicine, Maulana Azad Medical College, New Delhi, India 068 O17 Hipothyroidsm Animal Model Using Caprine Thyroglobulin (cTg) Dyah Kinasih Wuragil, Dyah Ayu Oktavianie, Mohammad Noer DliyaulHaq, Aulanni’am Aulanni’am, Agung Pramana Warih Marhendra Brawijaya University, Indonesia 069 O18 Role of Radiofrequency Ablation for the Treatment of Benign Thyroid Nodule; An Experience from Banda Aceh-Indonesia Hendra Zufry, Krishna Wardhana Sucipto Division of Endocrinology, Metabolism & Diabetes, Thyroid Center, Department of Internal Medicine, College of Medicine, Syiah Kuala University; Dr. Zainoel Abidin General Teaching Hospital, Banda Aceh, Indonesia 070 O19 Subchronic Inhalation Exposure of Transfluthrin on Thyroid Peroxidase Level in Rattus Novergicus Wistar Strain Herwindo Pudjo Brahmantyo, Djoko Wahono Soeatmadji Endocrine, Metabolic and Diabetes Division of Internal Medicine. Faculty of Medicine, Universitas – Brawijaya, Saiful Anwar Hospital, Malang 071 O20 10-year Probability of Fracture After Bariatric Surgery Based on QCT and DXA Measured BMD Tan Hong Chang, Matthew Tan Zhen-Wei, Muhammad Asyraf Mohd Razali, Pasupathy Shanker, Alvin Eng Kim Hock, Alvin Ng Choong Meng Department of Endocrinology, Singapore General Hospital 072 O21 Single Nucleotide Polymorphism at rs7903146 of Transcription Factor 7-like 2 Gene in Type 2 Diabetic Patients with Sulphonylurea Failure Tet Tun Chit, Tint Swe Latt, Than Than Aye, Kyu Kyu Maung, Aye Thida, Sagawah Phu Myanmar Society of Endocrinology and Metabolism (MSEM) 073 O22 Melatonin Inhibits Adipogenesis in 3T3-L1 Preadipocytes Lee Jeongkun, Choi Jongyun, Lee Hyun, Gim Juyeon, Kim Chi Hyun Department of Biomedical Engineering, College of Health Science, Yonsei University, Wonju, Republic of Korea 008 | CONTENTS ORAL (O) ABSTRACT LISTING 074 O23 Increased Levels of Retinol Binding Protein 4 (RBP4) in Rats with Subchronical Inhalation Exposure of Transfluthrin Rulli Rosandi, Djoko Wahono Soeatmadji Endocrine, Metabolic and Diabetes Division of Internal Medicine, Faculty of Medicine - Universitas Brawijaya, Saiful Anwar Hospital, Malang 075 O24 Correlation Lipoprotein(a) with Fibrinogen Level in T2DM Patients with Overweight and Obese Hermina Novida, Askandar Tjokroprawiro, Ari Sutjahjo, Agung Pranoto, Sri Murtiwi Surabaya Diabetes and Nutrition Centre, Dr. Soetomo Teaching Hospital; Faculty of Medicine Airlangga University, Surabaya, Indonesia 076 O25 Correlation Between Testosterone Level and Erectile Dysfunction Among Male Type 2 Diabetes Patients Nanang Miftah Fajari, Achmad Rudijanto Endocrine, Metabolic and Diabetes sub Division of Internal Medicine Department, Brawijaya University Malang, East Java, Indonesia 077 O26 Insulin Resistance Gene Expression in Malay Women with PCOS Hani fullah Khan, Fazli ana Mansor, Liyan a Ahmad Zamri, Fatin S. Diabetes & Endocrine Unit, CDNRC, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia; Department of Obstetrics and Gynaecology, Cyberjaya University College of Medical Sciences, JalanTeknokrat 3, Cyber 4, 63000 Cyberjaya, Selangor, Malaysia 078 O27 Microsatellite D19S884 Detection in Malay Women with Polycystic Ovary Syndrome Hani fullah Khan, Fazli ana Mansor, Liyan a Ahmad Zamri, Fatin S. Diabetes & Endocrine Unit, CDNRC, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia; Department of Obstetrics and Gynaecology, Cyberjaya University College of Medical Sciences, JalanTeknokrat 3, Cyber 4, 63000 Cyberjaya, Selangor, Malaysia 079 O28 Potensial Effects of Transfluthrin as an Endocrine Disruptor Chemicals on Estrogen, Androgen, and Thyroid Receptors: Insilico Study Djoko Wahono Soeatmadji Division of Diabetes and Endocrinology, Dr. Saiful Anwar Hospital, School of Medicine, Universitas Brawijaya, Malang, Indonesia 080 O29 Clinical and Metabolic Profile of Male-to-Female Transgenders in Zamboanga Peninsula Alex Jr Pang, Jerome Barrera Zamboanga City Medical Center; Ateneo de Zamboanga University; Philippine Council for Research and Health Development; Department of Science and Technology; Zamboanga Consortium for Health and Research and Development 009 | CONTENTS ORAL (O) ABSTRACT LISTING 081 O30 Pattern and Etiological Profile of Short Stature in Northern India Manish Gutch, Sukriti Kumar, Syed Mohd Razi, Abhinav Gupta, Keshav Kumar Gupta, Madhukar Mittal Department of Endocrinology, Lala Lajpat Rai Memorial Medical College, Meerut, Uttar Pradesh, India; Department of Radio diagnosis, SGPGI, Lucknow, Uttar Pradesh, India; Department of Endocrinology, King George’s Medical University UP 082 O31 Prevalence of Metabolic Syndrome among Overweight and Obese Adolescents in Petaling Jaya: Alarming Rate that Needs Immediate Attention Arliena Amin, Asma Omar, Fatimah Harun, Azriyanti Anuar Zaini, Nurshadia Samingan, Noorasekin Saiman, Aisha Fadhilah Abang Abdullah, Muhammad Yazid Jalaludin Department of Paediatrics, Faculty of Medicine, University Malaya, 59100 Kuala Lumpur 083 O32 Clinical Audit of Turner Syndrome Girls on Growth Hormone Therapy in a Paediatric Endocrine Clinic, Malaysia Melissa Nunis, Lim Poi Giok, Ting Tzer Hwu Endocrine Unit, Department of Paediatrics, Paediatric Institute Kuala Lumpur Hospital; Department of Paediatrics, Faculty of Medicine & Health Science, University Putra Malaysia 084 O33 Case Report: A Successful Pregnancy and Delivery in a Patient with Simple Virilizing Congenital Adrenal Hyperplasia Karen SW Leong, LL Wu Paediatric Department, Universiti Kebangsaan Malaysia Medical Centre (UKMMC) 085 O34 Diabetes Self-Care Management among Malaysian Children and Adolescents Noor Shafina Mohd Nor1, Fatimah Harun2, Azriyanti Anuar Zaini2, Muhammad Yazid Jalaludin2,3 1Faculty of Medicine, Universiti Teknologi MARA, Selangor, Malaysia; 2Division of Paediatric Endocrinology, Department of Paediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; 3University Malaya Paediatric and Child Health Research Group, University Malaya, Kuala Lumpur, Malaysia 086 O35 17 Alpha-Hydroxylase Deficiency in a 46,XX Karyotype with Coexistent Mullerian Agenesis and Gonadal Dysgenesis Ma. Vircel Duyongco-Tiu, Claire Carampatana-Jandug, Sheena Buaquina, Albert Chu Chong Hua Hospital, Endocrine Office, 4B wing, Don Mariano Cui St., Cebu City 6000 Philippines 087 O36 Hypoglycemia in Pregabalin: A Case Report Michelle Cornel, Erva Magbanua, Ruby Go Chinese General Hospital And Medical Center 010 | CONTENTS ORAL (O) ABSTRACT LISTING 088 O37 IgG4-Related Hypophysitis Presented with Diabetes Insipidus, a Diagnostic Problem Case Report Hari Hendarto1,2, Imam Subekti1 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine University of Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia; 2Department of Internal Medicine, Faculty of Medicine and Health Science, UIN Syarif Hidayatullah, Jakarta, Indonesia 089 O38 Thyrotoxic Periodic Paralysis Clinical Features in the Cambodian Patients: Report of 16 Cases Sum Satha, Ros Sina, Chea Savuth, Nhem Sophoeun, You Kimyean Department of Internal Medicine “A”, Calmette University Hospital, Cambodia 090 O39 Carcinoid Crisis in a Medullary Thyroid Carcinoma Subashini Rajoo, Azraai Nasruddin, Wan Juani Wan Seman, Zanaria Hussein Endocrine Unit, Department of Medicine, Hospital Putrajaya, Pusat Pentadbiran Kerajaan Persekutuan, Presint 7, 62250 Putrajaya, Malaysia 091 O40 A Comparison of two Cases of Pheochromocytoma with Predominant Neuropsychiatric Manifestations Kristine De Luna, Leilani Mercado-Asis, Allan Baroque Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila 092 O41 Ectopic Pheochromocytoma Localized Through Bilateral Adrenal Venous Sampling with Glucagon Stimulation Kristine De Luna, Leilani Mercado-Asis, Allan Baroque Section of Endocrinology, Diabetes and Metabolism, University of Santo Tomas Hospital, Manila 093 O42 Composite Rhabdoid Features in Adrenocortical Carcinoma with an Unpredictable Natural History: A Case Report and Review of Literature Taweesak Wannachalee, Rungpailin Buranagan, Ananya Pongpaibul Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand 094 O43 A Rare Case of MEN1 with Parathyroid Adenomas, TSH-FSH Secreting Pituitary Macro Adenoma and Pancreatic Neuroendocrine Tumour Lau Bik Kui, Florence Tan Endocrine Unit, Medical Department, Sarawak General Hospital, Kuching, Malaysia 095 O44 Micronodular Pheochromocytoma Joie Dj Isip, Aivind Santiago, Nerissa Ang-Golangco Makati Medical Center