Concise and Enantioselective Total Syynthesis of (-)-Mehranine, (-)-Methylenebismehranine, and Related Asppidospperma Alkaloids Repporter: Zhongg Yan Checker: Xiang Gao Date: 2014/11/18 Movassaghi, M. et al. Angew. Chem. Int. Ed. 2014, 53, 11634. Movassaghi, M From MIT 1 (cid:139) Introduction (cid:139) Double-Cyclization Strategy in 2012 (cid:139)(cid:139) TTrraannssaannnnuullaarr-CCyycclliizzaattiioonn SSttrraatteeggyy iinn 22001144 (cid:139) Summary 2 Introduction 白白坚坚木木 马蹄花 3 Introduction 狗牙花 4 Double-Cyclization Strategy in 2012 Retrosynthetic Analysis: Double CCyycclliizzaattiioonn Movassaghi, M. et al. Angew. Chem. Int. Ed. 2012, 51, 4572. 5 Synthesis of Tryptamine Lactam 6 Synthesis of Tryptamine Lactam 7 Synthesis of Aspidosperma Alkaloid Double Cyclization 8 Transannular-Cyclization Strategy In 2014 Retrosynthetic Analysis: Transannular Cyclization Movassaghi, M. et al. Angew. Chem. Int. Ed. 2014, 53, 11634. 9 Transannular-Cyclization Strategy In 2014 10