The objective of this book is to provide guidance for selecting the most appropriate options for safely managing solid waste generated at primary health care centres in developing countries. The main tool of this guide consists of six decision-trees aimed at assisting the user in identifying appropriate waste management methods. The guide takes into consideration the most relevant local conditions, the safety of workers and of the general public as well as of environmental criteria. This guide may also be used to evaluate existing practices related to health-care waste management. More detailed sources of information on handling and storage practices, technical options for treatment and disposal of wastes, training and personal protection, and assessment of a country's situation are also presented.