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Customer Service Department 63 Great Road Maynard, MA 01754 USA (cid:11)1.800.986.6008 (cid:22) 978.897.5462 (cid:29) Web www.chiscientific.com Table of Contents Abbreviations ...................................................................................................................................3 N-Protecting Reagents.....................................................................................................................6 Peptide Coupling Reagents..............................................................................................................8 Linkers for Solid Phase Synthesis.................................................................................................11 Other Reagents...............................................................................................................................12 Amino Acids and Derivatives ........................................................................................................15 Unusual Amino Acids....................................................................................................................36 N-Methyl Amino Acids...................................................................................................................51 Boc-Amino Acids and Derivative ..............................................................................................54 Fmoc-Amino Acids and Derivatives..............................................................................................64 Z-Amino Acids and Derivatives.....................................................................................................76 Amino Alcohols..............................................................................................................................82 Fmoc-Amino Acids Attached to Wang Resin................................................................................88 Amino Acids 2-Chlorotrityl Resin.................................................................................................91 Other Resin and Derivatives..........................................................................................................94 Pharmaceutical Peptide.................................................................................................................97 Cosmetic peptide..........................................................................................................................101 Catalogue Peptides.......................................................................................................................102 Honeywell Burdick & Jackson Solvent......................................................................................173 Mass Spectrometry Analysis........................................................................................................174 Custom Peptide Synthesis............................................................................................................175 Alphabetical Index.......................................................................................................................177 Custom Synthesis & Manufacturing...........................................................................................192 Ordering Information..................................................................................................................194 2 ASK FOR OTHER QUANTITIES CHI Scientific Abbreviations Abbreviations Symbol Structure Name Formula MW O Acm C Acetamidomethyl C H ON 72.1 H C N 3 6 3 H O Z O Benzyloxycarbonyl C H O 135.1 (CBZ) 8 7 2 CH O 3 Boc H C O C t-Butoxycarbonyl C H O 101.1 3 5 9 2 CH 3 CH 3 tBu H C t-Butyl C H 57.1 3 4 9 CH 3 OMe DMT 4,4’-Dimethoxytrityl C H O 303.3 MeO 21 19 2 O Fmoc O Fluorenylmethoxy-carbonyl C H O 223.3 15 11 2 H C 3 CH 3 H C O 2,2,4,6,7- 3 Pbf O S Pentamethyldihydrobenzofu C H O S 253.3 13 17 3 O ran-5-sulfonyl H C CH 3 3 Trt Trityl C H 243.3 19 15 ASK FOR OTHER QUANTITIES 3 Abbreviations CHI Scientific Symbol Structure Name Formula MW NH 2 OH Alanine Ala C H NO 89.1 3 7 2 O NH H 2 Arginine H N N OH Arg 2 C6H14N4O2 174.2 NH O O NH 2 OH Asparagine Asn C H N O 132.1 H2N 4 8 2 3 O O NH 2 Aspartic acid OH Asp C H NO 133.1 HO 4 7 4 O NH 2 Citrulline H N NH Cit 2 COOH C6H13N3O3 175.2 O NH 2 Cysteine HS OH Cys C H NO S 121.2 3 7 2 O NH 2 OH Glutamic acid Glu C H NO 147.1 HOOC 5 9 4 O NH 2 Glutamine H N OH Gln 2 C5H10N2O3 146.2 O O OH Glycine H N Gly 2 C2H5NO2 75.07 O O Histidine His HN OH C6H9N3O2 155.2 N NH2 CH O 3 H C OH Isoleucine Ile 3 C H NO 131.2 6 13 2 NH 2 4 ASK FOR OTHER QUANTITIES CHI Scientific Abbreviations Symbol Structure Name Formula MW O H C Leucine Leu 3 OH C6H13NO2 131.2 CH NH 3 2 O H N Lysine Lys 2 OH C6H14N2O2 146.2 NH 2 NH 2 Methionine Met H C OH C H NO S 149.2 3 S 5 11 2 O NH 2 OH Phenylalanine Phe C H NO 165.2 9 11 2 O NH 2 H N OH Ornithine Orn 2 C H N O 132.1 5 12 2 2 O O Proline Pro OH C H NO 115.1 5 9 2 N H O Serine Ser HO OH C3H7NO3 105.1 NH 2 O Threonine Thr HO OH C4H9NO3 119.1 NH 2 NH 2 OH Tryptophan Trp C H N O 204.2 O 11 12 2 2 N H NH 2 OH Tyrosine Tyr C H NO 181.2 HO 9 11 3 O O Valine Val OH C5H11NO2 117.1 NH 2 ASK FOR OTHER QUANTITIES 5 N-protecting Reagents CHI Scientific N-Protecting Reagents Cat # Product MW QTY US $ 5-70129 9-Fluorenylmethanol, 99%min. 196.2 50g 20.00 5-70130 [24324-17-2] 100g 30.00 C H O 14 11 5-70137 Boc Anhydride, 99%min. 218.3 100ml 25.00 5-70138 [24424-99-5] 500ml 100.00 C H O 10 18 5 5-70141 CBZ-Cl (Z-Cl), 95%min. 170.6 100ml 28.00 5-70142 [501-53-1] 500ml 88.00 C H ClO 8 7 2 5-70372 CBZ-OSu (Z-OSu), 98%min. 249.2 50g 27.00 5-70373 [13139-17-8] 100g 43.00 C H NO 12 11 5 5-70163 DMT-Cl, 98%min. 338.8 25g 30.00 5-70164 [40615-36-9] 100g 90.00 C H ClO 21 19 2 5-70167 DSC, N,N’-Disuccinimidyl 256.2 25g 72.00 5-70168 carbonate 100g 214.00 [74124-79-1] C H N O 9 8 2 7 5-70172 Fmoc-Cl, 97%min. 258.7 25g 22.00 5-70173 [28920-43-6] 100g 67.00 C H ClO 15 11 2 5-41000 Fmoc-NH 239.3 25g 133.85 2 5-41001 [84418-43-9] 100g 406.93 C H NO 15 13 2 5-70188 Fmoc-OSu, 98%min. 337.3 50g 24.00 5-70189 [82911-69-1] 100g 30.00 C H NO 19 15 5 5-70228 Z(2-Cl)-OSu, 99%min. 283.7 25g 32.00 5-70229 [65853-65-8] 100g 115.00 C H ClNO 12 10 5 5-70226 Z(2-Br)-OSu, 99%min. 328.1 25g 32.00 5-70227 [128611-93-8] 100g 115.00 C H BrNO 12 10 5 6 ASK FOR OTHER QUANTITIES CHI Scientific N-protecting Reagents Cat # Product MW QTY US $ 5-70206 tert-Butyldimethylsilyl Chloride 150.7 100g 24.00 5-70207 98% min. 250g 48.00 [18162-48-6] C H ClSi 6 15 5-70220 Trityl Chloride, 98%min. 278.8 100g 22.00 5-70221 [76-83-5] 250g 44.00 C H Cl 19 15 FFoorr bbuullkk qquuaannttiittiieess,, CCHHII SScciieennttiiffiicc iiss eessppeecciiaallllyy rreeccoommmmeennddeedd.. ASK FOR OTHER QUANTITIES 7 Peptide Coupling Reagents CHI Scientific Peptide Coupling Reagents Cat # Product MW QTY US $ 5-70139 BOP reagent, 99% min. 442.3 25g 24.00 5-70140 [56602-33-6] 100g 72.00 C H F N OP 12 22 6 6 2 5-70143 CDI, 98%min. 25g 30.00 162.2 5-70144 N,N’-Carbonyldiimidazole 50g 45.00 [530-62-1] C H N O 7 6 4 5-70153 DCC, 98%min. 100g 14.00 206.3 5-70154 N,N’-Dicyclohexylcarbodiimide 500g 57.00 [538-75-0] C H N 13 22 2 5-70155 DEPBT 299.2 25g 111.00 5-70156 3-(Diethoxy-phosphoryloxy)-3H- 100g 333.00 benzo[d][1,2,3] triazin-4-one [165534-43-0] C H N O P 11 14 3 5 5-70159 DIC, 99%min. 126.2 100ml 70.00 5-70160 N,N’-Diisopropylcarbodiimide 500ml 290.00 [693-13-0] C H N 7 14 2 5-70169 EDC•HCl, 99%min. 191.7 25g 44.00 5-70170 [25952-53-8] 100g 131.00 C H N ·HCl 8 17 3 5-70174 HATU, 99% min. 380.2 5g 30.00 5-70175 [148893-10-1] 25g 118.00 C H F N OP 10 15 6 6 5-70176 HBTU, 99% min. 50g 30.00 379.2 5-70177 [94790-37-1] 100g 46.00 C H F N OP 11 16 6 5 5-70182 HOAt, 99% min. 25g 115.00 136.1 5-70183 [39968-33-7] 100g 288.00 C H N O 5 4 4 8 ASK FOR OTHER QUANTITIES CHI Scientific Peptide Coupling Reagents Cat # Product MW QTY US $ 5-70184 HOBt (anhydrous), 99%min. 100g 17.00 135.1 5-70185 [2592-95-2] 500g 68.00 C H N O 6 5 3 5-70186 HOOBt, 99%min. 25g 73.00 163.1 5-70187 [28230-32-2] 100g 217.00 C H N O 7 5 3 2 5-41002 HCTU 25g 167.32 413.8 5-41003 [330645-87-9] 100g 508.66 C H ClF N OP 11 15 6 5 5-70147 Cl-HOBt, 99% min. 25g 80.00 169.6 5-70148 [26198-19-6] 100g 280.00 C H ClN O 6 4 3 5-70194 PyBOP, 99% min. 25g 60.00 520.4 5-70195 [128625-52-5] 100g 128.00 C H F N OP 18 28 6 6 2 5-70196 PyBrOP 25g 188.00 466.2 5-70197 Bromo-tris-pyrrolidino- 100g 450.00 phosphoniumhexafluorophosphate [132705-51-2] C H N P BrF 12 24 3 2 6 5-70202 TATU, 98% min. 322.1 50g 243.00 5-70203 C H BF N O 100g 365.00 10 15 4 6 5-70204 TBTU, 98% min. 50g 34.00 321.1 5-70205 [125700-67-6] 100g 52.00 C H BF N O 11 16 4 5 5-41004 TDBTU 25g 251.64 349.1 5-41005 2-(3,4-Dihydro-4-oxo-1,2,3- 100g 602.35 benzotriazin-3-yl)-N,N,N',N'- tetramethyluronium tetrafluoroborate [125700-69-8] C H BF N O 12 16 4 5 2 ASK FOR OTHER QUANTITIES 9