British Journal of Dermatology Volume 143 July—December 2000 b Published for the British Association of Dermatologists Blackwell oe Science by Blackwell Science British Jour.sal of Dermatology lhe British Journal of Dermatology is owned by and is the official organ of the British Association of Dermatologists. DI DR S.M.BREATHNACH St Thomas’ Hospital, St John’s Institute of Dermatology, Lambeth Palace Road, London SE1 7EH DR N.H.COX Cumberland Infirmary, Department of Dermatology, Newtown Road, Carlisle CA2 7HY EDITORIAL ADVISORY BOARD PROF. D.R.GARROD, Manchester PROF. J.L.REES, Edinburgh PROF. C.E.M.GRIFFITHS, Manchester PROF. H.C.WILLIAMS, Nottingham PROF. I.M.LEIGH, London ASSOCIATE EDITORS DR D.J.EEDY, Craigavon DR A.D.ORMEROD, Aberdeen DR J.A.MCGRATH, London DR N.J.REYNOLDS, Newcastle-upon-Tyne DR C.S.MUNRO, Glasgow DR D.N.SLATER, Rotherham DR G.M.MURPHY, Dublin EDITORIAL ASSISTANT MS C.MOSSOP BAD Office, London The British Journal of Dermatology is published monthly and the subscription prices PO Box 88, Oxford OX2 ONE. U.K. Tel.: +44 1865 206180 or 206038, Fax: +44 for 2000 are £482.00 (Europe), £529.00 (overseas except North America), 1865 206219, e-mail: [email protected]. $841.00 (U.S.A. and Canada), in all cases post free. Personal subscription rates © 2000 British Association of Dermatology. Authorization to photocopy items for are £115.00 (Europe), £126.00 (overseas except North America) and $200.50 internal or personal use or the internal or personal use of specific clients is granted (U.S.A. and Canada). 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Contents IgA antineutrophil cytoplasmic antibodies in cutaneous vasculitis PROVEL-GUITERA, M-C.DIEMERT, J-L.CHARUEL, J-L.LAPORTE, L.MUSSE1 Volume 143, Number 1, July O.CHOSIDOW, J-C.PIETTE AND C.FRANCES The 120-kDa soluble ectodomain of type XVII Historical articles collagen is recognized by autoantibodies in patients Osler and the skin with pemphigoid and linear IgA dermatosis J.A.SAVIN .Y.ROH, C.YEE, Z.LAZAROVA, R.PHALL AND K.B.YANCE} Thomas Bateman MD FLS 1778-1821 Elevated levels of eotaxin and interleukin-5 in blister N.J.LEVELI fluid of bullous pemphigoid: correlation with tissue Hutchinson and Nettleship, nettlerash and albinism eosinophilia W.A.BRANFORD M.WAKUGAWA, K.NAKAMURA, H.HINO, K.TOYAMA, N.HATTORI Rupert Hallam and the development of dermatology H.OKOCHI, H.YAMADA, K.HIRAI, K.TAMAKI AND M.FURUI in Sheffield An open clinical trial of sulphamethoxypyridazine in A.J.G.McDONAGH the treatment of mucous membrane pemphigoid ‘Brooke of Manchester’ M.H.THORNHILL, M.PEMBERTON, J.BUCHANAN AND E.THEAKER M.BHUSHAN AND C.E.M.GRIEFITHS Treatment of erythrodermic cutaneous T-cell Medical history from the Journal lymphoma with intermittent chlorambucil and J.V ERBO\ fluorcortolone therapy Turning points in dermatology during the 20th E.A.COORS AND P.VON DEN DRIESCH century Longtitudinal erythronychia with distal subungual J.A.A-HUNTER keratosis: onychopapilloma of the nail bed and Genetics, past and present, and the rise of systems 30wen''s disease dermatology R.BARAN AND C.PERRIN J.L.REES Post-kala-azar dermal leishmaniasis in the Sudan: The immunopharmacology of skin inflammation: clinical presentation and differential diagnosis the future is already here! E.ZILJSTRA, E.A.G.KHALIL, P.A.KAGER AND A.M.EL-HASSA) M.W.GREAVES Case reports Subcorneal pustular dermatosis type of IgA pemphigus: demonstration of autoantibodies to Original articles desmocollin-1 and clinical review Guidelines for management of tinea capitis H.YASUDA. H.KOBAYASHI. T-HASHIMOTO,. K.ITO! E.M.HIGGINS, L.C.FULLER AND C.H.SMITH J.NAKAMURA The role of lymphocytes in human dermal wound A paraneoplastic mixed bullous skin disease: healing breakdown in tolerance to multiple epidermal D.E.BOYCE, W.D.JONES, ERUGE, K.G.HARDING AND K.MOORI antigens Shingosylphosphorylcholine stimulates contraction of PMUSETTE. PJOLY, D.GILBERI fibroblast-embedded collagen gel S.BELAICH AND V.DESCAMPS K.B.SUHR, R.TSUBOL AND H.OGAWA Pyoderma gangrenosum in a patient with Hexafluoro-1,25-dihydroxyvitamin D; has markedly autoimmune haemolytic anaemia and complement increased potency in inhibiting proliferation of deficiency cultured human keratinocytes compared with E.A.COORS AND P-VON DEN DRIESCH 1,25-dihydroxyvitamin D, Rituximab in cutaneous B-cell lymphoma: a report of I.C.CHEN AND M.EHOLICK two cases Nail bed keratinocytes express an antigen of the R.A.SABROE. F.J.CHILD, A.J. WOOLFORD. M.ESPITTLE AND carcinoembryonic antigen family R.RUSSELL-JONES K.EGAWA, M.KUROKI. Y.INOUE AND T.ONO Angiotropic lymphoma: proliferation of B cells in the Cytological alterations in dermal dendrocytes in vitro: capillaries of cutaneous angiomas evidence for transformation to a non-dendritic l.KOBAYASHI, $.MUNAKATA, H. SUGIURA, M.KOIZUMI. M.SUMIDA phenotype K.MURATA AND H.SHINKAI M.R.MONTEIRO, E.E.MURPHY, N.A.GALARIA, D.WHITAKER-MENEZES Multiple cutaneous immunocytoma with secondary AND G.EMURPHY anetoderma: a report of two cases Cytokine profiles in spontaneously regressing basal FJ.CHILD, A.WOOLLONS, M.L.PRICE, E.CALONJE AND R.RUSSELL-JONES cell carcinomas Malignant melanoma and lymphoproliferative D.A.WONG, G.A.BISHOP. M.A.LOWES, B.COOKE. R.St.C:BARNETSON AND malignancy: is there a shared aetiology? G.M.HALLIDAY D.B.McKENNA, V.R.DOHERTY, K.M.McLAREN AND J.A.A.HUNTER iv CONTENTS Compound heterozygous group A xeroderma Wegener's granulomatosis presenting as neutrophilic pigmentosum patient with a novel mutation and an dermatosis: a case report inherited reciprocal translocation L.GURSES, D.YUCELTEN. A.COMERT, TERGUN AND O.GURBUZ MAEDA, K.SATO, T-TANAKA, H.MINAMI, H.TAGUCHI, T.MIMAKI AND Chronic graft-vs.-host disease with severe cicatrizing K. YOSHIKAWA conjunctivitis mimicking cicatricial pemphigoid Congenital infilitrating lipoma of the upper limb in a A.V.MARZANO, M.FACCHETTI, E.BERTI AND R.CAPUTO patient with von Willebrand disease A case of systemic lupus erythmatosus associated J.M.LASSO, A.ESPANA, M.LZUDAIRE, E.DE ALAVA AND A.BAZAN with cancer of the lung: a paraneoplastic association? Verrucous carcinoma arising in ELOCHE, H.PSCHWARZE. C.DURIEU AND J.BAZEX pseudoepitheliomatous keratotic and micaceous A case of naevus sebaceous associated with familial balanitis, without evidence of human papillomavirus retinoblastoma, multiple lipomata and meningioma EJ CHILD, B.K.KIM, R.GANESAN, S.A.SOUTHERN, C.S.HERRINGTON AND S.D.MORRIS, Z.ONADIM AND R.O.Yt E.CALONJI Angiolymphoid hyperplasia with eosinophilia: Paracoccidioidomycosis (South American successful treatment with pulsed dye laser using the blastomycosis) successfully treated with terbinafine: double pulse technique first case report G.GUPTA AND C.S.MUNRO |.M.OLLAGUE, A.M.DE ZURITA AND G.CALERO Nodular prurigo successfully treated with the pulsed Head actinomycetoma with a double aetiology, dye laser caused by Nocardia brasiliensis and N. asteroides N.SOTO-MENDOZA AND A.BONIFAZ P-N.WOO, T.M.FINCH, C.HINDSON AND 1.S.FOULDS Simultaneous occurence of folliculitis decalvens Successful treatment of solar lentigines by brief gentle capillitii in identical twins cryosurgery using a Kryomed” device K.E.DOUWES, M.LANDTHALER AND R-M.SZEIMIES B.ALMOND-ROESLER AND Ch.C.ZOUBOULIS Synchronous onset of penile lichen sclerosis and vitiligo Correspondence G.E.N.OSBORNE, N.D.FRANCIS AND C.B.BUNKER Nerve growth factor and its receptor system in Actinic damage and squamous cell carcinoma in psoriasis sun-exposed skin affected by vitiligo S.RRAYCHAUDHURI, W-YJIANG, B.R.SMOLLER AND E.M.FARBER K.A.SAARINEN, G.G.LESTRINGANT, LMASOUYE AND P.M.FROSSARD Nerve growth factor and its receptor system in Delayed onset of cutaneous symptoms in psoriasis — reply from author erythropoietic protoporphyria H.A.BULI S.VARMA, A.HAWORTH, M.KEEFE AND A.V.ANSTEY Efficacy of borage oil in patients with atopic eczema Angioblastoma (Nakagawa) with hyperhidrosis, and R.KAPOOR AND A.KLIMASZEWSKI relapse after a 10-year interval Efficacy of borage oil in patients with atopic eczema — T.OHTSUKA, M.SAEGUSA, A.YAMAKAGE AND S.YAMAZAKI reply from author Asymmetric perifluxural exanthem in adults B.M.HENZ A.BAUZA, PREDONDO AND J.FERNANDEZ Management of oral lichen planus Multilocular inoculation tuberculosis of the skin after S.PORTER AND C.SCULLY stay in Africa: detection of mycobacterial DNA using S$100-8 serum protein: a new marker in the polymerase chain reaction diagnosis and monitoring of Langerhans cell P.NENOFF, M.RYTTER, S, SCHUBERT, H.KUHN, M.MITTAG, H-].GLANDER histiocytosis? AND U-EHAUSTEIN S.UGUREL, C.PFOHLER, W:TILGEN AND U.REINHOLD Nasolabial follicular sebaceous casts: a novel Staphylococcal septicaemia complicating treatment of complication of isotretinoin therapy atopic dermatitis with mycophenolate S.AGARWAL AND S.CHARLES-HOLMES \.C.SATCHELL AND R.St.C.BARNETSON Recurrent bullous dermatitis artefacta mimicking Methotrexate-induced exacerbation of urticarial immunobullous disease vasculitis: an unusual adverse reaction A.BORCEA AND M.W.GREAVES R.M.AZURDIA, D.M.GUERIN AND G.R.SHARPE Linear IgA disease: successful treatment with Acute generalized exanthematous pustulosis induced cyclosporin by ingestion of lacquer chicken H.S.YOUNG AND I.H.COULSON Y.M.PARK, J.G.PARK, H.KANG, D.HOUH, D.G.BYUN AND J.W.KIM ‘Microdose’ isotretinoin Papulonecrotic tuberculide in a human R.A.PALMER, S.SIDHU AND P.G.GOODWIN immunodeficiency virus type 1-seropositive patient Circumlesional scaling induced by vitamin D — M.ALSINA, P.CAMPO, A.TOLL, E.MARTINEZ, J.PALOU AND C.HERRERO a guide to compliance Book Reviews |.B ERTH-JONES News and Notices CONTENTS v Volume 143, Number 2, August The A5.1 allele of the major histocompatibility complex class I chain-related gene A is associated Editorial comments with psoriasis vulgaris in Chinese Towards a better understanding of pemphigus L.CHENG, S.Z.ZHANG, C.Y.XIAO, Y.PHOU, L.LI, H.C.LUO, H.YJIANG AND autoimmunity W.0.ZUO M.AMAGAI Human keratinocytes constitutively produce but do Identifying a gene for psoriasis on chromosome 6 not process interleukin 18 (Psors1) ).B.MEE, Y.ALAM AND R.W.GROVES \.D.BURDEN The distribution of pemphigus vulgaris-IgG Measuring the improvement in pulsed dye laser subclasses and their reactivity with desmoglein 3 treated port wine stains and 1 in pemphigus patients and their first-degree S.W.LANIGAN relatives D.KRICHELI, M.DAVID, M.FRUSIC-ZLOTKIN, D.GOLDSMITH, M.RABINO\ J.SULKES AND Y.MILNER Review articles A study of desmoglein 1 autoantibodies in pemphigus Lasers for the dermatologist vulgaris: racial differences in frequency and the K.M.ACLAND AND R.J.BARLOW association with a more severe phenotype Serological markers for melanoma K.E.HARMAN, M.J.GRATIAN, B.S.BHOGAL, S.J.CHALLACOMBE AND L.BROCHEZ AND J-M.NAEYAERT M.M.BLACK IgG, IgA and IgE autoantibodies against the Original articles ectodomain of BP180 in patients with bullous and Rising levels of serum $100 protein precede other cicatricial pemphigoid and linear IgA bullous evidence of disease progression in patients with dermatosis malignant melanoma S.CHRISTOPHORIDIS, L.BUDINGER, L.BORRADORI. T.HUNZIKER C.S.JURY, E.J.McALLISTER AND R.M.MacKII H.EMERK AND M.HERTI Acral cutaneous melanoma in caucasians: clinical A prospective study of the impact of laser treatment features, histopathology and prognosis in 112 on vascular lesions patients G.GUPTA AND D.BILSLAND C.KUCHELMEISTER, G.SCHAUMBURG-LEVER AND C.GARBI Can the response of port-wine stains to laser Differentiation of common benign pigmented treatment be reliably assessed using subjective skin lesions from melanoma by high-resolution methods? ultrasound C.L A.CURRIE AND B.E.MONK C.C.HARLAND, S.G.KALE, PJACKSON, PS.MORTIMER AND Randomized double-blind study of cyclosporin in J.C.BAMBER chronic ‘idiopathic’ urticaria The role of pattern analysis and the ABCD rule of C.E.H.GRATTAN, B.E.O’DONNELL, D.M.FRANCIS, N.NIIMI, R.J.BARLOW dermoscopy in the detection of histological atypia in P-T.SEED, A.KOBZA BLACK AND M.W.GREAVES melanocytic naevi Increased circulating skin-homing cutaneous PCARLI, V.DE GIORGI, D.MASSI AND B.GIANNOTTI lymphocyte-associated antigen (CLA)+ type 2 Cytoplasmic dynein colocalizes with melanosomes in cytokine-producing cells, and decreased CLA+ type 1 normal human melanocytes cytokine-producing cells in atopic dermatitis G.VANCOILLIE, J.LAMBERT, A.MULDER, H.K.KOERTEN, A.M.MOMMAAS Y.TERAKI, THOTTA AND T.SHIOHARA PVAN OOSTVELDT AND J-M.NAEYAERI Effect of house dust mite avoidance measures in A comparative study of Fas and Fas-ligand expression children with atopic dermatitis in melanoma G.RICCI, A.PATRIZI. FSPECCHIA, L.MENNA, PBOTTAU, V.D'ANGELO AND C.SOUBRANE, R.MOUAWAD, E.C.ANTOINE, O.VEROLA, M.GIL-DELGADO M.MASI AND D.KHAYAT Treatment of atopic eczema with oral mycophenolate Expression of Fas and Fas-ligand in primary mofetil cutaneous T-cell lymphoma (CTCL): association K.NEUBER, SCHWARTZ, G.ITSCHERT AND A.TOM DIECK between lack of Fas expression and aggressive types of Increased serum levels of soluble vascular cell CTCL adhesion molecule-1 and soluble E-selectin in patients 0.ZO1-TOLI, M.H.VERMEER, E.DE VRIES, P-VAN BEEK, C.J.L.M.MEJER AND with polymyositis/dermatomyositis R.WILLEMZE M.KUBO, H.IHN, K.YAMANE, N.YAZAWA, K.KIKUCHI, ¥.SOMA AND Detection of Epstein-Barr virus and human K.TAMAKI herpesvirus 7 and 8 genomes in primary cutaneous The role of androgens in determining acne severity in T- and B-cell lyphomas adult women E.NAGORE, E.LEDESMA, C.COLLADO, V.OLIVER, A.PEREZ-PEREZ AND D.CIBULA, M.HILL, O.VOHRADNIKOVA, D.KUZEL, M.FANTA AND A.ALIAGA J.ZIVNY vi CONTENTS Concise communication Lichen myxedematosus in a patient with Change of treatment from cyclosporin to hepatocellular carcinoma mycophenolate mofetil in severe psoriasis P-Y.LO AND T-Y.TZUNG S.C.DAVISON, R.MORRIS-JONES, A.V.POWLES AND L.FRY Cyclophosphamide therapy is effective for bronchiolitis obliterans occurring as a late Case reports manifestation of lupus erythematosus Aggressive subcutaneous panniculitis-like T-cell EWEBER, C.PRIOR, E.KOWALD, M.SCHMUTH AND N.SEPP lymphoma: complete remission with fludarabine, Severe exacerbation of pemphigus vulgaris in mitoxantrone and dexamethasone pregnancy: successful treatment with plasma W.Y.AU, W.M.NG, C.CHOY AND Y.L.KWONG exchange Cutaneous pseudolymphoma, lymphomatoid contact J-O.PIONTEK, H.BORBERG, S.SOLLBERG, T.KRIEG AND N.HUNZELMANN dermatitis type, as an unusual cause of symmetrical Pemphigus foliaceus associated with silicosis upper eyelid nodules H.UEKI, J. TAKAO, EYAMASAKI, N.YODA, M.YAMAGUCHI AND M.KOHDA R.PBRAUN, L.E.FRENCH. R.FELDMANN, P.CHAVAZ AND J-H.SAURAT Recurrent mucinous carcinoma of the skin invading Erythema elevatum diutinum — evidence for to the frontal skull base disease-dependent leukocyte alterations and response \.TANAKA, M.HATOKO, M.KUWAHARA, H.TADA AND T.MURAMATSI to dapsone Verrucous ‘cuniculatum’ carcinoma of the sacral |.GRABBE, N.HAAS, A.MOLLER AND B.M.HENZ region Eosinophilic spongiosis in association with bullous C.D'ANIELLO, L.GRIMALDI, N.MESCHINO, C.BRANDI, A.ANDREASSI AND pemphigoid and chronic lymphocytic leukaemia B.BOSI M.AMEEN, A.C.PEMBROKE, M.M.BLACK AND R.RUSSELL-JONES Neuroendocrine carcinoma of the skin with a Wells’ syndrome associated with recurrent giardiasis lymphoepithelioma-like histological pattern D.CANONNE, A.DUBOST-BRAMA, M.SEGARD, EPIETTE AND J.J-RIOS-MARTIN, A.SOLORZANO-AMORETI, R.GONZALEZ-CAMPORA E.DELAPORTI AND H.GALERA-DAVIDSON Angio-oedema in a neonate with IgG antibodies to Digital arteriovenous malformation parvovirus B19 following intrauterine parvovirus WJ.LOO AND R.P-R.DAWBER B19 infection Subungual abscess: a new ungual side-effect related S.MIYAGAWA, Y.TAKAHASHI, A.NAGAI, Y.YAMAMOTO, A.NAKAGAWA, to docetaxel therapy K.HORI, H.MORIKAWA, A.YOSHIOKA AND T.SHIRAI O.VANHOOTEGHEM, B.RICHERT, A.VINDEVOGHEL, L.VANDENBOSSCHE, Early malignant melanoma manifested as A.VANDEVEIRE AND M.DE LA BRASSINNE longitudinal melanonychia: subungual melanoma PUVA-bath photochemotherapy for congenital may arise from suprabasal melanocytes palmoplantar keratoderma in an 11-year-old girl K.TOMIZAWA PKASKEL, U.LEITER, G.KRAHN, R.SCHIENER, H.PILLEKAMP, R.U.PETER Eruptive pseudoangiomatosis AND M.KERSCHER I.NERI, A.PATRIZI, V.GUERRINI, G.RICCI AND R.CEVENINI Acne keloidalis in caucasian patients on cyclosporin Mycosis fungoides and chronic lymphocytic following organ transplantation leukaemia — composite T-cell and B-cell lymphomas R.M.AZURDIA, R.M.GRAHAM, K.WEISMANN, D.M.GUERIN AND presenting in the skin R.PARSLEW PR.HULL AND A.SAXENA Magnetic Resonance Imaging in the investigation of penile lymphangioma circumscriptum Correspondence G.E.N.OSBORNE, R.J.8.CHINN, N.D.FRANCIS AND C.B.BUNKER Cutaneous thrombotic and necrotizing Cutaneous entrapment of the shed cilium microangiopathy revealing a large granular Y-G.KIM, H-JJOO AND A-Y.LEE lymphocytic leukaemia A palmar epidermoid cyst, showing histological EDEGRAEVE, ILQUERE, O.DEREURE. J-C.GRIS, EDIGNAT-GEORGES. features suggestive of eccrine duct origin, developing L.DURAND AND CJANBON after a bee-sting Successful treatment of chronic leucocytoclastic K.EGAWA, H.KITASATO AND T.ONO vasculitis and persistent ulceration with intravenous Errata immunoglobulin News and Notices C.S.ONG AND E.M.BENSON Book reviews Sweet’s syndrome presenting with lesions resembling eruptive xanthoma S-J.AHN, J-H.CHOI, K-J.SUNG, K-C.MOON AND J-K.KOH Volume 143, Number 3, September Scleredema of Buschke associated with Waldenstrém’s macroglobulinaemia Editorial comment S.RATIP, H.AKIN, M.OZDEMIRLI, D.YUCELTEN, $.KUS, M.EKENEL AND The confusing state of the histiocytoses M.BAYIK A.CHI CONTENTS vii Original articles Phenotypic characteristics of Kaposi's sarcoma Photoadaptation to ultraviolet (UV) radiation in vivo: tumour cells derived from patch-, plaque- and photoproducts in epidermal cells following UVB nodular-stage lesions: analysis of cell cultures isolated therapy for psoriasis from AIDS and non-AIDS patients and review of the V.BATAILLE, VJ.BYKOV, PSASIENI, S.HARULOW, J.CUZICK AND literature K.HEMMINKI l.SIMONART, PHERMANS, L.SCHANDENE AND J.P.VAN VOOREN Antibodies against human herpesvirus 8 in The influence of the vehicle on the synthesis subjects with non-venereal dermatological of porphyrins after topical application of conditions 5-aminolaevulinic acid. Implications in cutaneous C.MASINI. D.D.ABENI, M.S.CATTARUZZA, M.CAPUANO photodynamic sensitization C.PEDICELLI, ECERIMELE. P-PASQUINI, D.CERIMELE, G.FADDA AND \.CASAS, H.FUKUDA, G.DI VENOSA AND A.M.DEL C.BATLLI P.CATTANI Expression and modulation of apoptosis reguiatory Ceramide 2 (N-acetyl sphingosine) is associated molecules in human melanocytes: significance in with reduction in Bcl-2 protein levels by Western vitiligo blotting and with apoptosis in cultured human R.MJ.G..VAN DEN WIJ keratinocytes [.C.LE POOLE. A.J. TIGGES \.DI NARDO, L.BENASSI, C.MAGNONI, A.COSSARIZZA, S.SEIDENARI AND A.GIANNETTI Concise communication A multicentre, single-blind, randomized comparison (Un)usual effects of patch testing? of a fixed clindamycin phospate/tretinoin gel L.KUNKELER, S.C.E.BIKKERS. P.D.BEZEMER AND D.PBR formulation (Velac~) applied once daily and a clindamycin lotion formulation (Dalcin T~ ) Case reports applied twice daily in the topical treatment of acne A case of CD56+ cutaneous aleukaemic granulocytic vulgaris sarcoma with myelodysplastic syndrome CH.C.ZOUBOULIS, L.DERUMEAUX, J.DECROIX, B.MACIEJEWSKA-UDZIELA Y.MURAKAMI, S.NAGAE. E.MATSUISHI. K.IRIE AND M.FURI ECAMBAZARDS AND A.STUHLERT Eccrine syringofibroadenoma in a patient with a burn Stimulatory effects of dibutyryl cyclic adenosine scar ulcer monophosphate on cytokine production by E.ICHIKAWA, Y.FUJISAWA, Y.TATEISHI. S.LMAKADO AND EOTS keratinocytes and fibroblasts Xeroderma pigmentosum: the role of phototesting L-J.ZHOU AND LLONO N.STONE, J.REED. J.MAHOOD, N.HARDWICK AND S.GEORGI Incidence of skin cancer in 5356 patients following Genital lichen sclerosus associated with morphoea organ transplant or systemic sclerosis: clinical and HLA B.LINDELHOF, B.SIGURGEIRSSON, H.GABEL AND R.S.STERN characteristics The use of ivermectin in controlling an outbreak of \.M.FARRELL. PM.MARREN AND EWOJNAROWSKA scabies in a prison Development of squamous cell carcinoma by two B.LEPPARD AND A.E.NABURI high-risk human papillomaviruses (HPVs), a novel Nicotinamide increases biosynthesis of ceramides as HPV-67 and HPV-31 from bowenoid papulosis well as other stratum corneum lipids to improve the \.YONETA, T.YAMASHITA, H-YJIN, A.IWASAWA, S.KONDO AND epidermal permeability barrier K.JIMBOW O.TANNO, Y.OTA, N.KITAMURA, T.KATSUBE AND S.INOUI Bacillary angiomatosis on a region of burned skin in a Change in ultraviolet (UV) transmission following immunocompetent patient the application of vaseline to non-irradiated and M.KARAKAS. M.BABA, V.L.AKSUNGUR \N. H.R.MEMISDOGLI UVB-exposed split skin AND A.UGUZ K.HOFFMAN. K.KASPER, T.GAMBICHLER AND P.ALTMEYER Congenital hypotrichosis due to short anagen Transforming growth factor-B1 and ultraviolet Al M.M.BARRAUD-KLENOVSEK AND R.M.TRUEB radiation increase production of vascular endothelial Atypical fibroxanthoma of the skin and the lower lip growth factor but not of endothelin-1 in human in xeroderma pigmentosum dermal fibroblasts EH.DILEK, N.AKPOLAT. A.METIN AND S.UGRAS S.TROMPEZINSKI. LPERNET, C.MAYOUX, D.SCHMITT AND J.VIAC A keratin 14 ‘knockout’ mutation in recessive Skin tolerance and effectiveness of two hand epidermolysis bullosa simplex resulting in less severe decontamination procedures in everyday hospital use disease M.WINNEFELD, M.A.RICHARD, M.DRANCOURT AND J.J.GROB K.BATTA, E.L RUGG. N.J.WILSON, N.WEST. H.GOODYEAR Experimental irritant contact dermatitis due to M.GRATIAN, PDOPPING-HEPENSTAL. C.MOSS AND R.A.J.EADY cumulative epicutaneous exposure to sodium lauryl Progressive nodular histiocytosis accompanied by sulphate and toluene: single and concurrent systemic disorders application \.GONZALEZ RUIZ. A.LBERNAL RUIZ. H-ARAGONESES FRAILE W.WIGGER-ALBERTI, A.KREBS AND PELSNER MARTINEZ AND M.GARCIA MUNOZ viii CONTENTS Cutaneous Cryptococcus infection due to C.albidus Adaptive antioxidant defence in human dermal associated with Sézary syndrome fibroblasts S.NARAYAN, K.BATTA, PCOLLOBY AND C.Y.TAN C.MEEWES, A.POSWIG, J.DISSEMOND, PBRENNEISEN AND Heterozygous HPS1 mutations in a case of K.SCHARFFETTER-KOCHANEK Hermansky—Pudlak syndrome with giant Codeine caused scarlatiniform pruritic exanthemata;: melansomes patch test negative but positive to oral provocation lHORIKAWA, K.ARAKI, K.FUKAI M.UEDA, T.UEDA, S.ITO AND test M.ICHIHASHI M.MOHRENSCHLAGER, A.GLOCKNER, B.JESSBERGER, W.LWORRET, Hypereosinophilic syndrome presenting as cutaneous M.OLLERT, J.RAKOSKI AND J.RING necrotizing eosinophilic vasculitis and Raynaud's Partial lipodystrophy with hemithoracic phenomenon complicated by digital gangrene atrophy K-A.JANG, Y-S.LIM, J-H.CHOI. K-].SUNG, K-C.MOON AND J-K.KOH S.AKDENIZ, M.HARMAN, M.YALDIZ, H.NAZAROGLI AND A.GUR Correspondence 666 CD56 and terminal deoxynucleotidyl transferase Verruca vulgaris following treatment of vitiligo with positive cutaneous lymphoblastic lymphoma epidermal grafting Y.AMO, K.YONEMOTO, T.OHKAWA, M.SASAKI, Y.ISOBE, K.SUGIMOTO H.Y.KANG J.SONG AND S.IM AND K.KATSUOKA Trichilemmal carcinoma with a cutaneous horn 668 Severe disabling K6ebnerizing ulcerated necrobiosis M-G.SONG H-G.MIN, S-YJUNG, J-M.YANG AND E-S.LEI lipoidica successfully managed with topical PUVA Paecilomyces marquandii cellulitis in a kidney G.K.PATEL, K.G.HARDING AND C.M.MILLS transplant patient Granuloma pyogenicum arising in an arteriovenous L.NALDI, S.LOVATI, C.FARINA, E.GOTTI AND T.CAINELLI haemangioma associated with a port-wine stain Multicentric reticulohistiocytosis associated with J-B.LEE, M.KIM, S-C.LEE AND Y.H.WON Sjégren’s syndrome Dermatomyositis with the features of inclusion body R.MORRIS-JONES. M.WALKER AND C.HARDMAN myositis associated with carcinoma of the bladder: Recurrent self-healing cutaneous mucinosis in an a true association? adult |.M.GRAU AND M.PEREA K.A.JANG, M-H.HAN, J-H.CHOI, K-J.SUNG, K-C.MOON AND J-K.KOH Chronic ulcerative stomatitis: antibodies reacting Localized morphoea, xanthomatosis and primary with the 70-kDa molecule react with epithelial nuclei biliary cirrhosis A.PARODI, E.COZZANI, M.CACCIAPUOTI AND A.REBORA |.R.REED, N.DE LUCA, A.S.McINTYRE AND J.D.WILKINSON Wells’ syndrome and human immunodeficiency virus Unilateral resolution of palmar eczema and infection hyperhidrosis complicated by Horner’s syndrome M.JONES-CABALLERO, S.PPEREZ-SANTOS, G.B.BERMEJO-MARTINEZ, following ipsilateral endoscopic cervical M.L.LECUNA-ECHEVERRiA AND PL.LAZARO-OCHAITA sympathectomy Photodistributed telangiectasia following use of M.M.U.CHOWDHURY, R.HEDGES AND S.W:LANIGAN cefotaxime Management difficulties due to concurrent dermatitis EBORGIA, M.VACCARO, EGUARNERI AND $.P2CANNAVO herpetiformis and variegate porphyria Hypereosinophilic dermatosis: skin lesions as the only S.VARMA AND S.W.LANIGAN manifestation of the idiopathic hypereosinophilic Giant combined dermatofibroma syndrome? l.NUMAJIRI, S.KISHIMOTO, R.SHIBAGAKI, N.KURAMOTO, H.TAKENAKA A.OFFIDANI, M.L.BERNARDINI, O.SIMONETTI. M.GIANGIACOMI, AND H.YASUNO C.SIMONCINI AND G.BOSSI Grover’s disease, despite histological similarity to Blue rubber bleb naevus sydrome: an unusual cause Darier’s disease, does not share an abnormaiity in the of urethral bleeding ATP2A2 gene .R.WILSON, M.J.WESTON, PSINGH AND LEARDLEY |.POWELL, A.SAKUNTABHAI, M.JAMES, S.BURGE AND A.HOVNANIAN Progressive nodular histiocytomas Intranasal buserelin acetate-induced pigmented |. VADOUD-SEYEDI, R.VADOUD-SEYEDI AND G.DE DOBBELEER rosela-like eruption Periorbital heliotrope oedema as the only initial KONO, M.ISHII AND S.TANIGUCHI clinical manifestation of systemic lupus A case of chronic granulamatous skin disease erythematosus in a primigravida associated with deficient HLA class I expression Y-S.DAIL AND H-C.CHIl G.MERTENS, D.DESMET AND M.GIELIS 680 Pyemotes dermatitis caused by indirect contact with Human herpesvirus type 8-positive facial husk rice angiosarcoma developing at the site of botulinum T.UENOTSUCHI, E.SATOH, H.KIRYU AND Y.YANO toxin injection for blepharospasm Oral terbinafine treatment for toenail onychomycosis: S.KARPATI, S.DESAKNAI, M.DESAKNAI, J.BiRO, KNAGY AND follow-up after 5—6 years A. HORVATH L.MOLIN, M.TARSTEDT AND C.ENGMAN CONTENTS ix Pneumocystis carinii pneumonia in a patient with Comparison of red and green light in the treatment of pyoderma gangrenosum treated with cyclosporin Bowen's disease by photodynamic therapy B.D.DE SILVA AND PK.BUXTON C.A.MORTON, C.WHITEHURST, J.V.MOORE AND R.M.MacKIl Peripheral neuropathy as the first manifestation of Leukaemia cutis and leukaemic vasculitis Madelung’s disease S.PAYDAS AND S.ZORLUDEMIR E.SAIZ HERVAS, M.MARTIN LLORENS AND J.LOPEZ ALVAREZ Morphoea is neither associated with features of 686 Haemangioma of the head and neck with subglottic Borrelia burgdorferi infection, nor is this agent involvement and atypical corarctation detectable in lesional skin by polymerase chain R.YATES, S.SYED, V.TSANG AND J.LHARPER reaction Histological changes in naevi with superimposed B.WEIDE, B.SCHITTEK, ‘T-KLYSCZ, K.SCHUZ, M.STARK, G.RASSNER psoriasis B.WILSKE AND C.GARBI G.MASSL AND G.FABRIZI Downregulation of class II molecules on epidermal British Society for Paediatric Dermatology Langerhans cells in Lyme borreliosis Programme and Abstracts M.SILBERER, EKOSZIK, G.STINGL AND E.ABERER Book Reviews Epidemiological study of human herpesvirus-6 and News and Notices human herpesvirus-7 in pityriasis rosea H.KOSUGE, K.TANAKA-TAYA, H.MIYOSHI, K.AMO, R.HARADA .EBIHARA, Y.KAWAHARA, K.YAMANISHI AND T.NISHIKAWA Volume 143, Number 4, October Malassezia globosa as the causative agent of pityriasis versicolor Editorial comment V.CRESPO ERCHIGA, A.OJEDA MARTOS, A.VERA CASANO, A.CRESPO Bowen's disease: where now with therapeutic trials? ERCHIGA AND ESANCHEZ FAJARDO N.H.COX Finasteride increases anagen hair in men with androgenetic alopecia Review article D.VAN NESTE, V.FUH, PSANCHEZ-PEDRENO, E.LOPEZ-BRAN Evaluation of primary prevention initiatives for skin H.WOLFF, D.WHITING, J.ROBERTS, D.KOPERA, J-J.STENE, S.CALVIERI cancer: a review from a U.K. perspective \.TOSTI, E.PRENS, M.GUARRERA, PKANOJIA, WHE AND K.D.KAUFMAN J.MELIA, L.PENDRY, J.R.EISER, C-HARLAND AND S.MOSS A distinct gene close to the hairless locus on Original articles chromosome 8p underlies hereditary Marie Unna Retinoids induce apoptosis in cultured keratinocytes type hypotrichosis in a German family T.C.ISLAM, T.SKARIN, S.SUMITRAN AND R.TOFTGARD S.CICHON, R.KRUSE, A.M.HILLMER, G.KUKUK, M.ANKER, K.ATLAND Spatial and temporal expression of basic fibroblast M.KNAPP. PPROPPING AND M.M.NOTHEN growth factor protein during wound healing of rat Skin disorders in relation to oral contraception and skin other factors, including age, social class, smoking and Y.KIBE, H.TAKENAKA AND S.KISHIMOTO body mass index. Findings in a large cohort study Elafin is induced in epidermis in skin disorders with M.P-VESSEY, R.PAINTER AND J.POWELI dermal neutrophilic infiltration: interleukin 18 and tumour necrosis factor-a stimulate its secretion Concise communications in vitro An extract of cultured A431cells contains major N.TANAKA, A.FUJIOKA, S.TAJIMA, A.ISHIBASHI AND S.HIROSI tissue antigens of autoimmune bullous diseases Expression of small proline rich proteins in neoplastic C.W.LEE and inflammatory skin diseases Effective treatment of frontal hyperhidrosis with M.DE HELLER-MILEV, M.HUBER, R.PANIZZON AND D.HOHI botulinum toxin A Cidofovir inhibits growth of B16 melanoma cells L.KINKELIN, M.HUND, MNAUMANN AND H.HAMM in vivo Efficacy of short-course oral prednisolone in PREDONDO, M.IDOATE, J.C.GALOFRE AND T.SOLANO polymorphic light eruption: a randomized control Trauma and melanoma formation: a true association? trial PKASKEL, P-KIND, S.SANDER. R.U.PETER AND G.KRAHN D.C.PATEL, G.J.BELLANEY, P.T.SEED, J.M.McGREGOR AND J.L.M.HAWK Immunohistochemical expression of bone morphogenetic protein-2 in pilomatricoma IL.KUROKAWA, K.KUSUMOTO, K.BESSHO, Y.OKUBO, H.SENZAKI AND Case reports A.TSUBURA Leucoderma associated with flares of erythrodermic Comparison of cryotherapy with curettage in the cutaneous T-cell lymphomas: four cases treatment of Bowen's disease: a prospective study \.BOULOC, EGRANGE, M.H.DELFAU-LARUE, M.T.DIENG. M.C.TORTEI |.AHMED, J.BERTH-JONES, $.CHARLES-HOLMES, C.J.0'CALLAGHAN AND M.F.AVRIL, J.REVUZ, M.BAGOT, J.WESCHLER FOR THE FRENCH STUDY \.ILCHYSHYN GROUP OF CUTANEOUS LYMPHOMAS x CONTENTS Transient complete remission of metastasized Merkel Extracorporeal photochemotherapy in long term cell carcinoma by high-dose polychemotherapy and treatment of early stage cutaneous T-cell lymphoma autologous peripheral blood stem cell transplantation PRUBEGNI, G.DE ALOE AND M.FIMIANI V.WALDMANN, H.GOLDSCHMIDT, \.JACKEL, M.DEICHMANN, A case of cutaneous relapse of nasal CD56+ natural U.HEGENBART WHARTSCHUH, A.HO AND H.NAHER killer/T-cell lymphoma Livedoid vasculopathy associated with heterozygous S-E.CHANG, J-H.CHOI, K-J.SUNG, K-C.MOON AND J-K.KOH protein C deficiency Factor XII deficiency: a possible cause of livedo with A.BOYVAT, N.KUNDAKCI. M.A.O.BABIKIR AND E.GURGEY ulceration? Imiquimod: a novel treatment for lentigo maligna K.C.SATO-MATSUMURA, TMATSUMURA, H.HAYASHI, l.ATSUMI AND AHMED AND J.BERTH-JONES H.KOBAYASHI Detection of human papillomavirus and response to 899 Acanthosis nigricans with vitiligo and insulin topical 5% imiquimod in a case of stucco keratosis resistance E.STOCKFLETH, J.ROWERT, R.ARNDT, E.CHRISTOPHERS AND T.MEYER M.HARMAN, S.AKDENIZ, H.CETIN AND A.TUZCL Hereditary non-polyposis colorectal cancer associated Psoriatic onycho-pachydermo periostitis: treatment with disseminated superficial porokeratosis. with methotrexate Microsatellite instability in skin tumours A.BAUZA, PREDONDO AND D.AQUERRETA M.TAKATA, ESHIRASAKI T.NAKATANI AND K.TAKEHARA A syndrome combining severe hypotrichosis and Multiple acral fibromas in a patient with familial macular dystrophy: absence of mutations in TIMP retinoblastoma: a cutaneous marker of genes tumour-suppressor gene germline mutation? N.RAISON-PEYRON, P.A.DUVAL, G.BARNEON, L.DURAND, B.ARNAUD, O.DEREURE, D.SAVOY, EDOZ, C.JUNIEN AND J-J.GUILHOI |.MEYNADIER AND C.HAMEL 860 Melkersson—Rosenthal syndrome in childhood: a Melanoma erysipeloides: successful treatment by challenge in differential diagnosis and treatment chemoimmunotherapy PE.ZIEM, C.PFROMMER, S.GOERDT C.E.ORFANOS AND U.BLUME-PEYTAVI U-HILLEN, C.WILLERS AND M.GOOS Psoriasis in association with prolactinoma: three Multiple granular cell tumour in a teenager cases S.DORTA, R.SANCHEZ, M.GARCIA-BUSTINDUY, E.GUIMERA, M.SAEZ, M.SANCHEZ REGANA AND PURBERT MILLET A.NODA, A.MARTIN-HERRERA AND R.GARCIA-MONTELONGO A refractory case of secondary erythermalgia Eruptive multiple sporadic cutaneous piloleiomyomas successfully treated with lumbar sympathetic in a patient with chronic lymphoctic leukemia ganglion block R.VERGANI, R.BETTI, L.UZIEL, E.TOLOMIO AND C.CROSTI M.SEISHIMA, H.KANOH, lIZUMI, M.NIWA, Y.MATSUZAKI, A.TAKASU, 909 Lymphocytoma cutis and chronic infection M.BAN AND Y.KITAJIMA R.U.SIDWELL, P'T.DOE, D.SINETT, N.FRANCIS AND C.B.BUNKER Cutaneous hyalohyphomycosis caused by 910 Simultaneous cutaneous and ungal alternariosis in a Paecilomyces lilacinus in a renal transplant patient renal transplant recipient V.BLACKWELL, K.AHMED, C.O'DOCHERTY AND R,J.HAY C.BAYKAL, R.KAZANCIOGLU, N.BUYUKBABANI, A.V.CELIK, Inherited palmoplantar keratoderma and Y.YEGENOGLU, S.M.KAYACAN, D.SATANA AND M.S.SEVER sensorineural deafness associated with A7445G point An imported case of furuncular myiasis due to mutation in the mitochondrial genome Cordylobia anthropophaga which emerged in Japan L.MARTIN A.TOUTAIN, C.GUILLEN, M.HAFTEK, M.C.MACHET, M.HASEGAWA, HARADA, Y.KOJIMA, A.NAKAMURA, Y.YAMADA, C.TOLEDANO, B.ARBEILLE, G.LORETTE, A.ROTIG AND L.VAILLANT T.KADOSAKA, S.SHINONAGA AND T.NUMATA Papuloverrucous colloid milium: an occupational Bullous Sweet’s syndrome associated with acute variant hepatitis B infection: a new association L.M.MUSCARDIN, M.BELLOCCI AND L.BALUS E.TAN, G.YOSIPOVITCH, Y-C.GIAM AND S.H.TAN A case of unilateral dermatomal cavernous Book Reviews haemangiomatosis News and Notices H.WATABE, M.KASHIMA, T.BABA AND M.MIZOGUCHI Correspondence Volume 143, Number 5, November CD95-ligand (Fas-L)-expressing epidermal lymphocytes Editorial comments G.DE PANFILIS, M.MARCELLI, G.PASOLINI AND C.TORRESANI A controlled study of ultraviolet A sunbed treatment Mobilization of epidermal Langerhans cells of psoriasis L.RYAN J.FERGUSON Mobilization of epidermal Langerhans cells — Dermatological practice and psychiatry reply from authors L.MILLARD KIMBER, M.CUMBERBATCH, R.J.DEARMAN, M.BHUSHAN AND Treatment of warts with immune response modifiers C.E.M.GRIFFITHS E.C.BENTON