(cid:2) (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 1 Seat No. B.Pharmacy (Semester – I) Examination, 2015 PHARMACEUTICS – I (CGPA) Day and Date : Monday, 7-12-2015 Max. Marks : 70 Time : 10.30 a.m. to 1.30 p.m. 1. Multiple choice questions. (1×15=15) 1) Third edition of IP was reconstituted under the chairmanship of a) B.N. Ghosh b) B. Mukharji c) R.N. Chopra d) Nityanand 2) One pound (Lb) = _________ ounces in Apothecaries system. a) 16 b) 12 c) 8 d) 20 3) The first edition of National Formulary of United States was published in __________ by American Pharmaceutical Association. a) 1975 b) 1868 c) 1820 d) 1858 4) The first edition of Martindale’s Extra pharmacopoeia was published in a) 1860 b) 1883 c) 1820 d) None of the above 5) Homoeopathy was proposed by physician a) Samuel Hahnemann b) Hippocrates c) Dioscorides d) None of these 6) __________ serve as a guide for research on indigenous drugs. a) IPC b) BPC c) NF d) USP 7) Following method used for formulation of emulsion a) Bottle method b) Wet gum method c) Dry gum method d) All of above P.T.O. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 1 -2- 8) ‘Principle of single remedy’, is basic principle of _________ medicines. a) Siddha b) Homoeopathy c) Unani d) None of above 9) The principles and Doctrines of _________ system have a close similarity to Ayurveda. a) Siddha b) Homoeopathy c) Unani d) None of above 10) Glycerites contains not less than __________ % weight of glycerine. a) 50 b) 60 c) 70 d) 80 11) Astanga Hridaya written by a) Acharya Charak b) Acharya sushruta c) Acharya Vagabhatta d) Hippocrates 12) _________ is branch of Ayurveda deals with treatment and diagnosis of poisoning. a) Vijikaran Tantra b) Kaumarabhritya c) Agad Tantra d) Salya 13) __________ is example of semisolid dosage form in Ayurveda. a) Lepa b) Pills c) Gutika d) Asava 14) Suspension is __________ liquid dosage forms. a) Monophasic b) Biphasic c) Both a and b d) None of the above 15) One tea spoonful ________ ml. a) 4 b) 8 c) 15 d) 30 2. Answer any five. (5×5=25) 1) Define and classify syrup and write uses of syrups. 2) Discuss unani system of medicine. 3) Give classification, advantages, disadvantages of solution. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 1 -3- 4) Give merits and demerits of injectables. 5) What is Batch manufacturing record as per GMP ? 6) Discuss briefly United State Pharmacopoeia. 3. Answer any three. (10×3=30) 1) Discuss development of Pharmaceutical industries in India. 2) Define and classify dosage form and add short note on need of dosage form. 3) Enlist all parameters of preformulation and explain any four. 4) Add short note on career in pharmacy. _______________ (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 2 Seat No. B.Pharm. (Semester – I) Examination, 2015 PHARMACEUTICAL INORGANIC CHEMISTRY (CGPA) Day and Date : Wednesday, 9-12-2015 Max. Marks : 70 Time : 10.30 a.m. to 1.30 p.m. 1. Multiple choice questions : (15×1=15) 1) According to the I.P. sparingly should be ________ volume (ml) per gram of solvent. A) 100 to 1,000 B) 1 to 10 C) 30 to 100 D) 1,000 to 10,000 2) Synonym of CuSO is 4 A) Cupric sulphate B) Cuprous sulphate C) Cupric sulphide D) Cupric sulphur 3) The chemical name as sanctioned and employed by ________ is given. A) IUPAC B) IUPCA C) IUCAP D) IPC 4) The shoulder of cylinder of O is painted with 2 A) Orange B) Gray C) White D) Black 5) Epsom salt is synonym of A) MgSO B) Na CO C) NaCl D) NaHCO 4 2 3 3 6) Potassium chloride is assayed by ______ titration. A) Argentometric titration B) Redox titration C) Precipitation D) None of above 7) Talc is purified natural A) Magnesium silicate B) TiO 2 C) Precipited chalk D) None 8) The colour of CuSO is 4 A) Pink B) Yellow C) Blue D) Gray 9) French chalk is A) Precipited chalk B) Purified talc C) Baking soda D) Sodium sulphate 10) Lead acetate absorbs A) Hydrogen sulphide B) Oxygen C) Hydrogen D) Ozone 11) The indicator used in silver nitrate assay is A) Phenolphthalein B) Methyl orange C) Methyl red D) Ferric ammonium sulphate P.T.O. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 2 -2- 12) The formula for potassium permagnate is A) K MnO B) KMnO 2 4 4 C) K SO D) MnSO 2 4 4 13) The use of zinc sulphate is A) Astrigent B) Emetic C) Laxative D) None 14) Sun burn and sun tan are caused by A) Visible region light B) Infrared light C) Ultra violet light D) Far infrared light 15) ___________ is used as saline cathartics. A) Magnesium sulphate B) Carbon dioxide C) Calcium gluconate D) None of above 2. Answer any five of the following questions : (5×5 = 25) 1) Write the principle and reaction involved in limit test for sulphate. 2) Write a note on electrolyte used in combination therapy. 3) What are antacids ? Explain in detail of sodium containing antacid. 4) Explain copper sulphate as emetics. 5) Which different aspects of drugs covered in as official monograph ? 6) Write a note on carbon dioxide used as official gas. 3. Answer any three of the following questions : (10×3 = 30) 1) Write the principle and reaction involved limit test for arsenic and draw a neat labeled diagram of Guitzeit apparatus with specifications. 2) Write assay of : 1) Al(OH) 2) KMnO 3) KCl 2 4 3) Write properties and reaction 1) Sodium nitrite 2) Ammonium chloride 4) Discuss in detail about cyanide poisoning, how will you treat cyanide poisoning ? Explain with example. ______________ (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 3 Seat No. B.Pharm. (Semester – I) (CGPA) Examination, 2015 BIOCHEMISTRY – I Day and Date : Friday, 11-12-2015 Total Marks : 70 Time : 10.30 a.m. to 1.30 p.m. 1. 1) Which of the following enzyme in glycolysis catalyses an irreversible reaction ________ (1×15=15) a) glucokinase b) phosphofructokinase c) pyruvatekinase d) all of above 2) The simultaneous transport of two different molecules in the opposite direction is called as _________ a) uniport b) symport c) antiport d) cotransport 3) The no. of ATP produced when 2 molecule of acetyl - CoA is oxidized through TCA cycle _______ a) 12 b) 24 c) 32 d) 36 4) __________ transport occurs against a concentration gradient. a) active b) passive c) facilitated d) osmotic 5) Internal chamber of mitochondria is known as _________ a) matrix b) cytosol c) mitosol d) a and b 6) The glycosaminoglycan that serves as an anticoagulant __________ a) heparin b) hyluronic acid c) chondroitin sulphate d) dermatan sulphate 7) A sugar alcohol is __________ a) mannitol b) trehalose c) xylulose d) arabinose P.T.O. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 3 -2- 8) A positive seliwinoff test is obtained with ________ a) glucose b) lactose c) fructose d) maltose 9) Rancidity of fat is prevented by addition of __________ a) Vitamin E b) Vitamin A c) Copper d) None of the above 10) Solid alcohol from bile is called as _________ a) Cholesterol b) Ergosterol c) Steroids d) Sterol 11) Oxidation of fatty acid takes place at _________ carbon. a) α b) β c) γ d) δ 12) Special Carnitine transport system is required for ________ a) transport of fatty acid b) activation of fatty acid c) proper oxidation d) none of the above 13) The transport for which ATP (metabolic energy) is required ________ a) active b) passive c) facilitated d) osmotic 14) The HMP shunt produces ________ a) FMN b) NADPH c) GDP d) FAD 15) Synthesis of glycogen from glucose called ________ a) glycogenesis b) glycogenolysis c) glycolysis d) gluconeogenesis 2. Answer any five of the following questions. (5×5=25) 1) What are compound lipids ? Write down structure and function of phospholipid. 2) Explain the structure and functions of starch. 3) Write short note on fluid mosaic model of cell membrane. Write about transport systems. 4) Explain the terms Acid value, Iodine value, Saponification value. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 3 -3- 5) Draw a neat lebelled diagram of eukaryotic cell. Explain structure and function of power house of cell and lysosomes. 6) Explain the significance of phenyl hydrazine test and Fehling’s test. 3. Answer any three following questions. (3×10=30) 1) Explain in detail synthesis of cholesterol, structure and write its significance. 2) Describe the structure and functions of mucopolysaccharides. 3) Explain in detail glycogenesis and glycogenolysis. Add note on its significance. 4) Explain mechanism of β-oxidation of fatty acid. Give energetics. _________________ (cid:2) (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 4 Seat No. B.Pharmacy (Semester – I) (CGPA) Examination, 2015 ANATOMY, PHYSIOLOGY AND HEALTH EDUCATION – I Day and Date : Monday, 14-12-2015 Max. Marks : 70 Time : 10.30 a.m. to 1.30 p.m. 1. Tick mark the correct answer. (1×15=15) 1) Mature RBC survives for _________ day in the circulation. a) 2 to 4 days b) 120 days c) 11 to 14 days d) 8 to 10 days 2) Duration of ventricular systole is a) 0.8 second b) 0.1 second c) 0.3 second d) 0.4 second 3) Expired air contain a) less oxygen b) more co c) water vapour d) all of the above 2 4) Temporary storage of food at a) mouth b) oesophagus c) stomach d) intestine 5) Stroke volume × Heart rate = ? a) Cardiac output b) Stroke volume c) Cardiac reserve d) Total blood volume 6) About __________ Litre of Saliva produced daily. a) 1 Litre b) 1.5 Litre c) 2 Litre d) 2.5 Litre 7) Platelets measures _________ size. a) 2 to 4μ b) 12 to 15μ c) 10 to 12μ d) 20 to 22μ 8) ________ is the first part of small intestine. a) Duodenum b) Jejunum c) Ileum d) Caecum P.T.O. (cid:2)(cid:3)(cid:4)(cid:5)(cid:6)(cid:7)(cid:2) SLR-I – 4 -2- 9) Blood is a __________ connective tissue. a) hardest b) fibrous c) loose d) liquid 10) Special collections of lymphoid tissue constitute the a) Spleen b) Tonsils c) Payer’s patches d) All of the above 11) The ECG originates from _________ and is called as ‘sinus rhythm’. a) S.A. Node b) A.V. Node c) Bundle of His d) Perkinjefibres 12) Lymph node having only _________ efferent lymph vessel. a) four to five b) six to seven c) seven to eight d) only one 13) _________ one in each lung. a) Bronchi b) Bronchioles c) Alveoli d) Other than a, b & c 14) The normal pulse rate is about a) 60 beats/minute b) 72 beats/minute c) 80 beats/minute d) 110 beats/minute 15) Stomach starts from a) cardiac orifice b) fundus c) lesser curvature d) pyloric orifice 2. Answer any five. (5×5=25) A) Give composition and functions of saliva. B) Explain the anatomy of spleen. C) Describe erythrocytes with their functions. D) Define Ingestion, Digestion, Absorption, Defecation and Gastritis. E) Write a note on different valves in heart. F) Describe anatomy and physiology of liver.