mechaniosf amgesin g and development Mechanisms of Ageing and Development 115 (2000) 215-216 www.elsevier.com/locate/mechagedev Contents of volume 115 Volume 115 Nos. 1-2 May 18 2000 Distinct categories of immunologic changes in frail elderly J.L. Fahey, J.F. Schnelle, J. Boscardin, J.K. Thomas, M.E. Gorre, N. Aziz, H. Sadeghi, P. Nishanian (Los Angeles, CA; Reseda, CA) . . . Articular chondrocytes from aging rats respond poorly to insulin-like growth factor-1: an altered signaling pathway H. Messai, Y. Duchossoy, A.-M. Khatib, A. Panasyuk, D.R. Mitrovic (Paris, France; Moscow, Russia) Electrophysiological analysis of NMDA receptor subunit changes in the aging mouse cortex M.C. Kuehl-Kovarik, K.R. Magnusson, L.S. Premkumar, K.M. Partin (Ft. Collins, CO; Springfield, IL) Influence of short-term repeated fasting on the longevity of female (NZB x NZW)FI1 mice H. Sogawa, C. Kubo (Fukuoka, Japan) Kinetic studies of aflatoxin Bl-glutathione conjugate formation in liver and kidneys of adult and weanling rats A. Allameh, M. Farahani, A. Zarghi (Tehran, Iran) Immunohistochemical analysis of ageing human B and T cell populations reveals an age-related decline of CD8 T cells in spleen but not gut-asso- ciated lymphoid tissue (GALT) M. Banerjee, J.D. Sanderson, J. Spencer, D.K. Dunn-Walters (London, UK) Serum leptin response to endogenous hyperinsulinemia in aging rats A.D. Mooradian, J.M. Chehade (St Louis, MO) Whole-body metabolic rate appears to determine the rate of DNA oxida- tive damage and glycation involved in aging J.A. Greenberg, H. Wei, K. Ward, C.N. Boozer (New York, NY: Chicago, IL; New York, NY) 107 Volume 115 No. 3 Editorial Increased depolarization, prolonged recovery and reduced adaptation of the resting membrane potential in aged rat skeletal muscles following eccentric contractions T. McBride (Bakersfield, CA) 216 Contents of volume 115 Effects of aging on expression of genes involved in regulation of prolifera- tion and apoptosis in the colonic epithelium H.-M. Lee, G.H. Greeley, Jr, E.W. Englander (Galveston, TX)... . cDNA expression arrays reveal incomplete reversal of age-related changes in gene expression by calorie restriction E.-S. Han, $.G. Hilsenbeck, A. Richardson, J.F. Nelson (San Antonio, Changes in biological characteristics during the cellular aging of ligament fibroblasts derived from patients with prolapsus uteri M. Yamamoto, K. Akazawa, M. Aoyagi, K. Yamamoto (Tokyo, Overexpression of mRNAs of TGFB-1 and related genes in fibroblasts of Werner syndrome patients I. Ohsugi, O. Imamura, M. Satoh, M. Sugawara, M. Goto, M. Sugi- moto, Y. Furuichi (Kanagawa, Tokyo, Japan) Meeting report Author index Subject index Contents of volume 115