PROGRESS IN BRAIN RESEARCH VOLUME 119 ADVANCES IN BRAIN VASOPRESSIN Other Volumes in PROGRESS IN BRAIN RESEARCH Volume 96: Volume 97: Volume 98: Volume 99: Volume 100: Volume 101: Volume 102: Volume 103: Volume 104: Volume 105: Volume 106: Volume 107: Volume 108: Volume 109: Volume 110 Volume 1 1 1: Volume 112: Volume 113: Volume 114: Volume 115: Volume 116: Volume 117: Volume 1 18: Neurobiology of Ischemic Brain Damage, by K. Kogure, K.-A. Hossmann and B.K. Siesjo (Eds.) - 1993, ISBN 0-444-89603-1. Natural and Artificial Control of Hearing and Balance, by J.H.J. Allum D.J. Allum- Mecklenburg, F.P. Harris and R. Probst (Eds.) - 1993, ISBN 0-444 81252-0. Cholinergic Function and Dysfunction, by A.C. Cuello (Ed.) - 1993, ISBN 0-444- Chemical Signalling in the Basal Ganglia, by G.W. Arbuthnott and P.C. Emson (Eds.) - Neuroscience: From the Molecular to the Cognitive, by F.E. Bloom (Ed.) - 1994, ISBN Biological Function of Gangliosides, by L. Svennerholm et al. (Eds.) - 1994, ISBN 0- The Self-organizing Brain: From Growth Cones to Functional Networks, by J. van Pelt, M.A. Comer, H.B.M. Uylings and F.H. Lopes da Silva (Eds.) - 1994, ISBN 0-444- Neural Regeneration, by F.J. Seil (Ed.) - 1994, ISBN 0-444-81727-1. Neuropeptides in the Spinal Cord, by F. Nyberg, H.S. Sharma and Z. Wiesenfeld- Gene Expression in the Central Nervous System, by A.C.H. Yu et al. (Eds.) -1995, Current Neurochemical and Pharmacological Aspects of Biogenic Amines, by P.M. Yu, K.F. Tipton and A.A. Boulton (Eds.) - 1995, ISBN 0-444-81938-X. The Emotional Motor System, by G. Holstege, R. Bander and C.B. Saper (Eds.) - Neural Development and Plasticity, by R.R. Mize and R.S. Erzurumlu (Eds.) -1996, Cholinergic Mechanisms: From Molecular Biology to Clinical Significance, by J. Klein and K. Liiffelholz (Eds.) - 1996, ISBN 0-444-82166-X. Towards the Neurobiology of Chronic Pain, by G. Carli and M. Zimmermann (Eds.) - Hypothalamic Integration of Circadian Rhythms, by R.M. Buijs, A. Kalsbeek, H.J. Romijn, C.M.A. Pennartz and M. Mirmiran (Eds.) - 1996, ISBN 0-444-82443-X. Extrageniculostriate Mechanisms Underlying Visually-Guided Orientation Behavior, by M. Norita, T. Bando and B.E. Stein (Eds.) - 1996, ISBN 0-444-82347-6. The Polymodal Receptor: A Gateway to Pathological Pain, by T. Kumazawa, L. Kruger The Cerebellum: From Structure to Control, by C.I. de Zeeuw, P. Strata and J. Voogd Brain Function in Hot Environment, by H.S. Sharma and J. Westmau (Eds.) - 1998, The Glbtamate Synapse as a Therapeutical Target: Molecular Organization and Pathol- ogy of the Glutamate Synapse, by O.P. Ottersen, I.A. Langmoen and L. Gjerstad (Eds.) Neuronal Degeneration and Kegeneration: From Basic Mechaniqms to Prospects for Therapy, by F. van Leeuwen, A. Salehi, R. Giger, A. Holmaat and J. Verhaagen (Eds.) - Nitric Oxide in Brain Development, Plasticity, and Disease, by R.R. Mize, T.M. Dawson, V.L. Dawson and M.J. Friedlander (Eds.) - 1998, ISBN 0-444-82885-0. 897 17-8. 1993, ISBN 0-444-81562-7. 0-444-8 1678-X. 444-81658-5. 81819-7. Hallin (Eds.) - 1995, ISBN 0-444-81719-0. ISBN 0-444-81852-9. 1996, ISBN 0-444-81 962-2. ISBN 0-444-82433-2. 1996, ISBN 0-444-82149-X. and K. MiZUm~ra @IS.) - 1996, ISBN 0-444-82473-1. (Eds.) - 1997. ISBN 0-444-82313-1. ISBN 0-444-82377-8. - 1998, ISBN 0-444-82754-4. 1998, ISBN 0-444-82817-6. PROGRESS IN BRAIN RESEARCH VOLUME 119 ADVANCES IN BRAIN VASOPRESSIN EDITED BY I.J.A. URBAN, J.P.H. BURBACH AND D. DE WED Department of Medical Pharmacology, Rudolf Magnus Institute for Neurosciences, Utrecht University, 3584 CG Utrecht. The Netherlands ELSEVIER 1998 AMSTERDAM - LAUSANNE - NEW YORK - OXFORD - SHANNON - SINGAPORE - TOKYO ELSEVIER SCIENCE B.V. Sara Burgerhartstraat 25 P.O. Box 211, lo00 AE Amsterdam, The Netherlands 0 1998 Elsevier Science B.V. All rights reserved This work and the individual contributions contained in it are protected under copyright by Elsevier Science B.V., and the following terms and conditions apply to its use: Photocopying Single photocopies of single chapters may be made for personal use a allowed by national copyright laws. Permission of the publisher and payment of a fee is required for all other photocopying, including multiple or systematic copying, copying for advertising or promotional purposes, resale, and all forms of document delivery. Special rates are available for educational institutions that wish to make photocopies for non-profit educational classroom use. Permissions may be sought directly from Elsevier Science Rights & Permissions Department, PO Box 800, Oxford OX5 IDX, UK, phone: (4) 1865 843830, fax: (4) 1865 853333, e-mail: