PRATEEK SHARMA, MD, FACP, FACG Division of Gastroenterology and Hepatology University of Kansas School of Medicine VA Medical Center Kansas City, MO Certifications  Diplomate of American Board of Gastroenterology  ECFMG certified  FLEX certified  License to practice medicine - Kansas  License to practice medicine - Missouri Academic Appointments & Clinical Experience Professor Gastroenterology & Hepatology Of Medicine: University of Kansas School of Medicine VA Medical Center, Kansas City, MO May 2007-present Program Fellowship, Gastroenterology & Hepatology Director: University of Kansas School of Medicine May 2002-present Section Gastroenterology & Hepatology Chief: VA Medical Center, Kansas City, MO October 2004-present Associate Gastroenterology & Hepatology Professor University of Kansas School of Medicine of Medicine: VA Medical Center, Kansas City, MO May 2002-April 2007 Assistant Gastroenterology & Hepatology Professor University of Kansas School of Medicine of Medicine: VA Medical Center, Kansas City, MO October 1998-April 2002 Fellowship: Gastroenterology University of Arizona, Tucson AZ July 1995-June 1998 University of Kansas, Kansas City, KS July 1998-September 1998 Residency: Internal Medicine 1 Medical College of Wisconsin, Milwaukee, WI July 1993-June 1995 Internship: Internal Medicine Christ Hospital & Medical Center, Oak Lawn, IL July 1992-June 1993 Education Graduate Education: MB, BS Bachelor of Medicine & Bachelor of Surgery MS University of Baroda, India (1986-1991) Graduated as the Valedictorian Peer Review Publications 1. Sharma P, Sampliner RE, Camargo E. Normalization of esophageal pH with high dose proton pump inhibitor therapy does not result in regression of Barrett’s esophagus. Am J Gastroenterol 1997;92:582-585. 2. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE. Dysplasia in short segment Barrett’s esophagus – a prospective three year follow-up. Am J Gastroenterol 1997;92:2012-2106. 3. Sharma P, Jaffe P, Bhattacharyya A. Metastatic cholangiocarcinoma presenting as ovarian cancer: a rare Krukenberg tumor. Am J Gastroenterol 1997;92:531-533. 4. Sharma P, Morales TG, Sampliner RE. Short segment Barrett's esophagus: the need for standardization of the definition and of endoscopic criteria. Am J Gastroenterol 1998;93:1033-6. 5. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE. Squamous islands in Barrett’s esophagus: what lies underneath? Am J Gastroenterol 1998;93:332-335. 6. Sharma P, Jaffe PE, Bhattacharyya A, Sampliner RE. Laser and multipolar electrocoagulation ablation of early Barrett’s adenocarcinoma: long term follow-up. Gastrointest Endosc 1999;49:442-6. 7. Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE. Durability of new squamous epithelium following endoscopic reversal of Barrett’s esophagus. Gastrointest Endosc 1999;50:159-64. 8. Garewal HS, Sharma P, Ramsey L, et al. Biomarker studies in reversed Barrett’s esophagus. Am J Gastroenterol 1999;94:2829-33. 9. Sharma P, Weston AP, Morales T, Topalovski M, et al. Relative risk of dysplasia for patients with intestinal metaplasia in the distal oesophagus and in the gastric cardia. Gut 2000;46:9-13. 2 10.Sharma P, Topalovski M, Mayo M, et al. H pylori eradication dramatically improves gastric carditis. Am J Gastroenterol 2000;95:3107-3111. 11.Sharma VK, Corder FA, Raufman JP, Sharma P, Fennerty MB, Howden CW. A survey of Internal Medicine residents’ use of the fecal occult blood test and their understanding of colorectal cancer screening. Am J Gastroenterol 2000;95:2068-73. 12.Weston AP, Sharma P, Topalovski M, et al. Long term follow up of Barrett’s high grade dysplasia. Am J Gastroenterol 2000;95:1888-1893. 13.Weston AP, Banerjee SK, Sharma P, et al. P53 protein overexpression positivity in low grade dysplasia in Barrett’s esophagus: immunohistochemical marker predictive of progression. Am J Gastroenterol 2001;96:1355-1362. 14.Jones TF, Sharma P, Daaboul B, Cherian R, Mayo M, Topalovski M, Weston AP. Yield of intestinal metaplasia in patients with suspected short segment-Barrett’s esophagus (SSBE) on repeat endoscopy. Dig Dis Sci 2002;47:2108-11. 15.Sharma P, Mayo M, Topalovski M, Weston AP. Methylene blue chromoendoscopy for the detection of patients with short segment Barrett’s esophagus. Gastrointest Endosc 2001;54:289-93. 16.Schmitz R, Sharma P, Qamar MJ, et al. Incidence of esophageal stricture formation, ulcer bleeding, perforation and massive hematoma formation from sclerotherapy versus banding ligation. Am J Gastroenterol 2001;96:437-441 17.da Silva VD, Prolla JC, Sharma P, et al. Karyometry in Barrett’s esophagus. Analytical & Quantitative Cytology & Histology 2001;23:40-46. 18.Sharma P. Short segment Barrett’s esophagus and specialized columnar mucosa at the gastroesophageal junction. Mayo Clin Proc 2001;76:331-334 19.Weston AP, Sharma P. Neodymium: Yttrium-aluminum garnet contact laser ablation of Barrett’s high-grade dysplasia and early carcinoma. Am J Gastroenterol 2002;97:2998-3006. 20.Sharma P, Weston AP, Topalovski M, Cherian R, Bhattaacharyya A, Sampliner RE. Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s esophagus. Gut 2003;52:24-27. 21.Sharma P, McQuaid K, Dent J. A critical review of the diagnosis and management of Barrett’s esophagus – The AGA Chicago workshop. Gastroenterology 2004;127:310-330. 3 22.Connor MJ, Weston A, Mayo MS, Sharma P. Prevalence of Barrett’s esopahgus and erosive esophagitis in patients undergoing upper endoscopy for dyspepsia in a VA population. Dig Dis Sci 2004;49:920-924. 23.Westhoff BC, Weston A, Cherian R, Sharma P. Development of Barrett’s esophagus six months after total gastrectomy. Am J Gastroenterol 2004;99:2271-7. 24.Weston AP, Sharma P, Mathur S, Banerjee S, Jafri AK, Cherian R, McGregor D, Hassanein RS, Hall M. Risk stratification of Barrett’s esophagus: updated prospective multivariate analysis. Am J Gastroenterol 2004;99:1657-1666. 25.Shaheen NJ, Inadomi JM, Overholt BF, Sharma P. What is the best management strategy for high grade dysplasia (HGD) in Barrett’s esophagus? A cost-effectiveness analysis. Gut 2004;53:1736-44. 26.Sharma P, McElhinney C, Topalovski M, Mayo M, McGregor D, Weston A. Detection of cardia intestinal metaplasia: Do the biopsy number and location matter? Am J Gastroenterol 2004;99:2424-2428. 27.Westhoff B, Weston A, Brotze S, McElhinney C, Mayo M, Sharma P. The prevalence of Barrett’s esophagus in patients with chronic gastro-esophageal reflux disease. Gastrointest Endosc 2005;61:226-31. 28.Weston AP, Sharma P, Banerjee S, Mitreva D, Mathur S. Visible endoscopic and histologic changes in the cardia, before and after complete Barrett’s esophagus ablation. Gastrointest Endosc 2005;61:515-21. 29.Wani S, Sampliner RE, Weston AP, Mathur S, Hall M, Higbee A, Sharma P. Lack of predictors of normalization of esophageal acid exposure in Barrett’s esophagus. Aliment Pharmacol Ther 2005;22:627-633. 30.Sharma P, Falk GW, Weston AP, Reker D, Johnston M, Sampliner RE. Dysplasia and cancer in a large multicenter cohort of patients with Barrett’s esophagus. Clin Gastroenterol Hepatol 2006;4:566-572. 31.Sharma P, Wani S, Weston AP, Bansal A, Hall M, Mathur S, Prasad A, Sampliner RE. A randomized controlled trial of ablation of Barrett’s esophagus with multipolar electrocoagulation vs. argon plasma coagulation in combination with acid suppression: long term results. Gut 2006;55:1233-1239. 32.Hanna S, Rastogi A, Weston AP, Totta F, Schmitz R, Mathur S, McGregor D, Cherian R, Sharma P. Detection of Barrett’s esophagus after endoscopic healing of erosive esophagitis. Am J Gastroenterol 2006;101:1416-20. 4 33.Sharma P, Bansal A, Mathur S, Wani S, Cherian R, McGregor D, Higbee A, Hall S, Weston A. The utility of a novel narrow band imaging endoscopy system in patients with Barrett’s esophagus. Gastrointest Endosc 2006;64:167-75. 34.Spechler S, Sharma P, Traxler B, Levine D, Falk G. Gastric and esophageal pH in patients with Barrett’s esophagus treated with three esomeprazole dosages: a randomized, double-blind, crossover trial. Am J Gastroenterol 2006;101:1964-71. 35.Cohen H, Moraes-Filho JP, Cafferata ML, Tomasso G, Salis G, Gonzalez O, Valenzuela J, Sharma P, Malfertheiner P, Armstrong D, Lundell L, Corti R, Sakai P, Ceconello I, Latin-American GORD Consensus Group. An evidence-based, Latin-American consensus on gastro-oesophageal reflux disease. Eur J Gastroenterol Hepatol 2006;18(4):349-68. 36.Sharma P, Dent J, Armstrong D, Bergman J, Gossner L, Hoshihara Y, Jankowski J, Junghard O, Lundell L, Tytgat G, Vieth M. The development and validation of an endoscopic grading system for Barrett’s esophagus – the Prague C and M criteria. Gastroenterology 2006;131:1392-1399. 37.Sharma P, Marcon N, Wani S, Bansal A, Mathur S, Sampliner R, Lightdale C. Non biopsy detection of intestinal metaplasia and dysplasia in Barrett’s esophagus: a prospective multicenter study. Endoscopy 2006;38(12):1206-1212. 38.Rockey DC, Barish M, Brill JV, Cash BD, Fletcher JG, Sharma P, Wani S, Wiersema MJ, Peterson LE, Conte J. Standards for gastroenterologists for performing and interpreting diagnostic computed tomographic colonography. Gastroenterology 2007;133(3):1005-1024. 39.Sharma P, Wani S, Bansal A, Hall S, Puli S, Mathur S, Rastogi A. A feasibility trial of narrow band imaging endoscopy in patients with gastroesophageal reflux disease. Gastroenterology 2007;133(2):454-64. 40.Wani S, Sharma P. Narrow band imaging in Barrett’s esophagus. Expert Rev Gastroenterol Hepatol 2007;1(1):53-60. 41.Singh S, Bansal A, Puli S, Wani S, Mathur S, Rastogi A, Sharma P. Effect of proton pump inhibitor therapy on inflammatory changes in the gastric cardia (carditis). Dig Dis Sci 2007;52(9):2178-82. 42.Rastogi A, Bansal A, Wani S, Callahan P, McGregor DH, Cherian R, Sharma P. Narrow-band imaging colonoscopy-a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosis. Gastrointest Endosc 2008;67(2):280-6. 43.Bansal A, Ulusarac O, Mathur S, Sharma P. Correlation between narrow band imaging and nonneoplastic gastric pathology: a pilot feasibility trial. Gastrointest Endosc 2008;67:210-6. 5 44.Rastogi A, Puli S, El-Serag HB, Bansal A, Wani S, Sharma P. Incidence of esophageal adenocarcinoma in patients with Barrett’s esophagus and high-grade dysplasia: a meta-analysis. Gastrointest Endosc 2008;67:394-8. 45.Sharma P, Wani S, Rastogi A, Bansal A, Higbee A, Mathur S, Esquivel R, Camargo L, Sampliner RE. The diagnostic accuracy of esophageal capsule endoscopy in patients with gastroesophageal reflux disease and Barrett’s esophagus: A blinded, prospective study. Am J Gastroenterol 2008;103:525-532 46.Wani S, Puli SR, Shaheen NJ, Westhoff B, Slehria S, Wei J, Bansal A, Rastogi A, Sayana H, Sharma P. Esophageal adenocarcinoma in Barrett’s esophagus after endoscopic ablative therapy: a meta-analysis and systematic review. Am J Gastroenterol 2009;104(2):502-513. 47.Rastogi A, Pondugula K, Bansal A, Wani S, Keighley J, Sugar J, Callahan P, Sharma P. Recognition of surface mucosal and vascular patterns of colon polyps using narrow band imaging: interobserver and intraobserver agreement and prediction of polyp histology. Gastrointest Endosc 2009;69:716-22 48.Sharma P, Shaheen NJ, Perez MC, Pilmer BL, Lee M, Atkinson SN, Peura D. Clinical trials: healing of erosive oesophagitis with dexlansoprazole MR, a proton pump inhibitor with a novel dual delayed-release formulation – results from two randomized controlled studies. Aliment Pharmacol Ther 2009;29(7):731-741 49.Shaheen NJ, Sharma P, Overholt BF, et al. Radiofrequency ablation in Barrett’s esophagus with dysplasia. N Engl J Med 2009;360(22):2277-88 50.Herrero LA, Curvers WL, Bansal A, Wani S, Kara M, Schenk E, Schoon EJ, Lynch CR, Rastogi A, Pondugula K, Weusten B, Sharma P, Bergman JJ. Zooming in on Barrett oesophagus using narrow-band imaging: an international observer agreement study. Eur J Gastroenterol Hepatol 2009;21(9):1068-75 51.Rastogi A, Keighley J, Singh V, Callahan P, Bansal A, Wani S, Sharma P. High accuracy of narrow band imaging without magnification for the real-time characterization of polyp histology and its comparison with high-definition white light colonoscopy: A prospective study. Am J Gastroenterol 2009;104(10):2422-2430 52.Bansal A, Wani S, Rastogi A, Rastogi K, Goyal A, Hall S, Singh V, Higbee A, Sharma P. Impact of measurement of esophageal acid exposure close to the gastroesophageal junction on diagnostic accuracy and event-symptom correlation: a prospective study using wireless dual pH monitoring. Am J Gastroenterol 2009;104(12):2918-2925 53.Fiocca R, Mastracci L, Riddell R, Takubo K, Vieth M, Yerian L, Sharma P, Fernstrom P, Ruth M. Development of consensus guidelines for the histologic recognition of 6 microscopic esophagitis in patients with gastroesophageal reflux disease: the Esohisto project. Human Pathology 2010;41(2):223-31 54.Wallace MB, Sharma P, Lightdale C, et al. Preliminary accuracy and interobserver agreement for the detection of intraepithelial neoplasia in Barrett’s esophagus with probe-based confocal laser endomicroscopy. Gastrointest Endosc 2010;72(1):19-24 55.Repici A, Hassan C, Sharma P, et al. Systematic review: the role of self-expanding plastic stents for benign oesophageal strictures. Aliment Pharmacol Ther 2010;31(12):1268-75 56.Lee YC, Cook MB, Bhatia S, Chow WH, El-Omar EM, Goto H, Lin JT, Li YQ, Rhee PL, Sharma P, et al. Interobserver reliability in the endoscopic diagnosis and grading of Barrett’s esophagus: an Asian multinational study. Endoscopy 2010;42:699-704 57.Wani S, Mathur SC, Curvers WL, Singh V, Herrero LA, Hall SB, Ulusarac O, Cherian R, McGregor DH, Bansal A, Rastogi A, Ahmed B, Singh M, Gaddam S, Ten Kate FJ, Bergman J, Sharma P. Greater interobserver agreement by endoscopic mucosal resection than biopsy samples in Barrett’s dysplasia. Clin Gastroenterol Heptaol 2010;8:783-88 58.Gaddam S, Wani S, Ahmed H, Maddur P, Hall SB, Gupta N, Puli SR, Higbee A, Rastogi A, Bansal A, Sharma P. The impact of pre- endoscopy proton pump inhibitor use on the classification of non- erosive reflux disease and erosive oesophagitis. Aliment Pharmacol Ther 2010;32(10):1266-74 59.Vahabzadeh A, Rastogi A, Bansal A, Sharma P. Use of a plastic endoprothesis to successfully treat esophageal perforation following radiofrequency ablation of Barrett’s esophagus. Endoscopy 2011;43(1):67-9 60.Gaddam S, Maddur P, Wani S, Gupta N, Singh M, Singh V, Moloney B, Puli SR, Rastogi A, Bansal A, Sharma P. Risk factors for nocturnal reflux in a large GERD cohort. J Clin Gastroenterol 2011, May 31 61.Bansal A, Lee IH, Hong X, Anand V, Mathur SC, Gaddam S, Rastogi A, Wani SB, Gupta N, Visvanathan M, Sharma P, Christenson LK. Feasibility of MicroRNAs as Biomarkers for Barrett’s Esophagus Progression: A Pilot Cross-Sectional, Phase 2 Biomarker Study. Am J Gastroenterol 2011;104(6):1055-63 62.Tadiparthi RA, Bansal A, Wani S, Mathur S, Hall SB, Rastogi A, Higbee A, Gaddam S, Sharma P. Dilated intercellular spaces and lymphocytes on biopsy relate to symptoms in erosive GERD but not NERD. Aliment Pharmacol Ther 2011;33(11):1202-8 63.Rastogi A, Wani S, Gupta N, Singh V, Gaddam S, Reddymasu S, Ulusarac O, Fan F, Romanas M, Dennis KL, Sharma P, Bansal A, Oropeza-Vail M, Olyaee M. A prospective, single-blind, randomized, controlled trial of EUS-guided FNA with and without a stylet. 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