This page intentionally left blank 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page i ATLAS OF GROSS PATHOLOGY Detailed understanding of gross pathology is mandatory for successful patholo- gists, but this knowledge also provides a sound foundation for those intending to become surgeons, internists, and obstetrician/gynecologists. Some knowledge of gross pathology is important for members of the allied health professions and dental students. For pathologists, pathology residents, and pathology assistants, knowledge of gross pathology is essential for guidance in selecting the correct areas of pathologic lesions to sample for microscopy and frozen section examina- tion. This atlas aims to provide a comprehensive illustration and description of a wide range and number of pathologic processes and diseases affecting all the major organs of the body. Emphasis is placed on how the anatomic structure of different organs may determine the pattern of involvement by disease processes and how such patterns may aid in the correct diagnosis of the gross pathology. In some cases, multiple illustrations of disease processes are given to show evolu- tion of the disease. Histologic illustrations of selected gross lesions are also included where relevant. The atlas is illustrated with more than 1,200 color pho- tographs. Dr. Alan G. Rose, MD, FRCPath, FACC, is Professor of Pathology at the University of Minnesota Medical School. He is also the Director of Autopsy Service at the University of Minnesota Medical Center, Fairview; the Residency and Fellowship Training Program; and the Medical School Pathology Teaching Program at the University of Minnesota. 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page ii 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page iii ATLAS OF GROSS PATHOLOGY with Histologic Correlation ALAN G. ROSE University of Minnesota CAMBRIDGE UNIVERSITY PRESS Cambridge, New York, Melbourne, Madrid, Cape Town, Singapore, São Paulo Cambridge University Press The Edinburgh Building, Cambridge CB2 8RU, UK Published in the United States of America by Cambridge University Press, New York www.cambridge.org Information on this title: www.cambridge.org/9780521868792 © Alan G. Rose 2008 This publication is in copyright. Subject to statutory exception and to the provision of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published in print format 2008 ISBN-13 978-0-511-43679-6 eBook (EBL) ISBN-13 978-0-521-86879-2 hardback Cambridge University Press has no responsibility for the persistence or accuracy of urls for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate. Every effort has been made in preparing this publication to provide accurate and up to date information that is in accord with accepted standards and practice at the time of publication. Nevertheless, the authors, editors, and publisher can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors, and publisher therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this publication. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use. 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page v CONTENTS 1 Cardiac Diseases page 1 2 Pulmonary Pathology 90 3 Kidneys, Ureters, and Urinary Bladder 157 4 Liver, Biliary System, and Pancreas 207 5 Salivary Glands and GIT 272 6 Female Genital Tract and Breast 358 7 Diseases of the Male Genital System 428 8 Bones and Joints 460 9 Diseases of the Spleen, Lymph 515 Nodes, and the Thymus Gland 10 Pituitary, Carotid Body, Thyroid 541 Gland, and Adrenals 11 Skin and Soft Tissues 566 12 Central Nervous System 607 Index 655 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page vi 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page vii ATLAS OF GROSS PATHOLOGY 9780521868792_FM_pi-viii.qxd 5/21/08 2:15 PM Page viii