TABLE OF CONTENTS JULY TO DECEMBER, 1991 Number 1, July 1991 Editorials Intraoperative Cytology: Back to the Future? MARY K. SIDAWY AND STEVEN G. SILVERBERG Parvovirus B19, Hydrops Fetalis, and Fetal Wastage: An Etiologic Sequence LOU!S P. DEHNER ANATOMIC PATHOLOGY Original Articles Intraoperative Surgical Specimen Evaluation: Frozen Section Analysis, Cytologic Examination, or Both? A Comparative Study of 206 Cases SHARON MAIR, RICHARD H. LASH, DANI SUSKIN, AND GEOFFREY MENDELSOHN Anaplastic Thyroid Carcinoma: Immunocytochemical Study of 32 Cases NELSON G. ORDONEZ, ADEL K. EL-NAGGAR, ROBERT C. HICKEY, AND NAGUIB A. SAMAAN The Human Hematopoietic Progenitor Cell Antigen (CD-34) in Vascular Neoplasia S. THOMAS TRAWEEK, PATRICIA L. KANDALAFT, PARULA MEHTA, AND HECTOR BATTIFORA Comparative Immunohistochemical Staining for Desmin and Muscle-Specific Actin: A Study of 576 Cases SAMREUNG RANGDAENG AND LUAN D. TRUONG Expression of a Polymorphic Epithelial Mucin Antigen Defined by the Monoclonal Antibody BC2 in Ovarian Carcinoma: Use of the BC2 Antibody for the Detection of Micrometastases MICHAEL A. MCGUCKIN, GORDON WRIGHT, AND BRUCE G. WARD Comparison of Monoclonal Immunocytochemical and Immunoenzymatic Methods for Steroid Receptor Evaluation in Breast Cancer FERDINANDO DE NEGRI, DANIELA CAMPANI, ROBERTA SARNELLI, LEONARDO MARTINI, AGOSTINO GIGLIOTTI, ROSANNA BONACCI, RAFFAELLA FABBRI, FRANCESCO SQUARTINI, ALDO PINCHERA, AND CLAUDIO GIANI Immunocytochemical Analysis of Progesterone Receptors in Breast Cancer SHAHLA MASOOD, SUPRANEE DEE, AND JEFFREY D. GOLDSTEIN Automated Procedure for Dewaxing and Rehydration of Paraffin-Embedded Tissue Sections for DNA Flow Cytometric Analysis of Breast Tumors JEANNETTE BABIAK AND SIBRAND POPPEMA Correlation Between Visual Clues, Objective Architectural Features, and Interobserver Agreement in Prostate Cancer CELSO DI LORETO, BRENDAN FITZPATRICK, SHELLY UNDERHILL, DAE H. KIM, HARVEY E. DYTCH, HUGO GALERA-DAVIDSON, AND MARLUCE BIBBO Diagnostic Problems in Tissues Previously Sampled by Fine-needle Aspiration SANA O. TABBARA, HENRY F. FRIERSON, JR., AND ROBERT E. FECHNER HEMATOPATHOLOGY Original Articles Composite Lymphoma: A Clinicopathologic Analysis of Nine Patients with Hodgkin’s Disease and B-Cell Non-Hodgkin’s Lymphoma CHRISTOPHER L. GONZALEZ, L. JEFFREY MEDEIROS, AND ELAINE S. JAFFE Aberrant MT2 Positivity Distinguishes Follicular Lymphoma from Reactive Follicular Hyperplasia in B5- and Formalin-Fixed Paraffin Sections GARVAN BROWNE, BRENDAN TOBIN, DESMOND N. CARNEY, AND PETER A. DERVAN The Predictive Value of Bone Marrow Morphologic Characteristics and Immunostaining in Primary (AL) Amyloidosis SAM S.-H. WU, KATHLEEN BRADY, JENNIFER J. ANDERSON, RICHARD VEZINA, MARTHA SKINNER, RICHARD S. NEIMAN, AND BARBARA C. WOLF The Expression of CD22 (Leu 14) and CD1 1c (LeuMS5) in Chronic Lymphoproliferative Disorders Using Two-Color Flow Cytometric Analysis MICHAEL L. MILLER, ANDREW J. FISHLEDER, AND RAYMOND R. TUBBS TABLE OF CONTENTS JULY TO DECEMBER, 1991 Number 1, July 1991 Editorials Intraoperative Cytology: Back to the Future? MARY K. SIDAWY AND STEVEN G. SILVERBERG Parvovirus B19, Hydrops Fetalis, and Fetal Wastage: An Etiologic Sequence LOU!S P. DEHNER ANATOMIC PATHOLOGY Original Articles Intraoperative Surgical Specimen Evaluation: Frozen Section Analysis, Cytologic Examination, or Both? A Comparative Study of 206 Cases SHARON MAIR, RICHARD H. LASH, DANI SUSKIN, AND GEOFFREY MENDELSOHN Anaplastic Thyroid Carcinoma: Immunocytochemical Study of 32 Cases NELSON G. ORDONEZ, ADEL K. EL-NAGGAR, ROBERT C. HICKEY, AND NAGUIB A. SAMAAN The Human Hematopoietic Progenitor Cell Antigen (CD-34) in Vascular Neoplasia S. THOMAS TRAWEEK, PATRICIA L. KANDALAFT, PARULA MEHTA, AND HECTOR BATTIFORA Comparative Immunohistochemical Staining for Desmin and Muscle-Specific Actin: A Study of 576 Cases SAMREUNG RANGDAENG AND LUAN D. TRUONG Expression of a Polymorphic Epithelial Mucin Antigen Defined by the Monoclonal Antibody BC2 in Ovarian Carcinoma: Use of the BC2 Antibody for the Detection of Micrometastases MICHAEL A. MCGUCKIN, GORDON WRIGHT, AND BRUCE G. WARD Comparison of Monoclonal Immunocytochemical and Immunoenzymatic Methods for Steroid Receptor Evaluation in Breast Cancer FERDINANDO DE NEGRI, DANIELA CAMPANI, ROBERTA SARNELLI, LEONARDO MARTINI, AGOSTINO GIGLIOTTI, ROSANNA BONACCI, RAFFAELLA FABBRI, FRANCESCO SQUARTINI, ALDO PINCHERA, AND CLAUDIO GIANI Immunocytochemical Analysis of Progesterone Receptors in Breast Cancer SHAHLA MASOOD, SUPRANEE DEE, AND JEFFREY D. GOLDSTEIN Automated Procedure for Dewaxing and Rehydration of Paraffin-Embedded Tissue Sections for DNA Flow Cytometric Analysis of Breast Tumors JEANNETTE BABIAK AND SIBRAND POPPEMA Correlation Between Visual Clues, Objective Architectural Features, and Interobserver Agreement in Prostate Cancer CELSO DI LORETO, BRENDAN FITZPATRICK, SHELLY UNDERHILL, DAE H. KIM, HARVEY E. DYTCH, HUGO GALERA-DAVIDSON, AND MARLUCE BIBBO Diagnostic Problems in Tissues Previously Sampled by Fine-needle Aspiration SANA O. TABBARA, HENRY F. FRIERSON, JR., AND ROBERT E. FECHNER HEMATOPATHOLOGY Original Articles Composite Lymphoma: A Clinicopathologic Analysis of Nine Patients with Hodgkin’s Disease and B-Cell Non-Hodgkin’s Lymphoma CHRISTOPHER L. GONZALEZ, L. JEFFREY MEDEIROS, AND ELAINE S. JAFFE Aberrant MT2 Positivity Distinguishes Follicular Lymphoma from Reactive Follicular Hyperplasia in B5- and Formalin-Fixed Paraffin Sections GARVAN BROWNE, BRENDAN TOBIN, DESMOND N. CARNEY, AND PETER A. DERVAN The Predictive Value of Bone Marrow Morphologic Characteristics and Immunostaining in Primary (AL) Amyloidosis SAM S.-H. WU, KATHLEEN BRADY, JENNIFER J. ANDERSON, RICHARD VEZINA, MARTHA SKINNER, RICHARD S. NEIMAN, AND BARBARA C. WOLF The Expression of CD22 (Leu 14) and CD1 1c (LeuMS5) in Chronic Lymphoproliferative Disorders Using Two-Color Flow Cytometric Analysis MICHAEL L. MILLER, ANDREW J. FISHLEDER, AND RAYMOND R. TUBBS TABLE OF CONTENTS Comparison of an Isoelectric Focusing Technique and High-Performance Liquid Chromotography for Determination of Fetal Hemoglobin Levels ENID F. GILBERT-BARNESS, KATHERINE S. KENISON, EARL SHRAGO, TERRY L. SPENNETTA, AND GARY G. GIULIAN Single Case Reports Auer Rod-like Inclusions in Circulating Lymphoma Cells DEBRA A. GROOM, DONNA WONG, RUSSELL K. BRYNES, AND LINDA K. MACAULAY Clonal Immunoglobulin Gene Rearrangement in the Infarcted Lymph Node Syndrome MICHAEL J. LASZEWSKI, PAUL J. BELDING, RICHARD M. FEDDERSEN, CHARLES T. LUTZ, JAMES A. GOEKEN, JOHN D. KEMP, AND FRED R. DICK CLINICAL MICROBIOLOGY Original Articles Parvovirus B19 Infection of the Fetus: Histology and Jn Situ Hybridization TINO F. SCHWARZ, ANDREAS NERLICH, BARBARA HOTTENTRAGER, GUNDULA JAGER, IRMGARD WIEST, SILKE KANTIMM, HEDWIG ROGGENDORF, MANITA SCHULTZ, KARL-PHILIP GLONING, THOMAS SCHRAMM, WOLFGANG HOLZGREVE, AND MICHAEL ROGGENDORF Early Use of Indirect Immunofluorescence for the Detection of Respiratory Syncytial Virus in HEp-2 Cell Culture KENNETH BROMBERG, GAYLENE TANNIS, AND BENNETT DAIDONE Single Case Report Catalase-Negative Listeria monocytogenes Causing Meningitis in an Adult: Clinical and Laboratory Features MARSHA A. SWARTZ, DAVID F. WELCH, RADHA P. NARAYANAN, AND RONALD A. GREENFIELD CLINICAL CHEMISTRY Original Articles Neural Network Analysis of Serial Cardiac Enzyme Data: A Clinical Application of Artificial Machine Intelligence JAMES W. FURLONG, MILTON E. DUPUY, AND JAMES A. HEINSIMER The Opacity of Portal Hypertension-Related Ascites Correlates with the Fluid’s Triglyceride Concentration BRUCE A. RUNYON, EVANGELOS A. AKRIVIADIS, AND ANTHONY J. KEYSER CORRESPONDENCE AND CORRECTIONS Effect of Fixatives and Fixation Times on Tissues HECTOR BATTIFORA The Authors’ Reply CATHERINE E. GREER AND M. MICHELE MANOS B Cells and UCHL! Antigen Expression ANDREW J. NORTON The Author’s Reply J.D. COTELINGAM Screening RIA Serum Samples PAUL WENTWORTH/RALPH CARMEL The Authors’ Reply JOHN A. RICCIO, DIANE MATURANI, AND MILDRED FLEETWOOD EDTA-Dependent Leukoagglutination SALIM H. KHALIL Thymic B Cells FALKO FEND, DAVID NACHBAUR, AND HEINZ HUBER The Authors’ Reply TADAAKI EIMOTO AND MASAHIRO KIKUCHI NEWS AND NOTICES INFORMATION FOR AUTHORS TABLE OF CONTENTS Number 2, August 1991 Editorials Evolution of the French-American-British (FAB) Proposals. Is There a Place for Acute Basophilic Leukemia? FRED R. DICK Lymphoepithelioma-like Carcinoma and Its Relationship to Epstein-Barr Virus LAWRENCE M. WEISS, MICHAEL J. GAFFEY, AND DARRYL SHIBATA HEMATOPATHOLOGY Original Articles Acute Basophilic Leukemia: A Clinical, Morphologic, and Cytogenetic Study of Eight Cases LoANN C. PETERSON, JANET L. PARKIN, DIANE C. ARTHUR, AND RICHARD D. BRUNNING Fulminant Childhood Hemophagocytic Syndrome Mimicking Histiocytic Medullary Reticulosis: An Atypical Form of Epstein-Barr Virus Infection RONG-LONG CHEN, IH-JEN SU, KAI-HSIN LIN, SHENG-HUANG LEE, DONG-TSAMN LIN, WEN-MIN CHUU, KUO-SIN LIN, LI-MIN HUANG, AND CHIN-YUN LEE Immunoblastic Lymphoma with Abundant Clear Cytoplasm: A Comparative Study of B- and T-Cell Types HIROKAZU NAKAMINE, ANEAL S. MASIH, R. SCOTT STROBACH, MICHAEL J. DUGGAN, MARTIN A. BAST, JAMES O. ARMITAGE, AND DENNIS D. WEISENBURGER Non-Hodgkin’s Lymphomas of Nasal Cavity and Paranasal Sinuses: An Immunohistochemical Study ELIAS CAMPO, ANTONIO CARDESA, LLUCIA ALOS, ANTONIO PALACIN, JOAQUIN COBARRO, JOSE TRASERRA, AND EMILIO MONTSERRAT The Transient Appearance of Small Blastoid Cells in the Marrow after Bone Marrow Transplantation SHOICHI D. KOBAYASHI, KUNIKO SEKI, NORIKO SUWA, CHIYOMI KOAMA, TOSHIHARU YAMAMOTO, KOUDOU AIBA, ATSUO MARUTA, MICHIO MATSUZAKI, HITOSHI FUKAWA, HEIWA KANAMORI, HIROSHI HARANO, HIROKO MIYASHITA, AND FUMIO KODAMA COAGULATION AND TRANSFUSION MEDICINE Single Case Reports A Case of Acquired Factor X Deficiency with Jn Vivo and In Vitro Evidence of Inhibitor Activity Directed Against Factor X PATRICIA E. MULHARE, PAULA B. TRACY, ELIZABETH A. GOLDEN, RICHARD F. BRANDA, AND EDWIN G. BOVILL Red Blood Cell Alloimmunization Complicating Plasma Transfusion ERIC P. CHING, MAN-CHIU POON, DORIS NEURATH, AND BERNARD A. RUETHER CYTOGENETICS Original Article Use of Fluorescent Jn Situ Hybridization for Marker Chromosome Identification in Congenital and Neoplastic Disorders CHRIS R. SCHAD, WILLIAM J. KRAKER, SYED M. JALAL, MARTIN S. TALLMAN, HAROLD N. LONDER, LOLA P. COOK, AND ROBERT B. JENKINS CLINICAL MICROBIOLOGY Single Case Report Achrombacter xylosoxidans: An Unusual Neonatal Pathogen YVONNE R. HEARN AND RITA M. GANDER CLINICAL CHEMISTRY Single Case Report Congenital Atransferrinemia: A Case Report and Review of the Literature RANDY L. HAMILL, JOSEPH C. WOODS, AND BRUCE A. COOK TABLE OF CONTENTS ANATOMIC PATHOLOGY Original Articles Poorly Differentiated Adenocarcinoma with Lymphoid Stroma (Lymphoepithelioma-like Carcinomas) of the Stomach: Report of Three Cases with Epstein-Barr Virus Genome Demonstrated by the Polymerase Chain Reaction KYUNG-WHAN MIN, SONYA HOLMQUIST, STEPHEN C. PEIPER, AND TIMOTHY J. O’LEARY Multitumor “Sausage” Blocks in Immunohistochemistry: Simplified Method of Preparation, Practical Uses, and Roles in Quality Assurance RODNEY T. MILLER AND CAROL L. GROOTHUIS Potential Use of Monoclonal Antibodies in the Diagnostic Distinction of Gynecomastia from Breast Carcinoma in Men MARCELLA MOTTOLESE, GIULIO BIGOTTI, ANTONELLA COLI, CARLO VITUCCI, AND PIER GIORGIO NATALI Expression of Haptoglobin-related Protein in Primary and Metastatic Breast Cancers: A Longitudinal Study of 48 Fatal Tumors MUHAMMAD S. SHURBAJI, GARY R. PASTERNACK, AND FRANCIS P. KUHAJDA Expression of C-erbB-2 Oncoprotein in Mammary and Extramammary Paget’s Disease ROBERT A. WOLBER, BEVERLEY A. DUPUIS, AND MARK R. WICK Cell-Surface Ganglioside GD2 in the Immunohistochemical Detection and Differential Diagnosis of Neuroblastoma HANNU SARIOLA, HARRI TERAVA, JUHANI RAPOLA, AND ULLA M. SAARINEN Single Case Reports Pseudosarcomatous Fibromyxoid Tumor of the Prostate: A Case Report with Immunohistochemical, Electron Microscopic, and DNA Flow Cytometric Analysis AYSEGUL A. SAHIN, JAE Y. RO, ADEL K. EL-NAGGAR, NELSON G. ORDONEZ, RICHARD J. BABAIAN, AND ALBERTO G. AYALA Sex Cord Tumor with Annular Tubules Associated with Endometriosis of the Fallopian Tube LINDA M. GRIFFITH AND MARIA-LUISA CARCANGIU An Autopsy Case of I-Cell Disease: Ultrastructural and Biochemical Analyses HIROYUKI KITAGAWA, JUNKO TOKI, TADANOBU MORIMOTO, TADAYOSHI OKUMURA, KUNIHIKO SAITOH, HIROHIKO HIGASHINO, TSUGIO HORII, YOHNOSUKE KOBAYASHI, AND SUSUMU IKEHARA AWARD ARTICLES AND SPECIAL REPORTS Special Report Assuring Continued Competence: Is Recertification the Way? ROBERT W. McKENNA, GEORGE D. LUNDBERG, JOYCE NUZZO, AND DAVID E. SMITH Inaugural Address President, American Society of Clinical Pathologists C. BARRIE COOK Minutes Minutes of the Annual Business Meeting of the American Society of Clinical Pathologists, Tuesday, October 23, 1990, Dallas, Texas Convention Center BOOK REVIEWS 285 CORRESPONDENCE AND CORRECTIONS Plastic Embedding for Immunohistology TERENCE T. CASEY The Authors’ Reply GRAEME I. MURRAY AND STANLEY W.B. EWEN Plasmacytoid Acute T-Cell Lymphoma/Leukemia FADY K. BADDOURA AND WING C. CHAN The Authors’ Reply CHARLES W. CALDWELL, YOHANNES W. YESUS, TIMOTHY S. LOY, JOHN T. BICKEL, AND MICHAEL C. PERRY Drug-Induced Immune Hemolytic Anemia DONALD R. BRANCH The Authors’ Reply LINDA A. CHAMBERS, LILLIAN M. DONOVAN, AND MARGOT S. KRUSKALL TABLE OF CONTENTS Pneumocystis Ocular Infection MARILYN C. KINCAID Mycobacteria on Wright’s-Stained Smears EMINA TORLAKOVIC AND ELIZABETH D. AMES NEWS AND NOTICES 291 Number 3, September 1991 Editorials The Coming Era of Cytologic Automation JAMES LINDER Immunophenotyping of Hematologic Malignant Conditions: To Flow or Not to Flow? CURTIS A. HANSON ANATOMIC PATHOLOGY Original Articles The Efficacy of an Automated Preparation Device for Cervical Cytology MARTHA L. HUTCHINSON, CLAIRE M. CASSIN, AND HARRISON G. BALL III Dipeptidyl Aminopeptidase IV Staining of Cytologic Preparations to Distinguish Benign from Malignant Thyroid Diseases YATSUKI ARATAKE, TOMIO KOTANI, KAZUO TAMURA, YASUHIKO ARAKI, TADANOBU KURIBAYASHI, KOHKEN KONOE, AND SACHIYA OHTAKI Intratumoral DNA Content Variability: A Study of Non-Small Cell Lung Cancer ATEF SARA AND ADEL K. EL-NAGGAR Human Papillomavirus DNA in Anal Carcinomas: Comparison of Jn Situ and Dot Blot Hybridization MAIRE A. DUGGAN, VALERIE F. BORAS, MASAFUMI INOUE, AND S. ELIZABETH MCGREGOR Distribution of BCA-225 in Adenocarcinomas: An Immunohistochemical Study of 446 Cases TIMOTHY S. LOY, ROBERT K. CHAPMAN, ALBERTO A. DIAZ-ARIAS, IMELDA S. BULATAO, AND JOHN T. BICKEL Geographic Variations in the Histologic Characteristics of the Gastric Mucosa C.A. RUBIO, J. JESSURUM, AND P. ALONSO DE RUIZ Adrenocorticotropic Hormone-Independent Bilateral Adrenocortical Macronodular Hyperplasia as a Distinct Subtype of Cushing’s Syndrome: Enzyme Histochemical and Ultrastructural Study of Four Cases with a Review of the Literature MOTOHIKO AIBA, AKIRA HIRAYAMA, HISAMI IRI, YUKIO ITO, YOSHIHIDE FUJIMOTO, GENGO MABUCHI, MASARU MURAI, HIROSHI TAZAKI, HIROSHI MARUYAMA, TAKAO SARUTA, TOSHIHIRO SUDA, AND HIROSHI DEMURA Single Case Reports Primary Carcinoid of the Common Bile Duct: Immunohistochemical Characterization of a Case and Review of the Literature ARTURO ANGELES-ANGELES, LETICIA QUINTANILLA-MARTINEZ, AND JORGE LARRIVA-SAHD Uterine Leiomyoma with Skeletal Muscle Differentiation: Report of a Case DAVID G. MARTIN-REAY, MIRIAM L. CHRIST, AND ROBERT E. LAPATA Parathyroiditis Associated with Hyperparathyroidism and Branchial Cysts R. CHETTY AND M.D. FORDER HEMATOPATHOLOGY Original Articles Leukemia and Lymphoma Immunophenotyping in Cell Smears with Immunogold-Silver Staining MARC DE WAELE, WIM RENMANS, EDDY SEGERS, KRISTIN JOCHMANS, ISABELLE SALMON, CLAUDE DEPARDIEU, MARIE-FRANCOISE DEHOU, AND BETH VAN CAMP Frozen Sections of Cellular Lymphoid Proliferations Provide Adequate DNA for Routine Gene Rearrangement Analysis GLENN H. SEGAL, ANDREW J. FISHLEDER, MARK H. STOLER, AND RAYMOND R. TUBBS TABLE OF CONTENTS CLINICAL MICROBIOLOGY Original Articles An Evaluation of Three Commercial Fecal Transport Systems for the Recovery of Enteric Pathogens LESLEY S. MUNDY, CAROL J. SHANHOLTZER, KEITH E. WILLARD, AND LANCE R. PETERSON Allergic Fungal Sinusitis: Report of Three Cases Associated with Dematiaceous Fungi GLEN C. FRIEDMAN, R. WARREN J. HARTWICK, JAE Y. RO, GEORGE Y. SALEH, JEFFREY J. TARRAND, AND ALBERTO G. AYALA Immunohistochemical Expression of Galactomannan in the Cytoplasm of Phagocytic Cells During Invasive Aspergillosis GERALD E. PIERARD, JORGE ARRESE ESTRADA, CLAUDINE PIERARD-FRANCHIMONT, ALBERT THIRY, AND DIRK STYNEN The Impact of a Clinic for Adults with HIV Infection on the Microbiology Laboratory JOHN E. MCGOWAN, Jr., SUMNER E. THOMPSON III, BEVERLY G. METCHOCK, CURTIS MORRISS, AND DAVID H. VROON Single Case Report Failure of Dithiothreitol and Pronase to Reveal a False-Positive Cryptococcal Antigen Determination in Cerebrospinal Fluid MARK K. SACHS, C.M. HUANG, DAVID OST, AND DONALD L. JUNGKIND COAGULATION AND TRANSFUSION MEDICINE Original Articles Rapid Removal of Heparin from Plasma by Affinity Filtration BARRY WENZ AND EDWARD R. BURNS Improved Neutrophi! Separation from Anti-D-Treated Rh(D)-Positive Whole Blood by a Discontinuous Gradient Method MICHELE SCHINELLA Single Case Report Plasmapheresis: A Therapeutic Option in the Management of Heparin-Associated Thrombocytopenia with Thrombosis JAMES BRADY, JOHN A. RICCIO, OMAR H. YUMEN, ADEL Z. MAKARY, AND STEVEN M. GREENWOOD CLINICAL CHEMISTRY Original Article Air-Exposed Urine Dipsticks Give False-Positive Results for Glucose and False-Negative Results for Blood HERBERT T. COHEN AND DAVID M. SPIEGEL BOOK REVIEWS 401 ABSTRACTS OF PAPERS 402 Abstracts of Paper and Poster Presentations, Scientific Sessions of the Fall Meeting of the American Society of Clinical Pathologists and the College of American Pathologists, September 21-27, 1991, New Orleans, Louisana CORRESPONDENCE AND CORRECTIONS Free Protein S and C4b Binding Protein C.J. LUSH, L. ARMSTRONG, V.E. MITCHELL The Author’s Reply J. ROGER EDSON How Should Bromodeoxyuridine Labeling Be Counted? JAMES J. GOING The Author’s Reply ANN D. THOR AND BELEN LLOVERAS Gene Rearrangements in the Diagnosis of Lymphoma/Leukemia HAROLD R. SCHUMACHER, DAN PANKOWSKY, AND KARLA M. SENDELBACH The Author’s Reply JEFFREY COSSMAN, CARLETON T. GARRETT, LINDA O. HANSON, AND ELAINE JAFFE Chromosomal Abnormalities in a Low-Grade B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue KATSUYUKI AOZASA The Author’s Reply ANDREW C. WOTHERSPOON AND PETER G. ISAACSON NEWS AND NOTICES 439 TABLE OF CONTENTS Number 4, October 1991 Supplement 1 EDITORIAL Through the Retrospectroscope: A Perspective JAMES LINDER The Bethesda System: A Perspective CHRISTOPHER P. CRUM COMMENTARY Quality Assurance in an Era of Cost Containment LEE H. HILBORNE AND LAURA E. NATHAN Anatomic Pathology in the 1980s: A Decade of New Information and New Challenges ROBERT E. FECHNER Cytopathology During the 1980s SANDRA H. BIGNER AND CATHERINE GREALY COHEN Forensic Pathology in the 1980s LARRY R. TATE, ROGER MITTLEMAN, EDMUND DONOGHUE, Jr., AND ALLEN M. JONES A Review of Transfusion Medicine, 1980-1990 IRA A. SHULMAN Advances in Medical Informatics During the 1980s MICHAEL D. D. MCNEELY Clinical Microbiology in the 1980s FREDERICK A. MEIER MEMORIAL Allen M. Jones, M.D. LARRY R. TATE Number 4, October 1991 Editorials Lactic Dehydrogenase: An Old Enzyme Reborn as a Cancer Marker? MORTON K. SCHWARTZ Ki-67 Staining as a Means to Simplify Analysis of Tumor Cell Proliferation CHARLES L. HITCHCOCK CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES Original Articles Rapid Detection of Epstein-Barr Viral DNA by Nonisotopic Jn Situ Hybridization: Correlation with the Polymerase Chain Reaction MICHAEL SAMOSZUK The Slide Centrifuge Gram Stain as a Urine Screening Method MARSHA L. OLSON, CAROL J. SHANHOLTZER, KEITH E. WILLARD, AND LANCE R. PETERSON Comparison of API Rapid STREP, Baxter MicroScan Rapid Pos ID Panel, BBL Minitek Differential Identification System, IDS RapID STR System, and Vitek GPI to Conventional Biochemical Tests for Identification of Viridans Streptococci CLAUDIA J. HINNEBUSCH, DIANE M. NIKOLAI, AND DAVID A. BRUCKNER CLINICAL CHEMISTRY Original Articles Serum Lactate Dehydrogenase-3 Isoenzyme in Chronic Granulocytic Leukemia ROBERT M. BUCHSBAUM II, FRANK J. LIU, AND JOSE M. TRUJILLO TABLE OF CONTENTS High-Molecular-Weight Alkaline Phosphatase in Serum Has Properties Similar to the Enzyme in Plasma Membranes of the Liver LEE KIHN, ALISON DINWOODIE, AND ROBERT A. STINSON HEMATOPATHOLOGY Original Articles The Role of Gene Rearrangements for Antigen Receptors in the Diagnosis of Lymphoma Obtained by Fine-Needle Aspiration: A Study of 63 Cases with Concomitant Immunophenotyping R. L. KATZ, C. HIRSCH-GINSBERG, C. CHILDS, R. DEKMEZIAN, T. FANNING, N. ORDONEZ, F. CABANILLAS, AND N. SNEIGE Inflammatory Pseudotumor of the Spleen: Report of Two Cases with a Review of the Literature HECTOR MONFORTE-MUNOZ, JAE Y. RO, JOHN T. MANNING, Jr., GENE LANDON, GERARD DEL JUNCO, TERRY S. CARLSON, AND ALBERTO G. AYALA Positive Direct Antiglobulin Tests in Myeloma Patients: Occurrence, Characterization, and Significance BAKUL I. DALAL, SUSAN YOUNG COLLINS, KATHERINE BURNIE, AND ROBERT M. BARR The Platelet Volume-Number Relationship in Patients Infected with the Human Immunodeficiency Virus CHRISTOPHER KOENIG, GURDIP S. SIDHU, AND ROBERT A. SCHOENTAG Intraplatelet Serotonin, 6-Thromboglobulin, and Histamine Concentrations and Thromboxane A, Synthesis in Renal Disease MANUEL A. BARRADAS, VIVIAN A. FONSECA, DALVIR S. GILL, JAMIE Y. JEREMY, ZACHARIAH VARGHESE, ROSEMARY BALLIOD, JOHN MOORHEAD, AND PARESH DANDONA ANATOMIC PATHOLOGY Original Articles Tumor Proliferative Fraction in Solid Malignant Neoplasms: A Comparative Study of Ki-67 Immunostaining and Flow Cytometric Determinations AYSEGUL A. SAHIN, JAE Y. RO, ADEL K. EL-NAGGAR, PATRICIA L. WILSON, KIM TEAGUE, MARK BLICK, AND ALBERTO G. AYALA Glassy Cell Features in Adenosquamous Carcinoma of the Uterine Cervix: Histologic, Ultrastructural, Immunohistochemical, and Clinical Findings MICHAEL J. COSTA, MARY B. KENNY, KARLENE HEWAN-LOWE, AND RANDY JUDD Estrogen and Progesterone Receptors in Lymphangioleiomyomatosis, Epithelioid Hemangioendothelioma, and Sclerosing Hemangioma of the Lung N. PAUL OHORI, SAMUEL A. YOUSEM, ENI SONMEZ-ALPAN, AND THOMAS V. COLBY Desmoplastic Small Cell Tumors of the Peritoneum Coexpressing Mesenchymal and Epithelial Markers LESTER J. LAYFIELD AND CARL LENARSKY Correlation of the Papanicolaou Smear and Human Papillomavirus Type in Women with Biopsy-Proven Cervical Squamous Intraepithelial Lesions GERARD J. NUOVO, LAURA L. WALSH, JOSEPH L. GENTILE, JODY S. BLANCO, JOHN KOULOS, AND ALAN HEIMANN In Memoriam William T. Lockard, Jr., M.D. (1947-1991) BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Freeze Substitution for Histochemical and Immunohistochemical Analysis JOHN W. STIRLING The Authors’ Reply GRAEME I. MURRAY AND STANLEY W. B. EWEN Serum Proteins as Mortality Index in Elderly Patients THIERRY CONSTANS, ANDRE BRUYERE, CHARLES-HENRI RAPIN, AND NAOURI MENSI The Authors’ Reply STEVEN GUTMAN, PAUL KATZ, AND J. KARUZA Sensitivity and Specificity of Clinical Tests GREGORY TETRAULT Standardized Hematology Reports S. M. LEWIS, J. ENGLAND, R. M. ROWAN, AND R. L. VERWILGHEN Teaching Safety Management Guidelines PAUL BACHNER TABLE OF CONTENTS The Author’s Reply MERYL H. HABER NEWS AND NOTICES 558 Number 5, November 1991 Editorials Atypical Intraepithelial Lesions of the Prostate Gland WILLIAM M. MURPHY Diagnosis of Cytomegalovirus Pneumonitis After Bone Marrow Transplantation: Is PCR the Answer? ALEJO ERICE CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASES Original Articles Detection of Enteroviral Infection in Paraffin-Embedded Tissue by the RNA Polymerase Chain Reaction Technique RAYMOND W. REDLINE, DAVID R. GENEST, AND BENJAMIN TYCKO Cytomegalovirus Detection in Bone Marrow Transplant Patients with Idiopathic Pneumonitis: A Clinicopathologic Study of the Clinical Utility of the Polymerase Chain Reaction on Open Lung Biopsy Specimen Tissue LAWRENCE J. BURGART, MICHAEL J. HELLER, MARY J. REZNICEK, TIMOTHY C. GREINER, CYNTHIA J. TENEYCK, AND ROBERT A. ROBINSON Fungi in Megakaryocytes: An Unusual Manifestation of Fungal Infection of the Bone Marrow JUDITH A. FERRY, CAROLYN K. PETTIT, ANDREW E. ROSENBERG, AND NANCY L. HARRIS The Diagnostic Accuracy of Rapid Dipstick Tests to Predict Urinary Tract Infection TERRY A. HURLBUT III, BENJAMIN LITTENBERG, AND THE DIAGNOSTIC TECHNOLOGY ASSESSMENT CONSORTIUM HEMATOPATHOLOGY AND COAGULATION MEDICINE Original Articles Metastatic Carcinoma in Lymph Nodes Simulating “Syncytial Variant” of Nodular Sclerosing Hodgkin’s Disease CARLOS E. BACCHI, RONALD F. DORFMAN, RICHARD T. HOPPE, JOHN K. C. CHAN, AND ROGER A. WARNKE An Evaluation of the Sysmex NE-8000® Hematology Analyzer R. HALLAWELL, C. O’MALLEY, S. HUSSEIN, R. J. DAUER, M. TANTI, A. M. WOOTTON, AND K. M. MCGRATH Elevated Plasminogen Activator Inhibitor Levels Found in Patients with Malignant Conditions JAMES R. NEWLAND AND WILLIAM D. HAIRE How Vitronectin Binds to Activated Glycoprotein IIb-IIIa Complex and Its Function in Platelet Aggregation HIROSHI MOHRI AND TAKAO OHKUBO CLINICAL CHEMISTRY Original Article Lipase and Pancreatic Amylase Activities in Tissues and in Patients with Hyperamylasemia FRED APPLE, PETER BENSON, LYNNE PREESE, STEVEN EASTEP, LAURA BILODEAU, AND GREG HEILER ANATOMIC PATHOLOGY Original Articles Improved Sensitivity and Resolution in the Flow Cytometric DNA Analysis of Human Solid Tumor Specimens: Use of Jn Vitro Fine- Needle Aspiration and Uniform Staining Reagents BRUCE ALLEN BACH, WILLIAM A. KNAPE, MARK G. EDINGER, AND RAYMOND R. TUBBS Morphonuclear Relationship Between Prostatic Intraepithelial Neoplasia and Cancers as Assessed by Digital Cell Image Analysis MICHEL PETEIN, PATRICK MICHEL, ROLAND VAN VELTHOVEN, JEAN-LAMBERT PASTEELS, MICHAEL K. BRAWER, JOHN R. DAVIS, RAYMOND B. NAGLE, AND ROBERT KISS Microcystic Transitional Cell Carcinomas of the Urinary Bladder: A Report of Four Cases ROBERT H. YOUNG AND LAWRENCE R. ZUKERBERG