This book constitutes the refereed post-conference proceedings of the 7th International Conference on Machine Learning and Intelligent Computing which was held in October 2022 in Jinhua, China. Due to COVID-19 pandemic the conference was held virtually. The 16 full papers of MLICOM 2022 were selected from 41 submissions and are clustered in thematical issues on applications of neural network and deep learning; intelligent massive MIMO communications; machine learning algorithms and intelligent networks.