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Nates, MD, MBA, CMQ, MCCM Chief Academic Officer Professor, Deputy Chair The University of Texas MD Anderson Cancer Center; Director Surgical and Medical Intensive Care Units Division Head Critical Care Department Anesthesiology, Critical Care & Pain Medicine Division of Anesthesiology, Critical Care & Pain Medicine The University of Texas MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center Houston, TX, USA; Houston, TX, USA Bud Johnson Clinical Distinguished Chair Donal J. Buggy, DSc, MD, MSc, DME, Vijaya N. R. Gottumukkala, MBBS, FRCPI, FFSEM, FRCA, FCAI MD(Anes), FRCA Professor Professor Anaesthesiology & Perioperative Medicine Anesthesiology & Perioperative Medicine Mater Misericordiae University Hospital, School of Medicine, The University of Texas MD Anderson Cancer Center University College Dublin; Houston, TX, USA Consultant Anaesthesiology Bernhard J. Riedel, MD, MBA, PhD Mater Misericordiae University Hospital Dublin, Dublin, Ireland Professor Anesthesiology, Perioperative and Pain Medicine Peter MacCallum Cancer Centre Melbourne, Victoria, Australia Elsevier 1600 John F. Kennedy Blvd. Ste 1800 Philadelphia, PA 19103-2899 PERIOPERATIVE CARE OF THE CANCER PATIENT ISBN: 978-0-323-69584-8 Copyright © 2023 by Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions. This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein). Notice Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made. To the fullest extent of the law, no responsibility is assumed by Elsevier, authors, editors, or contributors for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Library of Congress Control Number: 2021947605 Publisher: Sarah Barth Senior Content Development Manager: Somodatta Roy Choudhury Senior Content Development Specialist: Malvika Shah Publishing Services Manager: Shereen Jameel Senior Project Manager: Manikandan Chandrasekaran Design Direction: Julia Dummitt Printed in India Last digit is the print number: 9 8 7 6 5 4 3 2 1 We dedicate this issue to all of our cancer patients and their loved ones. We find inspiration for our ongoing clinical, research, and educational efforts from their fighting spirit, courage, strength, and hope for a cure. Contributors Salahadin Abdi, MD, PhD Rosalind S. Bello, MA, CPHQ Professor and Chair Director Pain Medicine Cancer Control Health Policy The University of Texas MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center Houston, TX, USA Houston, TX, USA Anoushka M. Afonso, MD Shamgar Ben-Eliyahu, PhD Associate Attending Sagol School of Neuroscience and School of Department of Anesthesiology & Critical Care Psychological Sciences Memorial Sloan Kettering Cancer Center Tel-Aviv University New York, NY, USA Tel-Aviv, Israel Thomas A. Aloia, MD Celena Scheede Bergdahl, MSc, PhD Professor of Surgery Professor Surgical Oncology Department of Kinesiology and Physical Education The University of Texas MD Anderson Cancer Center McGill University Houston, TX, USA Montreal, Quebec, Canada Gabriele Baldini, MD, MSc Sushma Bhatnagar, MD Assistant Professor, Anesthesiologist Professor and Head Anesthesia Department of Onco-Anesthesia and Palliative Medicine McGill University Health Centre, Montreal General Institute Rotary Cancer Hospital and National Hospital Cancer Institute Montreal, Quebec, Canada All India Institute of Medical Sciences New Delhi, India Jose Banchs, MD Associate Professor Joshua Botdorf, DO, FACP, CMQ Cardiology Assistant Professor The University of Texas MD Anderson Cancer Center Critical Care and Respiratory Medicine Houston, TX, USA The University of Texas MD Anderson Cancer Center Houston, TX, USA Daniel T. Baptista-Hon, BSc, MSc, PhD Assistant Professor Christelle Botha, FANZCA Faculty of Medicine Consultant Anatesthetist Macau University of Science and Technology Department of Cancer Anaesthesia Macau, SAR, China Perioperative and Pain Medicine, Peter MacCallum Honorary Lecturer, School of Medicine Cancer Centre University of Dundee Melbourne, Victoria, Australia Dundee, United Kingdom David L. Brown, MD Karen Basen-Engquist, PhD Chief Executive Officer Professor Curadux Inc. Department of Behavioral Science Austin, TX, USA Division of Cancer Prevention and Population Sciences The University of Texas MD Anderson Cancer Center Houston, TX, USA iv Contributors v Donal J. Buggy, DSc, MD, MSc, DME, FRCPI, FFSEM, German Corrales, MD FRCA, FCAI Department of Anesthesiology and Perioperative Medicine Professor The University of Texas MD Anderson Cancer Center Anaesthesiology & Perioperative Medicine Houston, TX, USA Mater Misericordiae University Hospital, School of Medicine, University College Dublin Jose Cortes, MD Consultant, Assistant Professor Anaesthesiology Pediatrics Mater Misericordiae University Hospital Dublin The University of Texas MD Anderson Cancer Center Dublin, Ireland Houston, TX, USA Kate L. Burbury, MBBS(Hons), FRACP, FRCPA, DPhil Kimberly D. Craven, MD Deputy Chief Medical Officer Clinical Assistant Professor Executive Department of Anesthesiology Peter MacCallum Cancer Centre; Perioperative Care & Pain Management Consultant Haematologist NYU Langone – Brooklyn DHMO Brooklyn, NY, USA Peter MacCallum Cancer Centre Melbourne, Victoria, Australia John Wilson Crommett, MD Associate Professor Joseph Butler, PhD, FACS, FRCS Critical Care Medicine Consultant Spine Surgeon The University of Texas MD Anderson Cancer Center National Spinal Injuries Unit Houston, TX, USA Mater Misericordiae University Hospital Dublin, Ireland Kristin P. Crosby, MD Fellow Ronan Cahill, MB, BAO, BCh, FRCS, MD Pediatric Critical Care Medicine UCD Centre for Precision Surgery New York Presbyterian Hospital – Weill Cornell Medicine Surgery New York, NY, USA University College Dublin Surgery Luis Felipe Cuellar Guzman, MD Mater Misericordiae University Hospital Anesthesiologist in Oncological Patient and Pain Medicine Dublin, Ireland Specialist Anesthesiology Department Head National Institute of Franco Carli, MD, MPhil Cancer Mexico; Professor Onco Anesthesia Anesthesia National Institute of Cancer Mexico McGill University Mexico City, Mexico; Montreal, Quebec, Canada Professor Course Cancer Anesthesia Fellowship Program National Institute of Cancer Mexico Meghan Carton, BM, BS Anesthesiology Department Doctor National Institute of Cancer Anaesthetics Mexico Mater Misericordiae University Hospital Dublin, Ireland Anahita Dabo-Trubelja, MD, FASA Associate Attending Juan P. Cata, MD Anesthesiology and Critical Care Professor Memorial Sloan Kettering Cancer Center Department of Anesthesiology and Perioperative Medicine New York, NY, USA The University of Texas MD Anderson Cancer Center Houston, TX, USA Anh Quynh Dang, MD Associate Professor Cara Connolly, MB, BCh, BAO, LRCP & SI (Hons), MSc, Anesthesiology and Preoperative Medicine FCAI The University of Texas MD Anderson Cancer Center Consultant Anaesthetist Houston, TX, USA Department of Anaesthesia Mater Misericordiae University Hospital Dublin, Ireland vi Contributors Alessandro R. De Camilli, MD Mats Enlund, MD, PhD Assistant Attending, Anesthesiology and Critical Care Associate Professor Medicine Centre for Clinical Research-Västerås Anesthesiology and Critical Care Uppsala University Memorial Sloan Kettering Cancer Center Västerås, Sweden; New York NY, USA Senior Consultant Department of Anaesthesia & Intensive Care Madhavi D. Desai, DA, DNB Central Hospital Assistant Professor and Consultant Västerås, Sweden Department of Anaesthesia , Critical Care and Pain Tata Memorial Hospital and Homi Bhabha National Linette Ewing, DO, MPH Institute Assistant Professor Mumbai, Maharashtra, India Pediatric Critical Care The University of Texas MD Anderson Cancer Center Jugdeep Dhesi, BSc, PhD, FRCP Houston, TX, USA Consultant Geriatrician Ageing and Health Dylan Finnerty, FCAI, FJFICMI, EDICM Guy’s and St Thomas’ NHS Trust Research Fellow London, United Kingdom; Anaesthesiology & Perioperative Medicine Hon. Reader Mater Misericordiae University Hospital University Kings College London College Dublin London, United Kingdom; Dublin, Ireland Hon. Associate Professor University College London Joël Fokom Domgue, MD, MPH London, United Kingdom Research Scientist Epidemiology Jeson R. Doctor, MD, DNB, MNAMS, MBBS The University of Texas MD Anderson Cancer Center Professor and Consultant Anaesthesiologist Houston, TX, USA Department of Anaesthesiology Critical Care and Pain Tata Memorial Hospital John Frenzel, MD, MS Homi Bhabha National Institute Director, Learning Health System Mumbai, Maharashtra, India Institute for Cancer Care Innovation The University of Texas MD Anderson Cancer Center Jennifer S. Downs, MMed, FCS(SA) Houston, TX, USA Surgical Oncology Fellow Cancer Surgery Colleen M. Gallagher, PhD, FACHE, HEC-C Peter MacCallum Cancer Centre Executive Director Melbourne, Victoria, Australia Section of Integrated Ethics The University of Texas MD Anderson Cancer Center Julia A. Dubowitz, MBBS Professor Specialist Anaesthetist Department of Critical Care Medicine Department of Anaesthetics, Perioperative and The University of Texas MD Anderson Cancer Center Pain Medicine Houston, TX, USA; Peter MacCallum Cancer Centre Research Scholar Clinical Fellow UNESCO Chair in Bioethics and Human Rights Department of Critical Care Rome, Italy University of Melbourne Parkville, Melbourne, Australia Dorian Yarih García-Ortega, MD, MSc, FACS Master in Musculoskeletal Tumors German Echeverry, MD Surgeon Oncologist Attending Physician Skin, Soft Tissue and Bone Tumors Department Department of Anesthesiology and Critical Care Medicine National Cancer Institute Memorial Sloan Kettering Cancer Center Mexico City, Mexico New York, NY; Attending Physician Department of Anesthesia Mount Sinai Medical Center Miami Beach, FL, USA Contributors vii Michelle Gerstman, MBBS, FANZCA, MD Ernest Hawk, MD, MPH Consultant Anaesthetist Vice President and Division Head Anaesthetics, Perioperative Medicine and Pain Medicine Division of Cancer Prevention and Population Sciences Peter MacCallum Cancer Centre T. Boone Pickens Distinguished Chair for Early Prevention Melbourne, Victoria, Australia of Cancer The University of Texas MD Anderson Cancer Center Arunangshu Ghoshal, MD, MRes Houston, TX, USA Assistant Professor Palliative Medicine Alexander G. Heriot, MB BChir, MA, MD, MBA, FRACS, Tata Memorial Hospital FRCS(Gen.), FRCSEd, FACS, FASCRS, GAICD Homi Bhaba National Institute Director of Surgery Mumbai, Maharashtra, India Division of Cancer Surgery Peter MacCallum Cancer Centre Vijaya N.R. Gottumukkala, MBBS, MD(Anes), FRCA Melbourne, Victoria, Australia Professor Anesthesiology & Perioperative Medicine Joseph M. Herman, MD The University of Texas MD Anderson Cancer Center Director of Clinical Research Houston, TX, USA Northwell Health New Hyde Park, NY, USA Michael P.W. Grocott, MB, BS, MD, FRCA, FRCP, FFICM Professor Jonathan G. Hiller, MBBS, GCEpi, MAICD, FANZCA, PhD Respiratory and Critical Care Research Theme Division of Surgical Oncology Southampton NIHR Biomedical Research Centre Anaesthesia University Hospital Southampton NHS Foundation Trust/ Peter MacCallum Cancer Centre University of Southampton Parkville, Victoria, Australia; Southampton, United Kingdom; Central Clinical School Anaesthesia, Perioperative and Critical Care Medicine Medicine, Nursing and Health Sciences Research Unit Monash University University Hospital Southampton NHS Foundation Trust Prahran, Victoria, Australia Southampton, United Kingdom Ruth E. Hubbard, BSc, MBBS, MRCP, MSc, MD, FRACP Carlos E. Guerra-Londono, MD Professor Department of Anesthesiology, Pain Management, and Centre for Health Services Research Perioperative Medicine University of Queensland Henry Ford Health System Brisbane, Queensland, Australia Detroit, MI, USA Hilmy Ismail, MD, FRCA, FANZCA Sushan Gupta, MD Consultant Anaesthetist Department of Internal Medicine Anaesthesia and Preoperative Medicine Carle Foundation Hospital PeterMacCallum Cancer Center Champaign, IL, USA Melbourne, Victoria, Australia; Senior Lecturer David E. Gyorki, MBBS, MD, FRACS Anaesthesia Surgical Oncologist University of Melbourne Division of Cancer Surgery Melbourne, Victoria, Australia Peter MacCallum Cancer Centre Melbourne, Victoria, Australia Nelda Itzep, MD Assistant Professor Tim G. Hales, BSc, PhD Pediatrics Professor of Anaesthesia The University of Texas MD Anderson Cancer Center Institute of Academic Anaesthesia Houston, TX, USA University of Dundee, Dundee, Scotland United Kingdom viii Contributors Emily Jasper, MBBS (Hons) Faraz Khan, MB, BCh, BAO, MRCS, MD, MSc Research Registrar Specialist Surgical Lecturer Ageing and Health Colorectal Surgery Guy’s and St Thomas’ NHS Foundation Trust Mater Misericordiae University Hospital London, United Kingdom; Dublin, Ireland Senior Registrar/Advanced Trainee Department of Rehabilitation and Aged Care James S. Killinger, MD North Metropolitan Health Service Medical Director, Pediatric Intensive Care Unit Perth, Western Australia, Australia Pediatrics Memorial Sloan Kettering Cancer Center Saba Javed, MD Associate Professor of Clinical Pediatrics Assistant Professor Pediatrics Department of Anesthesiology Weill Cornell Medicine University of Texas Medical School at Houston New York, NY, USA Houston, TX, USA Samantha Koschel, BMed MD, GradDipAnat Bhawna Jha, MD, MRCPsych Urology Registrar Interventional Pain Physician Cancer Surgery Medical Director–Bundle Payment For Care Improvement Peter MacCallum Cancer Centre Physician Advisor–Utilization Management and Review Melbourne, Victoria, Australia University of Arkansas for Medical Sciences (UAMS) Little Rock, AR, USA Alan Kotin, MD Attending Anesthesiologist Shaman Jhanji, MB ChB, MRCP, FRCA, FFICM, PhD Anesthesiology Consultant in Intensive Care Medicine and Anaesthetics Memorial Sloan Kettering Cancer Center Department of Anaesthesia, Perioperative Medicine, Pain New York, NY, USA and Intensive Care Royal Marsden Hospital Atul Prabhakar Kulkarni, MBBS, MD (Anesthesiology) London, United Kingdom; Professor and Head Team Leader/Honorary Clinical Senior Lecturer Division of Critical Care Medicine Division of Cancer Biology Tata Memorial Hospital Institute of Cancer Research Homi Bhabha National Institute London, United Kingdom Mumbai, Maharashtra, India Daryl Jones, BSc(Hons), MB BS, FRACP, FCICM, MD, Adam La Caze, BPharm, BA (Hons), PhD PhD Senior Lecturer Consultant Intensive Care specialist School of Pharmacy Austin Health and Warringal hospital; The University of Queensland Acting Deputy Director Brisbane, Queensland, Australia Austin Department of Intensive Care; Adjunct Professor Nathan Lawrentschuk, MBBS, FRACS Urol, PhD University Melbourne; Professor Adjunct Professor (Research) Director of Urology DEPM Monash University; Royal Melbourne Hospital Medical Director Parkville, Victoria, Australia Critical Care Outreach Austin Hospital Past President Lauren Adrienne Leddy, MB, BCh, BAO International Society of Rapid Response Systems Medical Student Melbourne, Victoria, Australia Medicine University College Dublin Ravish Kapoor, MD Dublin, Ireland Associate Professor Department of Anesthesiology and Perioperative Medicine Celia R. Ledet, MD The University of Texas MD Anderson Cancer Center Assistant Professor Houston, TX, USA Department of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston, TX, USA