Author index Volume 12 Abe,A. 333 Cope,B.K. 7il Harding,C.V. 675 Lamba,O.P. 279 Agata,K. 583 Crawford,K.M. 303 Harocopos,G.J. 759 Lambert,R.W. 539 Ahmed,A.R. 741 Crosson,C.E. 641 Harry,G.J. 439 Lam,K.-W. 9 Aimard,L. 885 Cullen,A.P. 97 Hartzer,M. 397 Landini,G. 23,957 Ajersch,P. 765 Cunnick,J. 373 Hayden,B.J. 239 Lass,J.H. 603 Akiba,J. 951 Curcio,A.J. 1067 Heinzmann,C. 1019 Lazarus,H.M. 603 Akova,Y.A. 1093 Cutarelli,P.E. 603 Hess,J.F. 77 Lee,V.H.L. 1041 Alcala,J. 191 Czarnecki,M. 279 Hess,J.L. 213 Lee,W.R. 143 Amoaku,W.M.K. 1009 Hill,J.M. 461,469 Leibach,F.H. 29 Amos,J.F. 313 Darjatmoko,S.R. 945 Hines,J. 521 Leibach,J.W. 29 Anand,R. 347 David,L.L. 341 Hjelmeland,L.M. 993 Liebe,S. 871 Anderson,P.J. 1 Davison,P.F. 107 Hobden,J.A. 461,469 Li,H. 89 Anderson,R.E. 851,981 Daxer,A. 1103 Hodos,W. 219,479 Li,L. 841 Aotaki-Keen,A.E. 993 Day,N.S. 981 Holden,B.A. 1001 Lin,L.-R. 397 Archer,D.B. 1009 de Coo,F.A.M. 293 Holst,A. 359 Liu,C.-Y. 963 Azuma,M. 341 de Smet,M.D. 197 Hong,B.-S. 9 Liu,J.H.K. 975 Azzarolo,A.M. 795 Del Monte,M.A. 29 Horwitz,B. 313 Liversidge,J. 923 Delaney Soldevilla,J. 133 Horwitz,J. 433 Lou,M.F. 433 Baber,W.B. 907 Devamanoharan,P.S. 55 Houston,L.L. 45 Lumsden,L. 923 Bagchi,M. 675 Dickson,D.H. 37,61 Howes,J.F. 313 Lundgren,B. 359 Bain,O. 885 Dikstein,S. 247,255 Huang,Q.-L. 433 Liitjen-Drecoll,E. 753,871 Barnett,N.L. 665 Dérfler,S. 893 Huang,X.-N. 205 Barrett,D.A. 507 Dueker,D.K. 155 Humphrey,M.F. 367 MacCallum,D.K. 303 Bartlett,J.D. 313 Dutt,J. 1093 Hurst,J.S. 655 MacDonald,E. 451 Bateman,J.B. 1019 Hykin,P.G. 255 Madsen,K. 1123 Bazan,H.E.P. 655 Efron,N. 1067 Maisel,H. 191,583 Beebe,D.C. 759 Eguchi,G. 583 Inouye,S.-I.T. 803 Mano,T. 803 Bekhor,I. 323 Eichberg,J. 1111 Ishigooka,H. 993 Marshall,G.E. 143 Bhattacharya,S.S. 861 Eichhorn,M. 753 Ishii,Y. 115 Masters,B.R. 1015 Bindley,C.D. 945 Engel,L.S. 461,469 Ishikawa,H. 1049 Maus,T.L. 621 Bloemendal,H. 871 Ernst,S.A. 303 Ishikawa,S. 1049 Maves,C.A. 539 Blumenkranz,M. 397 Ethier,C.R. 765 Itoi,M. 115 Maxwell,D.P.,Jr 907 Bobrowski,W.F. 675 Iwata,K. 685 Mayeux,P.A. 907 Bode,A.M. 593 Fan,W. 403 Mayhew,E. 347 Bodor,N.S. 501 Fijisawa,K. 261 Jabbur,N. 1093 Mazaheri,A.H. 795 Bolken,S. 593 Fitzgerald,M.E.C. 219,229 Jacobs,M.R. 603 McCartney,M.D. 783 Boney,F. 155 FitzGerald,P.G. 77 Jaffe,G.J. 45 McCoy,J.R. 711 Boney,R.S. 649,827 Fitzke,F.W. 1015 Jansweijer,C. 247,255 McKillop-Smith,S. 923 Borchman,D. 279 Fleiszig,S.M.J. 1067 Jasberg,K. 451 McLaren,J.W. 621 Bost,L.M. 993 Fletcher,E.L. 1067 Jin,Y. 403 Meijer,F. 531 Brennan,N.A. 1067 Fliigel,C. 413,871 Johnson,B.D. 561 Mellon,J. 347 Brent,B.D. 907 Forrester,J.V. 923 Johnson,D.H. 385 Miggans,S.T. 783 Bron,A.J. 247,255 Foster,C.S. 741,1093 Johnson,M.A. 239 Millar,C. 609 Brown,D. 571,877 Fox,D.A. 1111 Jumblatt,J.E. 975 Mircheff,A.K. 539,795 Brubaker,R.F. 621 Frank,R.N. 693 Jung,H.H. 727 Mishima,H. 733 Bunce,G.E. 213 Freedman,K.A. 641 Mishima,H.K. 17 Burke,J.M. 1073 Fukuchi,T. 685 Kadoya,K. 341 Misson,G.P. 23,957 Kaiya,T. 685 Miyamoto,Y. 29 Caffé,A.R. 719 Gamlin,P.D.R. 219 Kao,C.W.-C. 963 Mizoguchi,T. 333 Cagampang,F.R.A. 803 Ganapathy,V. 29,69 Kao,W.W.-Y. 963 Mockovak,M.E. 181 Cai,F. 61 Gange,S.J. 945 Kasuya,M. 115 Mohandas,T. 1019 Caldwell,R.B. 285 Garcia,C.A. 1111 Katar,M. 191 Mohimen,A. 741 Callegan,M.C. 461,469 Gardiner,T.A. 1009 Katori,M. 1049 Moll,H. 163,379 Cammarata,P.R. 403 Garner,W.H. 163,379 Kaufman,P.L. 413 Monteith-McMaster,C.A. 97 Campochiaro,P.A. 521 Gaudet,S.J. 271 Kennedy,A. 693 Moriishi,M. 17 Casselman,J.T. 77 Gebhardt,B.M. 461 Kenney,M.C. 571,877 Morrison,C. 37 Cenedella,R.J. 1025 Gery,I. 833 Kim,K.-J. 1041 Munoz,B. 123 Chader,G.J. 239,271 Ghormley,N.R. 313 Kitamura,S. 17 Mura,C.V. 1081 Chakrabarti,B. 951 Glasgow,B.J. 1019 Kitaoka,T. 993 Murray,P.I. 23,957 Chan,C.-C. 197,239,833 Gomez,Y. 593 Kiuchi,Y. 181 Chandrasekher,G. 1025 Gonzalez,K. 373 Kleiman,N.J. 423 Nakamura,M. 733 Cheasty,J.E. 809 Goss,D.A. 489 Klein,J.W. 641 Nanjo,H. 333 Chen,H. 197,851 Green,E. 593 Kobayashi,S. 115 Neumann,R. 741 Chew,C.K.S. 247,255 Gregory,C.Y. 861 Kojis,T. 1019 Nickerson,J. 239 Church,R.L. 1057 Gregory,D.S. 181 Kompella,U.B. 1041 Niederkorn,J.Y. 347 Chu,Y. 367 Griffin,C.S. 913 Konstas,A.G.P. 143 Nikaido,H. 17 Chwa,M.M. 571 Grimes,P. 89 Koutz,C.A. 981 Ni,M. 239 Clark,A.F. 783 Kuenzel,W.J. 479 Nishida,T. 733 Clements,P.J.M. 861 Hammer,R.H. 501 Kumar,G.N. 501 Nishihara,T. 333 Constable,I.J. 367 Hammond,R.W. 489 Kuppner,M.C. 923 Nishinaka,T. 333 Converse,R. 963 Handa,J.T. 45 Norton,T.T. 219 Cool,D.R. 29 Harada,Y. 1049 Laibovitz,R. 313 Nussenblatt,R.B. 197,833 1133 Current Eye Research Author index O’Callaghan,R.J. 461,469 Roque,R.S. 285 Tandon,P. 439 Wang,L. 9 Ogden,T.E. 629 Rosenbaum,J.T. 205,649,827 Tan,K.O. 1001 Wang,R.-R. 163,379 Ohji,M. 703 Rose,R.C. 593 Tano,Y. 803 Wang,Y. 809 Ollinger,K. 359 Ryan,S.J. 629 Tatsumi,K. 17 Wang,Z. 213 Opbroek,A. 571,877 Taylor,A. 1081 Wanji,S. 885 Orii,H. 583 Sack,R.A. 1001 Taylor,H. 123 Ward,T. 397 Orillac,R. 907 Sakai,K. 115 Terada,T. 333 Warren,D.W. 795 Osborne,N.N. 665 Salonen,J.S. 451 Thoft,R.A. 703 Watzke,R.C. 133 Otori,T. 733 Samples,J.R. 649 Tiffany,J.M. 247,255 Wax,M.B. 507 Otori,Y. 803 Sargan,D.R. 861 Tilson,H.A. 439 Weissman,B.A. 1067 Ottlecz,A. 1111 Sawada,K. 583 Torres-Zamorano,V. 69 Wen,Y. 323 Ozaki,Y. 279 Sawaguchi,S. 685 Trap,N.H. 293 Westerhausen-Larson,A. 963 Schlétzer-Schrehardt,U. 893 Treble,D. 9 West,S.K. 123 Padhye,N. 1081 Seery,C.M. 107 Trune,D.R. 133 Wheeldon,S.L. 593 Padilla,S. 439 Shahidullah,M. 609 Tschumper,R.C. 385 Wickstrém,K. 1123 Palmer,V. 1081 Sharir,M. 553 Tsilou,E. 271 Wilson,K. 783 Parker,C. 367 Shearer,T.R. 341 Tsui,J.Y. 675 Wilson,W.S. 609 Penn,J.S. 561 Sheedlo,H.J. 841 Turner,J.E. 841 Wu,W.M. 501 Peterson-Jones,S.M. 861 Shiels,A. 913 Petit,G. 885 Shih, Y.-F. 219,229 Udovichenko,I. 373 Xu,D. 197 Pfeilschifter,J. 727 Shimizu,K. 115 Ueno,N. 951 Pidherney,M. 347 Sidjanin,D. 773 Unakar,N.J. 675 Yamazaki,S. 803 Pineda II, R. 239 Smith,D. 1081 Urtti,A. 451 Yasunari,C. 333 Pirog,R. 765 Smith,S.B. 711 Yavarow,C.R. 593 Planck,S.R. 205 Séderpalm,A. 719 van Veen,T. 719 Ye,G.-S. 155 Pope,C. 439 Sparkes,R.S. 1019 van Haeringen,N.J. 531 Ye,J. 261,629 Potts,J.D. 759 Spector,A. 163,379,423 Varma,S.D. 55 Yorio,T. 403 Poyer,J.F. 413 Sramek,S.J. 945 Vartiainen,J. 451 Yoshitomi,T. 1049 Straatsma,B.R. 433 Vinores,S.A. 521 Yue,B.Y.J.T. 685 Raber,J.M. 833 Suh,E.D.W. 833 Vistica,B.P. 833 Reddan,J. 773 SundarRaj,N. 703 Voorter,C. 871 Zadunaisky,J.A. 261 Reinach,P. 69 Sun,T.-T. 963 Vuong,P.N. 885 Zhai,H. 489 Reiner,A. 219,229 Suzuki,N. 115 Vuorilehto,L. 451 Zhu,G. 963 Remé,C.E. 727 Suzuki,R. 1 Zigman,S. 773 Roberge,F.G. 197 Svensson,B. 359 Walkenbach,R.J. 155 Zimmerman,T.J. 553 Robertson,J.E. 205 Swarbrick,H.A. 1001 Wallow,I.H.L. 945 Zonnenberg,B.A. 293 Rodriguez,A. 1093 Szél,A. 935 Wang,F. 123 Zuckerman,R. 809 Rohlich,P. 935 Wang,G.-M. 163,379 Roh,S. 1081 Takehana,M. 115 Wang,H. 629 Rolfsen,W. 359 Takemoto,D.J. 373 Wang,J. 1057 Subject index Accommodation Calcium caffeine, AC/A ratio, convergence, accommodative convergence, calpain, hydrogen peroxide, cataract, lens, lens culture, E64 341 human 489 cataract, galactose cataract, cataract reversal, lens ion content, rat Adenylyl cyclase 675 iris/ciliary body, phorbol ester, protein kinase C, guanine nucleotide corneal endothelium, receptors, cultured cells, neurohormones, binding proteins, rabbit 507 intracellular calcium, inositol phosphates, bovine/human 303 Adhesion molecules retinal pigment epithelium (RPE), membrane transport and inflammation, sympathetic opthalmitis, human 923 permeability, apical membrane vesicles, sodium—calcium exchanger, integrins, uveitis, endotoxin, iritis, interleukin-1, rabbit 827 fluorescent probes, bovine, dogfish 261 Adrenergic nerves selenite, lens, membrane transport and permeability, Ca-ATPase 213 diabetes, choroid, iris, streptozotocin, rat 89 Calpain Age hydrogen peroxide, calcium, cataract, lens, lens culture, E64 341 lamina cribrosa, retina, optic nerve, proteoglycan, electron Cataract microscopy, human 685 calcium, galactose cataract, cataract reversal, lens ion content, rat 675 Aging calpain, hydrogen peroxide, calcium, lens, lens culture, E64 341 lens, cataract, crystallins, isoelectric focusing, calorie restriction, life glutathione-S-transferase, lens epithelium, distribution, activity, extension, Emory mouse 1081 isoenzymes, human 433 retinal pigment epithelium (RPE), cytochrome oxidase, aging lens, glutathione, glutathione S-transferase, isozyme, naphthalene maculopathy, energy, human, bovine 1073 cataract, rabbit 333 retinal pigment epithelium (RPE), morphology, hexagonality, area, lens, glutathione, sodium, potassium, rat 115 density, fovea, human 133 lens, progression, epidemiology, lens opacities, human 123 Aldose reductase lens, ultraviolet irradiation, UVB, rainbow trout 97 lens, hexokinase, sorbitol, aldose reductase mRNA, sorbitol lens epithelium, oxidative damage, DNA, human 423 dehydrogenase mRNA, hexokinase mRNA, mouse/rat 323 oxidative damage, lens, hydrogen peroxide, glutathione peroxidase protein kinase C, Tolrestat, lens epithelium, galactosemia, lens, bovine 373 mimics, riboflavin, rat 163 Alpha crystallin phacoemulsification, oxidative damage, free radicals, in vitro, lens, protein binding, urea membrane, native membrane, rat, bovine hyaluronan, rabbit 359 1025 Choroid Animal models diabetes, adrenergic nerves, iris, streptozotocin, rat 89 onchocerciasis, filaria, ocular lesions, murid, Monanema 885 Cicatricia! pemphigoid Anterior segment conjunctiva, cornea, COLO/SCaBER tumor cell lines, autoantigen, anti- lens crystallins, a6-crystallin, immunocytochemistry, primate, bovine basement membrane zone antibody, immunoblot technique, human 741 871 Ciliary body Antibiotics growth factors, ciliary epithelium, immunohistochemistry, immunogold toxicology, retina, gentamicin, aminoglycosides, retinal toxicity, labeling 893 endopthalmitis, pig 521 prorenin, immunostaining, electron microscopy, human 945 Antimicrobial agents Ciliary epithelium corneal epithelium, toxicity, gram-positive pathogens, bacterial keratitis endothelin, immunohistochemistry, human 753 603 Ciliary muscle Antimicrobials outflow facility, contractility, cholinergic agonists, aging, Macaca wound healing, cornea, epithelial migration, adverse effects, rabbit 733 mulatta 413 Aqueous humor Circadian rhythm fluorophotometry, blood-aqueous barrier, aqueous flow, aqueous flare, iris-ciliary body, neuropeptide Y, circadian rhythm, enzyme precision, circadian rhythm, human eye 621 immunoassay, rat 803 intraocular pressure, aqueous humor formation, vascular perfusion, prostaglandin, intraocular pressure, aqueous humor dynamics, timolol, bovine eye 609 sulprostone, norepinephrine, sympathetic nerve, rabbit 975 Aqueous humor dynamics Collagen glaucoma, outflow facility, ocular perfusion, bioengineering, human fibronectin, cornea, wound healing, growth factors, transforming eyes 765 growth factor 8 (TGF8), epidermal growth factor (EGF) corneal intraocular pressure, melatonin, circadian, rabbit 181 stromal fibroblasts 703 prostaglandin, intraocular pressure, circadian rhythm, sulprostone, sclera, immunogold, electron microscopy, immunohistochemistry, norepinephrine, sympathetic nerve, rabbit 975 human 143 Arachidonic acid vitreous, aging, cross-links, electrophoresis, bovine, human 951 docosahexaenoic acid, retina, lipid metabolism, fatty acids, frog 851 vitreous, beaded fibrils, fibrils, gel, bovine 107 Ascorbic acid Conjunctiva iris-ciliary body, dehydroascorbate reductase, enzyme, redox state cicatricial pemphigoid, cornea, COLO/SCaBER tumor cell lines, regulation, bovine 593 autoantigen, anti-basement membrane zone antibody, immunoblot technique, human 741 Blood flow membrane transport and permeability, chloride secretion, ocular development, choroid, myopia, myopic retinopathy, goggles, electrophysiology, dry eye, rabbit 1041 chick 219 Conjunctivitis ocular development, choroid, ocular enlargement, corneal incisions, corticosteroids, contact lens, giant papillary conjunctivitis 313 myopia, chick 229 Contact lens Blood vessels corticosteroids, conjunctivitis, giant papillary conjunctivitis 313 retina, fractal analysis, angiogram, image analysis, human 23 Pseudomonas aeruginosa, infective keratitis, cornea, bacterial Blood-aqueous barrier adherence, pili 1067 fluorophotometry, aqueous humor, aqueous flow, aqueous flare, Cornea precision, circadian rhythm, human eye 621 antimicrobials, wound healing, epithelial migration, adverse effects, rabbit 733 Caffeine cicatricial pemphigoid, conjunctiva, COLO/SCaBER tumor cell lines, accommodation, AC/A ratio, convergence, accommodative autoantigen, anti-basement membrane zone antibody, immunoblot convergence, human 489 technique, human 741 1135 Subject index collagen, fibronectin, wound healing, growth factors, transforming Experimental autoimmune uveoretinitis (EAU) growth factor 8 (TGF§), epidermal growth factor (EGF) corneal retinal S-antigen, oral tolerance, splenectomy, immunosuppression, rat stromal fibroblasts 703 833 eicosanoids, platelet activating factor, corneal PAF precursor, Extracellular matrix arachidonic acid, corneal injury, phospholipase A, rabbit 655 retinoic acid, growth factors, retina, cell culture, acidic fibroblast herpes simplex virus, fractals, keratitis, morphology, pathogenesis 957 growth factor (aFGF), basic fibroblast growth factor (bFGF) retinal keratitis, leukopenia, Pseudomonas, rabbit 461 microvascular endothelial cells 693 Pseudomonas aeruginosa, prednisolone, ciprofloxacin, keratitis, rabbit 469 Fibronectin retina, prostaglandins, lens, iris-ciliary body, 15- ketoprostaglandin collagen, cornea, wound healing, growth factors, transforming growth 5'3-reductase, metabolism, bovine 17 factor 8 (TGF8), epidermal growth factor (EGF) corneal stromal Corneal endothelium fibroblasts 703 calcium, receptors, cultured cells, neurohormones, intracellular Fluorescein angiography calcium, inositol phosphates, bovine/human 303 retinopathy of prematurity, retina, vascular pathology, oxygen, rat 561 receptors, muscarinic, cholinoceptors, human 155 Fluorophotometry Corneal epithelium blood-aqueous barrier, aqueous humor, aqueous flow, aqueous flare, differentiation, growth factors, K12 keratin, epidermal growth factor, precision, circadian rhythm, human eye 621 development, mouse 963 Fractal analysis membrane transport and permeability, Na*-H* exchanger, 5- (N- blood vessels, retina, angiogram, image analysis, human 23 methyl-N-isobutyl), amiloride, plasma membrane vesicles, bovine 69 Fractals toxicity, antimicrobial agents, gram-positive pathogens, bacterial diabetic retinopathy, neovascularisation, diabetes mellitus, retinal keratitis 603 vessels 1103 Corticosteroids herpes simplex virus, cornea, keratitis, morphology, pathogenesis 957 contact lens, conjunctivitis, giant papillary conjunctivitis 313 Cyclodextrins pilocarpine, drug delivery, pupil diameter, rabbit 641 Gangliosides Cytochrome oxidase uveal melanoma, melanoma, metastasis, murine, liver 347 Gene mapping retinal pigment epithelium (RPE), aging, aging maculopathy, energy, human, bovine 1073 tear lipocalin, tear prealbumin, chromosome 9q34, gene cluster, human Cytoskeleton 1019 lens, beaded filament, intermediate filament, cytokeratin, cDNA Glaucoma sequencing, antibodies, mouse 77 minoxidil, wound healing, 2,4-pyridinedicarboxylate, trabeculectomy lens, beaded-filament, cytokeratin, cDNA sequencing, chick 583 failure, bleb scarring, glaucoma, surgery 553 outflow facility, aqueous humor dynamics, ocular perfusion, Developmental biology bioengineering, human eyes 765 lens, receptors, tyrosine kinase, PCR, chicken 759 trabecular meshwork, intraocular pressure, organ culture, ethacrynic acid, human 385 retina, inositol phosphates, carbachol, muscarinic receptors, pigmented Glutathione rat 439 Dexamethasone cataract, lens, sodium, potassium, rat 115 trabecular meshwork, morphometrics, glaucoma, electron microscopy, lens, cataract, glutathione S-transferase, isozyme, naphthalene cataract, cultured human cells 783 rabbit 333 Dexmedetomidine retina, oxidative damage, phospholipid hydroperoxide, glutathione drug delivery, systemic absorption, topical administration, peroxidase, cumene hydroperoxide, hydrogen peroxide, bovine 9 cardiovascular effects, rabbits 451 Glutathione-S-transferase Diabetes lens epithelium, cataract, distribution, activity, isoenzymes, human 433 adrenergic nerves, choroid, iris, streptozotocin, rat 89 Glycoproteins retina, Na* K*-ATPase, streptozotocin, Zucker diabetic fatty rats 1111 Na* K*-ATPase, membrane transport and permeability, lacrimal retinal vasculature, ionizing radiation, rat 1009 system, receptors, sex dependence, androgens, rabbit 795 Diabetic retinopathy Growth factors neovascularisation, fractal, diabetes mellitus, retinal vessels 1103 ciliary body, ciliary epithelium, immunohistochemistry, immunogold Differentiation labeling 893 corneal epithelium, growth factors, K12 keratin, epidermal growth collagen, fibronectin, cornea, wound healing, transforming growth factor, development, mouse 963 factor 8 (TGF8), epidermal growth factor (EGF) corneal stromal Docosahexaenoic acid fibroblasts 703 arachidonic acid, retina, lipid metabolism, fatty acids, frog 851 corneal epithelium, differentiation, K12 keratin, epidermal growth Drug delivery factor, development, mouse 963 cyclodextrins, pilocarpine, pupil diameter, rabbit 641 extracellular matrix, retinoic acid, retina, cell culture, acidic fibroblast dexmedetomidine, systemic absorption, topical administration, growth factor (aFGF), basic fibroblast growth factor (bFGF) retinal cardiovascular effects, rabbits 451 microvascular endothelial cells 693 soft drugs, mydriatics, corneal penetration, scopolamine, retina, retina organ culture, rd degeneration, photoreceptor proteins, anticholinergics, rabbit 501 immunocytochemistry, mouse 719 retinal pigment epithelium (RPE), acidic fibroblast growth factor Ei id (aFGF), gene expression, cell culture, human 993 cornea, platelet activating factor, corneal PAF precursor, arachidonic acid, corneal injury, phospholipase A,, rabbit 655 Herpes simplex virus fractals, cornea, keratitis, morphology, pathogenesis 957 Staphylococcus, bacteria, colony count, rabbit 907 Herpes simplex virus type-1 Endothelin T lymphocytes, keratitis, CD4* T lymphocytes, CD8* T lymphocytes, ciliary epithelium, immunohistochemistry, human 753 adoptive transfer, mouse 1093 iris muscle, iris sphincter, iris dilator, BQ-123, rabbit 1049 Hexokinase Experimental autoimmune uveitis lens, aldose reductase, sorbitol, aldose reductase mRNA, sorbitol retinal S-antigen, uveitis, rapamycin, immunosuppression 197 dehydrogenase mRNA, hexokinase mRNA, mouse/rat 323 1136 Subject index 5-HT meibomian gland, lipids, Sebumeter, Meibometer, human 247 serotonin, iris sphincter muscle, iris, rabbit 665 membrane transport + permeability, Na*/H* antiport, pH regulation, Hydrogen peroxide parasympathetic secretomotor control, electrolyte secretion, stimulus- calpain, calcium, cataract, leas, lens culture, E64 341 secretion coupling, rabbit 539 Na* K*-ATPase, membrane transport and permeability, glycoproteins, Infective keratitis receptors, sex dependence, androgens, rabbit 795 Pseudomonas aeruginosa, contact lens, cornea, bacterial adherence, tears, coating inhibitory factor, precipitating inhibitory factor, pili 1067 30-kiloDalton glycoprotein 531 Inflammation Lamina cribrosa adhesion molecules, sympathetic opthalmitis, human 923 retina, optic nerve, age, proteoglycan, electron microscopy, human retinal pigment epithelium (RPE), interleukins, interleukin-1, 685 granulocyte-macrophage colony-stimulating factor, cultured human cells Lens 205 aging, cataract, crystallins, isoelectric focusing, calorie restriction, life tear film, immunoglobulin A (IgA), closed eye, complement, plasmin, extension, Emory mouse 1081 polymorphonuclear (PMN) cells, human 1001 aldose reductase, hexokinase, sorbitol, aldose reductase mRNA, Inositol phosphates sorbitol dehydrogenase mRNA, hexokinase mRNA, mouse/rat 323 developmental biology, retina, carbachol, muscarinic receptors, alpha crystallin, protein binding, urea membrane, native membrane, pigmented rat 439 rat, bovine 1025 Inositol polyphosphates calcium, selenite, membrane transport and permeability, Ca~-ATPase 213 receptors, retina, phospholipase C, vertebrates 981 calpain, hydrogen peroxide, calcium, cataract, lens culture, E64 341 Inositoltrisphosphate cataract, glutathione, glutathione S-transferase, isozyme, naphthalene retina, light, release, rat 727 cataract, rabbit 333 Integrins cataract, glutathione, sodium, potassium, rat 115 adhesion molecules, uveitis, endotoxin, iritis, interleukin-1, rabbit 827 cataract, oxidative damage, hydrogen peroxide, glutathione peroxidase Interleukins mimics, riboflavin, rat 163 retinal pigment epithelium (RPE), inflammation, interleukin-1, cataract, progression, epidemiology, lens opacities, human 123 granulocyte-macrophage colony-stimulating factor, cultured human cells cataract, ultraviolet irradiation, UVB, rainbow trout 97 205 cytoskeleton, beaded filament, intermediate filament, cytokeratin, uveitis, iritis, prostaglandins, interleukin-1, interleukin-2, cyclosporine, cDNA sequencing, antibodies, mouse 77 rabbit 649 cytoskeleton, beaded-filament, cytokeratin, cDNA sequencing, chick Intraocular pressure 583 aqueous humor, aqueous humor formation, vascular perfusion, timolol, lipids, spectroscopy, membranes, Raman spectroscopy, membrane bovine eye 609 structure, saturation, human 279 aqueous humor dynamics, melatonin, circadian, rabbit 181 major intrinsic protein (MIP), mRNA, CAT mouse 913 prostaglandin, aqueous humor dynamics, circadian rhythm, membrane transport and permeability, lens metabolism, ATP, rubidium sulprostone, norepinephrine, sympathetic nerve, rabbit 975 transport, amino acid transport, cataract, rat 55 trabecular meshwork, glaucoma, organ culture, ethacrynic acid, human myo-inositol, protein kinase C, hyperglycemic conditions, tissue 385 culture, phorbol esters, mixed micelle assay, bovine 403 Ionizing radiation NCAM, membranes, epithelium, fibers, rat, human 191 retinal vasculature, diabetes, rat 1009 receptors, tyrosine kinase, developmental biology, PCR, chicken 759 Iris retina, prostaglandins, cornea, iris-ciliary body, 15- ketoprostaglandin diabetes, adrenergic nerves, choroid, streptozotocin, rat 89 5!3-reductase, metabolism, bovine 17 Iris muscle ultraviolet irradiation, UVA, DNA single strand breaks, DNA repair, endothelin, iris sphincter, iris dilator, BQ-123, rabbit 1049 cultured lens epithelial cells, rabbit 773 Iris sphincter muscle Lens crystallins serotonin, 5-HT, iris, rabbit 665 anterior segment, a(-crystallin, immunocytochemistry, primate, bovine Iris-ciliary body 871 ascorbic acid, dehydroascorbate reductase, enzyme, redox state Lens epithelium regulation, bovine 593 cataract, oxidative damage, DNA, human 423 neuropeptide Y, circadian rhythm, enzyme immunoassay, rat 803 glutathione-S-transferase, cataract, distribution, activity, isoenzymes, retina, prostaglandins, cornea, lens, 15- ketoprostaglandin human 433 5'3-reductase, metabolism, bovine 17 transforming growth factor-a (TGFa), immunohistochemistry, rabbit, Iris/ciliary body monkey 1123 adenylyl cyclase, phorbol ester, protein kinase C, guanine nucleotide Lens protein binding proteins, rabbit 507 membrane protein, MP19, genomic DNA, gene structure, human 1057 Iritis retinoblastoma, retina, aB-crystallin, transdifferentiation, heat-shock uveitis, prostaglandins, interleukins, interleukin-1, interleukin-2, protein, human 239 cyclosporine, rabbit 649 Lid-suture myopia, ocular development, ocular occlusion, ocular enlargement, Keratitis chicks 479 cornea, leukopenia, Pseudomonas, rabbit 461 Lipids T lymphocytes, herpes simplex virus type-1, CD4* T lymphocytes, lens, spectroscopy, membranes, Raman spectroscopy, membrane CD8* T lymphocytes, adoptive transfer, mouse 1093 structure, saturation, human 279 Keratoconus meibomian gland, lacrimal system, casual levels, age and sex metalloproteinase inhibitor, cornea, TIMP-1, MMP-2, human differences, Meibometer, human 255 877 meibomian gland, lacrimal system, Sebumeter, Meibometer, human metalloproteinases, cornea, gelatinase, TIMP-1, TIMP-2, MMP-2, 247 human 571 Major intrinsic protein (MIP) Lacrimal system lens, MRNA, CAT mouse 913 meibomian gland, lipids, casual levels, age and sex differences, Meibomian gland Meibometer, human 255 lacrimal system, lipids, Sebumeter, Meibometer, human 247 Subject index lipids, lacrimal system, casual levels, age and sex differences, Outflow facility Meibometer, human 255 ciliary muscle, contractility, cholinergic agonists, aging, Macaca Melanoma mulatta 413 uveal melanoma, gangliosides, metastasis, murine, liver 347 glaucoma, aqueous humor dynamics, ocular perfusion, bioengineering, Melatonin human eyes 765 aqueous humor dynamics, intraocular pressure, circadian, rabbit 181 Oxidative damage Membrane protein cataract, lens, hydrogen peroxide, glutathione peroxidase mimics, lens protein, MP19, genomic DNA, gene structure, human 1057 riboflavin, rat 163 Membrane transport and permeability lens epithelium, cataract, DNA, human 423 calcium, selenite, lens, Ca-ATPase 213 phacoemulsification, cataract, free radicals, in vitro, hyaluronan, rabbit conjunctiva, chloride secretion, electrophysiology, dry eye, rabbit 1041 359 corneal epithelium, Na*-H* exchanger, 5-(N-methyl-N- isobutyl), retina, glutathione, phospholipid hydroperoxide, glutathione peroxidase, amiloride, plasma membrane vesicles, bovine 69 cumene hydroperoxide, hydrogen peroxide, bovine 9 lacrimal system, Na*/H* antiport, pH regulation, parasympathetic Oxygen secretomotor control, electrolyte secretion, stimulus-secretion coupling, retinal oxygenation, retina, tissue oxygen tension, oxygen consumption, rabbit 539 fluorescence quenching, oxygen maps, rats 809 lens, lens metabolism, ATP, rubidium transport, amino acid transport, cataract, rat 55 Na* K*-ATPase, lacrimal system, glycoproteins, receptors, sex Perfused eye dependence, androgens, rabbit 795 normothermic, culture, bovine eye 293 retinal pigment epithelium (RPE), calcium, apical membrane vesicles, Phacoemulsification sodium —calcium exchanger, fluorescent probes, bovine, dogfish 261 oxidative damage, cataract, free radicals, in vitro, hyaluronan, rabbit Membranes 359 lens, lipids, spectroscopy, Raman spectroscopy, membrane structure, Phosphodiesterase saturation, human 279 retina, retinal dystrophy, rcd-1 mutation, diagnostic test, progressive Metalloproteinase inhibitor retinal atrophy, dog 861 keratoconus, cornea, TIMP-1, MMP-2, human 877 Photocoagulation Metalloproteinases retinal dystrophy, photoreceptor, retinal pigment epithelium (RPE), keratoconus, cornea, gelatinase, TIMP-1, TIMP-2, MMP-2, human Royal College of Surgeons rat (RCS rat), growth factors 367 571 Photoreceptor Minoxidil retinal degeneration, retina, opsin synthesis, vitiligo, mi", mouse 711 wound healing, glaucoma, 2,4-pyridinedicarboxylate, trabeculectomy retinal dystrophy, photocoagulation, photoreceptor, Royal College of failure, bleb scarring, glaucoma, surgery 553 Surgeons rat (RCS rat), growth factors 367 Mydriatics visual pigment, retina, antibody, epitope, cones 935 soft drugs, drug delivery, corneal penetration, scopolamine, Pilocarpine anticholinergics, rabbit 501 cyclodextrins, drug delivery, pupil diameter, rabbit 641 Myeloid bodies Platelet activating factor retinal pigment epithelium (RPE), diurnal variation, chick 37 eicosanoids, cornea, corneal PAF precursor, arachidonic acid, corneal retinal pigment epithelium (RPE), retina, outer segment shedding, frog injury, phospholipase A>, rabbit 655 61 Proliferative vitreoretinopathy Myo-inositol transferrin, retinal pigment epithelium (RPE), monensin, antitransferrin lens, protein kinase C, hyperglycemic conditions, tissue culture, receptor immunotoxin, cultured RPE cells, receptors 45 phorbol esters, mixed micelle assay, bovine 403 vitreous, 5-Fluorouridine, 5-Fluorouracil, cell injection model, rabbit Myopia 397 lid-suture, ocular development, ocular occlusion, ocular enlargement, Prorenin chicks 479 ciliary body, immunostaining, electron microscopy, human 945 Prostaglandins N-acetyltransferase intraocular pressure, aqueous humor dynamics, circadian rhythm, retinal pigment epithelium (RPE), arylamine, arylalkylamine, bovine sulprostone, norepinephrine, sympathetic nerve, rabbit 975 271 retina, cornea, lens, iris-ciliary body, 15- ketoprostaglandin Na* K*-ATPase 5'3-reductase, metabolism, bovine 17 membrane transport and permeability, lacrimal system, glycoproteins, uveitis, iritis, interleukins, interleukin-1, interleukin-2, cyclosporine, receptors, sex dependence, androgens, rabbit 795 rabbit 649 NCAM Protein binding lens, membranes, epithelium, fibers, rat, human 191 lens, alpha crystallin, urea membrane, native membrane, rat, bovine Neovascularisation 1025 diabetic retinopathy, fractal, diabetes mellitus, retinal vessels 1103 Protein kinase C Neuropeptide Y aldose reductase, Tolrestat, lens epithelium, galactosemia, lens, bovine iris-ciliary body, circadian rhythm, enzyme immunoassay, rat 803 373 lens, myo-inositol, hyperglycemic conditions, tissue culture, phorbol Ocular development esters, mixed micelle assay, bovine 403 blood flow, choroid, myopia, myopic retinopathy, goggles, chick 219 Pseudomonas aeruginosa blood flow, choroid, ocular enlargement, corneal incisions, myopia, contact lens, infective keratitis, cornea, bacterial adherence, pili chick 229 1067 lid-suture, myopia, ocular occlusion, ocular enlargement, chicks 479 cornea, prednisolone, ciprofloxacin, keratitis, rabbit 469 Onchocerciasis animal models, filaria, ocular lesions, murid, Monanema 885 Optic nerve Receptors lamina cribrosa, retina, age, proteoglycan, electron microscopy, human corneal endothelium, calcium, cultured cells, neurohormones, 685 intracellular calcium, inositol phosphates, bovine/human 303 retina, confocal optical sections, three-dimensional imaging, scanning corneal endothelium, muscarinic, cholinoceptors, human 155 laser ophthalmoscope, human 1015 inositol polyphosphates, retina, phospholipase C, vertebrates 981 1138 Subject index lens, tyrosine kinase, developmental biology, PCR, chicken 759 N-acetyltransferase, arylamine, arylalkylamine, bovine 271 Na* K*-ATPase, membrane transport and permeability, lacrimal retina, Royal College of Surgeons rat (RCS rat), GFAP, Muller cells, system, receptors, sex dependence, androgens, rabbit 795 immunocytochemistry, RPE transplants, rat 841 Retina retinal dystrophy, photocoagulation, photoreceptor, Royal College of antibiotics, toxicology, gentamicin, aminoglycosides, retinal toxicity, Surgeons rat (RCS rat), growth factors 367 endopthalmitis, pig 521 taurine, taurine transport, human cell line, Na* and Cl~ dependence, arachidonic acid, docosahexaenoic acid, lipid metabolism, fatty acids, high-affinity 29 frog 851 transferrin, proliferative vitreoretinopathy, monensin, antitransferrin blood vessels, fractal analysis, angiogram, image analysis, human 23 receptor immunotoxin, cultured RPE cells, receptors 45 developmental biology, inositol phosphates, carbachol, muscarinic transplantation, retina, allotransplantation, labelled cells, rabbit 629 receptors, pigmented rat 439 Retinal S-antigen diabetes, Na* K*-ATPase, streptozotocin, Zucker diabetic fatty rats experimental autoimmune uveitis, uveitis, rapamycin, 1111 immunosuppression 197 extracellular matrix, retinoic acid, growth factors, cell culture, acidic experimental autoimmune uveoretinitis (EAU), oral tolerance, fibroblast growth factor (aFGF), basic fibroblast growth factor (bFGF) splenectomy, immunosuppression, rat 833 retinal microvascular endothelial cells 693 Retinal vasculature glutathione, oxidative damage, phospholipid hydroperoxide, glutathione diabetes, ionizing radiation, rat 1009 peroxidase, cumene hydroperoxide, hydrogen peroxide, bovine 9 Retinoblastoma growth factors, retina organ culture, rd degeneration, photoreceptor lens proteins, retina, aB-crystallin, transdifferentiation, heat-shock proteins, immunocytochemistry, mouse 719 protein, human 239 inositoltrisphosphate, light, release, rat 727 Retinoic acid lamina cribrosa, optic nerve, age, proteoglycan, electron microscopy, extracellular matrix, growth factors, retina, cell culture, acidic human 685 fibroblast growth factor (aFGF), basic fibroblast growth factor (bFGF), optic nerve, confocal optical sections, three-dimensional imaging, retinal microvascular endothelial cells 693 scanning laser ophthalmoscope, human 1015 Retinopathy of prematurity phosphodiesterase, retinal dystrophy, rcd-1 mutation, diagnostic test, fluorescein angiography, retina, vascular pathology, oxygen, rat 561 progressive retinal atrophy, dog 861 Royal College of Surgeons rat (RCS rat) photoreceptors, retinal degeneration, opsin synthesis, vitiligo, mi¥", retina, Bandeiraea (Griffonia) simplicifolia isolectin B,, Mac-la, mouse 711 phosphotyrosine, vimentin, phagocytosis, microglia 285 prostaglandins, cornea, lens, iris-ciliary body, 15- ketoprostaglandin retina, retinal pigment epithelium (RPE), GFAP, Miiller cells, 5'3-reductase, metabolism, bovine 17 immunocytochemistry, RPE transplants, rat 841 Royal College of Surgeons rat (RCS rat), Bandeiraea (Griffonia) retinal dystrophy, photocoagulation, photoreceptor, retinal pigment simplicifolia isolectin B,, Mac-la, phosphotyrosine, vimentin, epithelium (RPE), growth factors 367 phagocytosis, microglia 285 Royal College of Surgeons rat (RCS rat), retinal pigment epithelium (RPE), GFAP, Miiller cells, immunocytochemistry, RPE transplants, Sclera rat 841 collagen, immunogold, electron microscopy, immunohistochemistry, receptors, inositol polyphosphates, phospholipase C, vertebrates 981 human 143 retinal oxygenation, oxygen, tissue oxygen tension, oxygen Selenite consumption, fluorescence quenching, oxygen maps, rats 809 calcium, lens, membrane transport and permeability, Ca- ATPase 213 retinal pigment epithelium (RPE), myeloid bodies, outer segment Serotonin shedding, frog 61 5-HT, iris sphincter muscle, iris, rabbit 665 retinal pigment epithelium (RPE), transplantation, allotransplantation, Soft drugs labelled cells, rabbit 629 mydriatics, drug delivery, corneal penetration, scopolamine, retinoblastoma, lens proteins, aB-crystallin, transdifferentiation, heat- anticholinergics, rabbit 501 shock protein, human 239 Sorbitol retinopathy of prematurity, fluorescein angiography, vascular lens, aldose reductase, hexokinase, aldose reductase mRNA, sorbitol pathology, oxygen, rat 561 dehydrogenase mRNA, hexokinase mRNA, mouse/rat 323 visual pigment, photoreceptors, antibody, epitope, cones 935 Spectroscopy Retinal degeneration lens, lipids, membranes, Raman spectroscopy, membrane structure, photoreceptors, retina, opsin synthesis, vitiligo, mi’, mouse 711 saturation, human 279 Retinal dystrophy phosphodiesterase, retina, rcd-1 mutation, diagnostic test, progressive retinal atrophy, dog 861 T lymphocytes photocoagulation, photoreceptor, retinal pigment epithelium (RPE), keratitis, herpes simplex virus type-1, CD4* T lymphocytes, CD8* T Royal College of Surgeons rat (RCS rat), growth factors 367 lymphocytes, adoptive transfer, mouse 1093 Retinal oxygenation retina, oxygen, tissue oxygen tension, oxygen consumption, Taurine fluorescence quenching, oxygen maps, rats 809 retinal pigment epithelium (RPE), taurine transport, human cell line, Na®* and Cl~ dependence, high-affinity 29 Retinal pigment epithelium (RPE) aging, energy, cytochrome oxidase, aging maculopathy, energy, Tear film human, bovine 1073 inflammation, immunoglobulin A (IgA), closed eye, complement, aging, morphology, hexagonality, area, density, fovea, human 133 plasmin, polymorphonuclear (PMN) cells, human 1001 calcium, membrane transport and permeability, apical membrane Tear lipocalin vesicles, sodium—calcium exchanger, fluorescent probes, bovine, gene mapping, tear prealbumin, chromosome 9q34, gene cluster, dogfish 261 human 1019 growth factors, acidic fibroblast growth factor (aFGF), gene Tears expression, cell culture, human 993 lacrimal system, coating inhibitory factor, precipitating inhibitory inflammation, interleukins, interleukin-1, granulocyte- macrophage factor, 30-kiloDalton glycoprotein 531 colony-stimulating factor, cultured human cells 205 Toxicity myeloid bodies, diurnal variation, chick 37 corneal epithelium, antimicrobial agents, gram-positive pathogens, myeloid bodies, retina, outer segment shedding, frog 61 bacterial keratitis 603 1139 Subject index Toxicology antibiotics, retina, gentamicin, aminoglycosides, retinal toxicity, endopthalmitis, pig 521 Trabecular meshwork dexamethasone, morphometrics, glaucoma, electron microscopy, cultured human cells 783 fluoride, outflow facility, temperature, calf 1 glaucoma, intraocular pressure, organ culture, ethacrynic acid, human 385 Transferrin retinal pigment epithelium (rpe), proliferative vitreoretinopathy, monensin, antitransferrin receptor immunotoxin, cultured RPE cells, receptors 45 Transforming growth factor-a (TGFa) lens epithelium, immunohistochemistry, rabbit, monkey 1123 Transplantation retinal pigment epithelium (rpe), retina, allotransplantation, labelled cells, rabbit 629 Tyrosine kinase lens, receptors, developmental biology, PCR, chicken 759 Ultraviolet irradiation lens, cataract, UVB, rainbow trout 97 lens, UVA, DNA single strand breaks, DNA repair, cultured lens epithelial cells, rabbit 773 Uveal melanoma gangliosides, melanoma, metastasis, murine, liver 347 Uveitis adhesion molecules, integrins, endotoxin, iritis, interleukin-1, rabbit 827 iritis, prostaglandins, interleukins, interleukin-1, interleukin-2, cyclosporine, rabbit 649 retinal S-antigen, experimental autoimmune uveitis, rapamycin, immunosuppression 197 Visual pigment photoreceptors, retina, antibody, epitope, cones 935 Vitreous collagen, aging, cross-links, electrophoresis, bovine, human 951 collagen, beaded fibrils, fibrils, gel, bovine 107 proliferative vitreoretinopathy, 5-Fluorouridine, 5- Fluorouracil, cell injection model, rabbit 397 Wound healing antimicrobials, cornea, epithelial migration, adverse effects, rabbit 733 collagen, fibronectin, cornea, growth factors, transforming growth factor 8 (TGF§), epidermal growth factor (EGF) corneal stromal fibroblasts 703 minoxidil, glaucoma, 2,4-pyridinedicarboxylate, trabeculectomy failure, bleb scarring, glaucoma, surgery 553