Computers in Biology and Medicine PERGAMON www.elsevier.com/locate/compbiomed PII: S0010-4825(01)00030-0 CONTENTS OF VOLUME 31 Number 1 Samuel J. Wang, Lucila Ohno-Machado, Using patient-reportable clinical history factors to predict Hamish S. F. Fraser and R. Lee Kennedy myocardial infarction Georgia D. Tourassi, Erik D. Frederick, 15 Multifractal texture analysis of perfusion lung scans as a poten- Carey E. Floyd Jr. and R. Edward Coleman tial diagnostic tool for acute pulmonary embolism Ofer Barnea and Gabriel Gillon 27 Model-based estimation of male urethral resistance and elasticity using pressure-flow data 41 Fumikazu Miwakeichi, Ruben Ramirez- A comparison of non-linear non-parametric models for epilepsy Padron, Pedro A. Valdes-Sosa and data Tohru Ozaki Angi Qiu and Jing Bai 59 Multiple modeling in the study of interaction of hemodynamics and gas exchange Number 2 F.H.H. Al-Ghorabie, S.S.A. Natto and 73 A comparison between EGS4 and MCNP S.H.A. Al-Lyhiani computer modeling of an in vivo X-ray fluorescence system Francisco J. Sanchez- Marin 85 Automatic recognition of biological shapes using the Hotelling transform Lawrence T. Wang, Timothy D. Solberg, 101 Infrared patient positioning for stereotactic radiosurgery of Paul M. Medin and Rex Boone extracranial tumors Andrea Tura and Silvio Cavalcanti 113 Numerical simulation of flow oscillations in stenotic arterial segment Abdel-Ouahab Boudraa, Faiza Behloul, 133 Temporal covariance analysis of first-pass contrast-enhanced Marc Janier, Emmanuelle Canet, myocardial magnetic resonance images Jacques Champier, J.-P. Roux and Didier Revel Erratum Ill Contents of Volume 31 Number 3 Special issue: Goal-oriented model-based drug regimens Roger W. Jelliffe and Pascal Maire 145 Goal-oriented, model based drug regimens Dominique Breilh, Marie-Claude Saux, 147 Mixed pharmacokinetic population study and diffusion model to Pascal Maire, Jean-Maurice Vergnaud describe ciprofloxacin lung concentrations and Roger W. Jelliffe Dominique Barbolosi and Athanassios Iliadis 157 Optimizing drug regimens in cancer chemotherapy: a simulation study using a PK-PD model Daniel Claude 173 An illuminative example of nonlinear identification L. Pronzato and A. Pazman 179 Using densities of estimators to compare pharmacokinetic experiments M. Milman, F. Jiang and R. Jelliffe 197 Creating discrete joint densities from continuous ones: the mo- ment matching-maximum entropy approach Number 4 Agnes A. Dorion, Olivier Salomon, 215 Magnetic resonance imaging and cerebral volumic evaluation: Michel Zanca, Michel Duyme and comparison of four post-processing techniques Christiane Capron inan Giiler, Firat Hardalag and Serdar Miildiir 229 Determination of aorta failure with the application of FFT, AR and wavelet methods to Doppler technique Jorma Laurikkala, Martti Juhola, Seppo Analysis of the imputed female urinary incontinence data for the Lammi, Jorma Penttinen and Pauliina Aukee evaluation of expert system parameters G. Deléage, C. Combet, C. Blanchet and 259 ANTHEPROT: An integrated protein sequence analysis C. Geourjon software with client/server capabilities A. Naressi, C. Couturier, I. Castang, 269 Java-based graphical user interface for MRUI, a software R. de Beer and D. Graveron-Demilly package for quantitation of in vivo/medical magnetic resonance ' spectroscopy signals Number 5 A.B. Gumel, T.D. Loewen, P.N. Shivakumar, 287 Numerical modelling of the perturbation of HIV-1 during combi- B.M. Sahai, P. Yu and M.L. Garba nation anti-retroviral therapy M. Bernaschi and F. Castiglione 303 Design and implementation of an immune system simulator Ming-Dar Tsai, Ming-Shium Hsieh and 333 Virtual reality orthopedic surgery simulator Shyan-Bin Jou Contents of Volume 31 V E. Shalman, C. Barak, E. Dgany, 353 Pressure-based simultaneous CFR and FFR measurements: un- H. Noskowitcz, §. Einav and M. Rosenfeld derstanding the physiology of a stenosed vessel S. Hyun, C. Kleinstreuer and J.P. Archie Jr Computational particle-hemodynamics analysis and geometric reconstruction after carotid endarterectomy Markku Siermala, Martti Juhola and On preprocessing of protein sequences for neural network pre- Mauno Vihinen diction of polyproline type II secondary structures D. Benitez, P.A. Gaydecki, A. Zaidi and The use of the Hilbert transform in ECG signal analysis A.P. Fitzpatrick Number 6 C.S. Herrmann, T. Arnold, A. Visbeck, 407 Adaptive frequency decomposition of EEG with subsequent ex- H.-P. Hundemer and H.C. Hopf pert system analysis Zhong Zhang, Hiroaki Kawabata and Electroencephalogram analysis using fast wavelet transform Zhi-Qiang Liu Inan Giiler, M. Kemal Kiymik, Mehmet Akin AR spectral analysis of EEG signals by using maximum likeli- and Ahmet Alkan hood estimation Richard Cooper, Cosmin Cardan and Computer visualisation of the moving human lumbar spine Robert Allen Chuang-Chien Chiu and Shoou-Jeng Yeh Assessment of cerebral autoregulation using time-domain cross- correlation analysis Helen Hong, Stefan Grosskopf and Ventricular shape visualization using selective volume rendering M young-Hee Kim of cardiac datasets Richard M. Spencer, Jeffry D. Schroeter and Computer simulations of lung airway structures using data- Ted B. Martonen driven surface modeling techniques Inan Giiler and Serdar Miildiir A model approach to sharing electronic medical records between and within the state hospitals in Turkey Book review Announcement Contents of Volume 31 Author Index