EXPO 2015 I botanicals per la nutrizione e la salute: dal protocollo di Nagoya alla cooperazione internazionale WORKSHOP SU INTEGRATORI ALIMENTARI Milano, 13. Luglio 2015 Herbal Medicinal Products and Feed Additives in Veterinary Medicine and Animal Nutrition I botanicals nella medicina veterinaria e nell'alimentazione animale Prof.em. Ch. FRANZ, Univ. of Veterinary Medicine Vienna Activity, use and application of Functional Plant Products Christaki et al., 2012 Agriculture 2 228-243 Functional Plant Products / Secondary Metabolites Pharmaceutical Food / Feed Use: use: EFFICACY! SAFETY first! Food Herbal Medical Feed Supplements Medicinal Devices Dietary Additives Products etc. Products,… Feed Additives / Medicinal Products Integrators Guideline 2004/28/EU (Community Codex Veterinary Drugs) Regulation (EU) 1831/2003 Directive (EU) 726/2004 (Human- & Directive (EU) 834/2007, 889/2008 Veterinary Medicinal Products) Guideline (EU) 429/2008 Directive (EU) 834/2007, 889/2008 (Organic Production) Farm Animals Horses and Dir. (EU) 2377/90 (MRL-Values) Companion Animals Dir. (EU) 834/2007 and 889/2008 (Organic Production) (Feed Additives: also EFSA responsible!) Pferd Franz et al. 2010, FFJ 25, 327 Herbal Medicinal Products in Veterinary Medicine • ~ 20 registered products in Austria • ~ 30 registered products in Switzerland • ~ 30 registered products in Germany • ? In other countries ? • Alternative products: • dietetics, integrators, appetizers, ‚cosmetics‘, ‚…health care products‘ etc. …. =„parafarmaceutics“ Survey on Herbal Medicinal Products and Feed Additives / Dietary Products for Animals in Austria (MSc Theses Vetmeduni Vienna 2012) Species HMPs Feed Additives Calendula officinalis 3 - Crataegus oxyacantha - (!) 2 Cynara scolymus/ - 5 Echinacea sp. 3 3 Harpagophytum procumbens - (!) 4 Hypericum perforatum - (!) 4 Matricaria recutita 2 5 Panax ginseng 1 3 Silybum marianum - (!) 4 Thymus vulgare - 6 Valeriana officinalis - (!) 4 Zingiber officinale - 3 Medicinal plants traditionally used to treat different disturbances of ruminants H/ D M R S U G Plant species C Pimp. anisum + ++ ++ Arnica mont. ++ (+) (+) (+) (+) Althaea off. + ++ + ++ (+) (+) ++ Quercus robur ++ + + ++ ++ Gentiana lutea (+) (+) (+) (+) (+) ++ Foenicul. vulg. (+) (+) + ++ + (+) ++ Vacc. myrtillus (+) ++ D:skin, H/C:.heart/circulation, M:mamma/udder, R:respiratory tract, S: sensory organs, U: urogenital tract, G: gastrointestinal tract • Laudato M, Capasso R.: Useful plants for animal therapy. OA Alternative Medicine 2013, Feb. 01; 1(1)1. OA Publ. London • „…in this paper we have reviewed the herbal drugs most commonly utilized in domestic animals.“ • Cardiovascular system; Skin; Helminthiasis; Digestive apparatus; Respiratory app.; Reproductive app.; Additional uses (mastitis, milk production; Dogs and Cats: antiinflamm., anxiety, immunostimulants,…) • 45 plant species mentioned, from Allium sativum to Zingiber officinale, • 29 literature citations Functional Products from Officinal Plants used in Veterinary Medicine • Companion Animals and Horses • Tendency towards natural products in complementary medicine • Farm Animals / Animal Fattening • Crisis of the food industry: mismanagement within the mass propagation of animals