IT education, particularly at business colleges, is undergoing a transformation because of the emerging federated systems or enterprise-wide systems (ES). This follows a trend in industry, which uses complex software applications like SAP and others. This movement toward ES in industry has created major challenges for integrating ES into the classroom. Enterprise Systems Education in the 21st Century presents methods of reengineering business curricula in order to use ES solutions. It also helps ES vendors understand the higher education environment so they can support college and university programs. Enterprise Systems Education in the 21st Century acts as a platform for both educators and vendors to present solutions and experiences gained from the challenges of integrating ES into the business classroom.