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CURRICULUM VITAE Jules B. Puschett, MD, FACP, FASN, FAHA, FASH, FAAAS Research Professor of Pathobiology Texas A&M College of Veterinary Medicine & Biomedical Sciences OFFICE ADDRESS: The Spires 2001 Holcombe Blvd., #806 Houston, TX 77030 Telephone: 713-383-9313 Cell: 713/320-5432 E-Mail: [email protected] EDUCATION: 1951-1955 Lehigh University B.A. 1955-1959 University of Pennsylvania School of Medicine M.D. POST GRADUATE TRAINING: 1959-1960 Internship, Jackson Memorial Hospital University of Miami Medical School, Miami, Florida 1963-1964 Medical Residency, Jr. Assistant Resident in Medicine, University Hospital, Baltimore, Maryland 1964-1965 Assistant Resident in Medicine, University Hospital, Baltimore, Maryland 1965 Fellow, Endocrinology and Metabolism, University Hospital, Baltimore, Maryland 1966 Chief Resident in Medicine, University Hospital, Baltimore, Maryland 1966-1968 Post-Doctoral Fellow in Medicine, Institute of Arthritis and Metabolic Disease, National Institutes of Health 1966-1968 Fellow, Renal-Electrolyte Section, University of Pennsylvania School of Medicine, Department of Medicine MILITARY SERVICE: Active Duty U.S. Navy 07/60-12/61 General Medical Officer, Norfolk Navy Shipyard, Portsmouth, Virginia 12/61-07/61 Medical Officer, USS Achernar (AKA-53) 07/61-06/63 Department of Internal Medicine, U.S. Naval Hospital, Philadelphia, Pennsylvania FACULTY APPOINTMENTS: 07/67-06/69 Instructor in Medicine, University of Pennsylvania School of Medicine 07/69-06/70 Associate in Medicine, University of Pennsylvania School of Medicine 07/70-07/73 Assistant Professor of Medicine, University of Pennsylvania School of Medicine 07/67-07/73 Assistant Attending Physician, Hospital of the University of Pennsylvania 08/73-12/78 Clinical Associate Professor of Medicine, University of Pittsburgh Medical School 01/79-06/80 Professor of Medicine, University of Arkansas for Medical Sciences 07/80-06/90 Professor of Medicine, University of Pittsburgh School of Medicine 07/90-02/06 Professor of Medicine & Chair of Dept., Tulane University School of Medicine 07/02-02/06 Adjunct Professor, Department of Pharmacology, Tulane University School of Medicine 02/06-Present Emeritus Professor of Medicine, Tulane University School of Medicine 08/06-08/10 Professor of Medicine, Texas A&M College of Medicine 06/07-08/10 Member, Graduate Faculty, Texas A&M College of Medicine 01/09-08/10 Professor of Neuroscience and Experimental Therapeutics, Texas A&M College of Medicine 02/11-12/12 Adjunct Professor, Department of Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX. 01/13- Research Professor of Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX. HOSPITAL AND ADMINISTRATIVE APPOINTMENTS: 07/68-07/70 Research Associate, Veterans Administration Hospital, Philadelphia, Pennsylvania 07/68-07/73 Staff Member, Renal-Electrolyte Section, Department of Medicine, Hospital of the University of Pennsylvania 07/69-07/73 Chief, Renal-Electrolyte Section, University of Pennsylvania Medical Service, Veterans Administration Hospital, Philadelphia, Pennsylvania 07/70-07/73 Clinical Investigator, Veterans Administration Hospital, Philadelphia, Pennsylvania 08/73-12/78 Head, Renal-Electrolyte Division, Allegheny General Hospital, Pittsburgh, Pennsylvania 07/76-12/78 Director, Renal-Electrolyte Division Fellowship Training Program, University of Pittsburgh School of Medicine 01/79-06/80 Chief, Renal-Electrolyte Division, Department of Medicine, University of Arkansas for Medical Sciences 07/80-06/90 Chief, Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine 12/90-06/92 Interim Chief, Section of Nephrology, Department of Medicine, Tulane University School of Medicine 07/90-06/05 Chairman, Department of Medicine, Tulane University School of Medicine 07/96-06/05 Assistant Dean for Network Affairs, Tulane University School of Medicine 07/05-02/06 Associate Dean for North Shore Affairs, Tulane University School of Medicine 08/06-04/07 Associate Dean for Program Development, Texas A&M College of Medicine 05/07-12/07 Senior Executive Associate Dean, Texas A&M College of Medicine 08/06-Present Professor of Medicine, Texas A&M Health Science Center College of Medicine 08/06-Present Special Assistant to the Director, Central Texas Veterans Health Care System 12/06-08/10 Texas A&M Health Science Center College of Medicine 11/07-08/10 Co-Chair, Research Task Force, Scott & White Memorial Hospital 12/07-08/10 Member, Intellectual Property Committee, Scott & White Hospital 01/08-08/10 Vice Dean for Program Development, Texas A&M College of Medicine 01/09-08/10 Professor of Neuroscience and Experimental Therapeutics, Texas A&M Health Science Center College of Medicine 02/11-12/12 Adjunct Professor, Department of Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX. 01/13- Research Professor, Department of Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX. LICENSURE: Pennsylvania - 1960 California - 1963 Maryland - 1963 New Jersey - 1966 Arkansas - 1978 Louisiana - 1990 Texas - 2006 2 AWARDS, HONORS AND MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: 1951 Salutatorian, Graduating Class, Mining and Mechanical Institute, Freeland, Pennsylvania 1951 Awarded Eckley B. Coxe Memorial (full tuition) Scholarship to Lehigh University, Bethlehem, Pennsylvania 1952 Alpha Epsilon Delta 1954 Elected to Phi Beta Kappa, Lehigh University Chapter 1955 Graduated magna cum laude, Lehigh University 1955-59 Partial tuition scholarship, University of Pennsylvania School of Medicine, awarded by Joseph Collins Foundation, New York 1959 American Medical Association 1968 American Federation for Clinical Research 1969 American Society for Artificial Internal Organs 1969 American Society of Nephrology 1992 Chairman, Audit Committee 1969 American College of Physicians, Member 1992 American College of Physicians, Fellow 1970 National Kidney Foundation 1989 Public Policy Committee 1990 Volunteer Service Award 1970 International Society of Nephrology 1973 American Heart Association, Council on the Kidney in Cardiovascular Disease 1991-93 Chairman, Executive Committee 1991-92 Chairman, Subcommittee on Scientific Conferences 1992-94 Long-Range Planning Committee 2002 Science Advisory and Coordinating Committee 1995- American Heart Association, Council for High Blood Pressure Research 1973 American Physiological Society 1973 American Association for the Advancement of Science 1973 Federation of American Societies for Experimental Biology 1974 American Geriatrics Society 1976 Midwestern Salt and Water Club 1977 Central Society for Clinical Research 1978 European Dialysis and Transplant Association 1978 Society for Experimental Biology and Medicine 1978 American Society for Clinical Pharmacology and Therapeutics 1981 National Kidney Foundation of Western Pennsylvania, Medical Advisory Committee 1981-83 National Kidney Foundation of Western Pennsylvania, Chairman 1991 Recipient, Gift of Life Award, Natl Kidney Foundation of Western Pennsylvania 1982 American College of Clinical Pharmacology 1983 The Endocrine Society 1984 American Society of Renal Biochemistry and Metabolism 1984, '86 International Conference on Diuretics, Chairman 1989, '92 International Conference on Diuretics, Chairman 3 1985 American Society of Hypertension 1986 Outstanding Teacher Award, University of Pittsburgh School of Medicine 1990 Association of Professors of Medicine 1990 International Society of Nutrition and Metabolism in Renal Disease 1990 National Kidney Foundation of Louisiana, Member-at-Large 1991 National Kidney Foundation of Louisiana, Member, Board of Trustees 1991 Outstanding Teacher Award, Owl Club, Tulane University School of Medicine 1991 American Society of Bone and Mineral Research 1991 Southern Medical Association 1991 Southern Society for Clinical Investigation 1992-94 Councilor 1994 Secretary-Treasurer-Elect 1995-99 Secretary-Treasurer 1998-99 President-Elect 1999-2000 President 2007-2013 Member, Executive Advisory Committee 1991 Louisiana State Medical Society 1991 Orleans Parish Medical Society 1993 Member, Membership Committee 1993 Long-range Planning Committee 1992 Louisiana Society of Internal Medicine 1992, '96 Faculty Teaching Honor Roll, Owl Club, Tulane University School of Medicine 1994 Outstanding Teaching Award, Owl Club, Tulane University School of Medicine 1994 Southeastern Clinical Club 1996-97 Department of Medicine awarded "Outstanding Department," Owl Club, Tulane University School of Medicine 1996-97 Outstanding Teacher Award, presented by Tulane Department of Medicine House Staff 1998 Alpha Omega Alpha, National Honor Medical Society; Tulane Stars and Bars Chapter 1998 Gloria P. Walsh Award for Teaching Excellence, awarded by graduating class, Tulane University School of Medicine 1998 Charter Awardee: A.N. Richards Distinguished Achievement Award in Nephrology, University of Pennsylvania School of Medicine, Renal-Electrolyte and Hypertension Division, Department of Medicine 1998-2000 Listed in Who’s Who in America 1998-present American Heart Association, Council on the Kidney in Cardiovascular Disease, Executive Committee 1999-2001 American Heart Association, Council on the Kidney in Cardiovascular Disease, Executive Committee Vice-Chairman 2001-2003 American Heart Association, Council on the Kidney in Cardiovascular Disease, Executive Committee Chairman 1999 Invested as the first incumbent of the Harry B. Greenberg, M.D. Chair in Internal Medicine 1999 Designated Specialist in Clinical Hypertension by the ASH Specialist Program, Inc. of the American Society of Hypertension 1999-2000 Department of Medicine awarded "Outstanding Department" in the School of Medicine by the Owl Club, Tulane University School of Medicine 1999-2001 Listed in Who’s Who in Medicine and Healthcare 2000 Honored by the Musser-Burch Society and the Faculty, Department of Medicine, Tulane University School of Medicine, on the 10th anniversary of Dr. Puschett’s Chairmanship of the Department of Medicine. An award entitled the "Musser-Burch-Puschett" award was 4 established for presentation each year to the outstanding house officer in the Department’s training program. Events included a scientific session and a dinner on September 16, 2000. 2000 Listed in Best Doctors in America. 2001 Listed in Who’s Who in the World. 2001 Special Recognition Award for Excellence in Academia/Research, Orleans Parish Medical Society. 2001 American Medical Association (Lifetime Member) 2001 Elected a Fellow of the American Association for the Advancement of Science 2001 Listed in "Top Doctors," New Orleans Magazine 2002 Listed in Who’s Who in the South and Southwest 2002 Listed in Who’s Who in the World 2002 American Heart Association Scientific Councils 2002 American College of Cardiology/American Heart Association Committee to Develop Guidelines for the Management of Patients with Peripheral Arterial Disease (Excluding Carotids) 2002 Elected a Fellow in the Council for High Blood Pressure Research of the American Heart Association 2002 Listed in Best Doctors 2002 Listed in 2000 Eminent Scientists of Today, 1st Edition, International Biographical Centre, Cambridge, England 2002 Scientific Councils Distinguished Achievement Award, American Heart Association 2002 Board Member, American Heart Association of Greater New Orleans 2002 Elected to Fellowship in the Council on High Blood Pressure Research of the American Heart Association. 2003 Listed in Who’s Who in America 2003 Awarded Founder’s Medal of Southern Society for Clinical Investigation 2002-2003 Listed in Who’s Who in Medicine and Healthcare 2003 Jules B. Puschett, M.D. Research Endowment Fund established at the Tulane University School of Medicine 2003-2006 Member of Selection Committee for Distinguished Scientist Award of the American Heart Association 2003 Elected a Fellow of the American Heart Association, Council on the Kidney in Cardiovascular Disease 2003 Member, VA Research and Education Committee 2003 BIRCWH (Building Interdisciplinary Research Careers in Women’s Health) Advisory Board 2004 Gloria P. Walsh Award for Teaching Excellence, awarded by graduating class, Tulane University School of Medicine 2004 Member, Association of Professors in Medicine Finance Committee 2005 C. Thorpe Ray Outstanding Faculty Teacher Award, awarded by graduating residents, 2004- 2005 academic year, Tulane University School of Medicine. 2006-2007 Listed in Who’s Who in Science and Engineering 2007 Listed in Who’s Who in America 2007 Listed in Who’s Who in the World 2007 Elected a Fellow of the American Society of Nephrology 2007 Listed in Guide to America’s Top Physicians 2008 Listed in Who’s Who in America 2008 Listed in Who’s Who in the World 2008 Listed in America’s Top Doctors 5 EDITORIAL BOARDS: The American Journal of the Medical Sciences American Journal of Nephrology Section Editor "Physiology for the Nephrologist" Cardiovascular Risk Factors International Journal of Artificial Organs Mineral and Electrolyte Metabolism Southern Medical Journal UNIVERSITY AND HOSPITAL ACTIVITIES: Member, Patient Care Committee, Presbyterian-University Hospital, 1980-1981 Member, Transplantation Committee, Presbyterian-University Hospital, 1981-1990 Chairman, Animal Care Committee, University of Pittsburgh, 1981-1984 Chairman, Finance Committee, Department of Medicine Practice Plan, 1981-1990 Member, Faculty Committee on Non-Tenured Appointments, University of Pittsburgh, 1984-1986 Member, Executive Committee, University of Pittsburgh School of Medicine, 1985-1988 Member, Internship Selection Committee, Department of Medicine, University of Pittsburgh School of Medicine, 1985-1989 Member, Research and Development Committee, Oakland Veterans Administration Hospital, Pittsburgh, Pennsylvania 1985-1987; Chairman: 1986-1987 Member, Budget Committee, Presbyterian-University Hospital, 1985-1987 Chairman, Grievance Committee, Department of Medicine Residency Program, University of Pittsburgh, 1987-1990 Member, Physician Advisory Committee, Presbyterian-University Hospital, 1988-1990 Chairman, Continuing Medical Education Faculty Committee, University of Pittsburgh School of Medicine, 1990 Member, Personnel and Honors Committee, Tulane University School of Medicine, 1990- 1993 Member, Budget and Finance Subcommittee, Tulane University Medical Center, 1990-2005 Member, Executive Committee of the Faculty Practice Plan, Tulane University Medical Center, 1990-2005 Member, Revision Subcommittee of the Faculty Practice Plan, Tulane University Medical Center, 1991-1992 Member, Executive Committee of the Medical Staff, Tulane University Medical Center, 1990-2005 Member, Executive Faculty Committee, Tulane University School of Medicine, 1990-2005 Member, Charity Hospital Executive Committee, New Orleans, 1990-2005 Member, Clinical Sciences Council, Tulane University School of Medicine, 1990-2005 Member, Clinical Sciences Council Budget Subcommittee, Tulane University School of Medicine, 1992-2000 Member, Dean's Committee, VA of Alexandria, Louisiana, 1990-2000 Member, Dean's Committee, VA of New Orleans, Louisiana, 1990-2005 Member, Dean's Task Force on Space, 1992 6 Chairman, Search Committee for the Tulane Cancer Center Director, Tulane University Medical Center, 1992 Member, Cancer Center Task Force, Tulane University Medical Center, 1992-1993 Chairman, Search Committee for the Dean, Tulane University School of Medicine, 1993 Member, Task Force on Health Care Reform, Tulane University Medical Center, 1993-1994 Member, Heart Transplant Committee, Tulane University Medical midpoint, 1993-1996 Participation in APM/Wyeth-Ayerst Executive Management Program for Chairs of Medicine at Wharton School of the University of Pennsylvania, Philadelphia, Pennsylvania, July 24-29, 1994. Member, Chancellor's Task Force on Establishment of an Institute for Gene Therapy, 1994 Member, Network Task Force, 1994 -1995 Member, Nominating Committee, Tulane University Medical Center PHO Board of Directors, 1995-1996 Member, Tulane 2000 Steering Committee, 1995-1996 Member, Clinical Sizing Committee, 1996 Member, Chancellor’s Task Force for Establishment of a Center of Excellence in Cardiovascular Diseases, 1996-1998 Member, Chancellor’s Task Force for Establishment of an Institute of Infectious Diseases, 1996-1997 Chairman, Network Affairs Committee, 1997-2003 Member, Faculty Incentive Committee, 1997-1998 Member, Tulane University Inauguration Committee, 1998 Member, Tulane University Strategic Planning Framework Committee, 1998-1999 Chairman, Search Committee for the Chair of the Department of Family and Community Medicine, 1997-1998 Member, Search Committee for the Director of the Gene Therapy Center of Excellence, Tulane University Medical Center, 1998-1999 Chairman, Surgery Chair Search Committee, 1999-2000 Member, Dean’s Committee on Clinical Enterprise Strategic Planning, 2002-2003 Member, Dean’s Committee on Space for the School of Medicine, 2001-2002 Search Committee for Aron Professorship in Gene Therapy, 2002 Tulane University Medical Group, Restructuring Committee, 2004-2005 Tulane University School of Medicine Space Committee, 2004-2005 Member, Internal Medicine Research Committee, Texas A&M College of Medicine/Scott & White- 2006 Member, Executive Committee, Texas A&M College of Medicine/Scott & White- 2006- Member, Academic Council Committee, Texas A&M College of Medicine/Scott & White- 2006- Member, Graduate Medical Education Committee, Texas A&M College of Medicine/Scott & White- 2006- Member, Basic Science Department Head Committee, Texas A&M College of Medicine/Scott & White- 2006-2010 Member, Research & Education Council, Texas A&M College of Medicine/Scott & White-2006-2010 Chair, Subcommittee on Program Development, Research & Education Council, Texas A&M College of Medicine/Scott & White-2006-2010 Member, Search Committee, Chief of Endocrinology, Department of Medicine, Texas A&M College of Medicine/Scott and White 2006-2010 Member, Focus Group, Clinical and Translational Research Strategies Planning Grant, 2006-2010 Member, Search Committee for ACOS for Mental Health, Central Texas VA Healthcare System, 2006-2007 Member, Academic Council, Texas A & M College of Medicine, 2006-2010 Member, Executive Committee, Texas A & M College of Medicine, 2006-2010 Member, Search Committee for Associate Chief of Staff-Research, Central Texas Veterans Health Care, 2007 Chair, Search Committee for Chief of Medicine, Central Texas Veterans Health Care, 2007 Member, Department of Medicine Promotions and Tenure Committee, Texas A&M College of Medicine/Scott & White, 2007-2010 7 Co-Chair, Research Task Force, Scott & White Hospital, 2007-2008 Member, Advisory Committee to the Institute for Regenerative Medicine, Texas A&M College of Medicine/Scott & White, 2008-2010 President, VoluMedex, LLC, 2002-2006 President, Bufogen, LLC, 2006-present Chairman, Scientific Advisory Board, Personal Therapeutics, 2010-2011 COMMUNITY ACTIVITIES: Chairman, First Annual Kidney Ball, National Kidney Foundation of Western Pennsylvania, September 10, 1988 Chairman, Second Annual Kidney Ball, National Kidney Foundation of Western Pennsylvania, September 9, 1989 PATENTS: U.S. Patent Number 5077078. Surface Modification of Plastic Optical Fibers; issued 12/31/91. U.S. Patent Number 5236667. Surface Modification of Plastic Optical Fibers; U.S. Divisional. Issued 8/17/93. Diagnosis of Essential Hypertension: U.S. Patent # 6,251,611, issued 6/26/01: "Method of Determining Volume Dependent Hypertension through Protein Reduction in Phosphorylation or Concentration and Related Apparatus." Methods of Diagnosing Preeclampsia: U.S. Patent Application "Method of Employing Reduction in Phosphorylation or Concentration of a Specific Protein in Determining the Presence of Preeclampsia and Related Apparatus." Method of Employing Marinobufagenin in Diagnosis of Preeclampsia: PCT Application "Method of Employing Elevation of Marinobufagenin in Determining the Presence of Preeclampsia and Related Apparatus." Method of Using Metolazone in Treatment of Preeclampsia: U.S. Patent Application # "Method of Treating Preeclampsia Employing Metolazone." Method of Treating Human Preeclampsia Employing Resibufogenin. U.S. Patent Application. Method of Treating Human Volume Expansion Mediated Hypertension Employing Resibufogenin. U.S. Patent Application. PUBLICATIONS: Articles 1. The acute effects of furosemide on acid and electrolyte excretion in man. J.B. Puschett, M. Goldberg. J Lab Clin Med 71:666-677, 1968. 2. Proximal tubular malfunction as a mechanism for diuresis following renal homotransplantation. L.W. Henderson, K.D. Nolph, J.B. Puschett, M. Goldberg. New Engl J Med 278:467-473, 1968. 3. Endocrinopathy associated with pineal tumor. J.B. Puschett, M. Goldberg. Ann Intern Med 69:203-219, 1968. 4. The relationship between the renal handling of phosphate and bicarbonate in man. J.B. Puschett, M. Goldberg. J Lab Clin Med 73:956-969, 1969. 5. Mechanism of exaggerated natriuresis in hypertensive man: Impaired sodium transport in the loop of Henle. V.M. Buckalew, Jr., J.B. Puschett, J.E. Kintzell and M. Goldberg. J Clin Invest 48:1007-1016, 1969. 8 6. Effects of increased sodium delivery on distal sodium reabsorption, with and without volume expansion. V.M. Buckalew, Jr., J.B. Puschett, B.R. Walker and M. Goldberg. J Clin Invest 49:2336-2344, 1970. 7. Effects of filtration rate and plasma sodium concentration on proximal sodium transport. J.B. Puschett, S. Goldstein, S. Godshall, B.B. Staum and M. Goldberg. Am J Physiol 221:788-794, 1971. 8. Mode of action of parathyroid hormone and cyclic adenosine 3', 5’-monophosphate on renal tubular phosphate reabsorption in the dog. Z.S. Agus, J.B. Puschett, D. Senesky, and M. Goldberg. J Clin Invest 50:617-626, 1971. 9. Effects of saline loading and aortic obstruction on proximal phosphate transport. J.B. Puschett, Z.S. Agus, D.J. Senesky and M. Goldberg. Am J Physiol 223:851-857, 1972. 10. Evidence for a direct action of cholecalciferol and 25-hydroxy-cholecalciferol on the renal transport of phosphate sodium and calcium. J.B. Puschett, J. Moranz and W. Kurnick. J Clin Invest 51:373-385, 1972. 11. Lithium-induced nephrogenic diabetes insipidus: in vivo and in vitro studies. I. Singer, D. Rotenberg, J.B. Puschett, E.A. Franko. J Clin Invest 51:1081-1091, 1972. 12. Effects of metolazone in man: Comparison with chlorothiazide. S.R. Steinmuller and J. B. Puschett. Kidney Int 1:169-181, 1972. 13. The acute renal tubular effects of 1, 25-dihydroxy-cholecalciferol. J.B. Puschett, P.C. Fernandez, I.T. Boyle, R.W. Gray, J.L. Omdahl and H.F. DeLuca. Proc Soc Exp Biol Med 141:379-384, 1972. 14. Mode of phosphaturic action of parathyroid hormone: Micropuncture studies. M. Goldberg, Z. Agus, J.B. Puschett, D. Senesky. In: Calcium, Parathyroid Hormone and Calcitonins, (Eds. R.V. Talmage and P.L. Munson), Proc. Fourth Parathyroid Conf., Excerpta Medica, Amsterdam, 1972, pp. 273-283. 15. Metolazone - mechanism and sites of action. J.B. Puschett, S. Steinmuller, A. Rastegar and P.C. Fernandez. In: Modern Diuretic Therapy in the Treatment of Cardiovascular and Renal Disease. Excerpta Medica Foundation, Amsterdam, 1973, pp. 168-175. 16. Sites of action of benzothiadiazines, furosemide and ethacrynic acid. M. Goldberg, J.B. Puschett, L.H. Beck and J.J. Schubert. In: Modern Diuretic Therapy in the Treatment of Cardiovascular and Renal Disease. Excerpta Medica Foundation, Amsterdam, 1973, pp. 135-147. 17. Proximal tubular actions of metolazone and chlorothiazide. P.C. Fernandez, J.B. Puschett. Am J Physiol 225: 954-961, 1973. 18. Study of the renal tubular interactions of thyrocalcitonin, cyclic adenosine 3', 5'-monophosphate, 25- hydroxycholecalciferol and calcium ion. J.B. Puschett, W. Beck, A. Jelonek and P.C. Fernandez. J Clin Invest 53:756-767, 1973. 19. Effects of 25-hydroxyvitamin D on urinary electrolyte excretion in hypophosphatemic rickets. J.B. Puschett, 3 M. Genel, A. Rastegar, C. Anast and H.F. DeLuca. Lancet 2:920-922, 1974. 20. Comparative study of the effects of metolazone and other diuretic agents on potassium excretion. A. Rastegar, J.B. Puschett. Clin Pharmacol Ther 15:397-405, 1974. 9 21. Re-evaluation of microelectrode methodology for the in vitro determination of pH and bicarbonate concentration. J.B. Puschett, P. Zurbach. Kidney Int 6:81-91, 1974. 22. Prolonged therapy of vitamin D-resistant rickets with 25-hydroxy-cholecalciferol and oral phosphate. J.B. Puschett, M. Genel, A. Rastegar, A. Anast, H.F. DeLuca and A. Friedman. Clin Pharmacol Ther 17:202-211, 1975. 23. Parathyroid hormone and 25-hydroxyvitamin D : Synergistic and antagonistic effects on renal phosphate 3 transport. J.B. Puschett, W.S. Beck, Jr. Science 190:473-475, 1975. 24. Acute effects of parathyroid hormone on proximal bicarbonate transport in the dog. J.B. Puschett, P. Zurbach. Kidney Int 9:501-510, 1976. 25. Site and mechanism of the phosphaturia due to volume expansion. J.B. Puschett, D. Sylk. In: Phosphate Metabolism, Kidney and Bone, (Eds. L. Avioli, P. Bordier, H. Fleisch, S. Massry and E. Slatopolsky), Armour-Montague, Paris, June 1975, pp. 103-109. 26. Renal transport and blood flow effects of certain antihypertensive/diuretic agents. J.B. Puschett, M Kuhrman. In: Systemic Effects of Antihypertensive Agents, Stratton, New York, 1976, pp. 157-169. 27. Importance of 25-hydroxylation to the renal tubular actions of vitamin D metabolites. J.B. Puschett, J. Szramowski. In: Advances in Experimental Biology and Medicine. Homeostasis of phosphate and other minerals, (Eds. S.G. Massry, E. Ritz and A. Rapado). 103:105-110, 1976. 28. Renal tubular effects of vitamin D and its metabolites. J.B. Puschett. In: Phosphate Metabolism, Kidney and Bone, (Eds. L. Avioli, P. Bordier, H. Fleisch, S. Massry and E. Slatopolsky), Armour-Montague, Paris, 1976, pp. 29-40. 29. Effects of volume expansion and parathyroid hormone on total renal blood flow and its intracortical distribution. H.A. Feldman, M. Kuhrman, J.B. Puschett. J Lab Clin Med 89:959-970, 1977. 30. Study of the sites and mechanisms of action of bumetanide in man. S. Jayakumar, J.B. Puschett. J Pharm Exp Ther 201:251-258, 1977. 31. Renal tubular sodium and phosphate transport inhibitory mechanisms of proximally active agents. J.B. Puschett, J. Szramowski and N.I. Nseir. J Pharmacol Exp Ther 203: 264-271, 1977. 32. Relationship between serum phosphate concentration and proximal tubular bicarbonate transport. J.B. Puschett, P.C. Fernandez, D. Sylk and W.S. Beck, Jr. Nephron 19: 44-52, 1977. 33. Physiological basis for the use of new and older diuretics in congestive heart failure. J.B. Puschett Cardiovasc Med 2:119-138, 1977. 34. Renal micropuncture studies of parathyroid hormone action on the kidney. J.B. Puschett, D. Sylk. In: Endocrinology of Calcium Metabolism, (editors D.H. Copp and R.V. Talmage), Excerpta Medica, Amsterdam, 1977, pp. 226-229. 35. Idiopathic edema: Review of etiologic concepts and management. H.A. Feldman, S. Jayakumar, J.B. Puschett. Cardiovasc Med 3:475-488, 1978. 36. Post-obstructive diuresis following ovarian cystectomy in a non-azotemic female. R.M. Gromis, H.A. 10

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S. Goldstein, S. Godshall, B.B. Staum and M. Goldberg. Am J Physiol .. In: Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals,. (Eds. M. DeBroe, W. Bennett, . AB Alper, Y Yi, L Webber, J Martin, G Saade,. M Belfort, G
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