Andhra University IIIV B.Tech. Biotechnology (First year) (Effective from the admitted batch of 2009-2010) Work Load Total Marks S.No CCooudrsee Title Theory Practi­ Total Univ. Sessional ~redits cals Exam. Marks L T 1 BTM-l0l English 2 1 3 70 30 2 - - 2 BTM-l02 Mathematics-I 3 3 70 30 4 - 3 BTM-l03 Mathematics-II 3 3 70 30 4 - 4 BTM-l04 Physics 3 3 70 30 4 - - 5 BTM-l05 Chemistry 3 3 70 30 4 History of Science'" - - 2 6 BTM-l06 3 3 70 30 Technoloav - 4 7 BTM-l07 CPNM­ 3 3 70 30 Engineering - 5 8 BTM-l08 2 4 6 70 30 Graphics - - 2 9 BTM-l09 Physics Laboratory 3 3 50 50 Chemistry - - 2 10 BTM-110 3 3 50 50 Laboratory ,. t - - 2 11 BTM-!l1 Workshop Practice 3 3 50 50 Programming - - 2 12 BTM-112 3 3 50 50 Laboratory Total: 22 17 39 760 440 37 CPNM: Computer Programming and Numerical Methods II/IV B.Tech. Biotechnology (First semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks Course Theory S.No Title Practi Uniy. Sessional Code Total Credits -cals Exam. Marks L T - 1 BTM-211 Mathematics ­ III 3 1 4 70 30 4 Fundamentals of - - 4 2 BTM-212 5 5 70 30 BioloQY Inorganic and - 4 3 BTM-213 3 1 4 70 30 Physical Chemistry - - 4 BTM-214 Organic Chemistry 4 4 70 30 4 - - 5 BTM-215 MicrobioloaY 4 4 70 30 4 .Iaslc Electrical. 4 - 6 BTM-216 Electronics 3 1 4 70 30 Engineering Chemistry 2 - - 7 BTM-217 Laboratory-II 3 3 50 50 I{Organic Chemistry) Micro Biology - - 2 8 BTM-218 3 3 50 50 Laboratorv Total: 22 3 6 31 520 280 28 1 II/IV B.Tech. Biotechnology (Second semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks S.No Course Title Theory Practl Uniy. Sessional Code Total ~redits -cals Exam. Marks L T - 1 BTM-221 Bio Chemistry 3 1 4 70 30 4 - 2 BTM-222 Genetics 3 1 4 70 30 4 Process - 4 3 BTM-223 3 1 4 70 30 Calculations - Bio Analytical 4 4 BTM-224 3 1 4 70 30 TechniQues Fluld~nics• - 4 5 BTM-225 4 1 5 70 30 Heat Transfer Environmental - - 3 6 B1M-226 3 3 70 30 Studies Blo Chemistry • 2 Blo Analytical - - ) 7 BTM-227 3 3 50 50 Techniques Laboratory Fluid Mechanics - - 2 8 BTM-228 3 3 50 50 Laboratorv Total: 19 5 6 30 520 280 27 2 III/IV B.Tech. Biotechnology (First semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks S.No Course Title Theory Pract­ Univ. Sessional Code Total Credits leaIs Exam. Marks L T - 1 BTM-311 ThermodvnamiCs 3 1 4 70 30 4 - - 2 BTM-312 ImmunoloGv 4 4 70 30 4 - 3 BTM-313 Mass Transfer 3 1 4 70 30 4 Cell and Molecular - 4 4 BTM-314 4 4 70 30 Biology - - 5 BTM-315 Elective-I 4 4 70 30 4 - - 6 FE-Ol Free Elective-I 4 4 70 30 4 - - 7 BTM-316 Unit Operations Lab 3 3 50 50 2 Cell and Molecular - - 8 BTM-317 Biology Laboratory 3 3 50 50 2 - - 9 BTM-318 Soft Skills 3 3 50 1 Total: 22 2 9 33 520 330 29 Electlve-I 1. Energy Engineering Free Elective (FE-Qll :2. Food Technology 1. Basic Biotechnology 3. Process Optimization :2. Biosensors and 4. Systems Biology Bioelectronics III/IV B.Tech. Biotechnology (Second Semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks S.No Course Title Theory Pract­ Univ. Sessional Code Total ~redits leals Exam. Marks L T - 1 BTM-321 Biostatistics 3 1 4 70 30 4 Chemical Reaction - 4 2 BTM-322 3 1 4 70 30 EnGineerinG Bioprocess - 4 3 BTM-323 3 1 4 70 30 Engineering Down Stream - 4 4 BTM-324 3 1­ 4 70 30 Processing Environmental - 4 5 BTM-325 3 1 4 70 30 BiotechnolOGY - - 6 BTM-326 Elective-II 4 4 70 30 4. Down Stream 2 I - - 7 BTM-327 Processing 3 3 50 50 Laboratorv Bioprocess and - - 2 8 BTM-328 Reaction Engg. 3 3 50 50 Laboratory Total: 20 4 6 30 520 280 28 Elective II 1. Pharmaceutical Biotechnology . :2. Cancer Biology 3. Animal cell culture and Hybrldoma technology , 4. Stem cells In Health care "Summer Industrial Tralnlna Is compulsory at the end of III year second semester and assessment will be carried out at the end of IV year first semester. 3 IV/IV B.Tech. Biotechnology (First semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks S.No Course Title Theory Pract­ Univ. Sessional Code Total Credits icals Exam. Marks L T Enzyme Engineering - 4 1 BTM-411 3 1 4 70 30 - 2 BTM-412 Bioinformatics 3 1 4 70 30 4 - - 3 BTM-413 Genetic Engineering 4 4 70 30 4 Process Dynamics - 4 4 BTM-414 3 1 4 70 30 and Control - Industrial Biotech - 4 5 BTM-415 4 4 70 30 Products - - 6 BTM-416 Elective ­ III 4 4 70 30 4 Bioinformatic:s - - 2 7 BTM-417 3 3 50 50 Laboratorv Process Control - - 8 BTM-418 3 3 50 50 Laboratory 2 - - - 9 BTM-419 Seminar 3 3 100 2 Industrial Training - - - - - 10 BTM-420 100 Report 2 Total: 21 3 9 33 520 480 32 Elective - III 1. Biomedical Engineering i 2. Metabolic Engineering 3. Agricultural Biotechnology 4. Industrial Management and Enterpre4neurship Development r IV/IV B.Tech. Biotechnology (Second semester) (Effective from the admitted batch of 2009-2010) Work Load Total Marks Course S.No Title Theory Pract­ Univ. Sessional Code Total ~redits icals Exam. Marks £'')\9-i11 e.e.'vl'"V..Q L T 1 BTM-421 ~Economics and D 3 1 - 4 70 30 4 BioDrocess Desian Plant Cell and Tissue - - 4 2 BTM-422 4 4 70 30 Culture ' - - 3 BTM-423 Elective ­ IV 4 4 70 30 4 - 4 FE-02 Free Elective ­ II 4 4 70 30 4 Plant Cell and Tissue - - 2 5 BTM-424 3 3 50 50 Culture Laboratorv - - 6 BTM-425 Project 6 6 50 50 8 Total: 15 1 9 25 380 220 26 Elective-IV 1. Good manufacturing practices Free Elective CFE-Q21 2. IPR and Commercialization of Biotechnology 1. Nanotechnology 3. Molecular modeling and Drug design 2. Introductory 4. Marine Biotechnology Bioinformatics 4 1 B.Tech. Biotechnology (Effective from the admitted Batch of 2009-10) 1/4 B.Tech. First year BTM-I0l English The emphasis on English Language is enormously increasing as an effective medium of communication in all sectors the World over. As a consequence of this, the acquisition of effective communication skills in English has become most important to the students to flourish in their careers. In this connection, there is a need to train the students to equip themselves with the necessary skills required for effective communication in English thereby enabling them to get a good placement immediately after the completion of their undergraduate courses. To meet the objectives of developing proficiency in English communication skills and developing Listening, Speaking, Reading and Writing (LSRW) skills, the following curriculum is designed. Theory and Practice (Language Laboratory) 1. A text with focus on Skills approacr: Intended to develop the language skills of Listening, Speaking, Reading and Writing, 2. Vocabulary: a) One - word substitutes \ b) Words often confused - Pairs of Words c) Synonyms and Antonyms d) Foreign Phrases e) Phrasal verbs derived from the following dynamic verbs: Go, Get, Run, Take, Look, Hold, Put, Stand Etc. f) Idioms and phrases 3. Grammer: a) Error analysis • Correction of errors in a given sentence, errors in the use of words, errors of indianisms, use of slang, errors in punctuation b) Concord c) Articles, prepositions and words followed by prepositions d) Tenses 4. Writing skills: 1. Precis writing 2. Note making 3. Letter writing 4. Technical Report Writing 5. Preparation of C.V and Resume writing 6. Reading comprehension 7. Memo 8. Notices/Circulars agenda and Minutes of a meeting 9. E-Mail etiquette 5 10. Essay writing Text book: In order to improve the proficiency of the student in the acquisition of the above mentioned skills, the following texts and course content is prescribed. • LEARNING ENGLISH: A Communicative Approach, Hyderabad: Orient Long man. (selected lessons) The following lessons are prescribed from the above text: i) Astronomy (1) ii) Travel and transport (3) iii) Humour (4) iv) Environment (6) v) Inspiration (7) vi) Human interest (8) Reference books: 1. 'English for Engineering Students' by Sharma, G.V.L.N., 2. 'Examine your English' by Margaret M Maison, Orient Longman 3. 'Current English for Colleges' by Krishnaswami, N. and Sriraman, T., Macmillan 4. 'Creative English for Communication' by Krishnaswami, N. and Sriraman, T., Macmillan 5. 'Effective Technical Communication' by Rizvi, M Ashraf, McGraw - Hill 6. 'English for Technical Communication' by K.R. Lakshminarayana, SCITECH 6 BTM -102 Mathematics-I Partial differentiation and its applications: Functions of two or more variables, partial derivatives, homogeneous functions- Euler's theorem, total derivative, differentiation of implicit functions, geometrical interpretation -tangent plane and normal to a surface, change of variables, Jacobians, Taylor's theorem for functions of two variables, Jacobians, Taylor's theorem for functions of two variables, errors and approximations, total differential, maxima and minima of functions two variables, Lagrange's method of undetermined multiples, differentiation under the integral sign - Leibnitz Rule, involutes and evolutes, Multiple integrals and their applications: Double integrals, change of order of integration, double integrals in polar co-ordinates, areas enclosed by plane curves, triple integrals, volume of solids, change of variables, area of a curve of a curved surface, calculation of mass, center of gravity, center of pressure, moment of inertia, product of inertia, principle axes, beta function, gamma function, relation between beta and gamma functions, error function or probability integral, Solid geometry (Vector treatment ): Equation of a plane, equations of straight line, condition for a line to lie in a plane, coplanar lines, shortest distance between two lines, interaction of three planes, equation of sphere, tangent plane to a sphere, cone, cylinder, quadric surfaces, Infinite series: Definitions - convergence, divergence and oscillation of a series, general properties, series of positive terms, comparison tests, integral test, D' Alembert' s ratio test, Raabe's test, Logarithmic test, Cauchy's Root test, alternating series- Leibnitz's rule, series of positive or negative terms, power series, convergence of exponential, logerithmic and bionomial series, uniform convergence, Weirstrass M-test, properties of uniformly onvergent series. Fourier series: Euler's formulae, conditions for a Fourier expansion, functions having points of discontinuity, change of interval, odd and even functions - expansions of odd or even periodic function, halfrange series, Parsevel formula, practical harmonic analysis, Text books: I. 'Higher Engineering Mathematics' by B.S.Grewal 2. 'Mathematics for Engineering' by Chandrica Prasad Reference books: 1. 'Higher Engineering Mathematics' by M.K.Venkatraman 2. 'Advanced Engineering Mathematics' by Erwin Kreyszig 7 BTM-I03 Matbematics-II Linear algebra: Rank of a matrix, Eigen values, Eigen vectors ofa matrix, Cayley Hamilton theorem, consistency of equations, matrix invertion, Gaussian.Elimination scheme, Cholesky factorization, Jacobi and Gauss-Seidal iterative methods for solving simultaneous equations, Eigen value solution using forward iteration, inverse itrration, Hermitian and skew Hermitian forms, unitary matrix, functions of a matrix, quadratic forms and conical forms, Differential equations of first order and its applications: Formation of differential equations, solution of a differential equation, geometrical meaning, equations of the first order and first degree, variables separable, homogeneous equations, linear equations, Bernoulli's equation, exact equations, equation reducible to exact equations, equations of the first order and higher degree, Calirut's equation, geometric applications, orthogonal trajectories, physical applications, simple electric circuits, heat flow, chemical applications, Newton's law of cooling, Linear differential equations: Higher order linear differential equations with constant coefficients, deflection of beams, simple harmonic motion, oscillatory electric circuits, Series solutions of differential equations: Frobenis method, special function as solution from series, Bessel equation, Bessel functions of first and second kind, equation reducible to Bessel's equations, Legender's equations, Legender polynomial, Rodrigues formula, generating functions, recurrence relation, orthonogolity relation for Bessel functions and Legendre polynomial, Laplace transforms: Transforms of elementary functions, properties of Laplace transforms, existence conditions, inverse transforms, transform of derivatives, transform of integrals, multiplication's by '1'- division by '1', convolution theorem, application to ordinary differential equations and simultaneous linear equations with constant coefficients, unit step function, impulse functions and periodic functions. Text books: 1. 'Theory of Matrices' by Shanti narayanan. 2. 'Higher Engineering Mathematics' by B.S. Grewal 3. 'Advanced Mathematics for Engineering students, vol. 2' by Narayana, Manieavachgon Pillay, Ramanaiah Reference books: 1. 'Higher Engineering Mathematics' by M.K.Venkataraman 2. 'Advanced Engineering Mathematics' by Erwin Kreyozig 3. 'Engineering Mathematics' by P.P. Gupta 4. 'A text book on Engineering Mathematics' by N.P.Bali 8 BTM -104 Physics Thermodynamics: Heat and work, first law of thermodynamics and its applications, reversible and irreversible processes, Camot cycle and efficiency, entropy, second law of thermodynamics, entropy and disorder, entropy and probability, third law of thermodynamics, thermography and its applications. Electromagnetism: Concept of electric field - point charge in electric field, dipole in an electric field, Gauss law, some applications, electric potential and field strength, potential due to a point charge and dipole, magnetic field - magnetic force on current, torque on current loop, hall effect, Ampere's law, B near a long wire, B for a solenoid and toroid, the Biot­ Savart's law, B for a circular current loop, Faraday's law of induction, Lenz's law, calculation of inductance, L-R circuit, energy stored in magnetic field, induced magnetic fields, displacement current, energy density in electric and magnetic fields, Poynting vectors, Maxwells equations and electromagnetic waves (both differential and integral forms), magnetic properties of materials, paramagnetism, diamagnetism, ferromagnetism, ferrites and its applications, Optics: Interference, principles of superposition, Young's experiment, coherence, interference of thin films, wedge shaped film, Newtons rings, Michelson interferometer and its applications, diffraction - single slit (qualitative and quantitative treatment), polarization, polarisation by reflection, refraction and double refraction in uniaxial crystals, Nicol prism, quarter and half wave plate, circular and elliptical polarization and detection, Lasers and fibre optics: Spontaneous and stimulated emissions, population inversions, Ruby laser, Gas laser, semiconductor laser, applications of lasers, fibre optics, optical fibre and total internal reflection, acceptance angle and cone of a fibre, fibre optics in communications, optical parts in fibre, fibre optic sensors, Ultrasonics: Production of ultrasonics by magnetostriction and piezoelectric effects, ultrasonics and diffraction pattern, applications of ultrasonics, Modern physics: The quantization of energy, photoelectric effect, De Broglie concept of matter waves, uncertainty principle, Schrodinger wave equation, application to a particle in a box, elementary concepts of Maxwell-Boltzman, Bose-Einstein's and Fermi Dirac Statistics, Fermi Dirac distribution function (no derivations), free electron theory of metals, Band theory of solids, Kronig Penny model, metals, insulators and semiconductors, ferroelectrics and their applications, super conductivity, Meisner effect, types of superconductors and applications of superconductors, nanophase materials, synthesis, characterization of nanostructured materials, properties and applications, renewable energies - solar, wind and tidal, their applications. Text books: 1. 'Engineering Physics' by R.K. Gaur and S.D. Gupta 2. 'Physics' by David Halliday and Robert Resnick - Part I and Part II 3. 'Modem Engineering Physics' by A.S. Vadudeva 4. 'University Physics' by Young and Freedman 5. 'Materials Science' by V. Rajendra and A. Marikani 6. 'Nonconventional Energy' by Ashoke V. Desai 9 BTM-I05 Chemistry Water chemistry and pollution: \ Water chemistry: Sources of water, impurities - hardness and its determination, W.H.O. Limits, boiler troubles and their removal, water softening methods - lime soda, Zeolite and ion exchange, municipal water treatment - break point chlorination, desalination of sea water -electrodialysis and reverse osmosis methods, Water pollution: Source - BOD, COD, sewage treatment -preliminary, primary, secondary and tertiary, Air pollution: Source - air pollutants - CO , SOx, NOx , hydrocarbons and particulates, acid rain, green house effect, control of air pollution (general), Solid state chemistry: Classification of solids - Types of crystals, properties, imperfections in crystals, Band theory of solids, chemistry of semiconductors - intrinsic, extrinsic, compound and defect, organic semiconductors and superconductivity, purification of solids by zone refining, single crystal growth, epitaxial growth, elementary ideas on liquid crystals, Energy sources: Thermal energy: Coal- Ranking of coal -analysis (proximate and ultimate ), calorific value and determination (Bomb calorimeter method ), COKE, manufacture, Otto Hoffmann's process, applications, Chemical energy: Electrode potential-calomel electrode, galvanic cells, primary, secondary - acid and alkaline cells, fuel cells, Nuclear Energy: Fission and fusion, power rectors, atomic pile applications. Solar Energy: Methods of utilization, thermal conversion, liquid flat-plate collector, photovoltaic conversion, solar cell - applications, Corrosion chemistry: Origin and theories of corrosion, types of corrosion, factors affecting corrosion, corrosion control methods, protective coatings, metallic coatings, chemical conversion coatings ­ phosphate, chromate, anodized, organic coating, paints, special paints, varnishes and lacquers, Fuels and Lubricants: Petroleum refming, motor fuels, petrol and diesel oil, knocking, octane number, Cetane number, synthetic petrol-Fisher -Tropsch and Bergius methods, LPG and CNG ­ applications, rocket fuels, propellants, classification, Lubricants: Classification, mechanism, properties oflubricatingoils, selection.oflubricants for engineering"applications, Polymers and plastics: Definition, types of polymerization, mechanism of addition polymerization, effect of polymer sructure on properties, plastics - thermoplastic resins and thermosetting resins, compounding of plastics, fabrication of plastics, preparation and properties ofcellulose derivatives -Vinyl resins-Nylon(6,6)- bakelites - polycarbonates -epoxy resins, reinforced plastics, conducting polymers, engineering applications ofpolymers, IO