Conjunctival Melanocytic Lesions: Pathological Aspects Raymond Barnhill Institut Curie Paris, France ! Take Home Messages Immutable 1. Always have all information ! 2. Always examine the entire lesion ! 3. Uncertainty in difficult ! melanocytic lesions exists Is This Melanoma? Primary Acquired Melanosis (PAM) vs Melanoma Invasive Melanoma on Extensive PAM (= in situ melanoma) Is this Melanoma? Biphasic/Combined Nevus Mimicking Melanoma Conjunctival Melanocytic Lesions Primary Acquired Melanocytic Melanosis Nevi PAM Melanoma First Take Home Message 1. PAM and Nevi !  Clinical and histological mimics of melanoma !  Precursors of melanoma !  !  Risk factors for melanoma