British Journal of Dermatology Volume 153 July-December 2005 D Published for the Blackwell British Association of Dermatologists Publishing by Blackwell Publishing British Journal of Dermatology The British Journal of Dermatology is owned by and is the official organ of the British Association of Dermatologists. EDITORS DR D.J.EEDY DR R.A.C. GRAHAM-BROWN 2005 British Association of Dermatologists Blackwell Publishing Ltd: 9600 Garsington Road, Oxford, OX4 2DQ, UK Blackwell Publishing, Inc.: Commerce Place, 350 Main Street, Malden, Massachusetts 02148-5018, USA Blackwell Publishing Asia: 550 Swanston Street, Carlton South, Victoria 3053, Australia Blackwell Verlag: Kurfiirstendamm 58, 10707 Berlin, Germany Blackwell Munksgaard: 1 Rosenorns Allé, PO Box 227, DK-1502 Copenhagen V, Denmark Blackwell Publishing Japan/Blackwell Publishing Asia, Tokyo Office: 5F, GS Chiyoda Building, 3-11-14 lidabashi, Chiyoda-ku, Tokyo 102-0072, Japan Blackwell Publishing Professional: 2121 State Avenue, Ames, IA 50014-8300, USA Contents Symptoms associated with malignancy of peripheral nerve sheath tumours: a retrospective study of 69 patients with neurofibromatosis | Volume | lumber 1, July L.VALEYRIE-ALLANORE, N.ISMAILI, S.BASTUJI-GARIN, J.ZELLER, J. WECHSLER, REVUZ AND P.WOLKENSTEIN Snippets A new endogenous retroviral sequence is expressed in skin of patients with psoriasis Research Snippets J-P.MOLES, A.TESNIERE AND J-J.GUILHOU Clinical Snippets A study of PSORSIC1 gene polymorphisms in Chinese Editorial patients with psoriasis Diagnosing erythrodermic cutaneous T-cell lymphoma Y.T.CHANG, H.N.LIU, Y.M.SHIAO, M.W.LIN, D.D.LEE, M-T.LIU, W.J.WANG S.WU, C.Y.LAI AND S.F.TSAI Epidermolysis bullosa naevi reveal a distinctive Meeting report dermoscopic pattern Summary of inaugural meeting of the Skin Care in C.M.LANSCHUETZER, M.EMBERGER, M.LAIMER, A.DIEM, J.W.BAUER, H.P.SOYER Organ Recipients Group, UK, held at the Royal Society AND H.HINTNER of Medicine, 7 October 2004 ‘Atrophic telogen effluvium’ from cytotoxic drugs and a randomized controlled trial to investigate the possible Topical review protective effect of pretreatment with a topical vitamin Fumarate hydratase mutations and predisposition to D; analogue in humans cutaneous leiomyomas, uterine leiomyomas and renal T.O.BLEIKER, N.NICOLAOU, J. TRAULSEN AND P.E.HUTCHINSON Keratinocytes cultured from patients with Hailey— cancer Hailey disease and Darier disease display distinct patterns of calcium regulation Review P.T.LEINONEN, R.M.MYLLYLA Tumour-infiltrating lymphocytes and melanoma PELTONEN, A.OIKARINEN, tumorigenesis: an insight Prognostic factors and prediction of prognosis by the CTCL Severity Index in mycosis fungoides and Sézary Original articles syndrome Cutaneous Biology C-D.KLEMKE, U.MANSMANN, N.POENI Gene expression profiling of the ageing rat vibrissa Contact Dermatitis and Allergy follicle Additive impairment of the barrier function by mechanical irritation, occlusion and sodium laury] Human mesenchymal stem cells successfully improve sulphate in vivo skin-substitute wound healing TRRCI RITE eC R.GRIESHABER, P.KLEESZ AND P.ELS CDKS regulates cell—cell and cell—matrix adhesion in Contact dermatitis to hair dyes in a Danish adult human keratinocytes population: an interview-based study H.SQSTED, U.HESSE, T.MENNE, K.E.ANDERSEN AND J.D.JOHANSED Cilomilast, tacrolimus and rapamycin modulate Novel mutations in the EDAR gene in two Pakistani dendritic cell function in the elicitation phase of consanguineous families with autosomal recessive allergic contact dermatitis hypohidrotic ectodermal dysplasia Mild recessive epidermolytic hyperkeratosis associated Epidemiology and Health Services Research with a novel keratin 10 donor splice-site mutation in a Self-reported skin morbidity and mental health. A family of Norfolk terrier dogs population survey among adults in a Norwegian city NOF F.DALGARD, A.SVENSSON, J SUNDBY AND O.S.DALGARD Clinical and Laboratory Investigations Epidemiology and morbidity of scabies and pediculosis Extracorporeal photopheresis affects interleukin (IL)-10 capitis in resource-poor communities in Brazil and IL-12 production by monocytes in patients with J.HEUKELBACH, T.WILCKE, B.WINTER AND H.FELDMEIER cl ironic graft-versus-host disease Therapeutics SOL G.POMPEI Efficacy and safety of methotrexate in recalcitrant Induction of a chemoattractive proinflammatory cutaneous lupus erythematosus: results of a cytokine response after stimulation of keratinocytes retrospective study in 43 patients NZEL, S.BRAHLER, R.BAUER, T.BIEBER AND T.TUTI with Propionibacterium acnes and coproporphyrin III A randomized placebo-controlled double-blind study BORELLI, K.JACOB, M.VOGESEI of levamisole in the treatment of limited and slowly Plaque psoriasis vs. atopic dermatitis and lichen planus: spreading vitiligo a comparison for lesional T-cell subsets, epidermal S.AGARWAL, M.RAMAM, V.K.SHARMA, S.KHANDPUR, H.PAL AND proliferation and differentiation R.M.PANDEY IV Contents 167 Systemic eight-cycle anti-CD20 monoclonal antibody Persistent acantholytic dermatosis and extensive (rituximab) therapy in primary cutaneous B-cell lentiginous ‘freckling’: a new entity?: reply from lymphomas — an applicational observation authors S.GELLRICH, J.M.MUCHE, A.WILKS, K.C.JASCH, C.VOIT, T.FISCHER, H.AUDRI S.M.COOPER ANI AND W.STERRY Ectopic hair on the glans penis M.BRAUN-FALCO AND F-M.K Concise communications Longitudinal melanonychia and pseudo-Hutchinson Genetic heterogeneity and exclusion of a modifying sign associated with amlodipine locus at 2q in a family with autosomal dominant Mi primary erythermalgia Lupus vulgaris caused by Mycobacterium bovis ssp. caprae T.M.BURNS, R.H.M.TE MORSCHE, J.B.MJ.JANSEN AND J.P.H.DRENTH First report on autochthonous urease-positive Infliximab in the management of severe pemphigus Trichophyton rubrum (T. raubitschekii) from South-east vulgaris Europe J.PARDO, P.MERCADER M.ARABATZIS, A.VELEGRAKI, T.KANTARDJIEV, V STAVRAKIEVA, D.RIGOPOULOS AND A.KATSAMBAS Methysergide-induced scleroderma-like changes of the Pegylated liposomal doxorubicin in stage IVB mycosis legs fungoides N.KLUGER ~ GIRARI D.BESSIS AN RB UILLOT G.DI LORENZO, R.DI TROLIO, M.DELFINO AND S.DE PLA Cutaneous reaction induced by vincristine Case reports Primary cutaneous B-cell lymphoma associated with Thiodiglycolic acid as a possible causative agent of actinic prurigo fixed drug eruption provoked only after continuous C.M.PERRETT, C.A-HARWOOD, M.KHORSHID, R.CERIO AND J.M.MCGREGOR administration of S-carboxymethyl-l-cysteine: case Confetti-like lesions with hyperkeratosis: a novel report and review of reported cases ultraviolet-induced hypomelanotic disorder? C.LOQUAI, D.METZE, D.NASHAN, T.A.LUGER AND M.BOHM Masked penicillin exposure leading to intensive care Cutaneous granulomas associated with primary unit treatment immunodeficiency disorders B.POLLOCK, J.GOOT, J.C.DARLID T1796A BRAF mutation is absent in Merkel cell carcinoma Dermoscopy for challenging melanoma; how to raise the ‘red flag’ when melanoma clinically looks benign ZALAUDEK, G.FERRARA, A.DI STEFANI AND G.ARGENZIANO Bullous systemic lupus erythematosus with Successful liposomal amphotericin B treatment of autoantibodies recognizing bullous pemphigoid Leishmania braziliensis cutaneous leishmaniasis antigen | M.BROWN, M.NOURSADEGHI, J.BOYLE AND R.N.DAVIDSON Undiagnosed Hailey—Hailey disease causing painful Correspondence erosive skin changes during patch testing Chemotherapeutic experience in indeterminate cell S.L.WALKER AND M.H.BECK histiocytosis Treatment with gefitinib (ZD 1839) in a patient with R.CAPUTO, A.V.MARZANO, E.PASSONI AND M.BELLINVIA advanced cutaneous squamous cell carcinoma Mycosis fungoides-associated follicular mucinosis under adalimumab S.DALLE, B.BALME, F.BERGER, S.HAYETTE AND L.THOMAS The association of naevus lipomatosus with Book reviews pilosebaceous abnormalities including fibrofolliculoma Fast facts: Eczema and Contact Dermatitis (2004) John Berth- S.J.YUN, E.J.KIM, S-J.KIM, S-C.LEE, Y.H.WON AND J-B.LEE Jones, Eunice Tan & Howard I Maibach. Health Press Nodal marginal zone lymphoma in association with ENGLISH hydroa vacciniforme-like papulovesicular eruption, Rapid Reference Dermatology (2004) David J Gawkrodger. hypersensitivity to mosquito bites and insect bite-like Elsevier Mosby reaction J.BOU T.Y.YOON, Y.G.KIM, J.W.KIM AND M.K.KIM News and Notices Successful infliximab therapy of psoriasis vulgaris and psoriatic arthritis in a patient with cirrhosis Volume 153, Number 2, August M.LEHNEN, T.FRANCKSON, J.KNAB, D.HOEFT, S.GRABBE AND J.DISSEMONI Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma and Castleman disease Snippets A.V.MARZANO, P.VEZZOLI, F.MARIOTTI, V.BONESCHI, R.CAPUTO AND E.BERTI Research Snippets Chronic urticaria responding to subcutaneous heparin Clinical Snippets sodium S.L.CHUA AND S.GIBBS Topical review Persistent acantholytic dermatosis and extensive Toxic epidermal necrolysis: current evidence, practical lentiginous ‘freckling’: a new entity? management and future directions C.GIRARD, L.DURAND, B.GUILLOT, J-J.GUILHOU AND D.BESSIS T.A.CHAVE, N.J.MORTIN Contents V Review article S.G.Y.HO, D.A.BASKETTER, D.JEFFERIES, R.J.G.RYCROFT, I.R.WHITE AND Thalidomide: dermatological indications, mechanisms J.P.MCFADDEN of action and side-effects Dermatopathology PANG, S.HSl The usefulness of clonality for the detection of cases clinically and/or histopathologically not recognized as Original articles cutaneous T-cell lymphoma Cutaneous Biology Multiple tissue kallikrein mRNA and protein expression E.ALESSI, A.COGGI, L-VENEGONI, V.MERLO AND R.GIANOTTI in normal skin and skin diseases Epidemiology and Health Services Research N.KOMATSU, K.SAIJOH, T.TOYAMA, R.OHKA The development of a preference-based measure of health in children with atopic dermatitis Role of breast tumour kinase in the in vitro K.J. STEVENS, J.E.BRAZIER, S.P.:MCKENNA, L.C.DOWARD AND M.J.CORK differentiation of HaCaT cells Photobiology Sunscreens and melanoma: the future looks bright Comparative genomic hybridization in extramammary B.L.DIFFEY Paget’s disease V-LEE, } ONG, J-H.CHOI, K-C.MOON AND J-K.KOH Therapeutics Keloid-derived fibroblasts show increased secretion of Role of antiretroviral therapies in mucocutaneous factors involved in collagen turnover and depend on manifestations in HIV-infected children over a period matrix metalloproteinase for migration of two decades E.SEOANE REULA, J.M.BELLON, D.GURBINDO AND M.A.MUNOZ-FERNANDEZ Differential expression of nitric oxide synthases in Topical pimecrolimus in the treatment of genital lichen human scalp epidermal and hair follicle pigmentary planus: a prospective case series units: implications for regulation of melanogenesis A. A.LONSDALE-ECCLES AND S.VELANGI Treatment of acne with topical antibiotics: lessons from clinical studies Clinical and Laboratory Investigations Hereditary mucoepithelial dysplasia: clinical, T. SIMONART AND M.DRAMAIX Cutaneous side-effects of transdermal iontophoresis ultrastructural and genetic study of eight patients and with and without surfactant pretreatment: a single- literature review blinded, randomized controlled trial G.L.LI, TJ.VAN STEEG, H.PUTTER, J.VAN DER SPEK, $.PAVEL, M.DANHOF AND J.A.BOUWSTRA Functional properties of the stratum corneum in patients with diabetes mellitus: similarities to senile xerosis Concise communications Enzyme-linked immunosorbent assay for detection of TOH, H.TAGAMI AND S.INOUE Circulating CD8+ lymphocytes, white blood cells, and peptide-specific human antidesmoplakin autoantibodies survival in patients with mycosis fungoides G.HINTERHUBER, M.BINDER, Y.MARQUARDT, K.CAUZA, E.RIEDI K.RAPPERSBERGER, K.WOLFF AND D.FOEDINGER SOLLI, R.CORONA Adverse cutaneous reactions to anakinra in patients Thyroid autoimmunity in chronic urticaria with rheumatoid arthritis: clinicopathological study of SWANA, P.T.SEED, A.KOB five patients A.T.VILA, L.PUIG, M.T.FERNANDEZ A systematic review of placebo-controlled randomized \.ALOMAI clinical trials of treatments used in oral lichen planus Annual incidence and mortality of bullous pemphigoid E\ IAN AND M.H.TH in the Grampian Region of North-east Scotland The double-RNA-specific adenosine deaminase V.S.GUDI, M.LWHITE, N.CRUICKSHANK, R HERRIOT, S.L.EDWARDS, F.NIMMO (DSRAD) gene in dyschromatosis symmetrica AND A.D.ORMEROD hereditaria patients: two novel mutations and one Case reports previously described The first case of cutaneous mucormycosis caused by re Rhizopus azygosporus Psoriasis in Norway as observed in a population-based \ FUJIMOTO, K.NAGAO, K.TAN MI, S-LUDAGAWA AND Norwegian twin panel M.SUGIURA OLSEN, A.GRJIBOVSKI, P.MAGNUS, K.TAMBS AND J.R.HARRIS Elastosis perforans serpiginosa-like pseudoxanthoma \ comparison between criteria for diagnosing atopic elasticum in a child with severe Moya Moya disease eczema in infants S.MEYER, L.ZANARDO, W.E.KAMINSKI, P.HORN, G.SCHMITZ HJOHNKI U.HOHENLEUTNER, W.A.HERRMANN, M.LANDTHALER AND T.VOGT KE Bullous delayed pressure urticaria: pathogenic role for Serum antidiuretic hormone is elevated in relation to eosinophilic granulocytes? the increase in average total body transepidermal water \.KERSTAN, C.ROSE, D.SIMON, H-U.SIMON, E-B.BROCKER, A. TRAUTMANN loss in severe atopic dermatitis AND M.LEVERKUS Correspondence Contact Dermatitis and Allergy Cold urticaria; disease course and outcome — an Analysis of para-phenylenediamine allergic patients in investigation of 85 patients before and after therapy relation to strength of patch test reaction Y-L.BUSS AND M.STICHERLING VI Contents 44] Docetaxel-induced recall dermatitis on previous laser Volume 153, Number 3, September treatment sites C-Y.CHU AND C-H.YAN( Snippets Cyclophosphamide—dexamethasone pulsed therapy for treatment of recalcitrant necrobiotic xanthogranuloma Research Snippets with paraproteinemia and ocular involvement Clinical Snippets EYER, R-M.SZEIMIES, M.LANDTHALER AND S.HOHENI FUTNER Editorial Successful treatment of recalcitrant acrodermatitis Recommendations in British Association of continua of Hallopeau with adalimumab and acitretin Dermatologists guidelines \.M.TOBIN AND B.KIRBY Inpatient compliance of topical applications 1.HALLAI, A.Y.FINLAY, J.GODFREY, S.KAMATH, Z.AHMED AND A.MODHA Review Rapid control of therapy-refractory pemphigus vulgaris Investigation of reactions to dental materials by treatment with the tumour necrosis factor-% inhibitor infliximab Guidelines British Association of Dermatologists guidelines for usé Long-standing remission of recalcitrant juvenile of biological interventions in psoriasis 2005 pemphigus vulgaris after adjuvant therapy with rituximab SCHMIDT, S.HERZOG, E-B.BROCKER, D.ZILLIKEN Generalized cowpox infection probably transmitted from a rat Original articles B.HONLIN Cutaneous Biology HOPFI More skin cancer detected from nonurgent referrals FK506 promotes melanocyte and melanoblast growth and creates a favourable milieu for cell migration via High local interleukin 5 production in granuloma keratinocytes: possible mechanisms of how tacrolimus faciale (eosinophilicum): role of clonally expanded ointment induces repigmentation in patients with skin-specific CD4+ cells vitiligo yAUGER, C.RONET SCHNOPF D). AABBEECC]K Caveolin-1 is expressed on multipotent cells of hair Vulval adenosis associated with toxic epidermal follicles and might be involved in their resistance to necrolysis chemotherapy 108 ;. DEBUSSCHERE Who should treat patients with primary melanoma?: reply from authors Human scalp skin and hair follicles express MCKENNA, J.C.MARIONI, R.J.LEE, R.J.PRESCOTT neurotrophin-3 and its high-affinity receptor tyrosine Who should treat patients with primary melanoma? kinase C, and show hair cycle-dependent alterations in F. THOMPSON AND |} expression The place of botulinum toxin type A in the treatment of focal hyperhidrosis Clinical and Laboratory Investigations ,ENO Silver nitrate cautery in aphthous stomatitis: a The place of botulinum toxin type A in the treatment randomized controlled trial of focal hyperhidrosis: reply from authors Nitric oxide, lipid peroxidation and antioxidant \ new type of erythrokeratoderma, or KLICK defence system in patients with active or inactive syndrome? M.PUJOL, A.ALOMAR AND J.M.DE MORAGAS Behcet’s disease A new type of erythrokeratoderma, or KLICK syndrome?: reply from authors Cytokine profiles during infliximab monotherapy in J STEENSEL, M.VAN GEEL AND P.M.STEIJLED psoriatic arthritis Evidence for a role of type I interferons in the Oo pathogenesis of dermatomyositis “EL, } LER, T.BIEBER AND T.TUTID Flow cytometric analysis of cellular infiltrate from Evidence for a role of type I interferons in the American tegumentary leishmaniasis lesions pathogenesis of dermatomyositis: reply from authors M.CAPRONI, D.TORCHIA AND P.FABBR Immunoelectron-microscopic detection of News and Notices globotriaosylceramide accumulated in the skin of Abstracts patients with Fabry disease BSPD Abstracts DA BEES Abstracts Contents Vil Fumaric acid esters for severe psoriasis: a retrospective Concise communications review of 58 cases Molecular basis of hypotrichosis with juvenile macular M.J.HARRIES, R.J.G.CHALMERS AND C.E.M.GRIFFITHS dystrophy in two siblings Decreased incidence of nonmelanoma skin cancer in M.INDELMAN, R.LEIBU, A.JAMMAL, R.BERGMAN AND E.SPRECHER patients with type 2 diabetes mellitus using insulin: a Identification of the testis-specific protein 10 (TSGA10) pilot study as serologically defined tumour-associated antigen in T-Y.CHUANG, D.A.LEWIS AND D.F.SPANDAL primary cutaneous T-cell lymphoma Autoantibody production from a thymoma and a S.M.THEINERT, M.M.PRONEST, K.PERIS, W.STERRY AND P.WALDEN follicular dendritic cell sarcoma associated with Case reports paraneoplastic pemphigus A new variant of mastocytosis: report of three cases WAD D.F.B T.LI, R.ZHENG, B.X.ZHANG, X.X.CHEN AND X,J.ZHL clinicopathologically mimicking histiocytic and T-cell receptor y gene rearrangement by multiple: vasculitic disorders polymerase chain reaction/heteroduplex analysis in K.M.DUNST, G.M.HUEMER, B.G.ZELGER AND B.ZELGER patients with cutaneous T-cell lymphoma (mycosis Onychomycosis caused by Fusarium proliferatum fungoides/Sézary syndrome) and benign inflammatory N.HATTORI, A.SHIRAI, Y.SUGIURA, W.LI, K YOKOYAMA, Y.MISAWA, disease: correlation with clinical, histological and K.OKUZUMI AND K.TAMAKI immunophenotypical findings Dementia associated with scleromyxoedema reversed R.PONTI, P.QUAGLINO, M.NOVELLI, M.T.FIERRO, A.COMESSATTI, A.PERONI by high-dose intravenous immunoglobulin BONELLO AND M.G.BERNENGO The impact of skin disease following renal B.SHERGILL, C.H-.ORTEU, S.R.MCBRIDE AND M.H.A.RUSTIN Dermoscopy is useful for the recognition of benign— transplantation on quality of life malignant compound tumours S.KEANE, P.O’KELLY, P.J.CONLON AND G.M.MURPHY Sclerosing panniculitis is associated with pulmonary P.ZABALLOS, A.LLAMBRICH, S.PUIG AND J.MALVEHY Calcifying panniculitis following subcutaneous hypertension in systemic sclerosis injections of nadroparin-calcium in a patient with jm \NO, K.YAMANE, N.YAZAWA AND K.TAMAK osteomalacia Dermatophytes can trigger cooperative (CAMP-like) A.CAMPANELLI, G.KAYA, I.MASOUYE AND L.BORRADORI haemolytic reactions P.SCHAUFUSS, J.BRASCH AND U.STELLER Gene corner Interleukin-19 upregulates keratinocyte growth factor A Japanese infant with localized ichthyosis linearis and is associated with psoriasis circumflexa on the palms and soles harbouring a LH Y-C.1LR CHEN, C-H.HSIAO, J.Y-Y.LEE, W compound heterozygous mutation in the SPINKS gene Y.MIZUNO, Y.SUGA, S.MURAMATSU, T.HASEGAWA, T.SHIMIZU AND H.OGAWA Contact Dermatitis and Allergy Correspondence Relation between patients’ and physicians’ severity A case of multiple aneurysmal fibrous histiocytomas assessment of occupational hand eczema N.ICHIKAWA, M.KOBAYASHI, M.KIMOTO, A.TANIKAWA AND M.TANAKA R.S.CVETKOVSK ENSEN, J.OLSEN, J.D.JJOHANSEN AND T.AGNER Degos disease associated with protein S deficiency Y.GILABERTE, C.COSCOJUELA, A.LEZAUN AND M.A.MARIGI Dermatological Surgery and Lasers Florid cutaneous papillomatosis leading to social A comparative study of a 595-nm with a 585-nm exclusion pulsed dye laser in refractory port wine stains B.CSETE, M.MOEZZI, ZS.LENGYEL, B.HODOSI, E.ZOMBAI AND Z.BATTYANI =Y AARRTE Chronic meningococcaemia: a forgotten meningococcal Dermatopathology disease Fibulin-5 deposition in human skin: decrease with C.A.HARWOOD, J.C.STEVENS, D.ORTON, R.C.BULL, D.PAIGE, M.P.A.LESSING ageing and ultraviolet B exposure and increase in solar P.S.MORTIMER, R.A.MARSDEN AND R.CERIO Isotretinoin-induced elkonyxis elastosis \ YUNG, P.JOHNSON AND M.J.D.GOODFIELD Topical photodynamic therapy for Bowen’s disease of the digit in epidermolysis bullosa Photobiology C.S.SOUZA, L.B.A.FELICIO, M.V.BENTLEY, A.C.TEDESCO, J.FERREIRA, C.KURACHI A randomized controlled comparison of the efficacy of AND V.S.BAGNATO Dead Sea salt balneophototherapy vs. narrowband Radiation recall dermatitis after docetaxel ultraviolet B monotherapy for chronic plaque psoriasis administration: absolute indication to replace the drug? R.S.DAWE, § 1.CAMERON, H.MOSELEY, S.H.IBBOTSON AND F.BORGIA, C.GUARNERI, F.GUARNERI AND M.VACCARO Spontaneous regression of extramammary Paget’s Therapeutics disease after excision of primary apocrine carcinoma, Anti-CD20 monoclonal antibody (rituximab) in the in an immunosuppressed patient J.C.R.BOWLING, A.POWLES, N.NASIRI, A.SEARLE AND C.B.BUNKER treatment of pemphigus J.ARIN, A.ENGERT, T.KRIEG AND N.HUNZELMANN Usefulness of CDX2 in the diagnosis of extramammary Effects and side-effects of 2% progesterone cream on Paget disease associated with malignancies of intestinal the skin of peri- and postmenopausal women: results type from a double-blind, vehicle-controlled, randomized M.C.DE NISI, A.D'AMURI, M.TOSCANO, A.V.LALINGA, L.PIRTOLI AND C.MIRACCO study Skin cancer incidence and the ageing population B.L.DIFFEY AND J.A.A.LANGTRY G.HOLZER, E.RIEGLER, HHONIGSMANN, S.FAROKHNIA AND B.SCHMIDT Vill Contents Ingestion of topical steroid triggering pustular FK506 inhibits tumour necrosis factor-& secretion psoriasis? in human keratinocytes via regulation of nuclear S.D.ORPIN, J.HAFIJI, H.M.GOODYEAR AND A.SALIM factor-KB A case of Bazex—Dupré—Christol syndrome associated -C.E.LAN, H-S.YU, C-S.WU, H-Y.KUO with multiple genital trichoepitheliomas Differential expression of melanoma-associated growth \.YUNG AND J.A.NEWTON-BISHOP factors in keratinocytes and fibroblasts by ultraviolet A Superficial granulomatous pyoderma associated with and ultraviolet B radiation chronic osteomyelitis M.BRENNER. K.DEGITZ. R.BESCH ANI E.BASSI, S.MATTHEWS AND R.CERIO Clinical and Laboratory Investigations Rare localization of low-grade fibromyxoid sarcoma to Fungiform papillary glossitis: atopic disease in the the nail region mouth? D.CABIBI, V.MUSTACCHIO, V.RODOLICO, E.BARRESI, AAMARTORANA AND S.AMATO \RKS, C.ESCARFF, L.M.YAP, V.VERLINDEN, D.JO A novel type of human papillomavirus (HPV 95): Discoid lupus erythematosus with secondary comparison with infections of closely related human amyloidosis \.M.POWELL, S.ALBERT, B.BHOGAL AN BLACK papillomavirus types K.EGAWA, R.KIMMEL AND E-M.DE VILLIERS Relative impact of CD4+CD25+ regulatory T cells and Severe recalcitrant pyoderma gangrenosum treated with tacrolimus on inhibition of T-cell proliferation in infliximab patients with atopic dermatitis M.R.KAUR AND H.M.LEWIS j AKBAF Imatinib mesilate (Glivec . ): a systemic depigmenting Efficacy of the fully human monoclonal antibody agent for extensive vitiligo? L.LEGROS, J-P.CASSUTO AND J-P.ORTONNI MOR102 (#5) against intercellular adhesion Mucous membrane pemphigoid: management of molecule | in the psoriasis—severe combined advanced ocular disease with intravenous immunodeficient mouse model H.BOEHNCKE, F.R.OCHSENDORF, S.NOLI cyclophosphamide and amniotic membrane ). WALDHERR HA RGEF transplantation The Objective Severity Assessment of Atopic Dermatitis P.D.YESUDIAN, S.ARMSTRONG, J.I.CAWOOD, R.B.A AND S.B.KAYE (OSAAD) score: validity, reliability and sensitivity in B-chronic lymphocytic leukaemia in association with adult patients with atopic dermatitis necrobiosis lipoidica-like lesions F.BENEDIX, G.METZLER, AND M.BERNI Book reviews Photosensitive Smith—Lemli—Opitz syndrome is not Theirs BH, Lang PG (eds) Year Book of Dermatology and caused by a singgl e gene mutation: analysis of the g§ ene Dermatologic Surgery 2004 Mosby encoding 7-dehydrocholesterol reductase in five U.K. N.H.COX families David Slater 2nd Edition, An illustrated guide to skin lymphoma ANS LORENZO CERRONI, KEVIN GATTER AND HELMOT KERI Dermatological Surgery & Lasers News and Notices Investigation of the use of the pulsed dye laser in the treatment of Bowen's disease using 5-aminolaevulinic Volume 153, Number 4, October acid phototherapy Dermatopathology Snippets Expression of RPE65, a putative receptor for plasma Research Snippets retinol-binding protein, in nonmelanocytic skin Editorial tumours Topical tacrolimus and pimecrolimus and the risk of G.HINTERHUBER K.WOLFF AND D cancer: how much cause for concern? \._D.ORMEROD Subcutaneous sarcoidosis—clinicopathological study of 10 cases Review article J.MARCOVAL, J.MANA Diet and psoriasis: experimental data and clinical evidence Photobiology Ultraviolet exposure patterns of Irish and Danish M.WOLTERS gardeners during work and leisure Original articles E.THIEDEN, S.M.COLLINS, P.A.PHILIPSEN, G.M.MURPHY ANI Cutaneous Biology Inhibiting the growth of malignant melanoma Therapeutics by blocking the expression of vascular endothelial Fumaric acid esters in necrobiosis lipoidica: results of a prospective noncontrolled study growth factor using an RNA interference approach \.KREUTER, C.KNIERIM, M.STUCKER J. TAO, Y-T.TU, C-Z.HUANG, A-P.FENG, Q.WU, Y-J.LIAN, L-X.ZHANG, X-P.ZHANG AND G-X.SHEN AND T.GAMBICHLER Contents IX 5 -fluorouracil Is melatonin useful in alopecia: critical appraisal of a treatment of actinic keratoses randomized trial? weekly treatment Reply to: Is melatonin useful in alopecia: critical appraisal of a randomized trial? Sign of Leser-Trelat in a heart transplant recipient Treatment for poikilodermatous erythema of miN QgWumu”n od 1 tfoolr dermatomyositis with the pulsed dye laser Sentinel node biopsy in problematic melanocytic lesions Book reviews DERMOGRAPHIES - Autobiographies in Dermatology Volume I Edited by Benjamin Barankin Publisher Community Books, Lockeport, Nova Scotia Creamer D, du Vivier A (eds). 50 cases in dermatological medicine. Taylor & Francis, 2005 News and Notices Volume 153, Number 5, November Snippets Research Snippets Clinical Snippets Topical review The potential of pharmacogenetics in optimizing the use of methotrexate for psoriasis Review article The new World Health Organization—European Organization for Research and Treatment of Cancer classification for cutaneous lymphomas: a practical marriage of two giants Original articles Cutaneous Biology Early epidermal response after a single dose of 7-rays in organotypic culture of human breast skin Differential expression of angiotensin receptors in human cutaneous wound healing Expression of haptoglobin in human keratinocytes and Langerhans cells ution regimen for multiple bone amam~m Mar—y P>a get » aisease 900 Mutant p53 melanoma cell lines respond differently to CP-31398-induced apoptosis 1 rate of abstracts presented at th f Dermatologists Annual Me{ eti Clinical and Laboratory Investigations The dynamics of gene expression of interleukin-19 and opac I yadermoperI lostiuis: impI rovemeé interleukin-20 and their receptors in psoriasis