ee us i s are trd. Plea ke eaert ge bry ins Preliminary Comments, Review of Paall s. ent ed ting filesetbeen acci the NationIanli tNiaatnivoetechnology al typhave ginay orim he ors m terr k, not froographic Committee for the Review of the National Nanotechnology Initiative ooyp Division on Engineering and Physical Sciences er bme t National Research Council p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio PDF file: This new nal; line lengths, wnt version of this pu NatWioansahl iAngctaodne,m Dy. CP.ress About this to the origiuse the pri ee us ii s are trd. Plea es. 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All rights reserved. ginay Printed in the United States of America orim he ors m terr k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us iii s are trd. Plea ke eaert ge bry ins Paall s. ent ed ting filesetbeen acci al typhave The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished ginay scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology orim and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, he ors the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. m terr Dr. Bruce M.Alberts is president of the National Academy of Sciences. k, not froographic AcadTemhey Nofa Sticoineanlc eAs,c aasd ae mpayr aollfe lE onrggainneizeartiinogn owfa osu tessttaanbdliinshge edn ginin e1e9r6s.4 ,I t uisn daeurt otnhoem cohuasr tienr itos fa dthmei nNisatrtaiotinoanl op per bome ty aanddv isiinn gt hteh es efleedcetiroanl goofv eitrsn mmeenmt.b Terhse, sNhaatriionnga lw Aitcha dtheem yN aotfi oEnnalg iAneceardinemg ya lsoof sSpcoiennsocerss ethneg inreeseprionngs ipbriloigtyr afmosr ao original ped, and s aoifm eendg iante emrse.e Dtinr.g W namti.oAn.aWl unlefe idss p, reenscidoeunrta goef st heed uNcaattiioonna la Andc ardeesemayrc ohf, Eanndg irneeceorginngiz.es the superior achievements he ain The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the m tret services of eminent members of appropriate professions in the examination of policy matters pertaining to the ed froeat be annot hcmoeeandlgtihrce asols fci otahnreea ,l p rcuehsbaeliractre.c rTh t,ho ae nb Iden saetndi tuaucdtaevt iiaoscentr.s tDuonr t.d hKeer e fntehndeee trrhae lsI p.gSoohnvisenirben iimlsit eypn rget siavindeden,n tuto po tofh nteh ieNts Ia notsiwotinntu aitlne Ai toicafa tMidveeemd, ityco i onifde eS.nctiiefnyc iesss ubeys iotsf ML files crowever, c the bTrohaed N caotmiomnauln Ritye soeaf rscchie Cncoeu nacnidl wteacsh noorgloagnyiz ewdi tbhy tthhee ANcaatidoenmaly A’sc apduerpmoys eosf oSfc ifeunrcthese riinn g1 9k1n6o wtol eadsgsoec iaantde m Xg, h advising the federal government. Functioning in accordance with general policies determined by the Academy, ed fromattin tNhaet iConoauln Acicl ahdaesm bye coof mEen gtihnee eprriinngc iipna lp roopveirdaitningg s eargveincecsy toof thbeo thg otvheer nNmaetniot,n athl eA pcuabdleimc, ya nodf tShcei esnccieesn tiafnicd atnhde en recomposg-specific forn. eDRnerg.s ienBaerrecurhci neC go Mcuon.Amcilmlb.eurntsit ieasn.d T Dher .C Woumnc.Ail .iWs audlfm ainreis tcehreadir mjoainnt lya nbdy vbiocteh Achcaaidrmemanie, s raensdp etchteiv Ienlsyt,i tuotfe tohfe M Neadtiicoinnael. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us iv s are trd. Plea ke eaert ge bry ins Paall s. ent ed ting filesetbeen acci al typhave ginay orim he ors m terr k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us v s are trd. Plea ke eaert ge bry ins COMMITTEE FOR THE REVIEW OF THE NATIONAL NANOTECHNOLOGY Paall INITIATIVE s. ent ed ting filesetbeen acci SMDAAOMVUIUNDEG BLI EBSETABUWEP,EP UN, NnDiovI,re tMrhswiatyesss oatefc rhWnu Usisencttoisvn eIsnrisnsit,ti ytMu, tCaed hoiasfoi rTnechnology al typhave RSHOIBRELRETYO C CHAIARN, PGr,i nUcnetiovne rUsintyiv oefr sCitaylifornia, Davis originmay DENIS GRAY, North Carolina State University he ors MICHAEL HELLER, University of California, San Diego m terr KARL HESS, Beckman Institute, University of Illinois k, not froographic GLTIYEMRNOANTL JHDEYL I IASNF.JSREKANI,TK SESu,, n NNsoharinntoheG CCraoarmnosl uiCnlotaar nSpttosartaet iUonniversity op er bome ty PCHHIELRIPR YK UMEUKRERSA, HYe, wLluectte-nPta Tckeacrhdnologies p ao ps LYDIA SOHN, Princeton University original ed, and TTO.SM.S UTDHAERISS, HIBAMN, Materials Modification, Inc. he ain om te ret Committee Staff ed frat bnnot Michael Davey, Study Director ea Rebecca Short, Administrative Assistant es crer, c Dorothy Zolandz, Responsible Staff Officer L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us vi s are trd. Plea ke eaert ge bry ins Paall s. ent ed ting filesetbeen acci al typhave ginay orim he ors m terr k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us PREFACE vii s are trd. Plea ke eaert ge bry ins Preface Paall s. ent ed ting filesetbeen acci original typmay have NatioTnhails E sctuodnyo mhiacd Citosu onrciigl ianns di nt hien floeramdearls hdiipsc oufs stihoen Ns abteitowneael nR eCsleinartochn Cadomuninciisl t(rNatRioCn) .s tTafhfe osft utdhye dWidh inteo tH boeugsine he ors until more than a year after those discussions, since the multiple agencies involved in the National m terr Nanotechnology Initiative (NNI) had to agree on the statement of task for the review and on a mechanism for k, not froographic sahdadrrienTsgsh etth hceeo tmeaxsmkpi,e tnatenseed . w tOhaesn ccceoh matrhmgee idtstt euwed iymth e wrte afssop rof otnhrdemi nfaiglrl sytto t iitnmhietei af ootenlld oA, wiunign uJgsu tqn u3ee0 2s at0ino0dn1 s,3 :1th, e2 0N0R1.C assembled a committee to op oy er bme t (cid:127) Does the NNI research portfolio address the relevant skills and knowledge to assure that the United p ao ps States will fully benefit from the new technology? Is the balance of the research portfolio appropriate? original ed, and (cid:127) Athree pthoer tafovlaiiol?a bAler eU .tSh.e rceosorruerccte ss e(ehdu minavne, sitnmfreansttsr ubcetuinrge, manadd efu nnodwin gt)o bperionvgi daep pnlieeedd eadp pirnofprarisatrteulcyt uwreit hfoinr he ain future years (2002–2005 and beyond)? Are partnerships (government-industry-university, international) m tret being used appropriately to leverage the public investment in this area? oe ed frat bnnot (cid:127) iIns vtehset mpeonrttf?o Ilsio t hoef wphrooglera gmresa bteeri nthga nco tohred sinuamte odf itnh es upcahrt sa? way as to maximize the effectiveness of the ea (cid:127) Does the NNI give sufficient consideration to the societal impact of developments in nanotechnology? es crer, c (cid:127) Are the processes for evaluating the effectiveness of the NNI (determination of metrics, milestones, and L filwev so on) appropriate and meaningful? How should the program be evaluated in light of the long-term (10– Mo 20 year) nature of many of its research goals? Xh m g, (cid:127) What are important areas of future investment in specific areas of nanotechnology? een recomposed frong-specific formattinon. esptxruetdesreynNAn ratNseel pdtIpho rierlnoet , cga fortduhamelmefrim slN lrimheRttvaeeCvinee e tcwh ,oo a fsnsa i stnnmhedcane etttt eh ootdebhn iletrlio iygrd a poetfrsiniooircrvsneeti. dtfdoeoi rsad c aqbutuersii,sce itkfoh npifssre eedlwdoimbcitauhicnm kaNe ronyRnt Cr iets hp lbeoer raipted r4feo. r gmsIrth aocimpno,tn. h teTsam ihinnepstrho eaa f tsoshiurzeeme ,sd mti untad hrayeyd.i drdT iethcisioocsmnr di pmtootcii otutmhnme eoe nffnti t nt htaioesl the original work has bation of and other typesettiding styles, for attributiauthoritative version NcdiesnoxooN cpmcAieIuem prmtaiapeinetlendt ninec stedoess i uuxpbieternlasies s np repeeAaseslr a rebifatdteorns dir doem b nftolBri ynoa ,i gn att.rdo de p asuncipcnodesdn c etcmthrilv uaatehtsn lieatyoh g.na eiusTn scghpoo einmn c ceambosnr miooitestfmecf eitainh tlftgeeee seeN r lersNaes lecwIs.aeo iriT lvclbh hebaed,se em cacsoe trm iiettttismhic neaseg ltr a mcattoiegea meeltnihtezidenni angtu sg al tnaoitmndnhd aaa itt t eobsr niesmb uslneecioaumcgremcbrshaesep, rr oosha’fuy ns ted chxa bepne aeN xcrbkatNeimgs Irfe.ioo nTuuainnnnhdgdde epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us PREFACE viii s are trd. Plea eakerte This document is not intended to comprehensively answer the six questions in the committee’s charge. The ge bry ins chargTeh we ilclo bmem fuitltleye a dmdermesbseerds insh tahree fain failr mstu bdeyl ireefp oinr t,t hsec hiemdpuolerdta fnocre reolfe ansaen oins cMieanyc e2 0a0n2d. nanotechnology as the s. Paallent next revolutionary steps in science and technology. They are all enthusiastic about aiding this endeavor through ed the committee’s efforts to review the NNI. We hope that this brief document is of use to NNI managers and to ting filesetbeen acci tThhoes ecS oianmm mtuheietl t elIee.Sg litosuolpakptsi,v Cfeo hraawnidarr de xteoc duetilvivee rbirnagn cah c owmitphr eohveenrssiigvhe tr erepsoprot nats itbhieli etineds ofof rt hteh es tNudNyI ppearriotidc.ipating agencies. al typhave Committee for the Review of the National Nanotechnology Initiative ginay orim he ors m terr k, not froographic op oy er bme t p ao ps original ed, and he ain m tret oe ed frat bnnot ea es crer, c L filwev Mo Xh m g, ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri ee us ACKNOWLEDGMENT OF REVIEWERS ix s are trd. Plea ke eaert ge bry ins Acknowledgment of Reviewers Paall s. ent ed ting filesetbeen acci original typmay have in acTchoirsd arenpcoe rtw hiaths bpereonc erdeuvrieews eadp pbryo vineddi vbidyu atlhse c hNoRseCn’ sf oRr ethpeoirrt dRiveevrsieew p eCrsopmecmtiivtetese a. nTd htee chpnuircpaols ee xpoef rttihseis, he ors independent review is to provide candid and critical comments that will assist the institution in making its m terr published report as sound as possible and to ensure that the report meets institutional standards for objectivity, k, not froographic ecthvoeindifrei drneecvneit,ei awal notdof tphrreioss tpreeocpnt ostirhvte:e ninetsesg rtioty tohfe thset uddeyl ibcehraartigvee. pTrohcee srse. vWiewe wcioshm mtoe tnhtasn ka ntdh e dfroalflot wminagn uinscdriivpitd uraelms afoinr op oy er bme t Michael Crow, Columbia University, p ao original ped, and s YEMvuaerrlyky GnR oaHtgnuoe,t rsU,i ,nN Divoreretrhxswietlye U sotnef irCvnea Urlsinfiotiyvr,neiras iatyt ,S aanndta Barbara, he ain m tret Fraser Stoddart, University of California at Los Angeles. ed froeat be annot wbeefroer Aen loitthts o aursegklhee dats hetoe. Tiennhddeio vrriesdveu iaetlhwse loicsfot entdhc ilsua sbrioeovpneos rhto arw vraees c poormovvemridseeeneddn a mtbioaynn ysA, lcanonon rs Ftdoriuwdc ltteihvre,e y I cBsoMeme mTtheheno tmfsi naaasnl d Jd .Wsraufagttg soeofsn t itohRnee ssr,e etaphroecryht es crer, c Center (emeritus). Appointed by the National Research Council, he was responsible for making certain that an L filwev independent examination of this report was carried out in accordance with institutional procedures and that all Mo review comments were carefully considered. Responsibility for the final content of this report rests entirely with Xh m g, the authoring committee and the institution. ed fromattin en recomposg-specific forn. eno the original work has bation of and other typesettiding styles, for attributiauthoritative version epresentaks, hean as the digital rord breblicatio e: This new e lengths, won of this pu PDF filnal; linnt versi About this to the origiuse the pri