Epilepsy Research, 12 (1992) 273-274 0920-1211/92/$05.00 © 1992 Elsevier Science Publishers B.V. All rights reserved Contents of Volume 12 (1992) Number 1 — June 1992 Research Reports Infusion of bicuculline methiodide into the tectum: model specificity of pro- and anticonvulsant actions X. Weng and H.C. Rosenberg (USA) Biological profile of the metabolites and potential metabolites of the anticonvulsant remacemide G.C. Palmer, R.J. Murray, T.C.M. Wilson, M.S. Eisman, R.K. Ray, R.C. Griffith, J.J. Napier, M. Fedorchuk, M.L. Stagnitto and G.E. Garske (USA) Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex S. Suzuki, K. Kawakami, S. Nishimura, Y. Watanabe, K. Yagi, M. Seino and K. Miyamoto (Japan) Comparative anticonvulsant potency and pharmacokinetics of (+ )- and (—)-enantiomers of stiripentol D.D. Shen, R.H. Levy, J.L. Savitch, A.V. Boddy, F. Tombret and F. Lepage (USA, UK, France) Differential effects of naloxone on postictal depression L. VeliSek and P. Mares (Czechoslovakia) Interictal depression in epilepsy A. Indaco, P.B. Carrieri, C. Nappi, S. Gentile and S. Striano (Italy) Rapid and reliable induction of partial status epilepticus in naive rats by low-frequency (3-Hz) stimulation of the amygdala D.P. Cain, D.J. McKitrick and F. Boon (Canada) Nociceptive threshold in patients with epilepsy R. Guieu, E. Mesdjian, J. Roger, P. Dano, J. Pouget and G. Serratrice (France) Number 2 — July 1992 Special Issue Neurochemical and Neuropharmacological Aspects of Epilepsy edited by P.P. De Deyn, R.A. Gross, R. D’Hooge and B.S. Meldrum Foreword P.P. De Deyn History of Epilepsy and Its Treatment A brief history of epilepsy and its therapy in the western hemisphere R.A. Gross (USA) Models of Epilepsy Genetic models of absence epilepsy, with emphasis on the WAG/Rij strain of rats A.M.L. Coenen, W.H.I.M. Drinkenburg. M. Inoue and E.L.J.M. van Luijtelaar (Netherlands) Chemical models of epilepsy with some reference to their applicability in the development of anticonvulsants P.P. De Deyn, R. D’Hooge, B. Marescau and Y.-Q. Pei (Belgium) Properties of the convulsive threshold determined by direct cortical stimulation in rats R.A. Voskuyl, A. Hoogerkamp and M. Danhof (Netherlands) PET and SPECT Findings in Epilepsy Regional brain glucose metabolism in patients with complex partial seizures investigated by intracranial EEG B. Sadzot, R.M.C. Debets, P. Maquet, C.W.M. van Veelen, E. Salmon, W. van Emde Boas, D.N. Velis, A.C. van Huffelen and G. Franck (Belgium, Netherlands) ; Single photon emission computed tomography using perfusion tracers in seizure disorders R.A. Dierckx, J. Vandevivere, L.D om, K. Melis, G. Janssens, A.D obbeleir and P.P. De Deyn (Belgium) Neurochemical Aspects of Epilepsy Contribution of Na* ,K *-ATPase to focal epilepsy: a brief review T. Grisar, D. Guillaume and A.V. Delgado-Escueta (Belgium, USA) Polyamine metabolism in epileptic cortex J. Laschet, S. Trottier, T. Grisar and V. Leviel (Belgium, France) 274 In vitro and in vivo characterization of the NMDA receptor-linked strychnine-insensitive glycine site B.W.M.M. Peeters and P.M.L. Vanderheyden (Netherlands) The GABA, receptor complex in relation to epilepsy. Reversal of (H]TBOB inhibition: a prediction of proconvulsive properties? C.M. van Rijn, E. Willems-van Bree, R. Dirksen and J.F. Rodrigues de Miranda (Netherlands) Neuropharmacology of Epilepsy Aspects of pharmacotherapy in epilepsy H. Meinardi (Netherlands) The contribution of AMPA and NMDA receptors to graded bursting activity in the hippocampal CA1 region in an acute in vitro model of epilepsy R. Williamson and H.V. Wheal (UK) Excitatory amino acids in epilepsy and potential novel therapies B.S. Meldrum (UK) [end of special issue] Announcements Number 3 — September 1992 Research Reports Valproic acid treatment of experimental status epilepticus N.Y. Walton and D.M. Treiman (USA) Effects of antiepileptic drugs on 4-aminopyridine-induced epileptiform activity in young and adult rat hippocampus Y. Fueta and M. Avoli (Canada) Anticonvulsant profile of MDL 27,266: an orally active, broad-spectrum anticonvulsant agent H.S. White, S. Patel and B.S. Meldrum (USA, UK) Cerebrovascular responses to pentylenetetrazol: time and dose dependent effects H. Goldman, R.F. Berman, J. Hazlett and S. Murphy (USA) Neuropathological changes during generalized seizures in newborn monkeys D.G. Fujikawa, B. Séderfeldt and C.G. Wasterlain (USA, Sweden) A compound score for estimating the influence of inattention and somnolence during the intracarotid amobarbital test K. Malmgren, M. Bilting, I. Hagberg, A. Hedstrom, H. Silfvenius and J.E. Starmark (Sweden) Absence of cortical white matter changes in three patients undergoing long-term vigabatrin therapy E.J. Hammond, W.E. Ballinger Jr., L. Lu, B.J. Wilder, B.M. Uthman and S.A. Reid (USA) Announcements Author Index to Volume 12 (1992) Contents of Volume 12 (1992)