American Journal of Physiology: Cell Physiology No. 1. JULY 1994 INVITED REVIEW Role of membrane trafficking in plasma membrane solute transport N. A. Bradbury and R. J. Bridges TGF-B-induced macrophage colony-stimulating factor gene expression in various mesenchymal cell lines T. Takaishi, T. Matsui, T. Tsukamoto, M. Ito, T. Taniguchi, M. Fukase, and K. Chihara ADH-induced recycling of fluid-phase marker from endosomes to the mucosal surface in toad bladder R. A. Coleman and J. B. Wade Adenosine transport in cultured human umbilical vein endothelial cells is reduced in diabetes L. Sobrevia, S. M. Jarvis, and D. L. Yudilevich Tyrosine kinase involvement in IL-1f8-induced expression of iNOS by B-cells purified from islets of Langerhans J. A. Corbett, G.K won, T. P. Misko, C. P. Rodi, and M. L. McDaniel Effects of tetrodotoxin-induced neural inactivation on single muscle fiber metabolic enzymes R. N. Michel, G. Cowper, M. M.-Y. Chi, J. K. Manchester, H. Falter, and O. H. Lowry ATP depletion rather than mitochondrial depolarization mediates hepatocyte killing after metabolic inhibition A.-L. Nieminen, A. K. Saylor, B. Herman, and J. J. Lemasters Osmotic and other properties of isolated human cheek epithelial cells E. J. Lee, G. S. Patten, S. L.B urnard, and E. J. McMurchie Characterization of Na*-H* antiporter activity associated with human cheek epithelial cells E. J. McMurchie, S. L. Burnard, G. S. Patten, E. J. Lee, R. A. King, and R. J. Head Mechanism of desensitization of the cloned vasopressin V,, receptor expressed in Xenopus oocytes M. H. Nathanson, A. D. Burgstahler, J. J. Orloff, A.M ani, and M. S. Moyer HSP-72 synthesis is promoted by increase in [Ca?*]; or activation of G proteins but not pH; or cAMP J. G. Kiang, F. E. Carr, M. R. Burns, and D. E. McClain Soleus muscle nascent polypeptide chain elongation slows protein synthesis rate during non-weight-bearing activity Z. Ku and D. B. Thomason Contractile economy and aerobic recovery metabolism in skeletal muscle adapted to creatine depletion T. S. Moerland and M. J. Kushmerick Picomolar doses of substance P trigger electrical responses in mast cells without degranulation J. Janiszewski, J. Bienenstock, and M. G. Blennerhassett Na* transport pathways in secretory acinar cells: membrane cross talk mediated by [Cl~]; M. A. Robertson and J. K. Foskett Epithelial Ca?*+ channels sensitive to dihydropyridines and activated by hyperpolarizing voltages H. Matsunaga, B. A. Stanton, F. A. Gesek, and P. A. Friedman Permeabilization of MDCK cells with cholesterol binding agents: dependence on substratum and confluency A. Esparis-Ogando, C. Zurzolo, and E. Rodriguez-Boulan Cell fatty acid composition affects free radical formation during lipid peroxidation J. A. North, A. A. Spector, and G. R. Buettner Glutamate oxidation by trophoblasts in vitro J. A. Broeder, C. H. Smith, and A. J. Moe 31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate R. J. Gillies, Z. Liu, and Z. Bhujwalla Lysophosphatidic acids induce proliferation of cultured vascular smooth muscle cells from rat aorta A. Tokumura, M. Iimori, Y. Nishioka, M. Kitahara, M. Sakashita, and S. Tanaka Genetic control of erythrocyte volume regulation: effect of a single gene (rol) on cation metabolism P. R. Fernandes and M. J. Dewey Calcium release by cholecystokinin analogue OPE is IP; dependent in single rat pancreatic acinar cells H. Y. Gaisano, D. Wong, L. Sheu, and J. K. Foskett Coordination of nuclear and mitochondrial gene expression during the development of cardiac hypertrophy in rats R. J. Wiesner, V. Aschenbrenner, J. C. Riiegg, and R. Zak Regulation of calcium mobilization and entry in human platelets by endothelium-derived factors J. Geiger, C. Nolte, and U. Walter Mitochondrial biogenesis and development of respiratory chain enzymes in kidney cells: role of glucocorticoids F. Djouadi, J. Bastin, T. Gilbert, A. Rétig, P. Rustin, and C. Merlet-Benichou Potentiation of Ca?*+-activated secretory activity by acAMP-mediated mechanism in avian salt gland cells S. C. Martin, J. Thompson, and T. J. Shuttleworth Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion M. McManus, C. Serhan, P. Jackson, and K. Strange Heterotrimeric G proteins, vesicle trafficking, and CFTR Cl- channels E. M. Schwiebert, F. Gesek, L. Ercolani, C. Wjasow, D. C. Gruenert, K. Karlson, and B. A. Stanton Skeletal muscle junctional membrane protein content in pigs with different ryanodine receptor genotypes J. R. Mickelson, J. M. Ervasti, L. A. Litterer, K. P.C ampbell, and C. F. Louis Anomalies in ion transport in CF mouse tracheal epithelium B. R. Grubb, A. M. Paradiso, and R. C. Boucher RAPID COMMUNICATIONS Expression of a rabbit renal ascorbic acid transporter in Xenopus laevis oocytes D. L. Dyer, Y. Kanai, M. A. Hediger, S. A. Rubin, and H. M. Said Cardiac sarcolemmal Na/Ca-inhibiting peptides XIP and FMRF-amide also inhibit Na/Ca exchange in squid axons R. DiPolo and L. Beaugé ANNOUNCEMENTS No. 2. AUGUST 1994 INVITED REVIEW Mitochondrial calcium transport: physiological and pathological relevance T. E. Gunter, K. K. Gunter, S.-S. Sheu, and C. E. Gavin Subcellular localization of CFTR to endosomes in a ductal epithelium P. Webster, L. Vanacore, A. C. Nairn, and C. R. Marino Adrenergic modulation of intracellular pH in isolated brown fat cells from hamster and rat S. C. Lee, J. S. Hamilton, T. Trammell, B. A. Horwitz, and P. A. Pappone Local ATP regeneration is important for sarcoplasmic reticulum Ca?+ pump function P. Korge and K. B. Campbell Determinants of apical membrane permeabilities of barrier epithelia M. B. Lande, N. A. Priver, and M. L. Zeidel Characterization of the proteins of the intestinal Na*+-K*-2Cl- cotransporter W. Suvitayavat, P. B. Dunham, M. Haas, and M. C. Rao Transport and interaction of nitrogen oxides and NO, with CO.-HCO; transporters in pancreatic acini H. Zhao, X. Xu, K. Ujiie, R. A. Star, and S. Muallem Hepatocyte inducible nitric oxide synthesis is influenced in vitro by cell density A. K. Nussler, Z.-Z. Liu, M. Di Silvio, M. A. Sweetland, D. A. Geller, J. R. Lancaster, Jr., T. R. Billiar, P. D. Freeswick, C. L. Lowenstein, and R. L. Simmons Interferon-y induces a cell surface phenotype switch on T84 intestinal epithelial cells S. P. Colgan, C. A. Parkos, J. B. Matthews, L. D’Andrea, C. S. Awtrey, A. H. Lichtman, C. Delp-Archer, and J. L. Madara Calcium channels in excitable cells: divergent genotypic and phenotypic expression of a;-subunits A. Liévano, A. Bolden, and R. Horn Thermal stress induces epithelial permeability P. L. Moseley, C. Gapen, E. S. Wallen, M. E. Walter, and M. W. Peterson Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells A. Rich, G. Farrugia, and J. L. Rae Coordinate changes in C protein and myosin expression during skeletal muscle hypertrophy K. M. McCormick, K. M. Baldwin, and F. Schachat Glucocorticoids regulate the transcription of Na+-K*-ATPase genes in the infant rat kidney Z.-M. Wang, M. Yasui, and G. Celsi Ca?*-permeable channel associated with platelet-derived growth factor receptor in mesangial cells H. Matsunaga, B. N. Ling, and D. C. Eaton Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa X. Zheng, M. Geiger, S. Ecke, E. Bielek, P. Donner, U. Eberspdcher, W.-D. Schleuning, and B. R. Binder Determinants of apical membrane formation and distribution in multicellular epithelial MDCK cysts A. Z. Wang, J. C. Wang, G. K. Ojakian, and W. J. Nelson Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase Y. Akai, T. Homma, K. D. Burns, T. Yasuda, K. F. Badr, and R. C. Harris Coupled secretion of chloride and mucus in skin of Xenopus laevis: possible role for CFTR J. F. Engelhardt, S. S. Smith, E. Allen, J. R. Yankaskas, D. C. Dawson, and J. M. Wilson Phorbol myristate acetate and ATP-sensitive potassium channels in insulin-secreting cells M. J. Dunne Isometric, shortening, and lengthening contractions of muscle fiber segments from adult and old mice S. V. Brooks and J. A. Faulkner Further characterization of the sorbitol permease in PAP-HT25 cells S. Napathorn and K. R. Spring Regulation of rat ventricular myosin heavy chain expression by serum and contractile activity M. Qi, K. Ojamaa, E. G. Eleftheriades, I. Klein, and A. M. Samarel Hypertonic upregulation of amino acid transport system A in vascular smooth muscle cells J.-G. Chen, L. R. Klus, D. K. Steenbergen, and S. A. Kempson Modulation of growth factor and cytokine-induced increases in T84 cell monolayer permeability by media components J. A. McRoberts and N. E. Riley Voltage-dependent ionic conductances in Chinese hamster ovary cells R. Skryma, N. Prevarskaya, P. Vacher, and B. Dufy Early effects of PRL on ion conductances in CHO cells expressing PRL receptor N. Prevarskaya, R. Skryma, P. Vacher, N. Daniel, C. Bignon, J. Djiane, and B. Dufy Intercellular communication between mouse Leydig cells W. A. Varanda and A. C. Campos de Carvalho Characterization of gap junctions between pairs of Leydig cells from mouse testis E. M. Pérez-Armendariz, M. C. Romano, J. Luna, C. Miranda, M. V. L. Bennett, and A. P. Moreno Relationship between intra- and extracellular pH in primary cultures of rat astrocytes P. Mellergard, Y. Ou-Yang, and B. K. Siesjé Mammalian a,;-subunit of Na+-K*-ATPase does not need its amino terminus to maintain cell viability N. M. Shanbaky and T. A. Pressley Delayed activation of single mechanosensitive channels in Lymnaea neurons D. L. Small and C. E. Morris The effect of [Arg*]vasopressin on electrogenic chloride secretion in cultured rat epididymal epithelia K. B. Lai, W. O. Fu, W. H. Ko, H. C. Chan, and P. Y. D. Wong Sarcoplasmic reticulum Ca?* pump expression in denervated skeletal muscle L. Schulte, D. Peters, J. Taylor, J. Navarro, and S. Kandarian Tension-voltage relations of single myocytes reflect Ca release triggered by Na/Ca exchange at 35°C but not 23°C M. Vornanen, N. Shepherd, and G. Isenberg Elevated extracellular Mg?* increases Mg?* buffering through a Ca-dependent mechanism in cardiomyocytes K. L. Koss and R. D. Grubbs Dissociation of depolarization-activated and swelling-activated Cl- channels M. E. Krouse, C. M. Haws, Y. Xia, R. H. Fang, and J. J. Wine Selection for MDR1/P-glycoprotein enhances swelling-activated K* and Cl- currents in NIH/3TS3 cells D. B. Luckie, M. E. Krouse, K. L. Harper, T. C. Law, and J. J. Wine No. 3. SEPTEMBER 1994 INVITED REVIEW Signal transduction in vascular smooth muscle: diacylglycerol second messengers and PKC action M. W. Lee and D. L. Severson Shear stress inhibits adhesion of cultured mouse endothelial cells to lymphocytes by downregulating VCAM-1 expression J. Ando, H. Tsuboi, R. Korenaga, Y. Takada, N. Toyama-Sorimachi, M. Miyasaka, and A. Kamiya ATP is not required for anion current activated by cell swelling in multidrug-resistant lung cancer cells J. D. Jirsch, D. W. Loe, S. P. C. Cole, R. G. Deeley, and D. Fedida Differential expression of I,, mRNAs in mouse tissue during development and pregnancy A. Felipe, T. J. Knittle, K. L. Doyle, D. J. Snyders, and M. M. Tamkun Polyamines influence transglutaminase activity and cell migration in two cell lines S. A. McCormack, J.-Y. Wang, M. J. Viar, L. Tague, P. J. A. Davies, and L. R. Johnson Polyamine deficiency causes reorganization of F-actin and tropomyosin in IEC-6 cells S. A. McCormack, J.-Y. Wang, and L. R. Johnson Regulation of parathyroid hormone-related peptide production in normal human mammary epithelial cells in vitro M. Sebag, J. Henderson, D. Goltzman, and R. Kremer Identification of A; adenosine receptors in rat cochlea coupled to inhibition of adenylyl cyclase V. Ramkumar, R. Ravi, M. C. Wilson, T. W. Gettys, C.W hitworth, and L. P. Rybak Participation of Na* channels in the response of carotid body chemoreceptor cells to hypoxia A. Rocher, A. Obeso, M. T. G. Cachero, B. Herreros, and C. Gonzdlez Activity and density of the Na*/H* antiporter in normal and transformed human lymphocytes and fibroblasts M. Siczkowskhi, J. E. Davies, and L. L. Ng Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells M. J. Kuchan, H. Jo, and J. A. Frangos Effect of isosmotic removal of extracellular Na* on cell volume and membrane potential in muscle cells C. Pena-Rasgado, J. C. Summers, K. D. McGruder, J. DeSantiago, and H. Rasgado-Flores Effect of isosmotic removal of extracellular Ca2* and of membrane potential on cell volume in muscle cells C. Peria-Rasgado, K. D. McGruder, J. C. Summers, and H. Rasgado-Flores cAMP and inositol 1,4,5-trisphosphate increase Ca?* in HT-29 cells by activating different Ca?* influx pathways G. M. Denning, R. A. Clark, and M. J. Welsh Cytoskeletal dissociation of ezrin during renal anoxia: role in microvillar injury J. Chen, R. B. Doctor, and L. J. Mandel Glucocorticoids regulate Na* /H* exchange expression and activity in region- and tissue-specific manner J. H. Cho, M. W. Musch, A. M. DePaoli, C. M. Bookstein, Y. Xie, C. F. Burant, M. C. Rao, and E. B. Chang Ontogeny of cationic amino acid transport systems in rat placenta M. S. Malandro, M. J. Beveridge, M. S. Kilberg, and D. A. Novak A basolateral CHIP28/MIP26-related protein (BLIP) in kidney principal cells and gastric parietal cells G. Valenti, J.-M. Verbavatz, I. Sabolié, D. A. Ausiello, A. S. Verkman, and D. Brown Anti-idiotypic antibodies to delineate epitope specificity of anti-amiloride antibodies C. Lin, M. Musch, P. Meo, J. Zebrowitz, E. Chang, and T. R. Kleyman Development of soleus muscles in SHR: relationship of muscle deficits to rise in blood pressure A. Atrakchi, S. D. Gray, and R. C. Carlsen Increased Na*-K* pump number and decreased pump activity in soleus muscles in SHR J. G. Pickar, R. C. Carlsen, A. Atrakchi, and S. D. Gray pH; and serum regulate AE2-mediated Cl- /HCO; exchange in CHOP cells of defined transient transfection status L. Jiang, A. Stuart-Tilley, J. Parkash, and S. L. Alper SPECIAL COMMUNICATION Slowly activating voltage-dependent K* conductance is apical pathway for K* secretion in vestibular dark cells D. C. Marcus and Z. Shen RAPID COMMUNICATION Clenbuterol, a B:-agonist, retards wasting and loss of contractility in irradiated dystrophic mdx muscle R. J. Zeman, Y. Zhang, and J. D. Etlinger No. 4. OCTOBER 1994 INVITED REVIEW The Na-K-Cl cotransporters M. Haas Responses to extracellular ATP of lymphoblastoid cell lines from Duchenne muscular dystrophy patients D. Ferrari, M. Munerati, L. Melchiorri, S. Hanau, F. Di Virgilio, and O. R. Baricordi Alveolar epithelial cells regulate the induction of endothelial cell apoptosis C. H. Wendt, V. A. Polunovsky, M. S. Peterson, P. B. Bitterman, and D. H. Ingbar Expression of Na*-K+-ATPase a- and 8-subunits along rat nephron: isoform specificity and response to hypokalemia A. A. McDonough, C. E. Magyar, and Y. Komatsu Female sex hormones inhibit volume regulation in rat brain astrocyte culture C. L. Fraser and R. A. Swanson NMER-visible intracellular P; and phosphoesters during regulation of Na*-P; cotransport in opossum kidney cells M. Barac-Nieto and A. Spitzer Depletion of intracellular Ca?* stores activates a Ca?+-selective channel in vascular endothelium L. Vaca and D. L. Kunze In vivo upregulation of adipocyte a.-adrenoceptors by androgens is consequence of direct action on fat cells A. Bouloumié, P. Valet, M. Dauzats, M. Lafontan, and J.-S. Saulnier-Blache Insulin activates furosemide-sensitive K* and Cl- uptake system in BC3H1 cells E. Weil-Maslansky, Y. Gutman, and S. Sasson Renal cells transformed with SV40 contain a high-conductance calcium-insensitive potassium channel J. Teulon, P. M. Ronco, and A. Vandewalle Heparin induces endothelial extracellular matrix alterations and barrier dysfunction H.-J. Guretzki, E. Schleicher, K.-D. Gerbitz, and B. Olgeméller Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle S. R. Price, B. K. England, J. L. Bailey, K. Van Vreede, and W. E. Mitch Extracellular Ca?* sensing is modulated by pH in human osteoclast-like cells in vitro M. Grano, R. Faccio, S. Colucci, R. Paniccia, N. Baldini, A. Z. Zallone, and A. Teti Coexisting B-adrenoceptor subtypes: significance for thermogenic process in brown fat cells J. Zhao, L. Unelius, T. Bengtsson, B. Cannon, and J. Nedergaard Redistribution of protein kinase C isoforms in association with vascular hypertrophy of rat aorta Y.-M. Liou and K. G. Morgan Salt stress increases abundance and glycosylation of CFTR localized at apical surfaces of salt gland secretory cells S. A. Ernst, K. M. Crawford, M. A. Post, and J. A. Cohn Labeling of the Amphiuma erythrocyte K* /H* exchanger with H,DIDS H. M. Maldonado and P. M. Cala Mammalian urinary bladder permeability is altered by cationic proteins: modulation by divalent cations C. J. Tzan, J. R. Berg, and S. A. Lewis Disruptive effects of protein on performance of liquid membrane-based ion-selective microelectrodes H. V. Coombs, A. J. Miller, and D. Sanders Modulation of ATP-sensitive K* channels by internal acidification in insulin-secreting cells Z. Fan, Y. Tokuyama, and J. C. Makielski Regulatory volume decrease in HL-60 cells: importance of rapid changes in permeability of Cl- and organic solutes K. R. Hallows and P. A. Knauf Control of intracellular pH during regulatory volume decrease in HL-60 cells K. R. Hallows, D. Restrepo, and P. A. Knauf Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2 J. Geisel, J. A. Cook, S. H. Ashton, W. C. Wise, and P. V. Halushka Decreased protein phosphorylation induced by anoxia in proximal renal tubules C. E. Kobryn and L. J. Mandel Large Ca?*-activated K* channels responsive to angiotensin II in cultured human mesangial cells J. D. Stockand and S. C. Sansom G protein effects on Ca?* release and excitation-contraction coupling in skeletal muscle fibers L. Carney-Anderson and S. K. Donaldson ATP-activated chloride channel inhibited by an antibody to P glycoprotein J. J. Zhang and T. J. C. Jacob Voltage-activated potassium currents of rabbit osteoclasts: effects of extracellular calcium L. G. Hammerland, A. S. Parihar, E. F. Nemeth, and M. C. Sanguinetti MCP-1-stimulated monocyte attachment to laminin is mediated by B2-integrins Y. Jiang, J.-F. Zhu, F. W. Luscinskas, and D. T. Graves Na*-coupled alanine transport in LLC-PK, cells G. A. Kimmich, J. Randles, and J. Wilson Endothelins stimulate mitogen-activated protein kinase cascade through either ET, or ET, Y. Wang, P. M. Rose, M. L. Webb, and M. J. Dunn Intracellular Cl activity: evidence of dual mechanisms of C] absorption in sweat duct M. M. Reddy and P. M. Quinton SPECIAL COMMUNICATIONS Methods for determining cardiac sarcoplasmic reticulum Ca?* pump kinetics from fura 2 measurements M. E. Kargacin and G. J. Kargacin Method for manipulation of cytosolic pH in cells clamped in the whole cell or perforated-patch configurations S. Grinstein, R. Romanek, and O. D. Rotstein RAPID COMMUNICATION Rapid turnover of myosin light chain phosphate during cross-bridge cycling in smooth muscle T. M. Butler, S. R. Narayan, S. U. Mooers, and M. J. Siegman No. 5. NOVEMBER 1994 INVITED REVIEW Potential assays for sperm capacitation in mammals A. Cohen-Dayag and M. Eisenbach Different effects of gradual vs. acute adenine nucleotide depletion on ATP cost of muscle contraction J. M. Foley, G. R. Adams, and R. A. Meyer Endothelin receptors in human smooth muscle cells: antagonist potency differs on agonist-evoked responses J. R. Wu-Wong, W. J. Chiou, Z.-J. Huang, M. J. Vidal, and T. J. Opgenorth Muscarinic stimulation of gallbladder epithelium. III. Antagonism of cAMP-mediated effects G. A. Altenberg, M. Subramanyam, and L. Reuss The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding P. S. Jackson, R. Morrison, and K. Strange Spatial and temporal variations in local spike propagation in the myometrium of the 17-day pregnant rat W. J. E. P. Lammers, K. Arafat, A. El-Kays, and T. Y. El-Sharkawy Protein kinase C activity does not mediate the inhibitory effect of carbachol on chloride secretion by T84 cells A. E. Traynor-Kaplan, T. Buranawuti, M. Vajanaphanich, and K. E. Barrett Cloning and characterization of a K,1.5 delayed rectifier K* channel from vascular and visceral smooth muscles K. E. Overturf, S. N. Russell, A. Carl, F. Vogalis, P. J. Hart, J. R. Hume, K. M. Sanders, and B. Horowitz Angiotensin II-dependent proximal tubule sodium transport is mediated by cAMP modulation of phospholipase C J. R. Schelling, H. Singh, R. Marzec, and S. L. Linas Capacitative Ca?* influx in adrenal glomerulosa cells: possible role in angiotensin II response T. Rohacs, A. Bago, F. Deék, L. Hunyady, and A. Spat Caffeine stimulation of malignant hyperthermia-susceptible sarcoplasmic reticulum Ca?* release channel N. H. Shomer, J. R. Mickelson, and C. F. Louis Agonist-induced redistribution of calponin in contractile vascular smooth muscle cells C. A. Parker, K. Takahashi, T. Tao, and K. G. Morgan Ca?*-mobilizing hormones potentiate hypotonicity-induced activation of ionic conductances in Intestine 407 cells B. C. Tilly, M. J. Edixhoven, N. van den Berghe, A. G. M. Bot, and H. R. de Jonge Nat-dependent and Na*-independent systems of choline transport by plasma membrane vesicles of A549 cell line A. Kleinzeller, C. Dodia, A. Chander, and A. B. Fisher Fast sodium currents induced by serum in human uterine leiomyosarcoma cells M. Kusaka and N. Sperelakis Functional characterization and regulation by pH of murine AE2 anion exchanger expressed in Xenopus oocytes B. D. Humphreys, L. Jiang, M. N. Chernova, and S. L. Alper Involvement of protein kinase C and Ca?* in angiotensin I]-induced mitogenesis of cardiac fibroblasts G. W. Booz, D. E. Dostal, H. A. Singer, and K. M. Baker Opposite roles of cAMP and cGMP on volume loss in muscle cells C. Peria-Rasgado, V. A. Kimler, K. D.M cGruder, J. Tie, and H. Rasgado-Flores Endothelin receptor in osteoblastic cells is coupled to multiple messenger signals J. Green, O. Foellmer, C. R. Kleeman, and M. M. Basic Agonist-induced changes of [Ca?*]; and membrane currents in single bovine aortic endothelial cells H. M. Himmel, R. L. Rasmusson, and H. C. Strauss Expression and function of P-glycoprotein in human mesangial cells E. Bello-Reuss and S. Ernest Interactions between inhibitory and excitatory modulatory signals in single submucosal neurons C. Barajas-Lépez Loss of red blood cell glutathione during Mg deficiency: prevention by vitamin E, D-propranolol, and chloroquine I. T. Mak, R. Stafford, and W. B. Weglicki Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides L. K. Moore and J. M. Burt Regulation of endothelial nitric oxide synthase mRNA, protein, and activity during cell growth J.-F. Arnal, J. Yamin, S. Dockery, and D. G. Harrison Angiotensin II type 2 receptor stimulation of neuronal K* currents involves an inhibitory GTP binding protein J. Kang, P. Posner, and C. Sumners Interferon-y downregulates CFTR gene expression in epithelial cells F. Besancon, G. Przewlocki, I. Baré, A.-S. Hongre, D. Escande, and A. Edelman Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP T. L. Cornwell, E. Arnold, N. J. Boerth, and T. M. Lincoln Effects of prostaglandin E2 on amiloride-blockable Na* channels in a distal nephron cell line (A6) K. E. Kokko, P. S. Matsumoto, B. N. Ling, and D. C. Eaton Effects of EGTA on calcium signaling in airway epithelial cells R. A. Harris and J. W. Hanrahan Calcium-activated sodium and chloride fluxes modulate platelet volume: role of Ca?* stores B. P. Fine, E. S. Marques, and K. A. Hansen Multiple modes of regulation of airway epithelial chloride secretion by extracellular ATP M. J. Stutts, J. G. Fitz, A.M . Paradiso, and R. C. Boucher Ketamine inhibition of large conductance Ca?*-activated K* channels is modulated by intracellular Ca?* D. D. Denson and D. C. Eaton Kinetics of prostacyclin synthesis in PGHS-1-overexpressed endothelial cells S. K. Sanduja, A.-L. Tsai, N. Matijevic-Aleksic, and K. K. Wu Progesterone and EGF inhibit mouse mammary gland prolactin receptor and B-casein gene expression S. Nishikawa, R. C. Moore, N. Nonomura, and T. Oka Direct measurement of extracellular proton flux from isolated gastric glands A. Thibodeau, R. C. Kuo, J. M. Crothers, Jr., X. Yao, J. C. Owicki, and J. G. Forte Permeability properties of the mammalian bladder apical membrane A. Chang, T. G.H ammond, T. T. Sun, and M. L. Zeidel Response to osmotic stimuli in mesangial cells: role of system A transporter A. Yamauchi, A. Miyai, K. Yokoyama, T. Itoh, T. Kamada, N. Ueda, and Y. Fujiwara RAPID COMMUNICATION Activation of recombinant trp by thapsigargin in Sf9 insect cells L. Vaca, W. G. Sinkins, Y. Hu, D. L. Kunze, and W. P. Schilling No. 6. DECEMBER 1994 INVITED REVIEW Antidiuretic hormone and exocytosis: lessons from neurosecretion R. M. Hays, N. Franki, H. Simon, and Y. Gao Carrier-mediated transport of lipoxin A, in human neutrophils L. Simchowitz, S. Fiore, and C. N. Serhan Swelling-activated K+ fluxes in vascular endothelial cells: role of intracellular Ca?* P. B. Perry and W. C. O’Neill Role of external Na* and cvtosolic pH in agonist-evoked cytosolic Ca?* response in human platelets M. Kimura, K. Nakamura, J. W. Fenton II, T. T. Andersen, J. P. Reeves, and A. Aviv Protein kinase C inhibits Na*-K*-2Cl- cotransporter activity in cultured rabbit nonpigmented ciliary epithelium J. Dong and N. A. Delamere Lactate transport mechanisms at apical and basolateral membranes of bovine retinal pigment epithelium E. Kenyon, K. Yu, M. la Cour, and S. S. Miller Serine/threonine kinase activation in human neutrophils: relationship to tyrosine phosphorylation J. H. Brumell and S. Grinstein Role of redox systems on Fe*+ uptake by transformed human intestinal epithelial (Caco-2) cells M. T. Niinez, X. Alvarez, M. Smith, V. Tapia, and J. Glass Aminopyridine inhibition and voltage dependence of K* currents in smooth muscle cells from cerebral arteries B. E. Robertson and M. T. Nelson Effect of series elasticity on delay in development of tension relative to stiffness during muscle activation Y. Luo, R. Cooke, and E. Pate Cl--dependent NH; transport mechanisms in medullary thick ascending limb cells H. Amlal, M. Paillard, and M. Bichara Potassium cotransport at the rat choroid plexus R. F. Keep, J. Xiang, and A. L. Betz Migration-associated volume changes in neutrophils facilitate the migratory process in vitro S. Rosengren, P. M. Henson, and G. S. Worthen K*-induced alkalinization in mouse cerebral astrocytes mediated by reversal of electrogenic Na*-HCO,; cotransport N. Brookes and R. J. Turner Role of protein phosphorylation in control of K flux pathways of trout red blood cells A. R. Cossins, Y. R. Weaver, G. Lykkeboe, and O. B. Nielsen Thyroid hormones modulate both adenosine transport and adenosine A, receptors in rat brain M. D. Fideu, A. Arce, A. I. Esquifino, and M. T. Miras-Portugal Mechanosensitive modulation of myosin phosphorylation and phosphatidylinositol turnover in smooth muscle J. Yoo, R. Ellis, K. G. Morgan, and C.-M. Hai Sources of calcium utilized in cholinergic responses in canine colonic smooth muscle K. Sato, K. M. Sanders, W. T. Gerthoffer, and N. G. Publicover Patterns of tyrosine phosphorylation differ in vascular hypertrophy and hyperplasia S. Ali and G. W. Dorn II Membrane topology of the epithelial sodium channel in intact cells C. M. Canessa, A.-M. Merillat, and B. C. Rossier