CONTENTS OF VOLUME 45 JANUARY 4, 20058 VOLUME 45 NUMBER 1 STATE-OF-THE-ART PAPER Viewpoint Should We Screen for Occult Coronary Artery Ximelagatran: Oral Direct Thrombin Inhibition as Disease Among Asymptomatic Patients With Anticoagulant Therapy in Atrial Fibrillation Diabetes? Marcelo F. Di Carli, Rory Hachamovitch Jonathan L. Halperin HEART FAILURE CLINICAL RESEARCH Apparently Normal Mitral Valves in Patients With Heart Failure Demonstrate Biochemical and Structural INTERVENTIONAL CARDIOLOGY Derangements: An Extracellular Matrix and Direct Stenting of Native De Novo Coronary Artery Echocardiographic Study K. Jane Grande-Allen, Allen G. Lesions With the Sirolimus-Eluting Stent: A Post Hoc Borowski, Richard W. Troughton, Penny L. Houghtaling, Subanalysis of the Pooled E- and C-SIRIUS Trials Nicholas R. DiPaola, Christine S. Moravec, Ivan Vesely, Michael Schliiter, Joachim Schofer, Anthony H. Gershlick, Brian P. Griffin Erick Schampaert, William Wins, Ginter Breithardt, for the E- and C-SIRIUS Investigators Editorial Comment Mitral Valve Abnormalities in Staged Initial Percutaneous Coronary Intervention Congestive Heart Failure: An Interplay Between Form Followed by Valve Surgery (“Hybrid Approach”) for and Function Kevin D. O’Brien, Daniel P. Fishbein Patients With Complex Coronary and Valve Disease John G. Byrne, Marzia Leacche, Daniel Unie, CARDIAC RESYNCHRONIZATION THERAPY James D. Rawn, Daniel I. Simon, Campbell D. Rogers, Ventricular Asynchrony Predicts a Better Outcome in Lawrence H. Cohn Patients With Chronic Heart Failure Receiving Cardiac Resynchronization Therapy ACUTE MYOCARDIAL INFARCTION Prognostic Implications of Elevated Troponin in Maria Vittoria Pitzalis, Massimo Iacoviello, Roberta Romito, Pietro Guida, Elisabetta De Tommasi, Patients With Suspected Acute Coronary Syndrome Giovanni Luzzi, Matteo Anaclerio, Cinzia Forleo, But No Critical Epicardial Coronary Disease: Paolo Rizzon A TACTICS-TIMI-18 Substudy Hisham Dokainish, Manu Pillai, Sabina A. Murphy, Peter M. DiBattiste, Marc Editorial Comment Cardiac Resynchronization Therapy J. Schweiger, Amir Lotfi, David A. Morrow, Christopher P. 101: If It’s Not Late, Pacing It Early Won’t Help Cannon, Eugene Braunwald, Nasser Lakkis, for the Anne B. Curtis TACTICS-TIMI-18 Investigators A Pharmacogenetic Effect of Factor XIII Valine 34 Leucine Polymorphism on Fibrinolytic Therapy for CARDIAC RHYTHM DISORDERS Trends in Implantable Cardioverter-Defibrillator Acute Myocardial Infarction Francisco Marin, Rocio Racial Disparity: The Importance of Geography Gonzalez-Conejero, Kaeng W. Lee, Javier Corral, Vanessa Peter W. Groeneveld, Paul A. Heidenreich, Alan M. Garber Roldan, Francisca Lopez, Francisco Sogorb, Juan Caturla, Gregory Y. H. Lip, Vicente Vicente Editorial Comment Care Disparities: Moving From Gray to Black and White John S. Rumsfeld, Eric D. Peterson ATHEROTHROMBOSIS An Increase of C-Reactive Protein Is Associated With Discordant Atrial Natriuretic Peptide and Brain Enhanced Activation of Endogenous Fibrinolysis at Natriuretic Peptide Levels in Lone Atrial Baseline But an Impaired Endothelial Fibrinolytic Fibrillation Patrick T. Ellinor, Adrian F. Low, Response After Venous Occlusion Walter Stefan Speidl, Kristen K. Patton, Marisa A. Shea, Calum A. MacRae Andrea Zeiner, Mariam Nikfardjam, Alexander Geppert, Nelli Jordanova, Alexander Niessner, Gerlinde Zorn, Gerald ECHOCARDIOGRAPHY Maurer, Wolfgang Schreiber, Johann Wojta, Kurt Huber Diastolic Dysfunction and Left Atrial Volume: CD40 Ligand Enhances Monocyte Tissue Factor A Population-Based Study Al/ison M. Pritchett, Expression and Thrombin Generation Via Oxidative Douglas W. Mahoney, Steven J. Jacobsen, Stress in Patients With Hypercholesterolemia Richard J. Rodeheffer, Barry L. Karon, Valerio Sanguigni, Domenico Ferro, Pasquale Pignatelh, Margaret M. Redfield Maria Del Ben, Tini Nadia, Mirella Saliola, Roberto Sorge, Francesco Viol Seven-Year Follow-Up After Dobutamine Stress Echocardiography: Impact of Gender on Prognosis DIABETES AND DETECTION OF CAD Elena Biagini, Abdou Elhendy, Jeroen J. Bax, Identifying High-Risk Asymptomatic Diabetic Patients Vittoria Rizzello, Arend F. L. Schinkel, Who Are Candidates for Screening Stress Single- Ron T. van Domburg, Miklos D. Kertat, Photon Emission Computed Tomography Imaging Boudewijn J. Krenning, Manolis Bountioukos, Navin Rajagopalan, Todd D. Miller, David O. Hodge, Claudio Rapezzi, Angelo Branzi, Maarten L. Simoons, Robert L. Frye, Raymond J. Gibbons Don Poldermans CARDIAC MAGNETIC RESONANCE CORRESPONDENCE Noninvasive Detection of Myocardial Fibrosis in RESEARCH CORRESPONDENCE Arrhythmogenic Right Ventricular Cardiomyopathy Absence of Acute Effects of Angiotensin II on Atrial Using Delayed-Enhancement Magnetic Resonance Electrophysiology in Humans Peter M. Kistler, Neil C. Imaging Hartkrishna Tandri, Manoj Saranathan, Rene Davidson, Prashanthan Sanders, Simon P. Fynn, Irene H. Rodriguez, Claudia Martinez, Chandra Bomma, Stevenson, Steven J. Spence, Jitendra K. Vohra, Paul B. Khurram Nasir, Boas Rosen, Joao A. C. Lima, Hugh Sparks, Jonathan M. Kalman Calkins, David A. Bluemke The Prognostic Importance of Body Mass Index After Noninvasive Assessment of Coronary Vasodilation Complicated Myocardial Infarction Linn M. A. Using Magnetic Resonance Angiography Masahiro Kennedy, Kenneth Dickstein, Stefan D. Anker, Krister Terashima, Craig H. Meyer, Brian G. Keeffe, EricJ . Putz, Kristianson, Ronnie Willenheimer, for the OPTIMAAL Erasmo de la Pena-Almaguer, Phillip C. Yang, Bob S. Hu, Study Group Dwight G. Nishimura, Michael V. McConnell Increased Skeletal Muscle Amino Acid Release With Light Exercise in Deconditioned Patients With Heart Failure Roberto Aquilani, Cristina Opasich, Maurizia YEAR IN CARDIOLOGY SERIES Dossena, Paolo Iadarola, Alessandra Gualco, Patrizia The Year in Valvular Heart Disease Arcidiaco, Simona Vigho, Federica Boschi, Manuela Verri, Shahbudin H. Rahimtoola Evasio Pasini LETTERS TO THE EDITOR Cautious Interpretation of Data Regarding EXPRESS PUBLICATIONS Myopericarditis Associated With Smallpox Diagnostic Accuracy of Noninvasive Coronary Imaging Vaccination Appor S. Gami, Joseph Murphy, Leslie T. Using 16-Detector Slice Spiral Computed Tomography Cooper Jr With 188 ms Temporal Resolution 4. Kuettner, REPLY Dimitri C. Cassimatis, J. Edwin Atwood, Renata T. Beck, T. Drosch, K. Kettering, M. Heuschmid, M. Engler, Peter E. Linz, Robert E. Eckart, C. Burgstahler, C. D. Claussen, A. F. Kopp, S. Schroeder Marina N. Vernalis, John D. Grabenstein Improved Diagnostic Accuracy With 16-Row Pacemaker Complication During Magnetic Resonance Multislice Computed Tomography Coronary Imaging Marc A. Rozner, Allen W. Burton, Ashok Kumar Angiography N. R. Mollet, F. Cademartiri, G. P. Krestin, REPLY James A. Coman, Edward T. Martin Eugene P. McFadden, C. A. Arampatzis, P. W. Serruys, Pim]. de Feyter Cardiopulmonary Exercise Testing in Patients With Heart Failure Robert L. Bard Transcatheter Cryoablation of Tachyarrhythmias in REPLY Michae/ Henein Children: Initial Experience From an International Registry Joe/ A. Kirsh, Gil J. Gross, Stephen O’Connor, Robert REPLY Pascal de Groote, Joél Dagorn, Benoit Soudan, M. Hamitton, for the Cryocath International Patient Registry Nicolas Lamblin, Eugene Mc Fadden, Christophe Bauters SCAI/SVMB/SVS CLINICAL HIGHLIGHTS FROM JACC IN 2004 COMPETENCE STATEMENT ON Highlights of the Year in JACC 2004 Anthony N. CAROTID STENTING DeMaria, Ori Ben-Yehuda, Daniel Berman, Gregory K. Clinical Competence Statement on Carotid Stenting: Feld, Barry H. Greenberg, James D. Knoke, Kirk U. Training and Credentialing for Carotid Stenting— Knowlton, Wilbur Y. W. Lew, Jagat Narula, David Sahn, Multispecialty Consensus Recommendations Sotirios Tsimtkas Kenneth Rosenfield, Chair JANUARY 18, 2005 VOLUME 45 NUMBER 2 STATE-OF-THE-ART PAPERS CLINICAL RESEARCH Cardiac Medical Therapy in Patients After INTERVENTIONAL CARDIOLOGY Undergoing Coronary Artery Bypass Graft Surgery: Predictive Factors for Ischemic Target Vessel A Review of Randomized Controlled Trials Revascularization in the Prevention of Restenosis Karen Okrainec, Robert Platt, Louise Pilote, With Tranilast and its Outcomes (PRESTO) Trial Mark J. Eisenberg Mandeep Singh, Bernard J. Gersh, Robyn L. McClelland, Kalon K. L. Ho, James T. Willerson, Wiliam F. Penny, Efficacy and Safety of High-Density Lipoprotein David R. Holmes, Jr Cholesterol-Increasing Compounds: A Meta- Analysis of Randomized Controlled Trials Rakesh S. Intravascular Ultrasound-Guided Treatment for Birjmohun, Barbara A. Hutten, John J. P. Kastelein, Erik S. Angiographically Indeterminate Left Main Coronary G. Stroes Artery Disease: A Long-Term Follow-Up Study Amir-Ali Fassa, Kenjt Wagatsuma, Stuart T. Higano, Katz, Linda Fried, Stephen Seliger, Anne Newman, David Verghese Mathew, Gregory W. Barsness, Ryan J. Lennon, Siscovick, Catherine Stehman-Breen David R. Holmes, Jr, Amir Lerman Detection of Embolic Particles With the Doppler ECHOCARDIOGRAPHY Guide Wire During Coronary Intervention in Patients Independent and Incremental Prognostic Value of With Acute Myocardial Infarction: Efficacy of Distal Early Mitral Annulus Velocity in Patients With Impaired Left Ventricular Systolic Function Mei Wang, Protection Device Afsunori Okamura, Hiroshi Ito, Katsuomt Iwakura, Shigeo Kawano, Koichi Inoue, Gabriel Yip, Cheuk-Man Yu, Qing Zhang, Yan Zhang, Yoshihiro Maekawa, Toshio Ogthara, Kenshi Fujii Deko Tse, Shun-Ling Kong, John E. Sanderson Pressure-Derived Measurement of Coronary Flow HEART RHYTHM DISTURBANCES Reserve Philip MacCarthy, Alexandre Berger, Heart Rate Turbulence After Atrial Premature Beats Ganesh Manoharan, Jozef Bartunek, Emanuele Barbato, Before Spontaneous Onset of Atrial Fibrillation Sai/a William Wins, Guy R. Heyndrickx, Nico H. J. Pils, Vikman, Kai Lindgren, Timo H. Maktkallio, Sinikka Bernard De Bruyne Yi-Mayry, K. E. Juhani Airaksinen, Heikki V. Hutkurt Pre-Existent Left Atrial Scarring in Patients CORONARY ARTERY DISEASE Health-Related Quality of Life After Interventional or Undergoing Pulmonary Vein Antrum Isolation: An Independent Predictor of Procedural Failure A¢u/ Conservative Strategy in Patients With Unstable Angina or Non-ST-Segment Elevation Myocardial Verma, Oussama M. Waznt1, Nassir F. Marrouche, David Infarction: One-Year Results of the Third Randomized O. Martin, Fethi Kilicaslan, Stephen Minor, Robert A. Schwetkert, Walid Saliba, Jennifer Cummings, J. David Intervention Trial of Unstable Angina (RITA-3) Joseph Kim, Robert A. Henderson, Stuart J. Pocock, Tim Clayton, Burkhardt, Mandeep Bhargava, William A. Belden, Ahmad Mark J. Sculpher, Keith A. A. Fox, for the RITA-3 Trial Abdul-Karim, Andrea Natale Investi gators PRECLINICAL RESEARCH Pregnancy-Associated Plasma Protein-A Levels in Patients With Acute Coronary Syndromes: Antagonism of Selectin Function Attenuates Comparison With Markers of Systemic Inflammation, Microvascular Platelet Deposition and Platelet- Mediated Myocardial Injury After Transient Ischemia Platelet Activation, and Myocardial Necrosis Christopher Heeschen, Stefanie Dimmeler, José A. Barrabés, David Garcia-Dorado, Maribel Mirabet, Javier Inserte, Luis Agullé, Bernat Soriano, Anna Christian W. Hamm, Stephan Fichtlscherer, Massaguer, Ferran Padilla, Rosa-Maria Lidén, Jordi Maarten L. Simoons, Andreas M. Zether, Soler-Soler for the CAPTURE Study Investigators Cellular and Ionic Mechanism for Drug-Induced Long Persistent Systemic Inflammation in Unstable Angina QT Syndrome and Effectiveness of Verapamil Takeshi Is Largely Unrelated to the Atherothrombotic Burden Aiba, Wataru Shimizu, Masashi Inagaki, Takashi Noda, Claudia Monaco, Elisabetta Rossi, Diego Milazzo, Franco Shunichiro Miyoshi, Wei-Guang Ding, Dimitar P. Zankov, Citterio, Francesca Ginnetti, Giuseppe D'Onofrio, Domentco Cianflone, Filippo Crea, Luigi M. Biasucet, Attilio Masert Futoshi Toyoda, Hiroshi Matsuura, Minoru Horie, Kenji Sunagawa Editorial Comment Another Look at the Age-Old Question: Which Came First, the Elevated C-Reactive EXPRESS PUBLICATIONS Protein or the Atherothrombosis? Marc S. Sabatine, Eugene Braunwald A Prospective Randomized Comparison Between Paclitaxel and Sirolimus Stents in the Real World of Interventional Cardiology Jean-Jacques Goy, ANTIPLATELET THERAPY Jean-Christophe Stauffer, Manon Siegenthaler, Alain Benoit, Variability in Platelet Responsiveness to Clopidogrel Charles Seydoux Among 544 Individuals Victor L. Serebruany, Steven R. Steinhubl, Peter B. Berger, Alex I. Malinin, Deepak L. Prevalence and Clinical Impact of Stent Fractures Bhatt, Eric J. Topol After Femoropopliteal Stenting Dierk Scheinert, Susanne Scheinert, Jacqueline Sax, Christopher Piorkowski, Sven HEART FAILURE Bréunlich, Matthias Ulrich, Giancarlo Biamino, What Resting Heart Rate Should One Aim for When Andrej Schmidt Treating Patients With Heart Failure With a Beta- Blocker? Experiences From the Metoprolol Controlled ACC NEWS Release/Extended Release Randomized Intervention President’s Page: The Future Is Now: ACC Goes to Trial in Chronic Heart Failure (MERIT-HF) Washington Michael J. Wolk Lars Gullestad, John Wikstrand, Prakash Deedwania, Ake Hyalmarson, Kenneth Egstrup, Uri Elkayam, Stephen CORRESPONDENCE Gottheb, Andrew Rashkow, Hans Wedel, Georgina Bermann, RESEARCH CORRESPONDENCE John Kjekshus, for the MERIT-HF Study Group Early Recovery of Impaired Coronary Flow Reserve by Contribution of Ischemic Mitral Regurgitation to Carvedilol Therapy in Patients With Idiopathic Congestive Heart Failure After Myocardial Infarction Dilated Cardiomyopathy: A Serial Transthoracic Francesco Grigiont, Delphine Detaint, Jean-Frangois Avierinos, Doppler Echocardiographic Study Kenichi Sugioka, Christopher Scott, Jamil Tajik, Maurice Enriquez-Sarano Takeshi Hozumi, Yasuhiko Takemoto, Keiji Ujino, Yoshiki Cystatin-C and Mortality in Elderly Persons With Matsumura, Hiroyuki Watanabe, Kohei Fujimoto, Minoru Heart Failure Michael G. Shlipak, Mark J. Sarnak, Ronit Yoshiyama, Junichi Yoshikawa Efficacy of A Patient-Activated Pharmacologic Pump REPLY Rad/ Moreno, Cristina Fernandez, Carlos Macaya Using Phenylephrine as Active Drug and Prodromal Symptoms as a Marker of Imminent Loss of Thrombolysis Should Be Regarded as First-Line Consciousness to Abort Tilt-Induced Syncope Therapy for Prosthetic Valve Thrombosis in the Antonio Raviele, Franco Giada, Gianni Gasparini Absence of Contraindications Maria Lengye/ Association of Smoking With Improved Myocardial REPLY Ann T. Tong, Raymond Roudaut, Mehmet Ozkan, Perfusion and the Angiographic Characterization of Alex Sagie, Maie S. A. Shahid, Sergio C. Pontes, Jr, Francesc Myocardial Tissue Perfusion Following Fibrinolytic Carreras, Steven E. Girard, Samir Arnaout, Raymond F. Therapy for ST-Segment Elevation Myocardial Staniback, Ravi Thadani, William A. Zoghbi, on behaloff Infarction Ajay J. Kirtane, Pedro Martinezclark, Aref M. the PRO-TEE Registry Investigators Rahman, Kausik K. Ray, Dimitrios Karmpahiotis, Sabina A. Murphy, Robert P. Giughano, Christopher P. Cardiologist in the Carotids Grayson H. Wheatley III Cannon, Elliott M. Antman, Matthew T. Roe, REPLY William A. Gray Robert A. Harrington, E. Magnus Ohman, Eugene Braunwald, C. Michael Gibson Advantage of Percutaneous Coronary Interventions LETTERS TO THE EDITOR Over Medical Therapy in Angina Relief and the Coronary Stenting Versus Balloon Angioplasty in Placebo Effect David Rott Small Vessels Pierfrancesco Agostini, Giuseppe G. L. Biondi-Zoccat, Antonio Abbate REPLY Whady Hueb, Paulo R. Soares, Eulégio Martinez FEBRUARY 1, 2005 VOLUME 45 NUMBER 3 STATE-OF-THE-ART PAPER Risk Factors for the Development of Retroperitoneal Use of Ultrasound Contrast Agents for Gene or Drug Hematoma After Percutaneous Coronary Intervention Delivery in Cardiovascular Medicine Raffi Bekeredjian, in the Era of Glycoprotein IIb/IIIa Inhibitors and Paul A. Grayburn, Ralph V. Shohet Vascular Closure Devices H. M. Omar Farouque, Jennifer A. Tremmel, Farshad Raissi Shabari, CLINICAL RESEARCH Meenakshi Aggarwal, William F. Fearon, Martin K. C. Ng, CLINICAL TRIALS Mehrdad Rezaee, Alan C. Yeung, David P. Lee Statins Decrease Perioperative Cardiac Complications Economic Effects of Prolonged Clopidogrel Therapy in Patients Undergoing Noncardiac Vascular Surgery: After Percutaneous Coronary Intervention The Statins for Risk Reduction in Surgery (StaRRS) Patricia A. Cowper, Krishna Udayakumar, Study Kristin O'Netl-Callahan, George Katsimaglis, Michael H. Sketch, Jr, Eric D. Peterson Micah R. Tepper, Jason Ryan, Carla Mosby, John P. A. Ioannidis, Peter G. Danias TREATMENT OF PATENT FORAMEN OVALE Multislice Computed Tomography Versus Intracardiac Transcatheter Treatment of Atrial Septal Aneurysm Echocardiography to Evaluate the Pulmonary Veins Associated With Patent Foramen Ovale for Prevention Before Radiofrequency Catheter Ablation of Atrial of Recurrent Paradoxical Embolism in High-Risk Fibrillation: A Head-to-Head Comparison Monique Patients Andreas Wahl, Ulrike Krumsdorf, Bernhard Meier, R. M. Jongbloed, Jeroen J. Bax, Hildo J. Lamb, Martin S. Horst Sievert, Stephan Ostermayer, Kai Billinger, Markus Dirksen, K. Zeppenfeld, Ernst E. van der Wall, Albert de Schwerzmann, Ulf Becker, Christian Seiler, Marcel Arnold, Roos, Martin J. Schalij Heinrich P. Mattle, Stephan Windecker INTERVENTIONAL CARDIOLOGY LEFT VENTRICULAR DYSFUNCTION Sirolimus-Eluting Stent Implantation for Unprotected Impact of Mitral Valve Annuloplasty on Mortality Left Main Coronary Artery Stenosis: Comparison Risk in Patients With Mitral Regurgitation and Left With Bare Metal Stent Implantation Seung-Jung Park, Ventricular Systolic Dysfunction Audrey H. Wu, Keith Young-Hak Kim, Bong-Ki Lee, Seung-Whan Lee, Cheol D. Aaronson, Steven F. Bolling, Francis D. Pagani, Kathy Whan Lee, Myeong-Ki Hong, Jae-Joong Kim, Gary S. Welch, Todd M. Koelling Mintz, Seong-Wook Park Editorial Comment Is Mitral Regurgitation a Viable Association of a Negative Residual Stenosis Following Treatment Target in Heart Failure? The Plot Just Rescue/Adjunctive Percutaneous Coronary Thickened Mandeep R. Mehra, Bartley P. Griffith Intervention With Impaired Myocardial Perfusion and Adverse Outcomes Among ST-Segment Elevation Angiotensin-Converting Enzyme Inhibitor as a Risk Myocardial Infarction Patients C. Michael Gibson, Ajay Factor for the Development of Anemia, and the J. Kirtane, Keith Boundy, Hung Ly, Dimitrios Karmpalitts, Impact of Incident Anemia on Mortality in Patients Sabina A. Murphy, Robert P. Giugliano, Christopher P. With Left Ventricular Dysfunction Areef Ishani, Cannon, Elhott M. Antman, Eugene Braunwald, for the Eric Weinhandl, Zihong Zhao, David T. Gilbertson, TIMI Study Group Allan J. Collins, Salim Yusuf, Charles A. Herzog HEART RHYTHM DISORDERS YEAR IN CARDIOLOGY SERIES The Impact of Implantable Cardioverter- The Year in Echocardiography Arthur E. Weyman Defibrillator Therapy on Survival in Autosomal- Dominant Arrhythmogenic Right Ventricular EXPRESS PUBLICATION Cardiomyopathy (ARVD5) Kathy A. Hodgkinson, Coronary Syndromes Following Aspirin Withdrawal: A Patrick 8. Parfrey, Anne S. Bassett, Christine Kupprion, Special Risk for Late Stent Thrombosis Emile Ferrari, Jérg Drenckhahn, Mark W. Norman, Ludwig Thierfelder, Mustapha Benhamou, Pierre Cerboni, Baudouy Marcel Susan N. Stuckless, Elizabeth L. Dicks, William J. McKenna, Sean P. Connors CORRESPONDENCE Editorial Comment Implantable Cardioverter- RESEARCH CORRESPONDENCE Defibrillator Therapy in Arrhythmogenic Right Fast Ventricular Tachycardias in Patients With Ventricular Cardiomyopathy: A Role for Genotyping Implantable Cardioverter-Defibrillators: Efficacy and in Decision-Making? Thomas Wichter, Safety of Antitachycardia Pacing: A Prospective and Ginter Breithardt Randomized Study Javier Jiménez-Candil, Angel Arenal, Current of Injury Predicts Adequate Active Lead Arcadio Garcia-Alberola, Mercedes Ortiz, Silvia del Castillo, Fixation in Permanent Pacemaker/Defibrillation Javier Fernandez-Portales, Juan Sanchez-Munoz, Juan Martinez-Sanchez, Esteban Gonzalez-Torrecilla, Felipe Leads SherryJ . Saxonhouse, Jamie B. Conti, Anne B. Curtis Atienza, Alberto Puchol, Jestis Almendral Outflow Tract Tachycardia With R/S Transition in Simvastatin Improves Endothelial Function in Patients Lead V,: Six Different Anatomic Approaches for With Rheumatoid Arthritis Frank Hermann, Adrian Successful Ablation Hildegard Tanner, Gerhard Forster, Rémy Chenevard, Frank Enseleit, David Hindricks, Petra Schirdewahn, Richard Kobza, Anja Hirlimann, Roberto Corti, Lukas E. Spieker, Diana Frey, Dorszewski, Christopher Piorkowski, Jin-Hong Gerds-L1, Matthias Hermann, Walter Riesen, Michel Neidhart, Hans Kottkamp Beat A. Michel, Jens P. Hellermann, Renate E. Gay, Thomas F. Liischer, Steffen Gay, Georg Noll, ECHOCARDIOGRAPHY Frank Ruschitzka Evaluation of Flow in the Left Anterior Descending Impact of Microvascular Complications on Outcome Coronary Artery But Not in the Left Internal After Coronary Stent Implantations in Patients With Mammary Artery Graft Predicts Significant Stenosis of Diabetes Carlo Briguori, Gerolama Condorelli, Flavio the Arterial Conduit Francesco Pizzuto, Paolo Voci, Atroldi, Fiore Manganelhi, Anna Violante, Amelia Focaccio, Enrica Mariano, Paolo Emilio Puddu, Alessandro Aprile, Bruno Ricctardelh, Antonio Colombo Francesco Romeo LETTERS TO THE EDITOR The Use of Live Three-Dimensional Doppler Hibernating Myocardium, Apoptosis, and a Simple Echocardiography in the Measurement of Cardiac Mathematical Task Antonio Abbate, Giuseppe Biondi- Output: An In Vivo Animal Study James Pemberton, Zoccat, Pierfrancesco Agostoni, Luigi M. Biasucct, Alfonso Xiaokut Li, Tara Karamlou, Chloe A. Sandquist, Karl Baldi, Filippo Crea Thiele, Irving Shen, Ross M. Ungerleider, Antoinette Kenny, REPLY Jutta Schaper, Albrecht Elsasser DavidJ . Sahn The Year in Congenital Heart Disease Warren G. Guntheroth CARDIAC MAGNETIC RESONANCE REPLY Thomas P. Graham, Jr Does Subclinical Hypothyroidism Affect Cardiac Pump Defibrillation Thresholds Testing of Implantable Performance? Evidence From a Magnetic Resonance Cardioverter-Defibrillators at Implantation Bharat K. Imaging Study Andrea Ripoli, Alessandro Pingitore, Kantharia Brunella Favili, Antonio Bottoni, Stefano Turch, Nael F. Osman, Daniele De Marchi, Massimo Lombard, REPLY Charles Swerdlow Antonio L’Abbate, Giorgio Iervasi ADVANCE Praise George A. Diamond REPLY Marco Valgimigh, Patrick W. Serruys HISTORY OF CARDIOLOGY CORRECTION A Note on the History of Cardiology: Dr. Otto Klein, 1881 to 1968 Sh/omo Stern CORRECTION FEBRUARY 1, 2005 VOLUME 45 NUMBER3 SUPPLEMENT A Featured Poster Presentations Special Topics Angiography and Interventional Cardiology Valvular Heart Disease Cardiac Arrhythmias Vascular Disease, Hypertension, and Prevention Cardiac Function and Heart Failure Young Investigators Awards Competition Myocardial Ischemia and Infarction Acknowledgments Noninvasive Imaging Author Index Pediatric Cardiology and Adult Congenital Heart Subject Index Disease FEBRUARY 15, 2005 VOLUME 45 NUMBER 4 STATE-OF-THE-ART PAPER INTERVENTIONAL CARDIOLOGY Reperfusion Strategies for Acute Myocardial Infarction Impact of Diabetes Mellitus on Myocardial Perfusion in the Elderly: Benefits and Risks Rajendra H. Mehta, After Primary Angioplasty in Patients With Acute Christopher B. Granger, Karen P. Alexander, Eduardo Myocardial Infarction Abhiram Prasad, Gregg W. Stone, Bossone, Harvey D. White, Michael H. Sketch, Jr Thomas D. Stuckey, Costantino O. Costantini, Peter J. Zimetbaum, Michael McLaughlin, Roxana Mehran, Eulogio Garcia, James E. Tcheng, David A. Cox, VIEWPOINT Cindy L. Grines, Alexandra J. Lansky, Bernard J. Gersh Drug-Eluting Stents for Diabetes Mellitus: A Rush to Judgment? Aloke V. Finn, Igor F. Palacios, Adnan Primary Angioplasty Is Cost-Minimizing Compared Kastrati, Herman K. Gold With Pre-Hospital Thrombolysis for Patients Within 60 Min of a Percutaneous Coronary Intervention Center: The Comparison of Angioplasty and Pre- CLINICAL RESEARCH Hospital Thrombolysis in Acute Myocardial Infarction CLINICAL TRIALS (CAPTIM) Cost-Efficacy Sub-Study Jacques Machecourt, Eric Bonnefoy, Gérald Vanzetto, Pascal Motreff, Stéphanie Effectiveness of Fludrocortisone and Salt in Preventing Marliére, Alain Letzorovicz, Benoit Allenet, Jean Michel Syncope Recurrence in Children: A Double-Blind, Lacroute, Jean Cassagnes, Paul Touboul Placebo-Controlled, Randomized Trial Mudbadda A. Salim, Thomas G. Di Sessa MINI-FOCUS: TRANSCATHETER CLOSURE OF ASD AND PFO ACUTE MYOCARDIAL INFARCTION Association of Interatrial Shunts and Migraine Antiarrhythmic Effect of Carvedilol After Acute Headaches: Impact of Transcatheter Closure Babak Myocardial Infarction: Results of the Carvedilol Post- Infarct Survival Control in Left Ventricular Dysfunction Azarbal, Jonathan Tobis, Wiliam Suh, Vicki Chan, Catherine Dao, Richard Gaster (CAPRICORN) Trial John McMurray, Lars Kober, Michele Robertson, Henry Dargie, Wilson Colucci, Jose Migraine Headache Relief After Transcatheter Closure Lopez-Sendon, Willem Remme, D. Norman Sharpe, of Patent Foramen Ovale Mark Reisman, Ryan D. Ian Ford Christofferson, Jill Jesurum, John V. Olsen, Merrill P. Spencer, Kimberly A. Krabill, Lance Diehl, Sheena Aurora, Editorial Comment Three Decades of Clinical Trials With William A. Gray Beta-Blockers: The Contribution of the CAPRICORN Editorial Comment Transcatheter Closure of Patent Trial and the Effect of Carvedilol on Serious Foramen Ovale for Migraine Prophylaxis: Hope or Arrhythmias Craig M. Pratt Hype? Sotirios Tsimikas Serial Analyses of N-Terminal Pro-B-Type Natriuretic Improvements in Cardiac Form and Function After Peptide in Patients With Non—ST-Segment Elevation Transcatheter Closure of Secundum Atrial Septal Acute Coronary Syndromes: A Fragmin and Fast Defects Omid Salehian, Eric Horlick, Markus Revascularisation During Instability in Coronary Schwerzmann, Kim Haberer, Peter McLaughlin, Samuel C. Artery Disease (FRISC)-II Substudy Berti/ Lindahl, Siu, Gary Webb, Judith Therrien Johan Lindback, Tomas Jernberg, Nina Johnston, Mats Long-Term Outcome of Transcatheter Secundum- Stridsberg, Per Venge, Lars Wallentin Type Atrial Septal Defect Closure Using Amplatzer Septal Occluders Jozef Masura, Pavol Gavora, Editorial Comment Warning! Context-Sensitive Data Tomaz Podnar Roger M. Mills CARDIAC IMAGING Kayita, Fumtyuki Shigeto, Etsuro Tanaka, Yoshiro Quantitative Measurement of Infarct Size by Contrast- Shinozaki, Hidezo Mort, Takahiko Kiyooka, Masashi Enhanced Magnetic Resonance Imaging Early After Katsura, Seitaro Ohkuma, Masami Goto, Yasuo Ogasawara, Acute Myocardial Infarction: Comparison With Fumihiko Kajtya Single-Photon Emission Tomography Using Tc”””- C-Type Natriuretic Peptide, a Novel Antifibrotic and Sestamibi Tareq Ibrahim, Stephan G. Nekolla, Mira Antihypertrophic Agent, Prevents Cardiac Remodeling Hornke, Hubertus P. Biilow, Josef Dirschinger, Albert After Myocardial Infarction Takeshi Soeki, Ichiro Schémig, Markus Schwaiger Kishimoto, Hiroyuki Okumura, Takeshi Tokudome, Takeshi Quantitative Relation Between Hemodynamic Changes Horio, Kenjt Mori, Kenji Kangawa During Intravenous Adenosine Infusion and the Magnitude of Coronary Hyperemia: Implications for MEETING HIGHLIGHTS Myocardial Perfusion Imaging Rakesh K. Mishra, Highlights of the 2004 Scientific Sessions of the Heart Sharmila Dorbala, Giridhar Logsetty, Alita Hassan, Therese Failure Society of America, Toronto, Canada, Heinonen, Heinrich R. Schelbert, Marcelo F. Di Carli, September 12 to 15, 2004 Peter Liu, Marvin A. Konstam, for the RAMPART Investigators Thomas Force Long-Term Safety of Intravascular Ultrasound in EDITOR’S PAGE Nontransplant, Nonintervened, Atherosclerotic Holiday Musings Anthony N. DeMaria Coronary Arteries Antoine Guédes, Pierre-Frédéric Keller, Philippe L. L’Alher, Jacques Lespérance, Jean Grégoire, ACC NEWS Jean-Claude Tardif President’s Page: Imaging: Not a Black and White Role of Collateral Blood Flow in the Apparent Issue Michael J. Wolk Disparity Between the Extent of Abnormal Wall Thickening and Perfusion Defect Size During Acute CORRESPONDENCE Myocardial Infarction and Demand Ischemia Howard Leong-Po1, Matthew P. Coggins, Jirt Sklenar, Ananda R. RESEARCH CORRESPONDENCE Jayaweera, Xin-Qun Wang, Sanjiv Kaul Relationship of Irreversible Myocardial Injury to Troponin I and Creatine Kinase-MB Elevation After HEART RHYTHM DISORDER Coronary Artery Bypass Surgery: Insights From Long-Term Efficacy of Cryo Catheter Ablation for the Cardiovascular Magnetic Resonance Imaging Joseph B. Treatment of Atrial Flutter: Results From a Repeat Sel/vanayagam, David Pigott, Lognathen Balacumaraswami, Electrophysiologic Study Annibale 8. Montenero, Nicola Steffen E. Petersen, Stefan Neubauer, David P. Taggart Bruno, Andrea Antonelli, Daniele Mangiamelt, Luca Atorvastatin Decreases Cellular Proliferation and Bone Barbieri, Peter Andrew, Olive Murphy, Stephen O'Connor, Matrix Expression in the Hypercholesterolemic Mitral Francesco Zumbo Valve Babu Makkena, Hani Salti, Malayannan Cryo-Ablation for Septal Tachycardia Substrates in Subramaniam, Senthil Thennapan, Robert H. Bonow, Frank Pediatric Patients: Mid-Term Results Aya Miyazaki, Caira, Robert O. Bonow, Thomas C. Spelsberg, Nalini M. Andrew D. Blaufox, David L. Fairbrother, J. Philip Saul Rajamannan LETTERS TO THE EDITOR SMOKING AND PLATELET FUNCTION Cardiac Resynchronization Therapy, Central Sleep Only Two-Week Smoking Cessation Improves Platelet Apnea, and Chyne-Stokes Respiration in Chronic Aggregability and Intraplatelet Redox Imbalance of Heart Failure Patients Christoph Scharf, Alexander Turk, Long-Term Smokers Hirohiko Morita, Hisao Ikeda, Thomas Brack, Konrad Bloch Nobuya Haramaki, Hiroyuki Eguchi, Tsutomu Imaizumi REPLY Christoph Stellbrink, Erik Skobel, Anil-Martin Sinha CONGENITAL HEART DISEASE Effects of Percutaneous Left Atrial Appendage Prevalence and Clinical Manifestations of 22q11.2 Transcatheter Occlusion (PLAATO) on Left Atrial Microdeletion in Adults With Selected Conotruncal Structure and Function Birke Schneider, Josef Finsterer, Anomalies Luc M. Beauchesne, Carole A. Warnes, Claudia Stéllberger Heidi M. Connolly, Naser M. Ammash, Martha Grogan, Syed M. Jalal, Virginia V. Michels REPLY Jdrahim R. Hanna, Peter C. Block Is Aspirin Resistance or Female Gender Associated PRECLINICAL RESEARCH With a High Incidence of Myonecrosis After Beneficial Effect of Hydroxyfasudil, a Specific Rho- Nonurgent Percutaneous Coronary Intervention? Tina Kinase Inhibitor, on Ischemia/Reperfusion Injury in S. Poulsen, Anders Kastrup, Hans Mickley Canine Coronary Microcirculation In Vivo Toyotaka REPLY Wai-Hong Chen, Pui-Yin Lee, William Neg, Yada, Hiroaki Shimokawa, Osamu Hiramatsu, Tatsuya Hung-Fat Tse, Chu-Pak Lau MARCH 1, 2005 VOLUME 45 NUMBER 5 STATE-OF-THE-ART PAPER Ahmad Abdul-Karim, Wilham A. Belden, Stephen Minor, The Epidemiology, Pathophysiology, and Management J. David Burkhardt, Walid Saliba, Robert A. Schweikert, of Psychosocial Risk Factors in Cardiac Practice: The Andrea Natale Emerging Field of Behavioral Cardiology A/an Rozanski, James A. Blumenthal, Karina W. Davidson, LVH AND ARRHYTHMIAS Patrice G. Saab, Laura Kubzansky Spectrum and Prognostic Significance of Arrhythmias on Ambulatory Holter Electrocardiogram in Hypertrophic Cardiomyopathy 4. Se/cuk Adabag, Susan CLINICAL RESEARCH A. Casey, Michael A. Kuskowski, Andrey G. Zenovtch, Barry J. Maron CORONARY ARTERY DISEASE Angioscopic Follow-Up Study of Coronary Ruptured 705 Cardiovascular Morbidity and Mortality in Plaques in Nonculprit Lesions Masamichi Takano, Hypertensive Patients With a History of Atrial Shigenobu Inami, Fumiyuki Ishibashi, Kentaro Okamatsu, Fibrillation: The Losartan Intervention for End Point Koji Seimiya, Takayoshi Ohba, Shunta Sakai, Reduction in Hypertension (LIFE) Study Kristian Kyoicht Mizuno Wachtell, Bjérn Hornestam, Mika Lehto, David J. Editorial Comment Plaque Rupture and Intracoronary Slotwiner, Eva Gerdts, Michael H. Olsen, Peter Aurup, Bjorn Dahléf, Hans Ibsen, Stevo Julius, Sverre E. Kjeldsen, Thrombus in Nonculprit Vessels: An Eyewitness Lars H. Lindholm, Markku S. Nieminen, Jens Rokkedal, Account John A. Ambrose, David J. D’Agate Richard B. Devereux HEART FAILURE Angiotensin II Receptor Blockade Reduces New-Onset Effects of Candesartan on Cardiac Sympathetic Nerve Atrial Fibrillation and Subsequent Stroke Compared to Activity in Patients With Congestive Heart Failure Atenolol: The Losartan Intervention for End Point and Preserved Left Ventricular Ejection Fraction Reduction in Hypertension (LIFE) Study Kristian Shu Kasama, Takuji Toyama, Hisao Kumakura, Yoshiaki Wachtell, Mika Lehto, Eva Gerdts, Michael H. Olsen, Byérn Takayama, Shuichi Ichikawa, Tadashi Suzuki, Hornestam, Bjorn Dahléf, Hans Ibsen, Stevo Julius, Sverre Masahiko Kurabayashi E. Kjeldsen, Lars H. Lindholm, Markku S. Nieminen, Richard B. Devereux Left Ventricular Assist Device Support Normalizes Left and Right Ventricular Beta~-Adrenergic Pathway Editorial Comment Angiotensin II Inhibition and Properties Stefan Klotz, Alessandro Barbone, Steven Prevention of Atrial Fibrillation and Stroke Retken, Jeffrey W. Holmes, Yoshifumi Naka, Mehmet C. Oz, Martial G. Bourassa Andrew R. Marks, Daniel Burkhoff CARDIAC IMAGING VENTRICULAR DYSSYNCHRONY A Prognostic Score for Prediction of Cardiac Mortality A Novel Tool to Assess Systolic Asynchrony and Risk After Adenosine Stress Myocardial Perfusion Identify Responders of Cardiac Resynchronization Scintigraphy Rory Hachamovitch, Sean W. Hayes, John D. Therapy by Tissue Synchronization Imaging Friedman, Ishac Cohen, Daniel S. Berman Cheuk-Man Yu, Qing Zhang, Jeffrey Wing-Hong Fung, Editorial Comment Quantitative Instruments for Hamish Chi-Kin Chan, Yat-Sun Chan, Predicting Risk... and Benefit James FE. Udelson, Gabriel Wai-Kwok Yip, Shun-Ling Kong, Hong Lin, Harry P. Selker Yan Zhang, John E. Sanderson Effect of Lipid-Lowering Therapy With Atorvastatin on Atherosclerotic Aortic Plaques Detected by This article has accompanying videos that can be Noninvasive Magnetic Resonance Imaging A¢sushi viewed on the Internet (March 1 issue of JACC) at: http://www.onlinejacc.org Yonemura, Yukihiko Momiyama, Zahi A. Fayad, Makoto Ayaort, Retko Ohmori, Kenji Higashi, Teruyoshi Kihara, Shojtro Sawada, Noriyuki Iwamoto, Masatsune Ogura, Cross-Sectional Relations of Electrocardiographic Hiroaki Taniguchi, Masatoshi Kusuhara, Masayoshi Nagata, QRS Duration to Left Ventricular Dimensions: The Haruo Nakamura, Setichi Tamai, Fumitaka Ohsuzu Framingham Heart Study Ravi Dhingra, Byung Ho Noninvasive Diagnosis of Coronary Artery Disease in Nam, Emelia J. Benjamin, Thomas J. Wang, Martin G. Patients With Heart Failure and Systolic Dysfunction Larson, Ralph B. D'Agostino, Sr, Daniel Levy, of Uncertain Etiology, Using Late Gadolinium- Ramachandran S§. Vasan Enhanced Cardiovascular Magnetic Resonance Car/os /. Soriano, Francisco Ridocci, Jordi Estornell, Javier Jimenez, HEART RHYTHM DISORDERS Vicente Martinez, José A. De Velasco The Need for Atrial Flutter Ablation Following Pulmonary Vein Antrum Isolation in Patients With Noninvasive Visualization of the Cardiac Venous and Without Prior Cardiac Surgery Fethi Kilicas/an, System Using Multislice Computed Tomography Atul Verma, Hirosuke Yamajit, Nassir F. Marrouche, Monique R. M. Jongbloed, Hildo J. Lamb, Jeroen J. Bax, Oussama Wazni, Jennifer E. Cummings, Steven Hao, Joanne D. Schuyf, Albert de Roos, Ernst E. van der Wall, Michelle Wiliams Andrews, Salwa Beheiry, Martin J. Schaly ECHOCARDIOGRAPHY ACC NEWS The Quantification of Absolute Myocardial Perfusion Newly Elected Members of the College in Humans by Contrast Echocardiography: Algorithm and Validation Ro/f Vogel, Andreas Indermiihle, Jessica Reinhardt, Pascal Meter, Patrick T. Siegrist, Mehdi CORRESPONDENCE Namdar, Philipp A. Kaufmann, Christian Seiler RESEARCH CORRESPONDENCE Quantitation of Mitral Valve Tenting in Ischemic Angiographic Patterns of Restenosis After Paclitaxel- Mitral Regurgitation by Transthoracic Real-Time Eluting Stent Implantation Joannis lakovou, Thomas Three-Dimensional Echocardiography Nozomi Schmidt, Let Ge, Giuseppe M. Sangiorgi, Goran Stankovic, Watanabe, Yasuo Ogasawara, Yasuko Yamaura, Takahiro Flavio Airoldi, Alaide Chieffo, Matteo Montorfano, Mauro Kawamoto, Eyjit Toyota, Takashi Akasaka, Kiyoshi Yoshida Carlino, lassen Michev, Nicola Corvaja, John Cosgrave, Broad-Beam Spectral Doppler Sonification of the Vena Ulrich Gerckens, Eberhard Grube, Antonio Colombo Contracta Using Matrix-Array Technology: A New Solution for Semi-Automated Quantification of Mitral LETTERS TO THE EDITOR Regurgitant Flow Volume and Orifice Area Thomas Rescue Angioplasty—The MERLIN Trial Andrew G. Buck, Bjorn Plicht, Peter Hunold, Ronald A. Mucci, C. Sutton, Mark A. de Belder Raimund Erbel, Robert A. Levine REPLY Cindy L. Grines, William O'Neill PRECLINICAL RESEARCH Definition of Failed Lysis May Have Influenced Detection of Peripheral Vascular Stenosis by Assessing Outcome in the MERLIN Trial Faize/ Osman, Amer Skeletal Muscle Flow Reserve Thanjuvar Bragadeesh, Chit, Peter E. Glennon Ibrahim Sari, Marco Pascotto, Antonio Micari, Sanjiv Kaul, REPLY Andrew G. C. Sutton, Mark A. de Belder Jonathan R. Lindner Better Outcome After Pediatric Defibrillation Dosage Influence of Pretreatment Systolic Blood Pressure on Than Adult Dosage in a Swine Model of Pediatric Benefit From Carvedilol in Severe Chronic Heart Ventricular Fibrillation Robert A. Berg, Ricardo A. Failure Patients Ja/a/ K. Ghali Samson, Marc D. Berg, Fred W. Chapman, Ronald W. REPLY Jay N. Cohn Hilwig, Isabelle Banville, Robert G. Walker, Richard C. Nova, Nathan Anavy, Karl B. Kern REPLY Jean Rouleau YEAR IN CARDIOLOGY SERIES Should the Lack of Feasibility of Conducting The Year in Clinical Electrophysiology Controlled Trials Influence Evidence-Based Melvin M. Scheinman, Edmund Keung Guidelines? Kenneth M. Kessler REPLY Lori Mosca MEETING HIGHLIGHTS Highlights of the 2004 Transcatheter Cardiovascular Therapeutics (TCT) Annual Meeting: Clinical CORRECTION Implications Ehtisham Mahmud, Babek Pezeshki, CORRECTION Ali Salami, Shahin Keramati MARCH 15, 2005 VOLUME 45 NUMBER 6 STATE-OF-THE-ART PAPER Angina Patients Suppress Adverse Outcomes With Recent Hypertension Trials: Implications and Early Implementation of the American College of Controversies Bryan Williams Cardiology/American Heart Association Guidelines) National Quality Improvement Initiative Andra L. CLINICAL RESEARCH Blomkalns, Anita Y. Chen, Judith §. Hochman, Eric D. Peterson, Kelly Trynosky, Deborah B. Diercks, Gerard X. ACUTE CORONARY SYNDROMES Brogan, Jr, Wiliam E. Boden, Matthew T. Roe, E. Magnus Gender and Myocardial Salvage After Reperfusion Ohman, W. Brian Gibler, L. Kristin Newby, Treatment in Acute Myocardial Infarction Ju/inda for the CRUSADE Investigators Mehilli, Gjin Ndrepepa, Adnan Kastrati, Stephan G. Nekolla, Christina Markwardt, Hildegard Bollwein, Long-Term Cost-Effectiveness of Clopidogrel Given Jiirgen Pache, Stefan Martinoff, Josef Dirschinger, for Up to One Year in Patients With Acute Coronary Markus Schwaiger, Albert Schémig Syndromes Without ST-Segment Elevation Gender Disparities in the Diagnosis and Treatment of William S. Weintraub, Elizabeth M. Mahoney, Non-ST-Segment Elevation Acute Coronary Andre Lamy, Steven Culler, Yong Yuan, Jaime Caro, Syndromes: Large-Scale Observations From the Sylvie Gabriel, Salim Yusuf, on behalf of the CURE Study CRUSADE (Can Rapid Risk Stratification of Unstable Investigators ATHEROSCLEROSIS CARDIAC PACEMAKERS Does Shear Stress Modulate Both Plaque Progression Clinical Study of Interference With Cardiac and Regression in the Thoracic Aorta? Human Study Pacemakers by a Magnetic Field at Power Line Using Serial Magnetic Resonance Imaging /Jo/anda /. Frequencies Alexandre Trigano, Olivier Blandeau, Martine Wentzel, Roberto Corti, Zahi A. Fayad, Paul Wisdom, Souques, Jean Pierre Gernez, Isabelle Magne Frank Macaluso, Mark O. Winkelman, Valentin Fuster, JuanJ . Badimon CARDIAC IMAGING Late Gadolinium-Enhanced Magnetic Resonance Imaging in Acute and Chronic Myocardial Infarction: HEART FAILURE Improved Prediction of Regional Myocardial Effect of Perindopril on the Onset and Progression of Contraction in the Chronic State by Measuring Left Ventricular Dysfunction in Duchenne Muscular Thickness of Nonenhanced Myocardium Yasutaka Dystrophy Denis Duboc, Christophe Meune, Guy Lerebours, Ichikawa, Hajime Sakuma, Naohisa Suxawa, Kakuya Jean-Yves Devaux, Guy Vaksmann, Henri-Marc Bécane Kitagawa, Katsutosht Makino, Tadanort Hirano, Kan Takeda Editorial Comment Did They Lower Stress in the Trial? Or Was It Just Wasted Energy? Stephen P. Sanders CARDIOVASCULAR EFFECTS OF TOBACCO Hemodynamic and Autonomic Effects of Smokeless Tobacco in Healthy Young Men Robert Wolk, Abu S. ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA M. Shamsuzzaman, Anna Svatikova, Christine M. Huyber, Echocardiographic Findings in Patients Meeting Task Corey Huck, Krzysztof Narkiewtcz, Virend K. Somers Force Criteria for Arrhythmogenic Right Ventricular Dysplasia: New Insights From the Multicenter Study CONGENITAL HEART DISEASE of Right Ventricular Dysplasia Danita M. Yoerger, Frank 915 Detection of Left Ventricular Asynchrony in Patients Marcus, Duane Sherrill, Hugh Calkins, Jeffery A. Towbin, With Right Bundle Branch Block After Repair of Wojciech Zareba, Michael H. Picard, for the Tetralogy of Fallot Using Tissue-Doppler Imaging- Multidisciplinary Study of Right Ventricular Dysplasia Derived Strain Mohamed Y. Abd El Rahman, Wei Hui, Investigators Moustafa Yigitbasi, Fatima Dsebissowa, Stephan Schubert, Editorial Comment Echocardiographic Findings and the Roland Hetzer, Peter E. Lange, Hashim Abdul-Khaliq Search for a Gold Standard in Patients With Arrhythmogenic Right Ventricular Dysplasia HYPERTROPHIC CARDIOMYOPATHY Melvin M. Scheinman, Michael H. Crawford Adenosine Monophosphate-Activated Protein Kinase Disease Mimicks Hypertrophic Cardiomyopathy and Wolff-Parkinson-White Syndrome: Natural History ABLATION OF ATRIAL FIBRILLATION Ross T. Murphy, Jens Mogensen, Kate McGarry, Ajay Bahl, Transcatheter Radiofrequency Ablation of Atrial Alison Evans, Eyman Osman, Petros Syrris, Grainne Fibrillation in Patients With Mitral Valve Prostheses Gorman, Michael Farrell, Janice L. Holton, Michael G. and Enlarged Atria: Safety, Feasibility, and Efficacy Hanna, Sian Hughes, Perry M. Elhott, Calum A. MacRae, Christopher C. Lang, Vincenzo Santinelli, Giuseppe Augello, WilhamJ . McKenna Amedeo Ferro, Filippo Gugliotta, Simone Gulletta, Gabriele Vicedomini, Cézar Mesas, Gabriele Paglino, Simone Sala, PRECLINICAL RESEARCH Nicoleta Sora, Patrizio Mazzone, Francesco Manguso, Prior Exercise Training Improves the Outcome of Carlo Pappone Acute Myocardial Infarction in the Rat: Heart Structure, Function, and Gene Expression Sari¢ Role of Transtelephonic Electrocardiographic Freimann, Mickey Schetnowitz, Daniel Yekutielt, Micha S. Monitoring in Detecting Short-Term Arrhythmia Feinberg, Michael Eldar, Gania Kessler-Icekson Recurrences After Radiofrequency Ablation in Patients With Atrial Fibrillation Gaetano Senatore, Giuseppe Editorial Comment Benefit of an Exercise Program Before Stabile, Emanuele Bertaglia, Giovanni Donnici, Antonio De Myocardial Infarction Robert A. Kloner, Simone, Franco Zoppo, Pietro Turco, Pietro Pascotto, Boris Z. Simkhovich Massimo Fazzari EXPEDITED REVIEWS What Is the Risk of Stent Thrombosis Associated VENTRICULAR TACHYCARDIA With the Use of Paclitaxel-Eluting Stents for Idiopathic Ventricular Arrhythmia Arising From the Percutaneous Coronary Intervention? A Meta- Mitral Annulus: A Distinct Subgroup of Idiopathic Analysis Anthony A. Bavry, Dharam J. Kumbhani, Ventricular Arrhythmias Hiroshi Tada, Sachiko Ito, Thomas J. Helton, Deepak L. Bhatt Shigeto Naito, Kenji Kurosaki, Shoichi Kubota, Aiko Thirty-Day Incidence and Six-Month Clinical Sugtyasu, Taketsugu Tsuchiya, Kohei Miyaji, Outcome of Thrombotic Stent Occlusion After Bare- Minoru Yamada, Yasunori Kutsumi, Shigeru Oshima, Metal, Sirolimus, or Paclitaxel Stent Implantation Akihiko Nogami, Koichi Taniguchi Andrew T. L. Ong, Angela Hoye, Jiro Aoki, Carlos A. G. Electrocardiographic and Electrophysiologic van Mieghem, Gaston A. Rodriguez Granillo, Characteristics of Ventricular Tachycardia Originating Karel Sonnenschein, Evelyn Regar, Eugene P. Mckadden, Within the Pulmonary Artery Yukio Sekiguchi, Kazutaka Georgios Sianos, Willem J. van der Giessen, Aonuma, Atsushi Takahashi, Yasuteru Yamauchi, Hitoshi Peter P. T: de Jaegere, Pim de Feyter, Hachtya, Yasuhiro Yokoyama, Yoshito Iesaka, Mitsuaki Isobe Ron T. van Domburg, Patrick W. Serruys