TABLE OF CONTENTS JULY TO DECEMBER, 1996 Number 1, July 1996 Editorials Beneath the Surface of the Mud.. . PAUL E. SWANSON The Role of the Hemostasis Laboratory in Cardiopulmonary Bypass Surgery JOHN T. BRANDT Special Articles Use of Irradiated Blood Components: Practice Parameter DONNA PRZEPIORKA, GERMAN F. LEPARC, MARILYN A. STOVALL, JOCHEWED WERCH, AND BENJAMIN LICHTIGER Recommendations for the Reporting of Resected Large Intestinal Carcinomas ASSOCIATION OF DIRECTORS OF ANATOMIC AND SURGICAL PATHOLOGY ANATOMIC PATHOLOGY Original Articles Application of Catalyzed Signal Amplification in Immunodetection of Gonadotropin Subunits in Clinically Nonfunctioning Pituitary Adenomas NAOKO SANNO, AKIRA TERAMOTO, MAKOTO SUGIYAMA, YOSHIKO ITOH, AND R. YOSHIYUKI OSAMURA DNA Ploidy, Cell Cycle Kinetics, and Low Versus High Grade Atypia in Endometrial Hyperplasia HELEN MICHAEL, PATRICIA K. KOTYLO, MICHAEL MOHR, AND LAWRENCE M. ROTH Secondary Pericardial Malignancies: A Critical Appraisal of the Role of Cytology, Pericardial Biopsy, and DNA Ploidy Analysis RICARDO H. BARDALES, MICHAEL W. STANLEY, ROBERT F. SCHAEFER, ROBERTA L. LIBLIT. REBECCA B. OWENS, AND MARK J. SURHLAND Basal Cell (Monomorphic) and Minimally Pleomorphic Adenomas of the Salivary Glands: Distinction From the Solid (Anaplastic) Type of Adenoid Cystic Carcinoma in Fine-Needle Aspiration MICHAEL W. STANLEY, CHARLES A. HORWITZ, SUSAN D. ROLLINS, CELESTE N. POWERS, RICARDO H. BARDALES, SOHEILA KOROURAIN, AND SCOTT J. STERN The Differential Expression of a Novel Intestinal Epithelial Glycoprotein in Various Forms of Inflammatory Bowel Disease CHARLES N. BERNSTEIN, NORMAN M. PETTIGREW, HANI S. EL-GABALAWY, MICHAEL SARGENT, YANGLANG MEU, AND JOHN WILKINS Human Papillomavirus Types 16 and 18 Infection in Infiltrating Adenocarcinoma of the Cervix: PCR Analysis of 138 Cases and Correlation With Histologic Type and Grade PATRIZIA TENTI, SOLANGE ROMAGNOLI, ENRICO SILINI, RITA ZAPPATORE, ARSENIO SPINILLO, PAOLO GIUNTA, ANNA CAPPELLINI, NICOLETTA VESENTINI, CARLO ZARA, AND LUCIANO CARNEVALI HEMATOPATHOLOGY Original Articles Neutrophil Nuclear Segmentation in Mild Cobalamin Deficiency: Relation to Metabolic Tests of Cobalamin Status and Observations on Ethnic Differences in Neutrophil Segmentation RALPH CARMEL, RALPH GREEN, DONALD W. JACOBSEN, AND GEORGE D. QIAN Characterization of Myeloma Cells by Means of Labeling Index, Bone Marrow Histology, and Serum §2-Microglobulin CHRISTIAN M. SCHAMBECK, REINER BARTL, WILMA HOCHTLEN-VOLLMAR, MANFRED WICK, ROLF LAMERZ, AND AHMAD FATEH-MOGHADAM Angiocentric Immunoproliferative Lesions of the Lymph Node MORISHIGE TAKESHITA, MINORU AKAMATSU, KOICHI OHSHIMA, JUNJI SUZUMIYA, MASAHIRO KIKUCHI, NOBUHIRO KIMURA, NAOKUNI UIKE, AND TAKASHI OKAMURA CD20 (Pan-B Cell Antigen) Expression on Bone Marrow-Derived T Cells KENNETH M. ALGINO, RONALD W. THOMASON, DAVID E. KING, MILKA M. MONTIEL, AND FIONA E. CRAIG TABLE OF CONTENTS A Survey of Current Practices in Clinical Flow Cytometry J. PHILIP McCOY, Jr, AND W.R. OVERTON COAGULATION AND TRANSFUSION MEDICINE Original Article Changes in Blood Coagulation During and Following Cardiopulmonary Bypass: Lack of Correlation With Clinical Bleeding ARNOLD B. GELB, ROBERT I. ROTH, JACK LEVIN, MARTIN J. LONDON, RHODA A. NOALL, WALTER W. HAUCK, MICHELE CLOUTIER, EDWARD VERRIER, AND DENNIS T. MANGANO Factor V R506Q Gene Mutation Analysis by PCR-RFLP: Optimization, Comparison With Functional Testing for Resistance to Activated Protein C, and Establishment of Cell Line Controls KARL V. VOELKERDING, LAMBERT WU, ELLIOT C. WILLIAMS, SUZANNE M. HOFFMAN, LINDA M. SABATINI, WAYNE R. BORCHERDING, AND SUZANNE HUBER Sensitivity and Specificity of the APC Resistance Assay in Detection of Individuals With Factor V Leiden JAMES L. ZEHNDER AND RENEE C. BENSON CLINICAL CHEMISTRY Original Articles Clinical Laboratory Investigation of the Sanofi ACCESS CK-MB Procedure and Comparison to Electrophoresis and Abbott IMx GUO DONG MAO, KHOSROW ADELI, A. BRADLEY EISENBREY, AND JOSEPH D. ARTISS Cardiac Troponin T Is Elevated in Asymptomatic Patients With Chronic Renal Failure WENDY L. FRANKEL, DAVID A. HEROLD, THOMAS W. ZIEGLER, AND ROBERT L. FITZGERALD Precision, Accuracy, and Managed Care Implications of a Hand-Held Whole Blood Analyzer in the Prehospital Setting BARTHOLOMEW J. TORTELLA, ROBERT F. LAVERY, JAMES V. DORAN, AND JOHN H. SIEGEL Review Article A Practical Approach to the Laboratory Diagnosis of Dyslipidemia ISHWARLAL JIALAL ABSTRACTS OF PAPERS BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Proliferation Markers in Breast Carcinoma ALBERT A. KESHGEGIAN AND AVITAL CNAAN Results of Autopsy Survey EDITH F. MARLEY The Authors’ Reply RITU NAYAR, CIARAN MANNION, AND ELLIOT WEISENBERG Correction NEWS AND NOTICES INFORMATION FOR AUTHORS Number 2, August 1996 Editorial Testing for Hereditary Hypercoagulability: Activated Protein C Resistance JOHN A. KOEPKE Special Articles Prevention of Transfusion-Associated Cytomegalovirus Infection: Practice Parameter DONNA PRZEPIORKA, GERMAN F. LEPARC, JOCHEWED WERCH, AND BENJAMIN LICHTIGER Rubella Immunity: Defining the Level of Protective Antibody LAURENCE P. SKENDZEL TABLE OF CONTENTS CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASE Original Articles Use of a Single Slide Trichrome-Stained Concentrate for the Detection of Intestinal Parasites: Stained Concentration Procedure for Ova and Parasites DEVON C. HALE, KAREN CARROLL, JAMES R. KUCERA, AND WILLIAM E. ALDEEN Use of Viral Cultures and Serologic Tests for Cytomegalovirus Infection: Rational or Random? WILLIAM E. MANGANO AND ROBERT P. GRUNINGER HEMATOPATHOLOGY Original Articles Lymphoid-Associated Antigen Expression by Acute Myeloid Leukemia TERESA M. LAUNDER, ROBERT A. BRAY, LINDA STEMPORA, MARGIE L. CHENGGIS, AND DIANE C. FARHI CD117/CD34 Expression in Leukemic Blasts STEPHEN J. WELLS, ROBERT A. BRAY, LINDA L. STEMPORA, AND DIANE C. FARHI Mantle Cell Lymphoma: Morphologic Findings in Bone Marrow Involvement JAY WASMAN, NANCY S. ROSENTHAL, AND DIANE C. FARHI The Evaluation of Various Mathematical RBC Indices and Their Efficacy in Discriminating Between Thalassemic and Non- Thalassemic Microcytosis JOHN D. LAFFERTY, MARK A. CROWTHER, MAHMOUD A. ALI, AND MITCHELL LEVINE Case Report Acute Lymphoblastic Leukemia in a Case of Essential Thrombocythemia KRISTINE KRAFTS WORONZOFF-DASHKOFF AND CRAIG E. LITZ ANATOMIC PATHOLOGY Original Articles Lymph Node Recovery From Colorectal Resection Specimens Removed for Adenocarcinoma: Trends Over Time and a Recommendation for a Minimum Number of Lymph Nodes to be Recovered NEAL S. GOLDSTEIN, WELDON SANFORD, MARY COFFEY, AND LESTER J. LAYFIELD Solitary Fibrous Tumor of the Meninges: A Lesion Distinct From Fibrous Meningioma: A Clinicopathologic and Immunohistochemical Study SIDERLEI S. CARNEIRO, BERND W. SCHEITHAUER, ANTONIO G. NASCIMENTO, TAKANORI HIROSE, AND DUDLEY H. DAVIS To Freeze or Not to Freeze: A Comparison of Methods for the Handling of Breast Biopsies With No Palpable Abnormality THEODORE H. NIEMANN, JOEL G. LUCAS, AND WILLIAM L. MARSH, Jr Sialolithiasis: Differential Diagnostic Problems in Fine-Needle Aspiration Cytology MICHAEL W. STANLEY, RICARDO H. BARDALES, JANET BENEKE, SOHEILA KOROURIAN, AND SCOTT J. STERN Aberrations of Chromosomes 9 and 17 in Bilharzial Bladder Cancer as Detected by Fluorescence Jn Situ Hybridization ASHRAF H. GHALEB, JOHN G. PIZZOLO, AND MYRON R. MELAMED Case Report Salivary Duct Carcinoma Secreting Prostate-Specific Antigen GERALD K. JAMES, MORRIS PUDEK, KENNETH W. BEREAN, ELEFTHERIOS P. DIAMANDIS, AND BETTY LOU ARCHIBALD COAGULATION AND TRANSFUSION MEDICINE Original Article Utilization of Testing for Activated Protein C Resistance in a Reference Laboratory SCOTT R. FLORELL AND GEORGE M. RODGERS III Minutes Minutes of the 73rd Annual Business Meeting of the American Society of Clinical Pathologists, September 19, 1995, New Orleans, Louisiana TABLE OF CONTENTS BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Evaluation of the APEC Analyzer ROBERT L. KLICK The Author’s Reply NEIL HARRIS NEWS AND NOTICES Number 3, September 1996 Editorials p53 Gene Alterations in Benign and Malignant Nerve Sheath Tumors SHARON W. WEISS Immunophenotypic Analysis of CD5 Positivity in Paraffin-Embedded Tissues: Still Waiting for an Effective Diagnostic Antibody SHERRIE L. PERKINS Special Article United States Geographic Bacteria Susceptibility Patterns 1995 ASCP SUSCEPTIBILITY TESTING GROUP ANATOMIC PATHOLOGY Original Articles p53 Expression in Neurofibroma and Malignant Peripheral Nerve Sheath Tumor: An Immunohistochemical Study of Sporadic and NF1-Associated Tumors KEVIN C. HALLING, BERND W. SCHEITHAUER, AMY C. HALLING, ANTONIO G. NASCIMENTO, STEVEN C. ZIESMER, PATRICK C. ROCHE, AND PETER C. WOLLAN Image Cytometry Analysis of Feulgen-Stained Nuclei in 72 Lipomatous Lesions Including Atypical Lipomas and Well-Differentiated Liposarcomas JEAN-VALERY BERTHE, DENIS GOLDSCHMIDT, ISABELLE SALMON, CHRISTINE DECAESTECKER, MYRIAM REMMELINK, MICHEL PETEIN, JEAN-LAMBERT PASTEELS, HENDRIK ROELS, HENRY FRIERSON JR., AND ROBERT KISS Barrett Esophagus With Dysplasia: Flow Cytometric DNA Analysis of Routine, Paraffin-Embedded Mucosal Biopsies ELIZABETH A. MONTGOMERY, DAN-PAUL HARTMANN, NORMAN J. CARR, DANIEL A. HOLTERMAN, LESLIE H. SOBIN, AND NORIO AZUMI Detection of Helicobacter pylori in Paraffin-Embedded Gastric Biopsy Specimens by Jn Situ Hybridization TUOMO J. KARTTUNEN, ROBERT M. GENTA, BORIS YOFFE, CHARLES Y. HACHEM, DAVID Y. GRAHAM, AND FOUAD A.K. EL-ZAATARI Intraductal Carcinoma Associated With Invasive Carcinoma of the Breast: A Comparison of the Two Lesions With Implications for Intraductal Carcinoma Classification Systems NEAL S. GOLDSTEIN AND TRACY MURPHY Prospective Correlation of Cervicovaginal Cytologic and Histologic Specimens STACEY N. IBRAHIM, HANNAH R. KRIGMAN, ALICE C. COOGAN, TIM D. WAX, LESLIE G. DODD, REX C. BENTLEY, STANLEY J. ROBBOY, AND WILLIAM W. JOHNSTON Solitary Fibrous Tumor of the Soft Tissue: An Immunohistochemical and Ultrastructural Study TADASHI HASEGAWA, TAKANORI HIROSE, KUNIHIKO SEKI, PENG YANG, AND TOSHIAKI SANO Automated Immunohistochemical Assay for Estrogen Receptor Status in Breast Cancer Using Monoclonal Antibody CC4-5 on the Ventana ES GUY E. NICHOLS, HENRY F. FRIERSON JR., JAMES C. BOYD, AND MARIE H. HANIGAN Case Report Primary Primitive Neuroectodermal Tumor of the Kidney: Case Report and Review of the Literature JAIME FURMAN, WILLIAM M. MURPHY, PETER F. JELSMA, MARK G. GARZOTTO, AND ROBERT D. MARSH TABLE OF CONTENTS HEMATOPATHOLOGY Original Articles Multiparameter Flow-Cytometric Analysis of bc/-2 and Fas Expression in Normal and Neoplastic Hematopoiesis JOSEPH A. DIGIUSEPPE, PATTI LEBEAU, JEANNE AUGENBRAUN, AND MICHAEL J. BOROWITZ Detection and Classification of Acute Leukemia by the Coulter STKS Hematology Analyzer JAMES D. HOYER, CATHERINE P. FISHER, VICKI M. SOPPA, KAY L. LANTIS, AND CURTIS A. HANSON Cytologic Diagnosis of Primary Serous Lymphoma DAN JONES, DAVID S. WEINBERG, GERALDINE S. PINKUS, AND ANDREW A. RENSHAW A Simple Solid-Phase Method for the Identification of Red Cell-Bound Antibodies Without Elution KEISUKE NAGAMINE, TOMOKO KIYOKAWA, HIROSHI AOCHI, MACHIKO OSHIDA, SATORU HAYASHI, YOSHIAKI TOMIYAMA, AND YOSHIYUKI KURATA Antibody NCL-CD%S Fails to Detect Neoplastic CD5+ Cells in Paraffin Sections JONATHAN M. BEN-EZRA AND MICHAEL J. KORNSTEIN CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASE Original Articles Predictive Values of Species’ Identifications From the Vitek Gram-Positive Identification Card Using Clinical Isolates of Coagulase- Negative Staphylococci JAMES A. KELLOGG, MICHAEL D. HANNA, SUSAN J. NELSEN, LISA S. SPRENKLE, MICHAEL L. THOMAS, AND KIMBERLY S. YOUNG Heterogeneity Within Corynebacterium minutissimum Strains Is Explained by Misidentified Corynebacterium amycolatum Strains ANNELIES S. ZINKERNAGEL, ALEXANDER VON GRAEVENITZ, AND GUIDO FUNKE Rapid Detection of Mycobacteria in Inflammatory Necrotizing Granulomas From Formalin-Fixed, Paraffin-Embedded Tissue by PCR in Clinically High-Risk Patients With Acid—Fast Stain and Culture-Negative Tissue Biopsies WILLIAM J. HARDMAN, GUY M. BENIAN, TOM HOWARD, JOHN E. MCGOWAN, JR, BEVERLY METCHOCK, AND JAMES J. MURTAGH CLINICAL CHEMISTRY Original Articles Assessment of a Critical Limit Protocol for Point-of-Care Glucose Testing GIFFORD LUM Comparison of Troponin-T With Other Cardiac Markers in a VA Hospital ROBERT L. FITZGERALD, WENDY L. FRANKEL, AND DAVID A. HEROLD ABSTRACTS OF PAPERS Abstracts of Paper and Poster Presentations, Scientific Sessions of the Fall Meeting of the American Society of Clinical Pathologists and the College of American Pathologists, September 28-October 4, 1996, in San Diego, California. BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Cardiac Markers BERNARD E. STATLAND The Author’s Reply JOSEPH H. KEFFER CDS5+ Extranodal Marginal Zone B-Cell (MALT) Lymphoma DENNIS H. WRIGHT The Authors’ Reply JUDITH A. FERRY AND NANCY L. HARRIS NEWS AND NOTICES TABLE OF CONTENTS Number 4, October 1996 Editorial Statement on Technical Devices for Innovation in Cervical Cytology Screening AMERICAN SOCIETY OF CYTOPATHOLOGY HEMATOPATHOLOGY Original Articles Comparison of bcr-ab/ Protein Expression and Philadelphia Chromosome Analyses in Chronic Myelogenous Leukemia Patients JIE QIANG GUO, JINYING LIAN, ARMAND GLASSMAN, MOSHE TALPAZ, HAGOP KANTARJIAN, ALBERT B. DEISSEROTH, AND RALPH B. ARLINGHAUS Monoclonal Gammopathy of Unknown Significance and Malignant Paraproteinemia in Hong Kong YVETTE I. LOLIN, JOHN CHOW, AND NICHOLAS W.R. WICKHAM Heterogeneity and Clinical Relevance of the Intensity of CD20 and Immunoglobulin Light-Chain Expression in B-Cell Chronic Lymphocytic Leukemia AYALEW TEFFERI, BRIAN J. BARTHOLMAI, THOMAS E. WITZIG, CHIN-YANG LI, CURTIS A. HANSON, AND ROBERT L. PHYLIKY Paraffin Section Immunophenotyping of Acute Leukemias in Bone Marrow Specimens DANIEL A. ARBER AND KAY A. JENKINS Latent Membrane Protein Antibody Reacts With Normal Hematopoietic Precursor Cells and Leukemic Blasts in Tissues Lacking Epstein-Barr Virus Genome by Polymerase Chain Reaction RICHARD D. HAMMER, MARGIE SCOTT, IMRAN SHAHAB, TERENCE T. CASEY, JOHN B. COUSAR, AND WILLIAM R. MACON ANATOMIC PATHOLOGY Original Articles Human Papillomavirus and Epstein-Barr Virus in Sinonasal Schneiderian Papillomas: An Jn Situ Hybridization and Polymerase Chain Reaction Study MICHAEL J. GAFFEY, HENRY F. FRIERSON JR., LAWRENCE M. WEISS, CYNTHIA M. BARBER, GWEN B. BABER, AND MARK H. STOLER CDS5 Immunoreactivity of Epithelial Cells in Thymic Carcinoma and CASTLE Using Paraffin-Embedded Tissue KATHERINE BEREZOWSKI, MARGARET M. GRIMES, ANTHONY GAL, AND MICHAEL J. KORNSTEIN Pleomorphic (Giant and Spindle Cell) Carcinoma Is Genetically Distinct From Adenocarcinoma and Squamous Cell Carcinoma by K-ras-2 and p53 Analysis RONALD M. PRZYGODZKI, MICHAEL N. KOSS, CESAR A. MORAN, JOHN C. LANGER, PATRICIA A. SWALSKY, NANCY FISHBACK, ANKE BAKKER, AND SYDNEY D. FINKELSTEIN A Comparative Study of Apoptosis and Cell Proliferation in Infantile and Adult Fibrosarcomas SHUN-ICHI KIHARA, SANDRA NEHLSEN-CANNARELLA, WOLFF M. KIRSCH, DONALD CHASE, AND A. JULIAN GARVIN Analysis of Immunoglobulin Heavy Chain Gene Rearrangement in Myoepithelial Sialadenitis by Polymerase Chain Reaction ERIC D. HSI, JAVED SIDDIQUI, BERTRAM SCHNITZER, SERHAN ALKAN, AND CHARLES W. ROSS Bronchoalveolar Lavage Cytology in Pulmonary Alveolar Proteinosis ANN BURKHALTER, JAN F. SILVERMAN, MARBRY B. HOPKINS III, AND KIM R. GEISINGER Glandular Cells Derived From Direct Sampling of the Lower Uterine Segment in Patients Status Post-Cervical Cone Biopsy: A Diagnostic Dilemma ROBERT B. HEATON, JR., TREMEL F. HARRIS, DAVID M. LARSON, AND MICHAEL R. HENRY Vimentin-Positive Spider-Shaped Kupffer Cells: A New Clue to Cytologic Diagnosis of Primary and Metastatic Hepatocellular Carcinoma by Fine-Needle Aspiration Biopsy HOWARD HER-JUING WU, LIANG-CHE TAO, AND HARVEY M. CRAMER Review Article Multivariate Statistical Analysis for Anatomic Pathology: Part II: Failure Time Analysis ROBIN T. VOLLMER TABLE OF CONTENTS CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASE Original Articles Disseminated Microsporidiosis Especially Infecting the Brain, Heart, and Kidneys: Report of a Newly Recognized Pansporoblastic Species in Two Symptomatic AIDS Patients ANTHONY T. YACHNIS, JOHANNES BERG, ARIEL MARTINEZ-SALAZAR, BRADLEY S. BENDER, LESLIE DIAZ, AMYN M. ROJIANI, THOMAS A. ESKIN, AND JAN M. ORENSTEIN Rapid Automated Combined Jn Situ Hybridization and Immunohistochemistry for Sensitive Detection of Cytomegalovirus in Paraffin- Embedded Tissue Biopsies LISA M. RIMSZA, ELIZABETH E. VELA, YVETTE M. FRUTIGER, CATHERINE S. RANGEL, MAX SOLANO, LYNNE C. RICHTER, THOMAS M. GROGAN, AND WILLIAM T. BELLAMY IMMUNOPATHOLOGY Original Articles Advantage of Using Both Anionic and Z.witterionic Phospholipid Antigens for the Detection of Antiphospholipid Antibodies PASCALE LAROCHE, MADELEINE BERARD, ANNE-MARIE ROUQUETTE, CHANTAL DESGRUELLE, AND MARIE-CLAIRE BOFFA BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Thromboplastins, Heparin, and Polybrene WALLACE E. CARROLL C-erB-2 in Cervical Carcinoma NEIL E.I. LANGLOIS, LOUISE SKINNER, AND IAIN D. MILLER The Author’s Reply MICHAEL J. COSTA NEWS AND NOTICES Number 4, October 1996, Supplement PATHOLOGY PATTERNS SELECTED TOPICS FROM ADASP Editorial Selected Topics From ADASP ROBERT E. FECHNER FOREFRONTS Quality Assessment in Anatomic Pathology in the Cost-Conscious Era RICHARD J. ZARBO The Autopsy: Simple Thoughts About the Public Needs and How to Address Them BRUCE M. MCMANUS AND SHELLEY M. WOOD The Posthumous Analysis (PHA): An Alternative to the Conventional Autopsy JUAN ROSAI Medicolegal Issues: An Anatomic Pathologist’s Perspective LAWRENCE M. ROTH Digital Imaging in Anatomic Pathology MICHAEL J. O'BRIEN AND ALEXANDER V. SOTNIKOV Subspecialization of Surgical Pathology at the Massachusetts General Hospital W. STEPHEN BLACK-SCHAFFER, ROBERT H. YOUNG, AND NANCY L. HARRIS Subspecialization in Pathology: A European Perspective JAIME PRAT TABLE OF CONTENTS Prostate Cancer: The Problem of Prognostic Factors WILLIAM M. MURPHY History of the Association of Directors of Anatomic and Surgical Pathology WILLIAM J. FRABLE Second Opinions in Surgical Pathology KEVIN O. LESLIE, ROBERT E. FECHNER, AND RICHARD L. KEMPSON The Measurement of Complexity in Surgical Pathology JOHN E. TOMASZEWSKI, SUSAN ABRAHAM, KAREN BELL, ZISSIMOS MOURELATOS, CAROL REYNOLDS, JOHN SEYKORA, AND VIRGINIA A. LIVOLSI Anatomic Pathology Turnaround Times: Use and Abuse M.T. SMITH AND A.J. GARVIN Is There Still a Need for the General Surgical Pathologist? JOHN C. WATTS Number 5, November 1996 Editorials Cysts of the Head and Neck Sampled by Fine-Needle Aspiration: Sources of Diagnostic Difficulty HENRY F. FRIERSON, Jr. Cytology and Mesenchymal Pathology: How Far Will We Go? MITCHELL RYAN CagA and the Outcome of Helicobacter pylori Infection MARTIN J. BLASER AND JEAN E. CRABTREE Special Articles Recommendations for the Reporting of Urinary Bladder Specimens Containing Bladder Neoplasms ASSOCIATION OF DIRECTORS OF ANATOMIC AND SURGICAL PATHOLOGY What Many of Us Are Doing or Should Be Doing in Clinical Pathology: A List of the Activities of the Pathologist in the Clinical Laboratory MICHAEL LAPOSATA COAGULATION AND TRANSFUSION MEDICINE Original Articles Effects of Recombinant Human Tissue Factor Pathway Inhibitor on Thrombus Formation and Its Jn Vivo Distribution in a Rat DIC Model YUSRI ALI ELSAYED, KAZUNORI NAKAGAWA, YU-ICHI KAMIKUBO, KEI-ICHI ENJYOJI, HISAO KATO, AND KATSUO SUEISHI Fellowship Training Programs in Blood Banking and Transfusion Medicine: Results of a National Survey RONALD E. DOMEN, LISA A. RYBICKI, MARK A. POPOVSKY, AND JOHN D. MILAM Improved Characteristics of aPC-Resistance Assay: Coatest aPC Resistance by Predilution of Samples With Factor V Deficient Plasma STYLIANOS KAPIOTIS, PETER QUEHENBERGER, BERND JILMA, SYLVIA HANDLER, INGRID PABINGER-FASCHING, CHRISTINE MANNHALTER, AND WOLFGANG SPEISER CLINICAL MICROBIOLOGY AND INFECTIOUS DISEASE Original Articles Evaluation of the Gen-Probe Amplified Mycobacterium tuberculosis Direct Detection Test MARILYNN R. FAIRFAX Rapid Detection of the Staphylococcal mecA Gene from BACTEC Blood Culture Bottles by the Polymerase Chain Reaction KAREN C. CARROLL, REBECCA B. LEONARD, PATRICIA L. NEWCOMB-GAYMAN, AND DAVID R. HILLYARD TABLE OF CONTENTS Case Report Encephalitozoon (Septata) intestinalis: Cytologic, Histologic, and Electron Microscopic Features of a Systemic Intestinal Pathogen PEIGUO CHU AND A. BRIAN WEST ANATOMIC PATHOLOGY Original Articles Cytologic Findings in Thyroglossal Duct Carcinoma RICARDO H. BARDALES, MARK J. SUHRLAND, SOHEILA KOROURIAN, ROBERT F. SCHAEFER, EHAB Y. HANNA, AND MICHAEL W. STANLEY Cytology of Typical and Atypical Ewing’s Sarcoma/PNET ANDREW A. RENSHAW, ANTONIO R. PEREZ-ATAYDE, JONATHAN A. FLETCHER, AND SCOTT R. GRANTER Relationship Between Composition of Lymphoid Cell Infiltrates in the Liver and Replication Status in Chronic Hepatitis B: An Immunohistochemical Study JEAN-FRANCOIS MOSNIER, BACH-NGA PHAM, FRANCINE WALKER, SYLVIE DUBOIS, FRANCOISE DEGOS, SERGE ERLINGER, AND CLAUDE DEGOTT Quality Control of Proliferation Marker (MIB-1) in Image Analysis Systems Utilizing Cell Culture-Based Control Materials STEPHEN G. RUBY AND ANNE C. MCNALLY Quantitative Immunocytochemical Assays on Frozen Sections of p53: Correlation to the Follow-up of Patients With Breast Carcinomas COLETTE CHARPIN, STEPHANE GARCIA, CORINNE BOUVIER, LUCILE ANDRAC, BENEDICTE DEVICTOR, MARIE-NOELLE LAVAUT, C. ALLASIAC, PASCAL BONNIER, AND LUCIEN PIANA Altered Expression of CD44 in Human Prostate Cancer During Progression MOOLKY NAGABHUSHAN, THOMAS G. PRETLOW, YA-JUN GUO, SAEID B. AMINI, THERESA P. PRETLOW, AND MAN-SUN SY Expression of the bc/-2 Oncoprotein in Meningiomas JEAN-FRANCOIS MOSNIER, ANNE GENTIL PERRET, JACQUES BRUNON, AND SIMONNE BOUCHERON Case Reports Female Pseudohermaphroditism Due to Congenital Adrenal Hyperplasia Complicated by Adenocarcinoma of the Prostate and Clear Cell Carcinoma of the Endometrium JEFFREY L. WINTERS, PHILLIP H. CHAPMAN, DEBORAH E. POWELL, EVELYN R. BANKS, WILLIAM R. ALLEN, AND DAVID P. WOOD, Jr. An Unusual, Recurring Breast Tumor With Features of Eccrine Spiradenoma: A Case Report LUIGI PANICO, ANTONiO D’ANTONIO, ROSISTELLA CHIACCHIO, PAOLO DELRIO, GIUSEPPE PETRELLA, AND GUIDO PETTINATO HEMATOPATHOLOGY Original Articles Gastric Non-Hodgkin Lymphomas of Mucosa-Associated Lymphoid Tissue Are not Associated With More Aggressive Helicobacter pylori Strains as Identified by CagA DAPHNE bE JONG, RENE W.M. VAN DER HULST, GERARD PALS, WILLEMIEN C. VAN DIJK, ARIE VAN DER ENDE, GUIDO N.J. TYTGAT, BABS G. TAAL, AND HENK BOOT Myelodysplastic Syndromes and Acute Myeloid Leukemia in Connective Tissue Disease After Single-Agent Chemotherapy NANCY S. ROSENTHAL AND DIANE C. FARHI Hematologic Disorders Associated With Deletions of Chromosome 20q: A Clinicopathologic Study of 107 Patients PAUL J. KURTIN, GORDON W. DEWALD, DAVID J. SHIELDS, AND CURTIS A. HANSON Case Report Fine-Needle Aspiration Biopsy Findings in a Case of Follicular Dendritic Cell Tumor DAVID DUSENBERY AND CHARLES G. WATSON BOOK REVIEWS CORRESPONDENCE AND CORRECTIONS Splenic Pathology in Different Forms of Traumatic Injury CINTHIA B. DRACHENBERG AND JOHN C. PAPADIMITRIOU The Author’s Reply DIANE FARHI TABLE OF CONTENTS Streptococcus Isolates FREDERIC BERT, MORGANE LANCELIN, AND NICOLE LAMBERT-ZECHOVSKY NEWS AND NOTICES Number 6, December 1996 Editorial The PT and the Pendulum SCOTT R. FLORELL AND GEORGE M. RODGERS III CLINICAL CHEMISTRY Original Article Comprehensive Review of Cocaethylene and Cocaine Concentrations in Patients DAVID N. BAILEY Comparison of Cardiac Troponin I and Lactate Dehydrogenase Isoenzymes for the Late Diagnosis of Myocardial Injury JOSEPH T. MARTINS, DAI J. LI, LELAND B. BASKIN, ISHWARLAL JIALAL, AND JOSEPH H. KEFFER Review Article Hyperhomocysteinemia: An Emerging and Important Risk Factor for Thromboembolic and Cardiovascular Disease SUSAN C. GUBA, LOUIS M. FINK, AND VIVIAN FONSECA HEMATOPATHOLOGY Original Articles Diurnal Change of Blood Count Analytes in Normal Subjects A. RICHARDSON JONES, DEAN TWEDT, WILLIAM SWAIM, AND EUGENE GOTTFRIED p53 Expression in Reed-Sternberg Cells Does Not Correlate With Gene Mutations in Hodgkin’s Disease KOJO S.J. ELENITOBA-JOHNSON, L. JEFFREY MEDEIROS, JILA KHORSAND, AND THOMAS C. KING Immunophenotypic Identification of Sezary Cells in Peripheral Blood STEVEN A. BOGEN, DINA PELLEY, MARIA CHARIF, MARGARET MCCUSKER, HOWARD KOH, FRANCINE FOSS, MARIA GARIFALLOU, CHARLES ARKIN, AND DOROTHEA ZUCKER-FRANKLIN Differentiation of Primary and Secondary Cutaneous B-Cell Lymphoma by Southern Blot Analysis NORBERT SEPP, KATHARINA WEYRER, MARGOT HAUN, BERNHARD ZELGER, JOSEF THALER, VIKTORIA FABER, PETER FRITSCH, AND KURT GRUNEWALD ANATOMIC PATHOLOGY Original Articles Sorting Out Mix-Ups: The Provenance of Tissue Sections May Be Confirmed by PCR Using Microsatellite Markers D. SEAN O’BRIAIN, ORLA SHEILS, SUZANNE MCELWAINE, SHAUN R. MCCANN, AND MARK LAWLER Multinucleate Giant Cells in Papillary Thyroid Carcinoma: A Morphologic and Immunohistochemical Study GERARDO E. GUITER AND RONALD A. DELELLIS Fine-Needle Aspiration Biopsy of Synovial Sarcoma: A Cytomorphologic Analysis of Primary, Recurrent, and Metastatic Tumors SCOTT E. KILPATRICK, LISA A. TEOT, MICHAEL W. STANLEY, WILLIAM G. WARD, PAUL D. SAVAGE, AND KIM R. GEISINGER Correlation Between MIB-1 Staining Index and the Immunoreactivity of p53 Protein in Recurrent and Non-recurrent Meningiomas AKIRA MATSUNO, TADASHI NAGASHIMA, REIKO MATSUURA, HIDEKI TANAKA, MAKOTO HIRAKAWA, MINEKO MURAKAMI, AKIRA TAMURA, AND TAKAAKI KIRINO Gastric Pathology in Meckel’s Diverticulum: Review of Cases Resected Between 1965 and 1995 GABOR CSERNI