Simposio FAC-CACI 2016 Congreso Nacional de Cardiologia- Federacion Argentina de Cardiologia(FAC) Cordoba, 23 de Junio 2016 VII “ Alfredo E Rodriguez, MD, PhD, FACC, FSCAI,IAGS Fundador & Director Centro de Estudios en Cardiología Intervencionista (CECI) Jefe de Cardiología Intervencionista Sanatorio Otamendi /Las Lomas Editor en Jefe Revista RACI Director Asociado TCT 2015/2017 (CRF) DECLARO NO TENER CONFLICTOS DE INTERÉS Long-Term Safety and Efficacy of Percutaneous Coronary Intervention With Stenting and Coronary Artery Bypass Surgery for Multivessel Coronary Artery Disease A Meta-Analysis With 5-Year Patient-Level Data From the ARTS, ERACI-II, MASS-II, and SoS Trials Joost Daemen, Eric Boersma, Marcus Flather, Jean Booth, Rod Stables, Alfredo E Rodriguez, Gaston Rodriguez-Granillo, Whady A. Hueb, Pedro A. Lemos, Patrick W. Serruys, Freedom From Death (A) and from Death and Myocardial Infarction (B) Daemen et al. Circulation. 2008;118:1146-1154 HRs for each trial individually and the pooled estimate for all trials (corrected for between-trial outcome) for the end points of all-cause mortality (A) and all-cause death, stroke, and MI (B) Daemen et al. Circulation. 2008;118:1146-1154 PRIMARY OUTCOME – DEATH / STROKE / MI PCI/DES 30 CABG % Logrank P=0.005 , I M PCI/DES / e 20 k o r t S CABG / h t a 10 e D 5-Year Event Rates: 26.6% vs. 18.7% 0 0 1 2 3 4 5 6 Years post-randomization PCI/DES N 953 848 788 625 416 219 40 CABG N s943 814 758 613 422 221 44 Farkouh et al. N Engl J Med 2012;367:2375-84. The SYNTAX lesion score is calculated by grading 11 types of lesions by answering sequential interactive questions YES: Non Guided -Intermediate (50 to 69%) or Severe Stenosis (≥ 70%) with RD ≥ 1.5 mm) Goal Complete Revascularization Sianos G, et al. EuroIntervention. 2005 Aug;1(2):219-27.