This volume constitutes the refereed proceedings of the 24th International Workshop on Computer Science Logic, CSL 2010, held in Brno, Czech Republic, in August 2010. The 33 full papers presented together with 7 invited talks, were carefully reviewed and selected from 103 submissions. Topics covered include automated deduction and interactive theorem proving, constructive mathematics and type theory, equational logic and term rewriting, automata and games, modal and temporal logic, model checking, decision procedures, logical aspects of computational complexity, finite model theory, computational proof theory, logic programming and constraints, lambda calculus and combinatory logic, categorical logic and topological semantics, domain theory, database theory, specification, extraction and transformation of programs, logical foundations of programming paradigms, verification and program analysis, linear logic, higher-order logic, and nonmonotonic reasoning.