gr S>r E’$ S>r CDFD dm{f©H$ à{VdoXZ Aà¡b2015go ‘mM© 2016 VH$ ANNUAL REPORT April 2015 to March 2016 S>r EZ E {’ §Ja{à§qQ>J Ed§ {ZXmZ Ho$ÝÐ Zm‘nëbr, h¡Xam~mX- 500 001 Centre for DNA Fingerprinting and Diagnostics Nampally, Hyderabad - 500 001 1 2 CONTENTS I Mandate 5 II From the Director’s Desk 11 III Services 1. Laboratory of DNA Fingerprinting Services 21 2. Diagnostics Division 24 3. APEDA-CDFD Centre for Basmathi DNA Analysis 33 IV Research 1. Laboratory of Bacterial Genetics 37 2. Laboratory of Cell Cycle Regulation 44 3. Laboratory of Cell Death & Cell Survival 49 4. Laboratory of Cell Signalling 54 5. Laboratory of Chromatin Biology and Epigenetics 60 6. Laboratory of Chromosome Structure & Dynamics 65 7. Laboratory of Computational Biology 67 8. Laboratory of Computational & Functional Genomics 70 9. Laboratory of Drosophila Neural Development 76 10. Laboratory of Fungal Pathogenesis 80 11. Laboratory of Genomics and Profiling Applications 86 12. Laboratory of Immunology 91 13. Laboratory of Mammalian Genetics 95 14. Laboratory of Molecular Cell Biology 98 15. Laboratory of Molecular Genetics 103 16. Laboratory of Molecular Oncology 112 17. Laboratory of Neurospora Genetics 117 18. Laboratory of Plant-Microbe Interactions 121 19. Laboratory of Transcription 126 20. Other Scientific Services / Facilities a. Laboratory Animal Facility 133 b. Bioinformatics 136 c. Instrumentation 137 V Publications 139 VI Human Resource Development 149 VII Awards and Honours 153 VIII Lectures, Meetings, Workshops and Important Events 157 IX Deputations Abroad of CDFD Personnel 165 X Faculty and Officers of CDFD 171 XI Committees of the Centre 175 XII Implementation of RTI Act, 2005 187 XIII Budget and Finance 191 XII Photo Gallery 331 3 4 A{YXoe Mandate 5 6 A{KXoe grS>rE’$S>r gmogmBQ>r Ho$ g§J‘ kmnZ VWm {Z¶‘ Ed§ {d{Z¶‘m| ‘| ~VmE JE AZwgma S>rEZE q’$JaqàqQ>J Ed§ {ZXmZ H|$Ð H$s ñWmnZm {OZ CÔoí¶m| Ho$ {bE hþB© do {ZåZ àH$ma h¢ : i. {nV¥Ëd {ddmX, Amàdmg Am¡a AñnVmbm| ‘| ZdOmV {eewAm| H$s AXbm-~Xbr O¡go ‘m‘bm| ‘| {ZOr njm| g{hV {d{dY A{^H$aUm| Ho$ {bE n¶m©á AXm¶Jr na S>rEZE àmo’$mBqbJ Am¡a Cggo g§~§{YV {díbofU H$m d¡km{ZH$ AZwg§YmZ H$aZm& ii. AnamY AÝdofU A{^H$aUm| H$mo S>rEZE q’$JaqàqQ>J Am¡a Cggo g§~§{YV {díbofU VWm gw{dYmE§ àXmZ H$aZm& iii. AnamY AÝdofU Am¡a n[adma ‘m‘bm| ‘| S>rEZE àmo’$mBb {díbofU Am¡a Cggo g§~§{YV VH$ZrH$m| Ho$ gmú¶ g§~§Yr ‘yë¶ H$mo g‘PZo ‘| nw{bg H${‘©¶m|, ݶm{¶H$ d¡km{ZH$m|, dH$sbm| VWm ݶm¶nm{bH$m H$s ghm¶Vm H$aZm& iv. AmZwd§{eH$ Aì¶dñWmAm| H$mo g§gy{MV H$aZo hoVw S>rEZE Z¡Xm{ZH$ {d{Y¶m§ {gÕ H$aZm Am¡a Bg àH$ma Ho$ g§gyMZ Ho$ {bE g§narjmE§ {dH${gV H$aZm& v. nmXn Am¡a O§Vw H$mo{eH$m ‘mb, H$mo{eH$m bmBZm| Ho$ à‘mUrH$aU Ho$ {bE S>rEZE q’$JaqàqQ>J VH$ZrH$m| H$m Cn¶moJ H$aZm Am¡a Eogo à¶moOZm| Ho$ {bE Amdí¶H$VmZwgma ZB© g§narjmE§ {dH${gV H$aZm& vi. S>rEZE q’$JaqàqQ>J VH$ZrH$m| na à{ejU àXmZ H$aZm& vii. ‘yb^yV, AZwà¶wº$ AZwg§YmZ Ed§ {dH$mg H$m¶© H$aZm& viii. Xoe ‘| {M{H$Ëgm g§ñWmAm|, OZ-ñdmñ϶ A{^H$aUm| Am¡a CÚmoJ H$mo nam‘eu godmE§ àXmZ H$aZm& ix. H|$Ð Ho$ CÔoí¶m| go g§JV joÌm| ‘| {dXoer AZwg§YmZ g§ñWmAm| Ed§ à¶moJembmAm| Am¡a Aݶ A§Vaamï´>r¶ g§JR>Zm| Ho$ gmW gh¶moJ H$aZm& x. AZwg§YmZ N>mÌm| H$mo ñZmVH$moÎma Cnm{Y¶m| Ho$ {bE n§OrH¥$V H$a gH$Zo Ho$ à¶moOZ hoVw CƒVa A{YJ‘ Ho$ ‘mݶVm àmá {díd{dÚmb¶m| Ed§ g§ñWmAm| Ho$ gmW g§~§Y ñWm{nV H$aZm& xi. ^maV gaH$ma, amÁ¶ gaH$mam|, Xoe ‘| pñWV nyd© g§ñWmAm| / ݶmgm|, ì¶{º$¶m| Am¡a Aݶ J{V{d{Y¶m| Ho$ {bE A§Vaamï´>r¶ g§JR>Zm| g{hV {dXoer òmoVm| go Am{W©H$ ghm¶Vm àmá H$aZm& xii. H|$Ð gaH$ma Ho$ nyd© AZw‘moXZ go à{ejU H$m¶©H«$‘m|, d¡km{ZH$ AZwg§YmZ Am¡a Aݶ J{V{d{Y¶m| Ho$ {bE A§Vaamï´>r¶ g§JR>Zm| g{hV {dXoer òmoVm| go Am{W©H$ ghm¶Vm àmá H$aZm& xiii. H|$Ð H$s J{V{d{Y¶m| H$mo MbmZo Ho$ {bE O¡gm Amdí¶H$ ¶m gw{dYmOZH$ hmo, H$moB© ^r g§n{Îm Mb ¶m AMb ¶m ^dZm| Ed§ {Z‘m©Um| H$mo {Z{‘©V H$aZo, gwYma H$aZo, n[ad{V©V H$aZo, {Jam XoZo ¶m ‘aå‘V H$aZo hoVw Cnhma, H«$¶, {d{Z¶‘, nÅ>m, ^mS>o na boZo ×mam ¶m AݶWm {H$gr ^r Vah A{O©V H$aZm& xiv. H|$Ð Ho$ à¶moOZ hoVw, ^maV gaH$ma Am¡a Aݶ àmoZmoQ>m|, {d{Z¶‘ nÌm| ¶m Aݶ naH«$må¶ {bIVm| H$mo Amh[aV H$aZm Am¡a ñdrH$ma H$aZm, V¡¶ma H$aZm Am¡a n¥ð>m§{H$V H$aZm, ~Å>m H$aZm Am¡a naH«$m‘U H$aZm& xv. H|$Ð H$mo gm¢nr JB© {Z{Y¶m| ¶m YZ H$mo {Zdoe H$aZo Ho$ {bE, Eogr à{V^y{V¶m| H$mo ImobZo ¶m Eogo VarHo$ go, Omo {H$ g‘¶-g‘¶ na emgr n[afX ×mam {ZYm©[aV {H$E OmVo h¢, Bg àH$ma Ho$ {Zdoe H$mo {dH«$¶ ¶m njm§VaU H$aZm& 77 xvi. Cº$ g^r CÔoí¶m| ¶m CZ‘| go {H$gr CÔoí¶ H$s àm{á Ho$ {bE g^r Eogo Aݶ {d{Ygå‘V H$m¶©, O¡gm Amdí¶H$, àmg§{JH$ ¶m ghm¶H$ hmo, H$aZm& xvii. H|$Ð Ho$ CÔoí¶m| H$mo dmñV{dH$ ~ZmZo Ho$ {bE àmo’o$gam|, Aݶ g§H$m¶ nXm|, Aä¶mJV AܶoVmd¥{Îm¶m| g{hV AܶoVmd¥{Îm¶m|, AZwg§YmZ Ed§ g§dJ© nXm|, N>mÌd¥{Îm¶m|§ Am{X H$mo g§ñWm{nV H$aZm& xviii. H|$Ð Ho$ d¡km{ZH$ Ed§ àm¡Úmo{JH$s¶ H$m¶© Ho$ {bE à¶moJemmbmAm|, H$m¶©embmAm|, ^§S>ma, nwñVH$mb¶, H$m¶m©b¶ Am¡a Aݶ gw{dYmAm| H$mo ñWm{nV H$aZm& xix. VH$ZrH$s OmZH$mar H$mo CÚ‘H$Vm©Am| Am¡a CÚmoJm| go àmá ¶m CZH$mo A§VaU H$aZm, Am¡a xx. noQ>|Q>m|, {S>OmBZm| Ed§ VH$ZrH$s OmZH$mar Omo {H$ H|$Ð ×mam {dH${gV H$s JB© hmo, H$mo n§OrH¥$V H$aZm Am¡a H|$Ð Ho$ {hV ‘| Eogo noQ>|Q>m| / {S>OmBZm| / VH$ZrH$s OmZH$mar Ho$ {H$gr ^mJ H$mo A§VaU H$aZm& 88